|
44
|
128
|
4yh3A |
Crystal structure of human brd4(1) in complex with 4-[(2e)-3-(4-methoxyphenyl)-2-phenylprop-2-enoyl]-3,4-dihydroquinoxalin-2(1h)-one (compound 19a) |
|
39
|
115
|
5cugA |
Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2b (baz2b) in complex with 4-acetamidobenzoic acid (sgc - diamond i04-1 fragment screening) |
|
39
|
115
|
5cq4A |
Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2b (baz2b) in complex with 3'-hydroxyacetophenone (sgc - diamond i04-1 fragment screening) |
|
42
|
115
|
5cqaA |
Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2b (baz2b) in complex with n-methyl-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carboxamide (sgc - diamond i04-1 fragment screening) |
|
43
|
125
|
5d3sA |
First bromodomain of brd4 bound to inhibitor xd44 |
|
41
|
127
|
5d3pA |
First bromodomain of brd4 bound to inhibitor xd41 |
|
50
|
183
|
4yatA |
Crystal structure of trim24 phd-bromodomain complexed with n-(1,3-dimethyl-2-oxo-2,3-dihydro-1h-1,3-benzodiazol-5-yl)-4-methoxybenzene-1-sulfonamide (5b) |
|
40
|
133
|
5ctlA |
Crystal structure of the first bromodomain of human brd4 in complex with benzo[cd]indol-2(1h)-one ligand |
|
39
|
115
|
5cudA |
Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2b (baz2b) in complex with 6-chloropurine (sgc - diamond i04-1 fragment screening) |
|
41
|
115
|
5cq7A |
Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2b (baz2b) in complex with n,n-dimethylquinoxaline-6-carboxamide (sgc - diamond i04-1 fragment screening) |
|
42
|
131
|
5cqtA |
Crystal structure of the first bromodomain of human brd4 in complex with benzo[cd]indol-2(1h)-one ligand |
|
45
|
127
|
5cp5A |
Crystal structure of the first bromodomain of human brd4 in complex with benzo[cd]indol-2(1h)-one ligand |
|
54
|
183
|
4ybtA |
Crystal structure of trim24 phd-bromodomain complexed with n-{1,3-dimethyl-2-oxo-6-[3-(oxolan-3-ylmethoxy)phenoxy]-2,3-dihydro-1h-1,3-benzodiazol-5-yl}-1-methyl-1h-imidazole-4-sulfonamide (7l) |
|
42
|
114
|
5cq5A |
Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2b (baz2b) in complex with 2,3-ethylenedioxybenzoic acid (sgc - diamond i04-1 fragment screening) |
|
39
|
115
|
5cq3A |
Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2b (baz2b) in complex with 6-hydroxypicolinic acid (sgc - diamond i04-1 fragment screening) |
|
38
|
113
|
4yk0A |
Crystal structure of the cbp bromodomain in complex with cpi098 |
|
40
|
115
|
5cgpA |
Selective pharmacological inhibition of the creb binding protein bromodomain regulates inflammatory cytokines in macrophages and rgs4 in neurons |
|
41
|
115
|
5cq8A |
Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2b (baz2b) in complex with 4'-hydroxyacetophenone (sgc - diamond i04-1 fragment screening) |
|
43
|
130
|
5cpeA |
Crystal structure of the first bromodomain of human brd4 in complex with benzo[cd]indol-2(1h)-one ligand |
|
41
|
115
|
5cq6A |
Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2b (baz2b) in complex with 2,6-pyridinedicarboxylic acid (sgc - diamond i04-1 fragment screening) |
|
53
|
184
|
4yc9A |
Crystal structure of trim24 phd-bromodomain complexed with n-(6-{3-[4-(dimethylamino)butoxy]-5-propoxyphenoxy}-1,3-dimethyl-2-oxo-2,3-dihydro-1h-1,3-benzodiazol-5-yl)-3,4-dimethoxybenzene-1-sulfonamide (8i) |
|
43
|
127
|
4xy9A |
Crystal structure of the first bromodomain of human brd4 in complex with a 2-amine-9h-purine ligand |
|
40
|
116
|
4xubA |
Crystal structure of the bromodomain of human baz2b in complex with baz2-icr chemical probe |
|
42
|
113
|
4xy8A |
Crystal structure of the bromodomain of brd9 in complex with a 2-amine-9h-purine ligand |
|
35
|
115
|
4y03A |
Crystal structure of the fifth bromodomain of human pb1 in complex with salicylic acid |
|
41
|
116
|
4xuaA |
Crystal structure of the bromodomain of human baz2b in complex with e11919 baz2-icr analogue |
|
44
|
127
|
4xyaA |
Crystal structure of the first bromodomain of human brd4 in complex with a 2-amine-9h-purine ligand |
|
37
|
109
|
4uyeA |
Bromodomain of human brpf1 with n-1,3-dimethyl-2-oxo-6-(piperidin-1- yl)-2,3-dihydro-1h-1,3-benzodiazol-5-yl-2-methoxybenzamide |
|
41
|
124
|
4whwA |
Direct photocapture of bromodomains using tropolone chemical probes |
|
44
|
126
|
4uydA |
N-terminal bromodomain of human brd4 with 1,3-dimethyl-2-oxo-2,3- dihydro-1h-1,3-benzodiazole-5-carboxamide |
|
39
|
119
|
4whuA |
Bromo domain of creb binding protein |
|
37
|
101
|
4uiuA |
Bromodomain of human brd9 with 7-(3,4-dimethoxyphenyl)-n-(1,1-dioxo-1- thian-4-yl)-5-methyl-4-oxo-4h,5h-thieno-3,2-c-pyridine-2-carboxamide |
|
41
|
126
|
4x2iA |
Discovery of benzotriazolo diazepines as orally-active inhibitors of bet bromodomains: crystal structure of brd4 with cpi-13 |
|
45
|
127
|
4uizA |
N-terminal bromodomain of human brd4 with 7-(3,4-dimethoxyphenyl)-2-(4-methanesulfonylpiperazine-1-carbonyl)-5-methyl-4h,5h-thieno-3,2-c- pyridin-4-one |
|
43
|
127
|
4wivA |
Crystal structure of the first bromodomain of human brd4 in complex with a novel inhibitor umb32 (n-tert-butyl-2-[4-(3,5-dimethyl-1,2-oxazol-4-yl) phenyl]imidazo[1,2-a]pyrazin-3-amine) |
|
38
|
109
|
4uyhA |
N-terminal bromodomain of human brd2 with 1-((2r,4s)-2-methyl-4-(phenylamino)-6-(4-(piperidin-1-ylmethyl)phenyl)-3,4-dihydroquinolin-1(2h)-yl)ethanone |
|
35
|
101
|
4uivA |
Bromodomain of human brd9 with n-(1,1-dioxo-1-thian-4-yl)-5-methyl-4- oxo-7-3-(trifluoromethyl)phenyl-4h,5h-thieno-3,2-c-pyridine-2- carboximidamide |
|
40
|
109
|
4uygA |
C-terminal bromodomain of human brd2 with i-bet726 (gsk1324726a) |
|
38
|
108
|
4uyfB |
N-terminal bromodomain of human brd2 with i-bet726 (gsk1324726a) |
|
39
|
119
|
4uyfA |
N-terminal bromodomain of human brd2 with i-bet726 (gsk1324726a) |
|
54
|
130
|
4tu6A |
Crystal structure of apo atad2a bromodomain with n1064 alternate conformation |
|
37
|
101
|
4uiwA |
Bromodomain of human brd9 with n-(1,1-dioxo-1-thian-4-yl)-5-ethyl-4- oxo-7-3-(trifluoromethyl)phenyl-4h,5h-thieno-3,2-c-pyridine-2- carboximidamide |
|
41
|
126
|
4uixA |
N-terminal bromodomain of human brd4 with 7-(3,4-dimethoxyphenyl)-n-(1,1-dioxo-1-thian-4-yl)-5-methyl-4-oxo-4h,5h-thieno-3,2-c-pyridine-2- carboxamide |
|
53
|
130
|
4tt2A |
Crystal structure of atad2a bromodomain complexed with h4(1-20)k5ac peptide |
|
39
|
117
|
4rvrA |
Crystal structure of the bromodomain of human baz2b in complex with gsk2801 |
|
53
|
130
|
4tt6A |
Crystal structure of atad2a bromodomain double mutant n1063a-y1064a in apo form |
|
55
|
130
|
4tt4A |
Crystal structure of atad2a bromodomain complexed with h3(1-21)k14ac peptide |
|
42
|
112
|
4tqnA |
Crystal structure of the bromodomain of human crebbp in complex with ul04 |
|
42
|
112
|
4ts8A |
Crystal structure of the bromodomain of human crebbp in complex with xz08 |
|
50
|
130
|
4tz2A |
Fragment-based screening of the bromodomain of atad2 |
