83
|
293
|
5oo3A |
Cdk2(f80c, c177a) with covalent ligand at f80c |
82
|
295
|
5osjA |
Cdk2(wt) with covalent adduct at c177 |
79
|
295
|
5oo1A |
Cdk2(f80c, c177a) covalent adduct with c37 at f80c |
81
|
296
|
5nevA |
Cdk2/cyclin a in complex with compound 73 |
108
|
363
|
5ceiA |
Crystal structure of cdk8:cyclin c complex with compound 22 |
88
|
325
|
5acbC |
Crystal structure of the human cdk12-cyclink complex |
98
|
363
|
5hbhA |
Cdk8-cycc in complex with 5-{5-chloro-4-[1-(2-methoxy-ethyl)-1,8-diaza-spiro[4.5]dec-8-yl]-pyridin-3-yl}-1-methyl-1,3-dihydro-benzo[c]isothiazole 2,2-dioxide |
94
|
361
|
5hvyA |
Cdk8/cycc in complex with compound 20 |
103
|
362
|
5hbeA |
Cdk8-cycc in complex with 8-[3-chloro-5-(1-methyl-2,2-dioxo-2, 3-dihydro-1h-2l6-benzo[c]isothiazol-5-yl)-pyridin- 4-yl]-1-oxa-3,8-diaza-spiro[4.5]decan-2-one |
97
|
362
|
5hnbA |
Cdk8-cycc in complex with [6-hydroxy-3-(3-methyl-benzyl)-1h-indazol-5-yl]-((s)-3-hydroxy-pyrrolidin-1-yl)-methanone |
98
|
313
|
5g6vA |
Crystal structure of the pctaire1 kinase in complex with inhibitor |
75
|
295
|
5fp5A |
Structure of cyclin-dependent kinase 2 with small-molecule ligand 4- fluorobenzoic acid (at222) in an alternate binding site. |
69
|
291
|
5fwlK |
Atomic cryoem structure of hsp90-cdc37-cdk4 complex |
53
|
209
|
5fwpK |
Atomic cryoem structure of hsp90-cdc37-cdk4 complex |
71
|
291
|
5fwmK |
Atomic cryoem structure of hsp90-cdc37-cdk4 complex |
52
|
209
|
5fwkK |
Atomic cryoem structure of hsp90-cdc37-cdk4 complex |
102
|
362
|
5fgkA |
Cdk8-cycc in complex with 8-[3-(3-amino-1h-indazol-6-yl)-5-chloro- pyridine-4-yl]-2,8-diaza-spiro[4.5]decan-1-one |
76
|
294
|
5fp6A |
Structure of cyclin-dependent kinase 2 with small-molecule ligand 3-(4,7-dichloro-1h-indol-3-yl)prop-2-yn-1-ol (at17833) in an alternate binding site. |
96
|
331
|
5efqA |
Crystal structure of human cdk13/cyclin k in complex with adp-aluminum fluoride |
76
|
298
|
5anoA |
Crystal structure of cdk2 processed with the crystaldirect automated mounting and cryo-cooling technology |
81
|
297
|
5aniA |
Crystal structure of cdk2 in complex with 6-chloro-7h-purine processed with the crystaldirect automated mounting and cryo-cooling technology |
79
|
298
|
5ankA |
Crystal structure of cdk2 in complex with 2,4,6-trioxo-1-phenyl- hexahydropyrimidine-5-carboxamide processed with the crystaldirect automated mounting and cryo-cooling technology |
75
|
297
|
5angA |
Crystal structure of cdk2 in complex with 7-hydroxy-4-(morpholinomethyl)chromen-2-one processed with the crystaldirect automated mounting and cryo-cooling technology |
85
|
296
|
5anjA |
Crystal structure of cdk2 in complex with n-(9h-purin-6-yl)thiophene- 2-carboxamide processed with the crystaldirect automated mounting and cryo-cooling technology |
84
|
298
|
5aneA |
Crystal structure of cdk2 in complex with 6-methoxy-7h-purine processed with the crystaldirect automated mounting and cryo-cooling technology |
78
|
293
|
5andA |
Crystal structure of cdk2 in complex with 2-imidazol-1-yl-1h- benzimidazole processed with the crystaldirect automated mounting and cryo-cooling technology |
85
|
299
|
5cyiA |
Cdk2/cyclin a covalent complex with 6-(cyclohexylmethoxy)-n-(4-(vinylsulfonyl)phenyl)-9h-purin-2-amine (nu6300) |
77
|
298
|
5d1jA |
Crystal structure of cyclin-dependent kinase 2 (cdk2-wt) complex with n-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl] methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide (bms-387032) |
81
|
289
|
4yc6A |
Cdk1/cks1 |
79
|
298
|
4yc3A |
Cdk1/cyclinb1/cks2 apo |
78
|
292
|
4y72A |
Human cdk1/cyclinb1/cks2 with inhibitor |
55
|
290
|
4tthB |
Crystal structure of a cdk6/vcyclin complex with inhibitor bound |
79
|
295
|
4rj3A |
Cdk2 with egfr inhibitor compound 8 |
88
|
324
|
4or5A |
Crystal structure of hiv-1 tat complexed with human p-tefb and aff4 |
84
|
323
|
4ogrA |
Crystal structure of p-tefb complex with aff4 and tat |
98
|
331
|
4nstA |
Crystal structure of human cdk12/cyclin k in complex with adp-aluminum fluoride |
81
|
298
|
4nj3A |
Modulating the interaction between cdk2 and cyclin a with a quinoline-based inhibitor |
77
|
298
|
4lynA |
Crystal structure of cyclin-dependent kinase 2 (cdk2-wt) complex with (2s)-n-(5-(((5-tert-butyl-1,3-oxazol-2-yl)methyl)sulfanyl)-1,3-thiazol-2-yl)-2-phenylpropanamide |
85
|
298
|
4kd1A |
Cdk2 in complex with dinaciclib |
90
|
300
|
4krdA |
Crystal structure of pho85-pcl10 complex |
87
|
301
|
4krcA |
Crystal structure of pho85-pcl10-atp-gamma-s complex |
91
|
296
|
4i3zA |
Structure of pcdk2/cyclina bound to adp and 2 magnesium ions |
90
|
323
|
4imyA |
The aff4 scaffold binds human p-tefb adjacent to hiv tat |
92
|
296
|
4ii5A |
Structure of pcdk2/cyclina bound to adp and 1 magnesium ion |
89
|
304
|
4gcjA |
Cdk2 in complex with inhibitor rc-3-89 |
99
|
362
|
4g6lA |
Crystal structure of human cdk8/cycc in the dmg-in conformation |
80
|
298
|
4fx3A |
Crystal structure of the cdk2/cyclin a complex with oxindole inhibitor |
77
|
296
|
4fksA |
Crystal structure of the cdk2 in complex with oxindole inhibitor |
82
|
298
|
4fkgA |
Crystal structure of the cdk2 in complex with aminopyrazole inhibitor |
84
|
298
|
3r1yA |
Cdk2 in complex with inhibitor kvr-1-134 |