|
133
|
318
|
3g3nA |
Pde7a catalytic domain in complex with 3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3h)-one |
|
137
|
335
|
3frgA |
Catalytic domain of human phosphodiesterase 4b2b in complex with a quinoline inhibitor |
|
139
|
331
|
3g4iA |
Crystal structure of human phosphodiesterase 4d with d155871 |
|
141
|
330
|
3g4kA |
Crystal structure of human phosphodiesterase 4d with rolipram |
|
136
|
338
|
3ecmA |
Crystal structure of the unliganded pde8a catalytic domain |
|
135
|
338
|
3ecnA |
Crystal structure of pde8a catalytic domain in complex with ibmx |
|
133
|
328
|
3dylA |
Human phosphdiesterase 9 substrate complex (es complex) |
|
131
|
328
|
3dyqA |
Human phosphodiestrase 9 (inhibited by omitting divalent cation) in complex with cgmp |
|
129
|
328
|
3dy8A |
Human phosphodiesterase 9 in complex with product 5'-gmp (e+p complex) |
|
131
|
324
|
3dysA |
Human phosphodiestrase-5'gmp complex (ep), produced by soaking with 20mm cgmp+20 mm mncl2+20 mm mgcl2 for 2 hours, and flash-cooled to liquid nitrogen temperature when substrate was still abudant. |
|
132
|
328
|
3dynA |
Human phosphodiestrase 9 in complex with cgmp (zn inhibited) |
|
139
|
336
|
3d3pA |
Crystal structure of pde4b catalytic domain in complex with a pyrazolopyridine inhibitor |
|
127
|
326
|
3bjcA |
Crystal structure of the pde5a catalytic domain in complex with a novel inhibitor |
|
117
|
330
|
3b2rA |
Crystal structure of pde5a1 catalytic domain in complex with vardenafil |
|
128
|
326
|
2yy2A |
Crystal structure of the human phosphodiesterase 9a catalytic domain complexed with ibmx |
|
128
|
314
|
2y0jA |
Triazoloquinazolines as a novel class of phosphodiesterase 10a (pde10a) inhibitors, part 2, lead-optimisation. |
|
128
|
324
|
2weyA |
Human pde-papaverine complex obtained by ligand soaking of cross- linked protein crystals |
|
141
|
335
|
2r8qA |
Structure of lmjpdeb1 in complex with ibmx |
|
141
|
334
|
2qykA |
Crystal structure of pde4a10 in complex with inhibitor npv |
|
135
|
335
|
2qylA |
Crystal structure of pde4b2b in complex with inhibitor npv |
|
114
|
329
|
2qymA |
Crystal structure of unliganded pde4c2 |
|
140
|
326
|
2qynA |
Crystal structure of pde4d2 in complex with inhibitor npv |
|
135
|
327
|
2pw3A |
Structure of the pde4d-camp complex |
|
137
|
326
|
2ousA |
Crystal structure of pde10a2 mutant d674a |
|
126
|
304
|
2ovvA |
Crystal structure of the catalytic domain of rat phosphodiesterase 10a |
|
132
|
324
|
2ourA |
Crystal structure of pde10a2 mutant d674a in complex with camp |
|
128
|
305
|
2ovyA |
Crystal structure of the catalytic domain of rat phosphodiesterase 10a |
|
125
|
307
|
2o8hA |
Crystal structure of the catalytic domain of rat phosphodiesterase 10a |
|
136
|
330
|
2ouyA |
Crystal structure of pde10a2 mutant d564a in complex with camp. |
|
132
|
326
|
2ouqA |
Crystal structure of pde10a2 in complex with gmp |
|
137
|
329
|
2ouuA |
Crystal structure of pde10a2 mutant d674a in complex with cgmp |
|
132
|
326
|
2hd1A |
Crystal structure of pde9 in complex with ibmx |
|
130
|
326
|
2h44A |
Crystal structure of pde5a1 in complex with icarisid ii |
|
131
|
326
|
2h42A |
Crystal structure of pde5 in complex with sildenafil |
|
122
|
326
|
2h40A |
Crystal structure of the catalytic domain of unliganded pde5 |
|
140
|
334
|
2fm0A |
Crystal structure of pde4d in complex with l-869298 |
|
135
|
334
|
2fm5A |
Crystal structure of pde4d2 in complex with inhibitor l-869299 |
|
133
|
323
|
2chmA |
Crystal structure of n2 substituted pyrazolo pyrimidinones - a flipped binding mode in pde5 |
|
141
|
317
|
1zklA |
Multiple determinants for inhibitor selectivity of cyclic nucleotide phosphodiesterases |
|
138
|
334
|
1zknA |
Structure of pde4d2-ibmx |
|
136
|
340
|
1z1lA |
The crystal structure of the phosphodiesterase 2a catalytic domain |
|
139
|
326
|
1y2dA |
Catalytic domain of human phosphodiesterase 4d in complex with 1-(4-methoxy-phenyl)-3,5-dimethyl-1h-pyrazole-4-carboxylic acid ethyl ester |
|
140
|
326
|
1y2cA |
Catalytic domain of human phosphodiesterase 4d in complex with 3,5-dimethyl-1-phenyl-1h-pyrazole-4-carboxylic acid ethyl ester |
|
134
|
326
|
1y2eA |
Catalytic domain of human phosphodiesterase 4d in complex with 1-(4-amino-phenyl)-3,5-dimethyl-1h-pyrazole-4-carboxylic acid ethyl ester |
|
138
|
326
|
1y2bA |
Catalytic domain of human phosphodiesterase 4d in complex with 3,5-dimethyl-1h-pyrazole-4-carboxylic acid ethyl ester |
|
124
|
323
|
1y2jA |
Catalytic domain of human phosphodiesterase 4b in complex with 3,5-dimethyl-1-(3-nitro-phenyl)-1h-pyrazole-4-carboxylic acid ethyl ester |
|
121
|
323
|
1y2hA |
Catalytic domain of human phosphodiesterase 4b in complex with 1-(2-chloro-phenyl)-3,5-dimethyl-1h-pyrazole-4-carboxylic acid ethyl ester |
|
140
|
326
|
1y2kA |
Catalytic domain of human phosphodiesterase 4d in complex with 3,5-dimethyl-1-(3-nitro-phenyl)-1h-pyrazole-4-carboxylic acid ethyl ester |
|
139
|
326
|
1xonA |
Catalytic domain of human phosphodiesterase 4d in complex with piclamilast |
|
136
|
324
|
1xorA |
Catalytic domain of human phosphodiesterase 4d in complex with zardaverine |
