|
114
|
350
|
5bveA |
Tetrahydropyrrolo-diazepenones as inhibitors of erk2 kinase |
|
115
|
347
|
5hd7A |
Dissecting therapeutic resistance to erk inhibition rat mutant sch772984 in complex with (3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamide |
|
107
|
351
|
4zxtA |
Complex of erk2 with catechol |
|
108
|
345
|
4zzmA |
Human erk2 in complex with an irreversible inhibitor |
|
107
|
356
|
5awmA |
The crystal structure of jnk from drosophila melanogaster reveals an evolutionarily conserved topology with that of mammalian jnk proteins. |
|
71
|
349
|
5ax3A |
Crystal structure of erk2 complexed with allosteric and atp-competitive inhibitors. |
|
115
|
350
|
4zthA |
Structure of human p38amapk-arylpyridazinylpyridine fragment complex used in inhibitor discovery |
|
120
|
344
|
4zsjA |
Mitogen activated protein kinase 7 in complex with inhibitor |
|
110
|
350
|
5etfA |
Structure of dead kinase mapk14 with bound the kim domain of mkk6 |
|
112
|
356
|
4z9lA |
The structure of jnk3 in complex with an imidazole-pyrimidine inhibitor |
|
110
|
355
|
5etiA |
Structure of dead kinase mapk14 |
|
121
|
347
|
4zsgA |
Mitogen activated protein kinase 7 in complex with inhibitor |
|
116
|
341
|
4zslA |
Mitogen activated protein kinase 7 in complex with inhibitor |
|
89
|
351
|
5etaA |
Structure of mapk14 with bound the kim domain of the toxoplasma protein gra24 |
|
103
|
350
|
5ekoA |
Crystal structure of mapk13 complex with inhibitor |
|
103
|
355
|
5etcA |
Structure of inactive mapk14 with ordered activation loop |
|
105
|
350
|
4ynoA |
Crystal structure of mapk13 at inactive form |
|
98
|
362
|
5ci6A |
Crystal structure of arabidopsis thaliana mpk6 |
|
100
|
356
|
4y5hA |
Pyridopyrimidinone derivatives as potent and selective c-jun n-terminal kinase (jnk) inhibitors |
|
109
|
346
|
4xrjA |
Crystal structure of erk2 in complex with an inhibitor |
|
111
|
347
|
4xp0A |
Crystal structure of erk2 in complex with an inhibitor |
|
102
|
345
|
4xoyA |
Crystal structure of erk2 in complex with an inhibitor |
|
104
|
349
|
4xj0A |
Crystal structure of erk2 in complex with an inhibitor 14k |
|
113
|
345
|
4xrlA |
Crystal structure at room temperature of erk2 in complex with an inhibitor |
|
114
|
347
|
4xozA |
Crystal structure of erk2 in complex with an inhibitor |
|
111
|
347
|
4xp3A |
Crystal structure of erk2 in complex with an inhibitor |
|
108
|
346
|
4xp2A |
Crystal structure of erk2 in complex with an inhibitor |
|
107
|
346
|
4xneA |
Crystal structure of erk2 in complex with an inhibitor |
|
99
|
356
|
4y46A |
Pyridopyrimidinone derivatives as potent and selective c-jun n-terminal kinase (jnk) inhibitors |
|
108
|
356
|
4whzA |
Design and synthesis of highly potent and isoform selective jnk3 inhibitors: sar studies on aminopyrazole derivatives |
|
102
|
356
|
4w4yA |
Jnk2/3 in complex with 3-(4-{[(4-methylphenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-n-(2-methylpyridin-4-yl)benzamide |
|
101
|
356
|
4w4xA |
Jnk2/3 in complex with 3-(4-{[(4-fluorophenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-n-(2-methylpyridin-4-yl)benzamide |
|
103
|
356
|
4w4vA |
Jnk2/3 in complex with 3-(4-{[(2-chlorophenyl)carbamoyl]amino}-1h-pyrazol-1-yl)-n-(2-methylpyridin-4-yl)benzamide |
|
108
|
355
|
4x21A |
The map kinase jnk3 as target for halogen bonding |
|
111
|
356
|
4w4wA |
Jnk2/3 in complex with n-(2-methylpyridin-4-yl)-3-{4-[(phenylcarbamoyl)amino]-1h-pyrazol-1-yl}benzamide |
|
104
|
351
|
4s34A |
Erk2 (i84a) in complex with amp-pnp |
|
104
|
352
|
4s30A |
Erk2 intrinsically active mutant (i84a) |
|
106
|
357
|
4u79A |
Crystal structure of human jnk3 in complex with a benzenesulfonamide inhibitor. |
|
111
|
351
|
4s2zA |
Erk2 intrinsically active mutant r65s |
|
94
|
348
|
4tyhB |
Ternary complex of p38 and mk2 with a p38 inhibitor |
|
114
|
352
|
4s31A |
Crystal structure of mitogen-activated protein kinase 1 wterk2 at 1.45a |
|
111
|
351
|
4s32A |
Crystal structure of erk2 amp-pnp complex |
|
112
|
352
|
4s33A |
Erk2 r65s mutant complexed with amp-pnp |
|
108
|
341
|
4qyyA |
Discovery of novel, dual mechanism erk inhibitors by affinity selection screening of an inactive kinase state |
|
103
|
349
|
4qp1A |
Crystal structure of erk2 in complex with n-cyclohexyl-9h-purin-6-amine |
|
107
|
345
|
4qp7A |
Crystal structure of erk2 in complex with 2-(1h-pyrazol-4-yl)-5h-pyrrolo[2,3-b]pyrazine |
|
123
|
358
|
4qtdA |
Structure of human jnk1 in complex with sch772984 and the amppnp-hydrolysed triphosphate revealing the second type-i binding mode |
|
108
|
345
|
4qp4A |
Crystal structure of erk2 in complex with n-cyclohexyl-9h-purin-6-amine |
|
110
|
345
|
4qp9A |
Crystal structure of erk2 in complex with 7-(1-propyl-1h-pyrazol-4-yl)-2-(pyridin-4-yl)-5h-pyrrolo[2,3-b]pyrazine |
|
111
|
349
|
4qtaA |
Structure of human erk2 in complex with sch772984 revealing a novel inhibitor-induced binding pocket |
