|
99
|
385
|
2vizA |
Human bace-1 in complex with n-((1s,2r)-3-(((1s)-2-(cyclohexylamino)- 1-methyl-2-oxoethyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-3-(2-oxo- 1-pyrrolidinyl)-5-(propyloxy)benzamide |
|
100
|
385
|
2vnmA |
Human bace-1 in complex with 3-(1,1-dioxidotetrahydro-2h-1,2-thiazin- 2-yl)-5-(ethylamino)-n-((1s,2r)-2-hydroxy-1-(phenylmethyl)-3-(((3-(trifluoromethyl)phenyl)methyl)amino)propyl)benzamide |
|
99
|
385
|
2viyA |
Human bace-1 in complex with n-((1s,2r)-3-(((1s)-2-(cyclohexylamino)- 1-methyl-2-oxoethyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-3-(pentylsulfonyl)benzamide |
|
85
|
387
|
2va6A |
X-ray crystal structure of beta secretase complexed with compound 24 |
|
101
|
385
|
2vijA |
Human bace-1 in complex with 3-(1,1-dioxidotetrahydro-2h-1,2-thiazin- 2-yl)-5-(ethylamino)-n-((1s,2r)-2-hydroxy-1-(phenylmethyl)-3-(1,2,3,4- tetrahydro-1-naphthalenylamino)propyl)benzamide |
|
89
|
387
|
2va5A |
X-ray crystal structure of beta secretase complexed with compound 8c |
|
100
|
389
|
2vj9A |
Human bace-1 in complex with n-((1s,2r)-3-(cyclohexylamino)-2-hydroxy- 1-(phenylmethyl)propyl)-3-(ethylamino)-5-(2-oxo-1-pyrrolidinyl) benzamide |
|
94
|
387
|
2va7A |
X-ray crystal structure of beta secretase complexed with compound 27 |
|
98
|
385
|
2vj7A |
Human bace-1 in complex with 3-(ethylamino)-n-((1s,2r)-2-hydroxy-1-(phenylmethyl)-3-(((3-(trifluoromethyl)phenyl)methyl)amino)propyl)-5-(2-oxo-1-pyrrolidinyl)benzamide |
|
100
|
385
|
2vj6A |
Human bace-1 in complex with n-((1s,2r)-3-(((1s)-2-(cyclohexylamino)- 1-methyl-2-oxoethyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-3-(ethylamino)-5-(2-oxo-1-pyrrolidinyl)benzamide |
|
97
|
388
|
2qzkA |
Crystal structure of human beta secretase complexed with i21 |
|
91
|
386
|
2qu2A |
Bace1 with compound 1 |
|
97
|
390
|
2qzlA |
Crystal structure of human beta secretase complexed with ixs |
|
106
|
390
|
2qmgA |
Structure of bace bound to sch745966 |
|
102
|
395
|
2qk5A |
Structure of bace1 bound to sch626485 |
|
106
|
390
|
2qp8A |
Structure of bace bound to sch734723 |
|
86
|
385
|
2q15A |
Structure of bace complexed to compound 3a |
|
91
|
385
|
2qu3A |
Bace1 with compound 2 |
|
107
|
390
|
2qmfA |
Structure of bace bound to sch735310 |
|
106
|
390
|
2qmdA |
Structure of bace bound to sch722924 |
|
96
|
388
|
2q11A |
Structure of bace complexed to compound 1 |
|
98
|
389
|
2ph8A |
Crystal structure of human beta secretase complexed with inhibitor |
|
95
|
389
|
2ph6A |
Crystal structure of human beta secretase complexed with inhibitor |
|
101
|
389
|
2p4jA |
Crystal structure of beta-secretase bond to an inhibitor with isophthalamide derivatives at p2-p3 |
|
98
|
391
|
2p8hA |
Crystal structure of human beta secretase complexed with inhibitor |
|
98
|
388
|
2p83A |
Potent and selective isophthalamide s2 hydroxyethylamine inhibitor of bace1 |
|
90
|
387
|
2ohuA |
X-ray crystal structure of beta secretase complexed with compound 8b |
|
99
|
387
|
2ohrA |
X-ray crystal structure of beta secretase complexed with compound 6a |
|
92
|
387
|
2ohkA |
X-ray crystal structure of beta secretase complexed with 1-amino-isoquinoline |
|
93
|
387
|
2ohmA |
X-ray crystal structure of beta secretase complexed with n~3~-benzylpyridine-2,3-diamine |
|
90
|
387
|
2ohnA |
X-ray crystal structure of beta secretase complexed with 4-(4-fluorobenzyl)piperidine |
|
99
|
391
|
2oahA |
Crystal structure of human beta secretase complexed with inhibitor |
|
95
|
387
|
2ohsA |
X-ray crystal structure of beta secretase complexed with compound 6b |
|
87
|
387
|
2ohtA |
X-ray crystal structure of beta secretase complexed with compound 7 |
|
90
|
387
|
2ohlA |
X-ray crystal structure of beta secretase complexed with 2-aminoquinoline |
|
91
|
387
|
2ohpA |
X-ray crystal structure of beta secretase complexed with compound 3 |
|
90
|
387
|
2of0A |
X-ray crystal structure of beta secretase complexed with compound 5 |
|
89
|
387
|
2ohqA |
X-ray crystal structure of beta secretase complexed with compound 4 |
|
101
|
391
|
2ntrA |
Crystal structure of human bace-1 bound to inhibitor |
|
101
|
389
|
2iqgA |
Crystal structure of hydroxyethyl secondary amine-based peptidomimetic inhibitor of human beta-secretase (bace) |
|
93
|
391
|
2irzA |
Crystal structure of human beta-secretase complexed with inhibitor |
|
95
|
391
|
2is0A |
Crystal structure of human beta-secretase complexed with inhibitor |
|
101
|
389
|
2hm1A |
Crystal structure of human beta-secretase (bace) in the presence of an inhibitor (2) |
|
100
|
388
|
2hizA |
Crystal structure of human beta-secretase (bace) in the presence of an inhibitor |
|
104
|
389
|
2g94A |
Crystal structure of beta-secretase bound to a potent and highly selective inhibitor. |
|
89
|
388
|
2fdpA |
Crystal structure of beta-secretase complexed with an amino-ethylene inhibitor |
|
98
|
388
|
2f3eA |
Crystal structure of the bace complex with axq093, a macrocyclic inhibitor |
|
97
|
388
|
2f3fA |
Crystal structure of the bace complex with bdf488, a macrocyclic inhibitor |
|
96
|
391
|
2b8lA |
Crystal structure of human beta secretase complexed with inhibitor |
|
92
|
391
|
2b8vA |
Crystal structure of human beta-secretase complexed with l-l000430,469 |
