41
|
130
|
5ieaA |
Trim5 b-box2 and coiled-coil chimera |
72
|
238
|
5hvqC |
Alternative model of the mage-g1 nse-1 complex |
27
|
86
|
5hmkA |
Hdm2 in complex with a 3,3-disubstituted piperidine |
107
|
303
|
5hkyA |
Crystal structure of c-cbl tkbd domain in complex with spry2 peptide (36-60, py55) refined to 1.8a resolution (p6 form) |
51
|
180
|
5h1uA |
Complex structure of trim24 phd-bromodomain and inhibitor 2 |
31
|
95
|
5hmhA |
Hdm2 in complex with a 3,3-disubstituted piperidine |
50
|
182
|
5h1tA |
Complex structure of trim24 phd-bromodomain and inhibitor 1 |
16
|
79
|
5ferA |
Complex of trim25 ring with ubch5-ub |
30
|
106
|
6h6qA |
Fragment derived xiap inhibitor |
33
|
107
|
6h6rA |
Fragment derived xiap inhibitor |
30
|
94
|
6ggnA |
In vitro and in vivo characterization of a novel, highly potent p53-mdm2 inhibitor |
57
|
214
|
6g2iH |
Filament of acetyl-coa carboxylase and brct domains of brca1 (acc-brct) at 5.9 a resolution |
89
|
391
|
6fptA |
Crystal structure of danio rerio lin41 filamin-nhl domains |
110
|
441
|
6flnA |
Crystal structure of the human trim25 coiled-coil and pryspry domains |
50
|
198
|
6flmA |
Crystal structure of the human trim25 pryspry domain |
24
|
98
|
6exwA |
Crystal structure of ciap1-bir3 in complex with a covalently bound sm |
28
|
99
|
6ey2A |
Crystal structure of xiap-bir3 in complex with a ciap1-selective sm |
76
|
342
|
6cvzA |
Crystal structure of the wd40-repeat of rfwd3 |
0
|
12
|
6cf6C |
Rnf146 tbm-tankyrase arc2-3 complex |
29
|
150
|
6b9mA |
Crystal structure of uhrf1 ttd domain in complex with the polybasic region |
0
|
17
|
6b9mD |
Crystal structure of uhrf1 ttd domain in complex with the polybasic region |
23
|
87
|
5ywrB |
Crystal structure of ring e3 ligase znrf1 in complex with ube2n (ubc13) |
27
|
87
|
5zxfA |
The 1.25a crystal structure of his6-tagged mdm2 in complex with nutlin-3a |
35
|
81
|
5ydkA |
Crystal structure of rnf168 udm1 in complex with lys63-linked diubiquitin, tetrameric form |
0
|
8
|
5ycoE |
Complex structure of pcna with uhrf2 |
35
|
95
|
5xxkA |
Structure-activity studies of mdm2/mdm4-binding stapled peptides comprising non-natural amino acids |
0
|
12
|
5y21C |
Crystal structure of al2 pal domain in complex with atring1a proximal site |
36
|
79
|
5xisA |
Crystal structure of rnf168 udm1 in complex with lys63-linked diubiquitin, form i |
6
|
43
|
5vf0B |
Solution nmr structure of human rad18 (198-240) in complex with ubiquitin |
20
|
77
|
5vzvA |
Trim23 ring domain |
28
|
85
|
5vk0A |
Crystal structure of human mdm2 in complex with a 12-mer lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor pmi |
24
|
104
|
5vo0A |
Structure of a traf6-ubc13~ub complex |
20
|
108
|
5vnzA |
Structure of a traf6-ubc13~ub complex |
30
|
106
|
5c7aA |
Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 7 |
49
|
134
|
5f7tE |
Trim5 b-box2 and coiled-coil chimera |
32
|
106
|
5c3kA |
Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 4 |
31
|
107
|
5c7cA |
Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 18 |
32
|
107
|
5c83A |
Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 21 |
33
|
106
|
5c3hA |
Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 1 |
32
|
106
|
5c7bA |
Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 5 |
35
|
106
|
5c7dA |
Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 17 |
33
|
106
|
5c0lA |
Fragment-based drug discovery targeting inhibitor of apoptosis proteins: compound 2 |
27
|
84
|
4zycA |
Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53-mdm2 interaction with a distinct binding mode: hdm2 (mdm2) complexed with cpd5 |
29
|
83
|
5afgA |
Structure of the stapled peptide bound to mdm2 |
34
|
94
|
4zgkA |
Structure of mdm2 with low molecular weight inhibitor. |
31
|
95
|
4zfiA |
Structure of mdm2 with low molecular weight inhibitor |
30
|
91
|
4zyiA |
Discovery of nvp-cgm097 - a highly potent and selective mdm2 inhibitor undergoing phase 1 clinical trials in p53wt tumors: hdm2 (mdm2) complexed with cpd2 |
31
|
93
|
4zyfA |
Discovery of nvp-cgm097 - a highly potent and selective mdm2 inhibitor undergoing phase 1 clinical trials in p53wt tumors: hdm2 (mdm2) complexed with nvp-cgm097 |
54
|
155
|
4zlcA |
Crystal structure of the roq domain of human roquin-2 |
52
|
183
|
4ybmA |
Crystal structure of trim24 phd-bromodomain complexed with n-{6-[3-(benzyloxy)phenoxy]-1,3-dimethyl-2-oxo-2,3-dihydro-1h-1,3-benzodiazol-5-yl}-3,4-dimethoxybenzene-1-sulfonamide (7b) |