|
91
|
310
|
4dceA |
Crystal structure of human anaplastic lymphoma kinase in complex with a piperidine-carboxamide inhibitor |
|
95
|
302
|
4d2rA |
Human igf in complex with a dyrk1b inhibitor |
|
75
|
272
|
4cqeA |
B-raf kinase v600e mutant in complex with a diarylthiazole b-raf inhibitor |
|
79
|
272
|
4d4sA |
Focal adhesion kinase catalytic domain |
|
83
|
274
|
4dfnA |
Crystal structure of spleen tyrosine kinase complexed with an adamantylpyrazine inhibitor |
|
82
|
272
|
4d4vA |
Focal adhesion kinase catalytic domain |
|
74
|
274
|
4dbnA |
Crystal structure of the kinase domain of human b-raf with a [1,3]thiazolo[5,4-b]pyridine derivative |
|
98
|
308
|
4cd0A |
Structure of l1196m mutant human anaplastic lymphoma kinase in complex with 2-(5-(6-amino-5-((r)-1-(5-fluoro-2-(2h-1,2,3-triazol-2- yl)phenyl)ethoxy)pyridin-3-yl)-4-methylthiazol-2-yl)propane-1,2-diol |
|
81
|
271
|
4c7tA |
Focal adhesion kinase catalytic domain in complex with a diarylamino- 1,3,5-triazine inhibitor |
|
107
|
322
|
4c02A |
Crystal structure of human acvr1 (alk2) in complex with fkbp12.6 and dorsomorphin |
|
94
|
308
|
4cnhA |
Structure of the human anaplastic lymphoma kinase in complex with the inhibitor 3-((1r)-1-(5-fluoro-2-methoxyphenyl)ethoxy)-5-(1-methyl-1h- 1,2,3-triazol-5-yl)pyridin-2-amine |
|
87
|
309
|
4c8bA |
Structure of the kinase domain of human ripk2 in complex with ponatinib |
|
145
|
454
|
4btfA |
Structure of mlkl |
|
95
|
308
|
4cmtA |
Structure of the human anaplastic lymphoma kinase in complex with the inhibitor 3-((1r)-1-(5-fluoro-2-(2h-1,2,3-triazol-2-yl)phenyl)ethoxy)- 5-(3-(methylsulfonyl)phenyl)pyridin-2-amine |
|
83
|
261
|
4c3fA |
Structure of lck in complex with a compound discovered by virtual fragment linking |
|
96
|
309
|
4cmoA |
Structure of the human anaplastic lymphoma kinase in complex with the inhibitor 2-((1r)-1-((3-amino-6-(2-methoxypyridin-3-yl)pyrazin-2-yl) oxy)ethyl)-4-fluoro-n-methylbenzamide |
|
95
|
314
|
4ckiA |
Crystal structure of oncogenic ret tyrosine kinase m918t bound to adenosine |
|
89
|
287
|
4c61A |
Inhibitors of jak2 kinase domain |
|
81
|
272
|
4brxA |
Focal adhesion kinase catalytic domain in complex with a diarylamino- 1,3,5-triazine inhibitor |
|
93
|
308
|
4ccbA |
Structure of the human anaplastic lymphoma kinase in complex with 3-((r)-1-(5-fluoro-2-(2h-1,2,3-triazol-2-yl)phenyl)ethoxy)-5-(5-methyl-1h- pyrazol-4-yl)pyridin-2-amine |
|
96
|
309
|
4ccuA |
Structure of the human anaplastic lymphoma kinase in complex with 2-(5-(6-amino-5-((r)-1-(5-fluoro-2-(2h-1,2,3-triazol-2-yl)phenyl)ethoxy) pyridin-3-yl)-4-methylthiazol-2-yl)propan-2-ol |
|
89
|
287
|
4c62A |
Inhibitors of jak2 kinase domain |
|
96
|
308
|
4cmuA |
Structure of the human anaplastic lymphoma kinase in complex with the inhibitor (10r)-7-amino-12-fluoro-1,3,10,16-tetramethyl-16,17-dihydro- 1h-8,4-(metheno)pyrazolo(4,3-h)(2,5,11)benzoxadiazacyclotetradecin-15(10h)-one |
|
98
|
308
|
4cliA |
Structure of the human anaplastic lymphoma kinase in complex with pf- 06463922 ((10r)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16, 17-tetrahydro-2h-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecine-3-carbonitrile). |
|
96
|
291
|
4aqcA |
Triazolopyridine-based inhibitor of janus kinase 2 |
|
83
|
288
|
4bbeA |
Aminoalkylpyrimidine inhibitor complexes with jak2 |
|
97
|
299
|
4at4A |
Crystal structure of trkb kinase domain in complex with ex429 |
|
91
|
288
|
4bbfA |
Aminoalkylpyrimidine inhibitor complexes with jak2 |
|
102
|
312
|
4asdA |
Crystal structure of vegfr2 (juxtamembrane and kinase domains) in complex with sorafenib (bay 43-9006) |
|
96
|
314
|
4bkjA |
Crystal structure of the human ddr1 kinase domain in complex with imatinib |
|
76
|
282
|
4aw5A |
Complex of the ephb4 kinase domain with an oxindole inhibitor |
|
79
|
283
|
4bb4A |
Ephb4 kinase domain inhibitor complex |
|
91
|
296
|
4bggA |
Crystal structure of the acvr1 kinase in complex with ldn-213844 |
|
95
|
299
|
4aszA |
Crystal structure of apo trkb kinase domain |
|
97
|
299
|
4at3A |
Crystal structure of trkb kinase domain in complex with cpd5n |
|
99
|
299
|
4at5A |
Crystal structure of trkb kinase domain in complex with gw2580 |
|
95
|
293
|
3zxzA |
X-ray structure of pf-04217903 bound to the kinase domain of c-met |
|
89
|
317
|
4agdA |
Crystal structure of vegfr2 (juxtamembrane and kinase domains) in complex with sunitinib (su11248) (n-2-diethylaminoethyl)-5-((z)-(5- fluoro-2-oxo-1h-indol-3-ylidene)methyl)-2,4-dimethyl-1h-pyrrole-3- carboxamide) |
|
93
|
286
|
3zzeA |
Crystal structure of c-met kinase domain in complex with n'-((3z)-4- chloro-7-methyl-2-oxo-1,2-dihydro-3h-indol-3-ylidene)-2-(4- hydroxyphenyl)propanohydrazide |
|
78
|
277
|
4agwA |
Discovery of a small molecule type ii inhibitor of wild-type and gatekeeper mutants of bcr-abl, pdgfralpha, kit, and src kinases |
|
96
|
308
|
4anlA |
Structure of g1269a mutant anaplastic lymphoma kinase |
|
84
|
290
|
4aojA |
Human trka in complex with the inhibitor az-23 |
|
100
|
303
|
4ag8A |
Crystal structure of the vegfr2 kinase domain in complex with axitinib (ag-013736) (n-methyl-2-(3-((e)-2-pyridin-2-yl-vinyl)-1h- indazol-6-ylsulfanyl)-benzamide) |
|
98
|
312
|
3zosA |
Structure of the ddr1 kinase domain in complex with ponatinib |
|
98
|
309
|
4anqA |
Structure of g1269a mutant anaplastic lymphoma kinase in complex with crizotinib |
|
103
|
312
|
4aseA |
Crystal structure of vegfr2 (juxtamembrane and kinase domains) in complex with tivozanib (av-951) |
|
91
|
293
|
4aoiA |
Crystal structure of c-met kinase domain in complex with 4-(3-((1h- pyrrolo(2,3-b)pyridin-3-yl)methyl)-(1,2,4)triazolo(4,3-b)(1,2,4) triazin-6-yl)benzonitrile |
|
86
|
294
|
3zonA |
Human tyk2 pseudokinase domain bound to a kinase inhibitor |
|
91
|
293
|
4ap7A |
Crystal structure of c-met kinase domain in complex with 4-((6-(4- fluorophenyl)-(1,2,4)triazolo(4,3-b)(1,2,4)triazin-3-yl)methyl)phenol |
|
100
|
318
|
4agcA |
Crystal structure of vegfr2 (juxtamembrane and kinase domains) in complex with axitinib (ag-013736) (n-methyl-2-(3-((e)-2-pyridin-2-yl- vinyl)-1h-indazol-6-ylsulfanyl)-benzamide) |
