1AP8A

Translation initiation factor eif4e in complex with m7gdp, nmr, 20 structures
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
213
structure length
213
Chain Sequence
MSVEEVSKKFEENVSVDDTTATPKTVLSDSAHFDVKHPLNTKWTLWYTKPAVDKSESWSDLLRPVTSFQTVEEFWAIIQNIPEPHELPLKSDYHVFRNDVRPEWEDEANAKGGKWSFQLRGKGADIDELWLRTLLAVIGETIDEDDSQINGVVLSIRKGGNKFALWTKSEDKEPLLRIGGKFKQVLKLTDDGHLEFFPHSSANGRHPQPSITL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of translation factor eIF4E bound to m7GDP and interaction with 4E-binding protein.
pubmed doi rcsb
molecule tags Rna cap
source organism Saccharomyces cerevisiae
molecule keywords TRANSLATION INITIATION FACTOR EIF4E
total genus 28
structure length 213
sequence length 213
ec nomenclature
pdb deposition date 1997-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01652 IF4E Eukaryotic initiation factor 4E
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.760.10 Alpha Beta 2-Layer Sandwich RNA Cap, Translation Initiation Factor Eif4e RNA Cap, Translation Initiation Factor Eif4e 1ap8A00
5T46A 2IDRA 4UEDA 5T48A 1AP8A 1ZTPA 2WMCA 4UEAA 1EJ1A 2W97B 3HXIA 4TPWA 4AZAA 4UE8A 1RF8A 1WKWA 3AM7A 4AXGA 5T47A 1IPBA 1EJHA 5EHCA 4B6UA 4UEBA 4UECA 4B6VA 5ABVA 5EKVA 5GW6A 2V8WA 5ABUA 5EI3A 2W97A 2JGBA 4UE9A 2JGCA 5EIRA 1EJ4A 3HXGA 4BEAA 2V8YA 5ABXA 4DUMA 5ABYA 4TQBA 1IPCA 3TF2A 3U7XA 4TQCA 3M94A 1L8BA 2Q4KA 5BXVA 2GPQA 3M93A 4DT6A 2V8XA 2IDVA
chains in the Genus database with same CATH superfamily
5T46A 2IDRA 4UEDA 5T48A 1AP8A 1ZTPA 2WMCA 4UEAA 1EJ1A 2W97B 3HXIA 4TPWA 4AZAA 4UE8A 1RF8A 1WKWA 3AM7A 4AXGA 5T47A 1IPBA 1EJHA 5EHCA 4B6UA 4UEBA 4UECA 4B6VA 5ABVA 5EKVA 5GW6A 2V8WA 5ABUA 5EI3A 2W97A 2JGBA 4UE9A 2JGCA 5EIRA 1EJ4A 3HXGA 4BEAA 2V8YA 5ABXA 4DUMA 5ABYA 4TQBA 1IPCA 3TF2A 3U7XA 4TQCA 3M94A 1L8BA 2Q4KA 5BXVA 2GPQA 3M93A 4DT6A 2V8XA 2IDVA
chains in the Genus database with same CATH topology
5T46A 2IDRA 4UEDA 5T48A 1AP8A 1ZTPA 2WMCA 4UEAA 1EJ1A 2W97B 3HXIA 4TPWA 4AZAA 4UE8A 1RF8A 1WKWA 3AM7A 4AXGA 5T47A 1IPBA 1EJHA 5EHCA 4B6UA 4UEBA 4UECA 4B6VA 5ABVA 5EKVA 5GW6A 2V8WA 5ABUA 5EI3A 2W97A 2JGBA 4UE9A 2JGCA 5EIRA 1EJ4A 3HXGA 4BEAA 2V8YA 5ABXA 4DUMA 5ABYA 4TQBA 1IPCA 3TF2A 3U7XA 4TQCA 3M94A 1L8BA 2Q4KA 5BXVA 2GPQA 3M93A 4DT6A 2V8XA 2IDVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5T46 A;  2IDR A;  4UED A;  5T48 A;  1AP8 A;  1ZTP A;  2WMC A;  4UEA A;  1EJ1 A;  2W97 B;  3HXI A;  4TPW A;  4AZA A;  4UE8 A;  1RF8 A;  1WKW A;  3AM7 A;  4AXG A;  5T47 A;  1IPB A;  1EJH A;  5EHC A;  4B6U A;  4UEB A;  4UEC A;  4B6V A;  5ABV A;  5EKV A;  5GW6 A;  2V8W A;  5ABU A;  5EI3 A;  2W97 A;  2JGB A;  4UE9 A;  2JGC A;  5EIR A;  1EJ4 A;  3HXG A;  4BEA A;  2V8Y A;  5ABX A;  4DUM A;  5ABY A;  4TQB A;  1IPC A;  3TF2 A;  3U7X A;  4TQC A;  3M94 A;  1L8B A;  2Q4K A;  5BXV A;  2GPQ A;  3M93 A;  4DT6 A;  2V8X A;  2IDV A; 
#chains in the Genus database with same CATH topology
 5T46 A;  2IDR A;  4UED A;  5T48 A;  1AP8 A;  1ZTP A;  2WMC A;  4UEA A;  1EJ1 A;  2W97 B;  3HXI A;  4TPW A;  4AZA A;  4UE8 A;  1RF8 A;  1WKW A;  3AM7 A;  4AXG A;  5T47 A;  1IPB A;  1EJH A;  5EHC A;  4B6U A;  4UEB A;  4UEC A;  4B6V A;  5ABV A;  5EKV A;  5GW6 A;  2V8W A;  5ABU A;  5EI3 A;  2W97 A;  2JGB A;  4UE9 A;  2JGC A;  5EIR A;  1EJ4 A;  3HXG A;  4BEA A;  2V8Y A;  5ABX A;  4DUM A;  5ABY A;  4TQB A;  1IPC A;  3TF2 A;  3U7X A;  4TQC A;  3M94 A;  1L8B A;  2Q4K A;  5BXV A;  2GPQ A;  3M93 A;  4DT6 A;  2V8X A;  2IDV A; 
#chains in the Genus database with same CATH homology
 5T46 A;  2IDR A;  4UED A;  5T48 A;  1AP8 A;  1ZTP A;  2WMC A;  4UEA A;  1EJ1 A;  2W97 B;  3HXI A;  4TPW A;  4AZA A;  4UE8 A;  1RF8 A;  1WKW A;  3AM7 A;  4AXG A;  5T47 A;  1IPB A;  1EJH A;  5EHC A;  4B6U A;  4UEB A;  4UEC A;  4B6V A;  5ABV A;  5EKV A;  5GW6 A;  2V8W A;  5ABU A;  5EI3 A;  2W97 A;  2JGB A;  4UE9 A;  2JGC A;  5EIR A;  1EJ4 A;  3HXG A;  4BEA A;  2V8Y A;  5ABX A;  4DUM A;  5ABY A;  4TQB A;  1IPC A;  3TF2 A;  3U7X A;  4TQC A;  3M94 A;  1L8B A;  2Q4K A;  5BXV A;  2GPQ A;  3M93 A;  4DT6 A;  2V8X A;  2IDV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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