1E0FI

Crystal structure of the human alpha-thrombin-haemadin complex: an exosite ii-binding inhibitor
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
57
structure length
57
Chain Sequence
IRFGMGKVPCPDGEVGYTCDCGEKICLYGQSCNDGQCSGDPKPSSEFEEFEIDEEEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Human Alpha-Thrombin-Haemadin Complex: An Exosite II-Binding Inhibitor
pubmed doi rcsb
molecule tags Hydrolase
source organism Haemadipsa sylvestris
molecule keywords THROMBIN
total genus 4
structure length 57
sequence length 57
chains with identical sequence J, K
ec nomenclature
pdb deposition date 2000-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF09065 Haemadin Haemadin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.10.10 Mainly Beta Distorted Sandwich Thrombin Inhibitor (Hirudin); Chain I Thrombin Inhibitor (Hirudin), subunit I 1e0fI01
6HIRA 4MLFD 1E0FI 4HIRA 2JOOA 5HIRA 1HICA 2PW8I 1HRTI 4HTCI 2HIRA
chains in the Genus database with same CATH superfamily
6HIRA 4MLFD 1E0FI 4HIRA 2JOOA 5HIRA 1HICA 2PW8I 1HRTI 4HTCI 2HIRA
chains in the Genus database with same CATH topology
6HIRA 4MLFD 1E0FI 4HIRA 2JOOA 5HIRA 1HICA 2PW8I 1HRTI 4HTCI 2HIRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 6HIR A;  4MLF D;  1E0F I;  4HIR A;  2JOO A;  5HIR A;  1HIC A;  2PW8 I;  1HRT I;  4HTC I;  2HIR A; 
#chains in the Genus database with same CATH topology
 6HIR A;  4MLF D;  1E0F I;  4HIR A;  2JOO A;  5HIR A;  1HIC A;  2PW8 I;  1HRT I;  4HTC I;  2HIR A; 
#chains in the Genus database with same CATH homology
 6HIR A;  4MLF D;  1E0F I;  4HIR A;  2JOO A;  5HIR A;  1HIC A;  2PW8 I;  1HRT I;  4HTC I;  2HIR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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