1EJ1A

Cocrystal structure of the messenger rna 5' cap-binding protein (eif4e) bound to 7-methyl-gdp
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
182
structure length
178
Chain Sequence
KHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSKNRFVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cocrystal structure of the messenger RNA 5' cap-binding protein (eIF4E) bound to 7-methyl-GDP.
pubmed doi rcsb
molecule tags Translation
source organism Mus musculus
molecule keywords EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
total genus 57
structure length 178
sequence length 182
chains with identical sequence B
ec nomenclature
pdb deposition date 2000-02-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01652 IF4E Eukaryotic initiation factor 4E
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.760.10 Alpha Beta 2-Layer Sandwich RNA Cap, Translation Initiation Factor Eif4e RNA Cap, Translation Initiation Factor Eif4e 1ej1A00
1IPBA 2V8XA 3HXIA 5EI3A 1IPCA 1L8BA 4TQBA 3U7XA 2IDRA 1ZTPA 3TF2A 2IDVA 1EJHA 2Q4KA 5T47A 2V8YA 5EKVA 4UEAA 3AM7A 3M93A 2W97A 2W97B 5ABUA 2GPQA 4B6VA 4B6UA 2V8WA 4DT6A 5ABVA 5ABXA 4TPWA 4BEAA 4UE8A 4AXGA 5T46A 2JGBA 4AZAA 5GW6A 1EJ1A 5BXVA 4UE9A 1RF8A 5ABYA 3M94A 4TQCA 5EHCA 2JGCA 5EIRA 4UEBA 1WKWA 4UEDA 1EJ4A 3HXGA 2WMCA 4UECA 1AP8A 4DUMA 5T48A
chains in the Genus database with same CATH superfamily
1IPBA 2V8XA 3HXIA 5EI3A 1IPCA 1L8BA 4TQBA 3U7XA 2IDRA 1ZTPA 3TF2A 2IDVA 1EJHA 2Q4KA 5T47A 2V8YA 5EKVA 4UEAA 3AM7A 3M93A 2W97A 2W97B 5ABUA 2GPQA 4B6VA 4B6UA 2V8WA 4DT6A 5ABVA 5ABXA 4TPWA 4BEAA 4UE8A 4AXGA 5T46A 2JGBA 4AZAA 5GW6A 1EJ1A 5BXVA 4UE9A 1RF8A 5ABYA 3M94A 4TQCA 5EHCA 2JGCA 5EIRA 4UEBA 1WKWA 4UEDA 1EJ4A 3HXGA 2WMCA 4UECA 1AP8A 4DUMA 5T48A
chains in the Genus database with same CATH topology
1IPBA 2V8XA 3HXIA 5EI3A 1IPCA 1L8BA 4TQBA 3U7XA 2IDRA 1ZTPA 3TF2A 2IDVA 1EJHA 2Q4KA 5T47A 2V8YA 5EKVA 4UEAA 3AM7A 3M93A 2W97A 2W97B 5ABUA 2GPQA 4B6VA 4B6UA 2V8WA 4DT6A 5ABVA 5ABXA 4TPWA 4BEAA 4UE8A 4AXGA 5T46A 2JGBA 4AZAA 5GW6A 1EJ1A 5BXVA 4UE9A 1RF8A 5ABYA 3M94A 4TQCA 5EHCA 2JGCA 5EIRA 4UEBA 1WKWA 4UEDA 1EJ4A 3HXGA 2WMCA 4UECA 1AP8A 4DUMA 5T48A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IPB A;  2V8X A;  3HXI A;  5EI3 A;  1IPC A;  1L8B A;  4TQB A;  3U7X A;  2IDR A;  1ZTP A;  3TF2 A;  2IDV A;  1EJH A;  2Q4K A;  5T47 A;  2V8Y A;  5EKV A;  4UEA A;  3AM7 A;  3M93 A;  2W97 A;  2W97 B;  5ABU A;  2GPQ A;  4B6V A;  4B6U A;  2V8W A;  4DT6 A;  5ABV A;  5ABX A;  4TPW A;  4BEA A;  4UE8 A;  4AXG A;  5T46 A;  2JGB A;  4AZA A;  5GW6 A;  1EJ1 A;  5BXV A;  4UE9 A;  1RF8 A;  5ABY A;  3M94 A;  4TQC A;  5EHC A;  2JGC A;  5EIR A;  4UEB A;  1WKW A;  4UED A;  1EJ4 A;  3HXG A;  2WMC A;  4UEC A;  1AP8 A;  4DUM A;  5T48 A; 
#chains in the Genus database with same CATH topology
 1IPB A;  2V8X A;  3HXI A;  5EI3 A;  1IPC A;  1L8B A;  4TQB A;  3U7X A;  2IDR A;  1ZTP A;  3TF2 A;  2IDV A;  1EJH A;  2Q4K A;  5T47 A;  2V8Y A;  5EKV A;  4UEA A;  3AM7 A;  3M93 A;  2W97 A;  2W97 B;  5ABU A;  2GPQ A;  4B6V A;  4B6U A;  2V8W A;  4DT6 A;  5ABV A;  5ABX A;  4TPW A;  4BEA A;  4UE8 A;  4AXG A;  5T46 A;  2JGB A;  4AZA A;  5GW6 A;  1EJ1 A;  5BXV A;  4UE9 A;  1RF8 A;  5ABY A;  3M94 A;  4TQC A;  5EHC A;  2JGC A;  5EIR A;  4UEB A;  1WKW A;  4UED A;  1EJ4 A;  3HXG A;  2WMC A;  4UEC A;  1AP8 A;  4DUM A;  5T48 A; 
#chains in the Genus database with same CATH homology
 1IPB A;  2V8X A;  3HXI A;  5EI3 A;  1IPC A;  1L8B A;  4TQB A;  3U7X A;  2IDR A;  1ZTP A;  3TF2 A;  2IDV A;  1EJH A;  2Q4K A;  5T47 A;  2V8Y A;  5EKV A;  4UEA A;  3AM7 A;  3M93 A;  2W97 A;  2W97 B;  5ABU A;  2GPQ A;  4B6V A;  4B6U A;  2V8W A;  4DT6 A;  5ABV A;  5ABX A;  4TPW A;  4BEA A;  4UE8 A;  4AXG A;  5T46 A;  2JGB A;  4AZA A;  5GW6 A;  1EJ1 A;  5BXV A;  4UE9 A;  1RF8 A;  5ABY A;  3M94 A;  4TQC A;  5EHC A;  2JGC A;  5EIR A;  4UEB A;  1WKW A;  4UED A;  1EJ4 A;  3HXG A;  2WMC A;  4UEC A;  1AP8 A;  4DUM A;  5T48 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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