1EK9A

2.1a x-ray structure of tolc: an integral outer membrane protein and efflux pump component from escherichia coli
Total Genus 160
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
160
sequence length
428
structure length
428
Chain Sequence
ENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDANGINSNATSASLQLTQSIFDMSKWRALTLQEKAAGIQDVTYQTDQQTLILNTATAYFNVLNAIDVLSYTQAQKEAIYRQLDQTTQRFNVGLVAITDVQNARAQYDTVLANELTARNNLDNAVEQLRQITGNYYPELAALNVENFKTDKPQPVNALLKEAEKRNLSLLQARLSQDLAREQIRQAQDGHLPTLDLTASTGISDTSYSGSKTRGAAGTQYDDSNMGQNKVGLSFSLPIYQGGMVNSQVKQAQYNFVGASEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIVDVLDATTTLYNAKQELANARYNYLINQLNIKSALGTLNEQDLLALNNALSKPVSTNPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export.
pubmed doi rcsb
molecule tags Membrane protein
source organism Escherichia coli
molecule keywords OUTER MEMBRANE PROTEIN TOLC
total genus 160
structure length 428
sequence length 428
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2000-03-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02321 OEP Outer membrane efflux protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1600.10 Mainly Alpha Up-down Bundle Outer membrane efflux proteins (OEP) Outer membrane efflux proteins (OEP) 1ek9A00
1EK9A 2WMZA 4K7RA 4MT4A 4MT0A 5AZSA 1WP1A 1TQQA 3PIKA 1YC9A 5BUNA 5IUYA 4Y1KA 2XMNA 5AZOA 5AZPA 4K7KA 4K34A 3D5KA 2VDDA 2VDEA
chains in the Genus database with same CATH superfamily
1EK9A 2WMZA 4K7RA 4MT4A 4MT0A 5AZSA 1WP1A 1TQQA 3PIKA 1YC9A 5BUNA 5IUYA 4Y1KA 2XMNA 5AZOA 5AZPA 4K7KA 4K34A 3D5KA 2VDDA 2VDEA
chains in the Genus database with same CATH topology
1EK9A 2WMZA 4K7RA 4MT4A 4MT0A 5AZSA 1WP1A 1TQQA 3PIKA 1YC9A 5BUNA 5IUYA 4Y1KA 2XMNA 5AZOA 5AZPA 4K7KA 4K34A 3D5KA 2VDDA 2VDEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EK9 A;  2WMZ A;  4K7R A;  4MT4 A;  4MT0 A;  5AZS A;  1WP1 A;  1TQQ A;  3PIK A;  1YC9 A;  5BUN A;  5IUY A;  4Y1K A;  2XMN A;  5AZO A;  5AZP A;  4K7K A;  4K34 A;  3D5K A;  2VDD A;  2VDE A; 
#chains in the Genus database with same CATH topology
 1EK9 A;  2WMZ A;  4K7R A;  4MT4 A;  4MT0 A;  5AZS A;  1WP1 A;  1TQQ A;  3PIK A;  1YC9 A;  5BUN A;  5IUY A;  4Y1K A;  2XMN A;  5AZO A;  5AZP A;  4K7K A;  4K34 A;  3D5K A;  2VDD A;  2VDE A; 
#chains in the Genus database with same CATH homology
 1EK9 A;  2WMZ A;  4K7R A;  4MT4 A;  4MT0 A;  5AZS A;  1WP1 A;  1TQQ A;  3PIK A;  1YC9 A;  5BUN A;  5IUY A;  4Y1K A;  2XMN A;  5AZO A;  5AZP A;  4K7K A;  4K34 A;  3D5K A;  2VDD A;  2VDE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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