1EOOA

Ecorv bound to cognate dna
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
244
structure length
244
Chain Sequence
SLRSDLINALYDENQKYDVCGIISAEGKIYPLGSDTKVLSTIFELFSRPIINKIAEKHGYIVEEPKQQNHYPDFTLYKPSEPNKKIAIDIKTTYTNKENEKIKFTLGGYTSFIRNNTKNIVYPFDQYIAHWIIGYVYTRVATRKSSLKTYNINELNEIPKPYKGVKVFLQDKWVIAGDLAGSGNTTNIGSIHAHYKDFVEGKGIFDSEDEFLDYWRNYERTSQLRNDKYNNISEYRNWIYRGRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/dna
source organism Escherichia coli
publication title Crystallographic snapshots along a protein-induced DNA-bending pathway.
pubmed doi rcsb
molecule keywords DNA (5'-D(*GP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*C)-3')
total genus 78
structure length 244
sequence length 244
chains with identical sequence B
ec nomenclature ec 3.1.21.4: Type II site-specific deoxyribonuclease.
pdb deposition date 2000-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09233 Endonuc-EcoRV Restriction endonuclease EcoRV
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.600.10 Alpha Beta 3-Layer(aba) Sandwich ECO RV Endonuclease; Chain A DNA mismatch repair MutH/Restriction endonuclease, type II 1eooA00
3E42A 1AZ4A 1IAWA 1RVBA 1RVAA 3EBCA 2GIGA 1AZ0A 1SX8A 1TW8A 2RVEA 2GIEA 1XHUA 1BSUA 4PXGA 1XHVA 1B94A 1KC6A 3E45A 2GE5A 2AUDA 1STXA 5HLKA 1EONA 1RV5A 1TX3A 4RVEA 5F8AA 1EOOA 1SUZA 1AZOA 2REUA 1B96A 3E40A 1BSSA 2GIIA 1B95A 3E3YA 1BGBA 1RVCA 1EV7A 2AOQA 1EO3A 3E43A 2GIHA 1RVEA 1AZ3A 2B0DA 2B0EA 3E44A 1SX5A 2AZOA 3E41A 1EOPA 1B97A 1BUAA 2AORA 1EO4A 2GIJA
chains in the Genus database with same CATH superfamily
3E42A 1AZ4A 1IAWA 1RVBA 1RVAA 3EBCA 2GIGA 1AZ0A 1SX8A 1TW8A 2RVEA 2GIEA 1XHUA 1BSUA 4PXGA 1XHVA 1B94A 1KC6A 3E45A 2GE5A 2AUDA 1STXA 5HLKA 1EONA 1RV5A 1TX3A 2F03A 4RVEA 5F8AA 1EOOA 1SUZA 1AZOA 2REUA 2EZVA 1B96A 3NDHA 3E40A 1BSSA 2GIIA 1DMUA 1B95A 3E3YA 1BGBA 1RVCA 1EV7A 2AOQA 1EO3A 3E43A 2GIHA 1RVEA 1AZ3A 2B0DA 2B0EA 3E44A 1SX5A 2AZOA 3E41A 1EOPA 1B97A 1BUAA 2AORA 1EO4A 2GIJA
chains in the Genus database with same CATH topology
3E42A 1AZ4A 1IAWA 1RVBA 1RVAA 3EBCA 2GIGA 1AZ0A 1SX8A 1TW8A 2RVEA 2GIEA 1XHUA 1BSUA 4PXGA 1XHVA 1B94A 1KC6A 3E45A 2GE5A 2AUDA 1STXA 5HLKA 1EONA 1RV5A 1TX3A 4RVEA 5F8AA 1EOOA 1SUZA 1AZOA 2REUA 1B96A 3E40A 1BSSA 2GIIA 1B95A 3E3YA 1BGBA 1RVCA 1EV7A 2AOQA 1EO3A 3E43A 2GIHA 1RVEA 1AZ3A 2B0DA 2B0EA 3E44A 1SX5A 2AZOA 3E41A 1EOPA 1B97A 1BUAA 2AORA 1EO4A 2GIJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3E42 A;  1AZ4 A;  1IAW A;  1RVB A;  1RVA A;  3EBC A;  2GIG A;  1AZ0 A;  1SX8 A;  1TW8 A;  2RVE A;  2GIE A;  1XHU A;  1BSU A;  4PXG A;  1XHV A;  1B94 A;  1KC6 A;  3E45 A;  2GE5 A;  2AUD A;  1STX A;  5HLK A;  1EON A;  1RV5 A;  1TX3 A;  4RVE A;  5F8A A;  1EOO A;  1SUZ A;  1AZO A;  2REU A;  1B96 A;  3E40 A;  1BSS A;  2GII A;  1B95 A;  3E3Y A;  1BGB A;  1RVC A;  1EV7 A;  2AOQ A;  1EO3 A;  3E43 A;  2GIH A;  1RVE A;  1AZ3 A;  2B0D A;  2B0E A;  3E44 A;  1SX5 A;  2AZO A;  3E41 A;  1EOP A;  1B97 A;  1BUA A;  2AOR A;  1EO4 A;  2GIJ A; 
#chains in the Genus database with same CATH topology
 3E42 A;  1AZ4 A;  1IAW A;  1RVB A;  1RVA A;  3EBC A;  2GIG A;  1AZ0 A;  1SX8 A;  1TW8 A;  2RVE A;  2GIE A;  1XHU A;  1BSU A;  4PXG A;  1XHV A;  1B94 A;  1KC6 A;  3E45 A;  2GE5 A;  2AUD A;  1STX A;  5HLK A;  1EON A;  1RV5 A;  1TX3 A;  2F03 A;  4RVE A;  5F8A A;  1EOO A;  1SUZ A;  1AZO A;  2REU A;  2EZV A;  1B96 A;  3NDH A;  3E40 A;  1BSS A;  2GII A;  1DMU A;  1B95 A;  3E3Y A;  1BGB A;  1RVC A;  1EV7 A;  2AOQ A;  1EO3 A;  3E43 A;  2GIH A;  1RVE A;  1AZ3 A;  2B0D A;  2B0E A;  3E44 A;  1SX5 A;  2AZO A;  3E41 A;  1EOP A;  1B97 A;  1BUA A;  2AOR A;  1EO4 A;  2GIJ A; 
#chains in the Genus database with same CATH homology
 3E42 A;  1AZ4 A;  1IAW A;  1RVB A;  1RVA A;  3EBC A;  2GIG A;  1AZ0 A;  1SX8 A;  1TW8 A;  2RVE A;  2GIE A;  1XHU A;  1BSU A;  4PXG A;  1XHV A;  1B94 A;  1KC6 A;  3E45 A;  2GE5 A;  2AUD A;  1STX A;  5HLK A;  1EON A;  1RV5 A;  1TX3 A;  4RVE A;  5F8A A;  1EOO A;  1SUZ A;  1AZO A;  2REU A;  1B96 A;  3E40 A;  1BSS A;  2GII A;  1B95 A;  3E3Y A;  1BGB A;  1RVC A;  1EV7 A;  2AOQ A;  1EO3 A;  3E43 A;  2GIH A;  1RVE A;  1AZ3 A;  2B0D A;  2B0E A;  3E44 A;  1SX5 A;  2AZO A;  3E41 A;  1EOP A;  1B97 A;  1BUA A;  2AOR A;  1EO4 A;  2GIJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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