1EOOA

Ecorv bound to cognate dna
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
244
structure length
244
Chain Sequence
SLRSDLINALYDENQKYDVCGIISAEGKIYPLGSDTKVLSTIFELFSRPIINKIAEKHGYIVEEPKQQNHYPDFTLYKPSEPNKKIAIDIKTTYTNKENEKIKFTLGGYTSFIRNNTKNIVYPFDQYIAHWIIGYVYTRVATRKSSLKTYNINELNEIPKPYKGVKVFLQDKWVIAGDLAGSGNTTNIGSIHAHYKDFVEGKGIFDSEDEFLDYWRNYERTSQLRNDKYNNISEYRNWIYRGRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic snapshots along a protein-induced DNA-bending pathway.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Escherichia coli
molecule keywords DNA (5'-D(*GP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*C)-3')
total genus 78
structure length 244
sequence length 244
chains with identical sequence B
ec nomenclature ec 3.1.21.4: Type II site-specific deoxyribonuclease.
pdb deposition date 2000-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09233 Endonuc-EcoRV Restriction endonuclease EcoRV
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.600.10 Alpha Beta 3-Layer(aba) Sandwich ECO RV Endonuclease; Chain A DNA mismatch repair MutH/Restriction endonuclease, type II 1eooA00
1XHVA 1B94A 3E42A 1XHUA 1KC6A 2B0EA 1BSUA 3E45A 2AZOA 3E44A 4PXGA 2B0DA 4RVEA 5F8AA 2REUA 1SX5A 2GIEA 1BUAA 1EO3A 1AZ0A 2GIIA 3E43A 1BGBA 3E40A 1RVBA 1EV7A 1EONA 1EOPA 1RV5A 3E3YA 1EO4A 1B97A 2GIGA 1B96A 1RVEA 1RVAA 1BSSA 3EBCA 2AUDA 1RVCA 5HLKA 1STXA 1AZOA 3E41A 2AORA 2RVEA 2GE5A 1TW8A 1B95A 1AZ4A 2GIHA 1SUZA 1TX3A 2AOQA 1IAWA 2GIJA 1SX8A 1EOOA 1AZ3A
chains in the Genus database with same CATH superfamily
1XHVA 1B94A 3E42A 1XHUA 1KC6A 2B0EA 1BSUA 3E45A 2EZVA 2AZOA 3E44A 4PXGA 2B0DA 4RVEA 5F8AA 2REUA 1SX5A 2GIEA 1BUAA 1EO3A 1AZ0A 2GIIA 3E43A 1BGBA 3E40A 1RVBA 1EV7A 1DMUA 1EONA 1EOPA 1RV5A 3E3YA 1EO4A 1B97A 2GIGA 1B96A 1RVEA 1RVAA 1BSSA 3EBCA 2AUDA 3NDHA 1RVCA 5HLKA 1STXA 1AZOA 2F03A 3E41A 2AORA 2RVEA 2GE5A 1TW8A 1B95A 1AZ4A 2GIHA 1SUZA 1TX3A 2AOQA 1IAWA 2GIJA 1SX8A 1EOOA 1AZ3A
chains in the Genus database with same CATH topology
1XHVA 1B94A 3E42A 1XHUA 1KC6A 2B0EA 1BSUA 3E45A 2AZOA 3E44A 4PXGA 2B0DA 4RVEA 5F8AA 2REUA 1SX5A 2GIEA 1BUAA 1EO3A 1AZ0A 2GIIA 3E43A 1BGBA 3E40A 1RVBA 1EV7A 1EONA 1EOPA 1RV5A 3E3YA 1EO4A 1B97A 2GIGA 1B96A 1RVEA 1RVAA 1BSSA 3EBCA 2AUDA 1RVCA 5HLKA 1STXA 1AZOA 3E41A 2AORA 2RVEA 2GE5A 1TW8A 1B95A 1AZ4A 2GIHA 1SUZA 1TX3A 2AOQA 1IAWA 2GIJA 1SX8A 1EOOA 1AZ3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XHV A;  1B94 A;  3E42 A;  1XHU A;  1KC6 A;  2B0E A;  1BSU A;  3E45 A;  2AZO A;  3E44 A;  4PXG A;  2B0D A;  4RVE A;  5F8A A;  2REU A;  1SX5 A;  2GIE A;  1BUA A;  1EO3 A;  1AZ0 A;  2GII A;  3E43 A;  1BGB A;  3E40 A;  1RVB A;  1EV7 A;  1EON A;  1EOP A;  1RV5 A;  3E3Y A;  1EO4 A;  1B97 A;  2GIG A;  1B96 A;  1RVE A;  1RVA A;  1BSS A;  3EBC A;  2AUD A;  1RVC A;  5HLK A;  1STX A;  1AZO A;  3E41 A;  2AOR A;  2RVE A;  2GE5 A;  1TW8 A;  1B95 A;  1AZ4 A;  2GIH A;  1SUZ A;  1TX3 A;  2AOQ A;  1IAW A;  2GIJ A;  1SX8 A;  1EOO A;  1AZ3 A; 
#chains in the Genus database with same CATH topology
 1XHV A;  1B94 A;  3E42 A;  1XHU A;  1KC6 A;  2B0E A;  1BSU A;  3E45 A;  2EZV A;  2AZO A;  3E44 A;  4PXG A;  2B0D A;  4RVE A;  5F8A A;  2REU A;  1SX5 A;  2GIE A;  1BUA A;  1EO3 A;  1AZ0 A;  2GII A;  3E43 A;  1BGB A;  3E40 A;  1RVB A;  1EV7 A;  1DMU A;  1EON A;  1EOP A;  1RV5 A;  3E3Y A;  1EO4 A;  1B97 A;  2GIG A;  1B96 A;  1RVE A;  1RVA A;  1BSS A;  3EBC A;  2AUD A;  3NDH A;  1RVC A;  5HLK A;  1STX A;  1AZO A;  2F03 A;  3E41 A;  2AOR A;  2RVE A;  2GE5 A;  1TW8 A;  1B95 A;  1AZ4 A;  2GIH A;  1SUZ A;  1TX3 A;  2AOQ A;  1IAW A;  2GIJ A;  1SX8 A;  1EOO A;  1AZ3 A; 
#chains in the Genus database with same CATH homology
 1XHV A;  1B94 A;  3E42 A;  1XHU A;  1KC6 A;  2B0E A;  1BSU A;  3E45 A;  2AZO A;  3E44 A;  4PXG A;  2B0D A;  4RVE A;  5F8A A;  2REU A;  1SX5 A;  2GIE A;  1BUA A;  1EO3 A;  1AZ0 A;  2GII A;  3E43 A;  1BGB A;  3E40 A;  1RVB A;  1EV7 A;  1EON A;  1EOP A;  1RV5 A;  3E3Y A;  1EO4 A;  1B97 A;  2GIG A;  1B96 A;  1RVE A;  1RVA A;  1BSS A;  3EBC A;  2AUD A;  1RVC A;  5HLK A;  1STX A;  1AZO A;  3E41 A;  2AOR A;  2RVE A;  2GE5 A;  1TW8 A;  1B95 A;  1AZ4 A;  2GIH A;  1SUZ A;  1TX3 A;  2AOQ A;  1IAW A;  2GIJ A;  1SX8 A;  1EOO A;  1AZ3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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