1EOOA

Ecorv bound to cognate dna
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
244
structure length
244
Chain Sequence
SLRSDLINALYDENQKYDVCGIISAEGKIYPLGSDTKVLSTIFELFSRPIINKIAEKHGYIVEEPKQQNHYPDFTLYKPSEPNKKIAIDIKTTYTNKENEKIKFTLGGYTSFIRNNTKNIVYPFDQYIAHWIIGYVYTRVATRKSSLKTYNINELNEIPKPYKGVKVFLQDKWVIAGDLAGSGNTTNIGSIHAHYKDFVEGKGIFDSEDEFLDYWRNYERTSQLRNDKYNNISEYRNWIYRGRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic snapshots along a protein-induced DNA-bending pathway.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Escherichia coli
molecule keywords DNA (5'-D(*GP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*C)-3')
total genus 78
structure length 244
sequence length 244
chains with identical sequence B
ec nomenclature ec 3.1.21.4: Type II site-specific deoxyribonuclease.
pdb deposition date 2000-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09233 Endonuc-EcoRV Restriction endonuclease EcoRV
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.600.10 Alpha Beta 3-Layer(aba) Sandwich ECO RV Endonuclease; Chain A DNA mismatch repair MutH/Restriction endonuclease, type II 1eooA00
1EV7A 1RV5A 2REUA 1B94A 2GE5A 2GIHA 2AORA 1EONA 2GIIA 3E41A 1AZ3A 3E40A 1RVAA 1AZOA 1TW8A 2GIEA 5F8AA 1EOPA 2B0DA 2B0EA 4PXGA 2AOQA 3E43A 1RVCA 1SX8A 1BSSA 1RVEA 1KC6A 1RVBA 1EO3A 1SUZA 2AZOA 1EOOA 1BSUA 4RVEA 1IAWA 1AZ4A 1XHVA 1B96A 3EBCA 1B97A 1EO4A 2GIGA 5HLKA 1TX3A 1SX5A 1BUAA 1BGBA 2RVEA 1AZ0A 3E3YA 3E45A 3E42A 1B95A 1XHUA 3E44A 2GIJA 1STXA 2AUDA
chains in the Genus database with same CATH superfamily
1EV7A 1RV5A 2REUA 1B94A 2GE5A 2GIHA 2AORA 1EONA 2GIIA 3E41A 1AZ3A 3E40A 3NDHA 1RVAA 1AZOA 2F03A 1TW8A 2GIEA 5F8AA 1EOPA 2B0DA 2B0EA 4PXGA 2AOQA 3E43A 1RVCA 1SX8A 1BSSA 1RVEA 1KC6A 1RVBA 1EO3A 1SUZA 2AZOA 1EOOA 1BSUA 1DMUA 4RVEA 1IAWA 1AZ4A 1XHVA 1B96A 3EBCA 1B97A 1EO4A 2GIGA 5HLKA 1TX3A 1SX5A 1BUAA 1BGBA 2RVEA 2EZVA 1AZ0A 3E3YA 3E45A 3E42A 1B95A 1XHUA 3E44A 2GIJA 1STXA 2AUDA
chains in the Genus database with same CATH topology
1EV7A 1RV5A 2REUA 1B94A 2GE5A 2GIHA 2AORA 1EONA 2GIIA 3E41A 1AZ3A 3E40A 1RVAA 1AZOA 1TW8A 2GIEA 5F8AA 1EOPA 2B0DA 2B0EA 4PXGA 2AOQA 3E43A 1RVCA 1SX8A 1BSSA 1RVEA 1KC6A 1RVBA 1EO3A 1SUZA 2AZOA 1EOOA 1BSUA 4RVEA 1IAWA 1AZ4A 1XHVA 1B96A 3EBCA 1B97A 1EO4A 2GIGA 5HLKA 1TX3A 1SX5A 1BUAA 1BGBA 2RVEA 1AZ0A 3E3YA 3E45A 3E42A 1B95A 1XHUA 3E44A 2GIJA 1STXA 2AUDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EV7 A;  1RV5 A;  2REU A;  1B94 A;  2GE5 A;  2GIH A;  2AOR A;  1EON A;  2GII A;  3E41 A;  1AZ3 A;  3E40 A;  1RVA A;  1AZO A;  1TW8 A;  2GIE A;  5F8A A;  1EOP A;  2B0D A;  2B0E A;  4PXG A;  2AOQ A;  3E43 A;  1RVC A;  1SX8 A;  1BSS A;  1RVE A;  1KC6 A;  1RVB A;  1EO3 A;  1SUZ A;  2AZO A;  1EOO A;  1BSU A;  4RVE A;  1IAW A;  1AZ4 A;  1XHV A;  1B96 A;  3EBC A;  1B97 A;  1EO4 A;  2GIG A;  5HLK A;  1TX3 A;  1SX5 A;  1BUA A;  1BGB A;  2RVE A;  1AZ0 A;  3E3Y A;  3E45 A;  3E42 A;  1B95 A;  1XHU A;  3E44 A;  2GIJ A;  1STX A;  2AUD A; 
#chains in the Genus database with same CATH topology
 1EV7 A;  1RV5 A;  2REU A;  1B94 A;  2GE5 A;  2GIH A;  2AOR A;  1EON A;  2GII A;  3E41 A;  1AZ3 A;  3E40 A;  3NDH A;  1RVA A;  1AZO A;  2F03 A;  1TW8 A;  2GIE A;  5F8A A;  1EOP A;  2B0D A;  2B0E A;  4PXG A;  2AOQ A;  3E43 A;  1RVC A;  1SX8 A;  1BSS A;  1RVE A;  1KC6 A;  1RVB A;  1EO3 A;  1SUZ A;  2AZO A;  1EOO A;  1BSU A;  1DMU A;  4RVE A;  1IAW A;  1AZ4 A;  1XHV A;  1B96 A;  3EBC A;  1B97 A;  1EO4 A;  2GIG A;  5HLK A;  1TX3 A;  1SX5 A;  1BUA A;  1BGB A;  2RVE A;  2EZV A;  1AZ0 A;  3E3Y A;  3E45 A;  3E42 A;  1B95 A;  1XHU A;  3E44 A;  2GIJ A;  1STX A;  2AUD A; 
#chains in the Genus database with same CATH homology
 1EV7 A;  1RV5 A;  2REU A;  1B94 A;  2GE5 A;  2GIH A;  2AOR A;  1EON A;  2GII A;  3E41 A;  1AZ3 A;  3E40 A;  1RVA A;  1AZO A;  1TW8 A;  2GIE A;  5F8A A;  1EOP A;  2B0D A;  2B0E A;  4PXG A;  2AOQ A;  3E43 A;  1RVC A;  1SX8 A;  1BSS A;  1RVE A;  1KC6 A;  1RVB A;  1EO3 A;  1SUZ A;  2AZO A;  1EOO A;  1BSU A;  4RVE A;  1IAW A;  1AZ4 A;  1XHV A;  1B96 A;  3EBC A;  1B97 A;  1EO4 A;  2GIG A;  5HLK A;  1TX3 A;  1SX5 A;  1BUA A;  1BGB A;  2RVE A;  1AZ0 A;  3E3Y A;  3E45 A;  3E42 A;  1B95 A;  1XHU A;  3E44 A;  2GIJ A;  1STX A;  2AUD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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