1HRTI

The structure of a complex of bovine alpha-thrombin and recombinant hirudin at 2.8 angstroms resolution
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
65
structure length
65
Chain Sequence
VVYTDCTESGQNLCLCEGSNVCGQGNKCILGSDGEKNQCVTGEGTPKPQSHNDGDFEEIPEEYLQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of a complex of bovine alpha-thrombin and recombinant hirudin at 2.8-A resolution.
pubmed rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Bos taurus
molecule keywords THROMBIN (SMALL SUBUNIT)
total genus 6
structure length 65
sequence length 65
ec nomenclature
pdb deposition date 1993-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00713 Hirudin Hirudin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.10.10 Mainly Beta Distorted Sandwich Thrombin Inhibitor (Hirudin); Chain I Thrombin Inhibitor (Hirudin), subunit I 1hrtI00
1E0FI 6HIRA 2HIRA 1HICA 4MLFD 2JOOA 5HIRA 4HTCI 1HRTI 2PW8I 4HIRA
chains in the Genus database with same CATH superfamily
1E0FI 6HIRA 2HIRA 1HICA 4MLFD 2JOOA 5HIRA 4HTCI 1HRTI 2PW8I 4HIRA
chains in the Genus database with same CATH topology
1E0FI 6HIRA 2HIRA 1HICA 4MLFD 2JOOA 5HIRA 4HTCI 1HRTI 2PW8I 4HIRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E0F I;  6HIR A;  2HIR A;  1HIC A;  4MLF D;  2JOO A;  5HIR A;  4HTC I;  1HRT I;  2PW8 I;  4HIR A; 
#chains in the Genus database with same CATH topology
 1E0F I;  6HIR A;  2HIR A;  1HIC A;  4MLF D;  2JOO A;  5HIR A;  4HTC I;  1HRT I;  2PW8 I;  4HIR A; 
#chains in the Genus database with same CATH homology
 1E0F I;  6HIR A;  2HIR A;  1HIC A;  4MLF D;  2JOO A;  5HIR A;  4HTC I;  1HRT I;  2PW8 I;  4HIR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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