1IPBA

Crystal structure of eukaryotic initiation factor 4e complexed with 7-methyl gpppa
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
191
structure length
191
Chain Sequence
EVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of 7-methylguanosine 5'-triphosphate (m(7)GTP)- and P(1)-7-methylguanosine-P(3)-adenosine-5',5'-triphosphate (m(7)GpppA)-bound human full-length eukaryotic initiation factor 4E: biological importance of the C-terminal flexible region
pubmed doi rcsb
molecule tags Rna binding protein
source organism Homo sapiens
molecule keywords EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
total genus 57
structure length 191
sequence length 191
ec nomenclature
pdb deposition date 2001-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01652 IF4E Eukaryotic initiation factor 4E
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.760.10 Alpha Beta 2-Layer Sandwich RNA Cap, Translation Initiation Factor Eif4e RNA Cap, Translation Initiation Factor Eif4e 1ipbA00
3M94A 5EKVA 2GPQA 3M93A 2Q4KA 2V8YA 2JGCA 2WMCA 4TQCA 4UEDA 4UEAA 4B6UA 3TF2A 4TQBA 4AXGA 1AP8A 5ABYA 4UE8A 1ZTPA 1L8BA 1EJ4A 4DT6A 3AM7A 1RF8A 2W97A 1EJ1A 1IPBA 5EHCA 5T47A 2IDRA 5ABUA 3HXGA 5EI3A 4TPWA 4UE9A 5EIRA 2W97B 1WKWA 3HXIA 3U7XA 2V8XA 5GW6A 5T46A 5T48A 4B6VA 5ABVA 5ABXA 4BEAA 2V8WA 4DUMA 1IPCA 4AZAA 5BXVA 4UECA 1EJHA 4UEBA 2JGBA 2IDVA
chains in the Genus database with same CATH superfamily
3M94A 5EKVA 2GPQA 3M93A 2Q4KA 2V8YA 2JGCA 2WMCA 4TQCA 4UEDA 4UEAA 4B6UA 3TF2A 4TQBA 4AXGA 1AP8A 5ABYA 4UE8A 1ZTPA 1L8BA 1EJ4A 4DT6A 3AM7A 1RF8A 2W97A 1EJ1A 1IPBA 5EHCA 5T47A 2IDRA 5ABUA 3HXGA 5EI3A 4TPWA 4UE9A 5EIRA 2W97B 1WKWA 3HXIA 3U7XA 2V8XA 5GW6A 5T46A 5T48A 4B6VA 5ABVA 5ABXA 4BEAA 2V8WA 4DUMA 1IPCA 4AZAA 5BXVA 4UECA 1EJHA 4UEBA 2JGBA 2IDVA
chains in the Genus database with same CATH topology
3M94A 5EKVA 2GPQA 3M93A 2Q4KA 2V8YA 2JGCA 2WMCA 4TQCA 4UEDA 4UEAA 4B6UA 3TF2A 4TQBA 4AXGA 1AP8A 5ABYA 4UE8A 1ZTPA 1L8BA 1EJ4A 4DT6A 3AM7A 1RF8A 2W97A 1EJ1A 1IPBA 5EHCA 5T47A 2IDRA 5ABUA 3HXGA 5EI3A 4TPWA 4UE9A 5EIRA 2W97B 1WKWA 3HXIA 3U7XA 2V8XA 5GW6A 5T46A 5T48A 4B6VA 5ABVA 5ABXA 4BEAA 2V8WA 4DUMA 1IPCA 4AZAA 5BXVA 4UECA 1EJHA 4UEBA 2JGBA 2IDVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M94 A;  5EKV A;  2GPQ A;  3M93 A;  2Q4K A;  2V8Y A;  2JGC A;  2WMC A;  4TQC A;  4UED A;  4UEA A;  4B6U A;  3TF2 A;  4TQB A;  4AXG A;  1AP8 A;  5ABY A;  4UE8 A;  1ZTP A;  1L8B A;  1EJ4 A;  4DT6 A;  3AM7 A;  1RF8 A;  2W97 A;  1EJ1 A;  1IPB A;  5EHC A;  5T47 A;  2IDR A;  5ABU A;  3HXG A;  5EI3 A;  4TPW A;  4UE9 A;  5EIR A;  2W97 B;  1WKW A;  3HXI A;  3U7X A;  2V8X A;  5GW6 A;  5T46 A;  5T48 A;  4B6V A;  5ABV A;  5ABX A;  4BEA A;  2V8W A;  4DUM A;  1IPC A;  4AZA A;  5BXV A;  4UEC A;  1EJH A;  4UEB A;  2JGB A;  2IDV A; 
#chains in the Genus database with same CATH topology
 3M94 A;  5EKV A;  2GPQ A;  3M93 A;  2Q4K A;  2V8Y A;  2JGC A;  2WMC A;  4TQC A;  4UED A;  4UEA A;  4B6U A;  3TF2 A;  4TQB A;  4AXG A;  1AP8 A;  5ABY A;  4UE8 A;  1ZTP A;  1L8B A;  1EJ4 A;  4DT6 A;  3AM7 A;  1RF8 A;  2W97 A;  1EJ1 A;  1IPB A;  5EHC A;  5T47 A;  2IDR A;  5ABU A;  3HXG A;  5EI3 A;  4TPW A;  4UE9 A;  5EIR A;  2W97 B;  1WKW A;  3HXI A;  3U7X A;  2V8X A;  5GW6 A;  5T46 A;  5T48 A;  4B6V A;  5ABV A;  5ABX A;  4BEA A;  2V8W A;  4DUM A;  1IPC A;  4AZA A;  5BXV A;  4UEC A;  1EJH A;  4UEB A;  2JGB A;  2IDV A; 
#chains in the Genus database with same CATH homology
 3M94 A;  5EKV A;  2GPQ A;  3M93 A;  2Q4K A;  2V8Y A;  2JGC A;  2WMC A;  4TQC A;  4UED A;  4UEA A;  4B6U A;  3TF2 A;  4TQB A;  4AXG A;  1AP8 A;  5ABY A;  4UE8 A;  1ZTP A;  1L8B A;  1EJ4 A;  4DT6 A;  3AM7 A;  1RF8 A;  2W97 A;  1EJ1 A;  1IPB A;  5EHC A;  5T47 A;  2IDR A;  5ABU A;  3HXG A;  5EI3 A;  4TPW A;  4UE9 A;  5EIR A;  2W97 B;  1WKW A;  3HXI A;  3U7X A;  2V8X A;  5GW6 A;  5T46 A;  5T48 A;  4B6V A;  5ABV A;  5ABX A;  4BEA A;  2V8W A;  4DUM A;  1IPC A;  4AZA A;  5BXV A;  4UEC A;  1EJH A;  4UEB A;  2JGB A;  2IDV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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