1KP8A

Structural basis for groel-assisted protein folding from the crystal structure of (groel-kmgatp)14 at 2.0 a resolution
Total Genus 167
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
167
sequence length
525
structure length
525
Chain Sequence
AAKDVKFGNDAGVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTVAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNADQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for GroEL-assisted Protein Folding from the Crystal Structure of (GroEL-KMgATP)14 at 2.0 A Resolution
pubmed doi rcsb
molecule tags Chaperone
source organism Escherichia coli
molecule keywords groEL protein
total genus 167
structure length 525
sequence length 525
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L, M, N
ec nomenclature
pdb deposition date 2001-12-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00118 Cpn60_TCP1 TCP-1/cpn60 chaperonin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.560.10 Mainly Alpha Orthogonal Bundle GROEL; domain 1 GroEL-like equatorial domain 1kp8A01
3.30.260.10 Alpha Beta 2-Layer Sandwich GROEL; domain 2 TCP-1-like chaperonin intermediate domain 1kp8A02
3.50.7.10 Alpha Beta 3-Layer(bba) Sandwich GroEL GroEL 1kp8A03
2EU1A 5CDJA 1OELA 3M6CA 1Q3RA 3KFEA 3WVLA 1SS8A 4KI8A 3RUQA 3OSXA 3KTTB 4PJ1A 2NWCA 1FYAA 1DK7A 4XCDA 5CDKA 1MNFA 3RUSA 1PF9A 3VZ8A 3AQ1B 1ASXA 4XCIB 5CDIA 1Q3QA 3E76A 3RTKA 1SX3A 4PKNA 1A6EB 1FY9A 1A6EA 4WSCA 1GMLA 4PKOA 1GRLA 1SRVA 1Q3SA 1A6DB 1A6DA 1PCQA 1Q2VA 3VZ6A 3VZ7A 1AONA 4WGLA 1E0RB 1KP8A 1SVTA 4XCGB 1KIDA 1JONA 1IOKA 4XCGA 4HELA 3RUVA 3KFBA 1ASSA 1LA1A 1XCKA 3RUWA 1DKDA 3KO1A 1SX4A 1SJPA 1GN1A
chains in the Genus database with same CATH superfamily
2EU1A 5CDJA 1OELA 3M6CA 1Q3RA 3KFEA 3WVLA 1SS8A 4KI8A 3RUQA 3OSXA 3KTTB 4PJ1A 2NWCA 1FYAA 1DK7A 4XCDA 5CDKA 1MNFA 3RUSA 1PF9A 3VZ8A 3AQ1B 1ASXA 4XCIB 5CDIA 1Q3QA 3E76A 3RTKA 1SX3A 4PKNA 1A6EB 1FY9A 1A6EA 4WSCA 1GMLA 4PKOA 1GRLA 1SRVA 1Q3SA 1A6DB 1A6DA 1PCQA 1Q2VA 3VZ6A 3VZ7A 4MO1A 1AONA 4WGLA 1E0RB 1KP8A 1SVTA 4XCGB 1KIDA 1JONA 1IOKA 4XCGA 4HELA 3RUVA 3KFBA 1ASSA 1LA1A 1XCKA 3RUWA 1DKDA 3KO1A 1SX4A 1SJPA 1GN1A
chains in the Genus database with same CATH topology
2EU1A 5CDJA 1OELA 3M6CA 1Q3RA 3KFEA 3WVLA 1SS8A 4KI8A 3RUQA 3OSXA 3KTTB 4PJ1A 2NWCA 1FYAA 1DK7A 4XCDA 5CDKA 1MNFA 3RUSA 1PF9A 3VZ8A 3AQ1B 1ASXA 4XCIB 5CDIA 1Q3QA 3E76A 3RTKA 1SX3A 4PKNA 1A6EB 1FY9A 1A6EA 4WSCA 1GMLA 4PKOA 1GRLA 1SRVA 1Q3SA 1A6DB 1A6DA 1PCQA 1Q2VA 3VZ6A 3VZ7A 1AONA 4WGLA 1E0RB 1KP8A 1SVTA 4XCGB 1KIDA 1JONA 1IOKA 4XCGA 4HELA 3RUVA 3KFBA 1ASSA 1LA1A 1XCKA 3RUWA 1DKDA 3KO1A 1SX4A 1SJPA 1GN1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EU1 A;  5CDJ A;  1OEL A;  3M6C A;  1Q3R A;  3KFE A;  3WVL A;  1SS8 A;  4KI8 A;  3RUQ A;  3OSX A;  3KTT B;  4PJ1 A;  2NWC A;  1FYA A;  1DK7 A;  4XCD A;  5CDK A;  1MNF A;  3RUS A;  1PF9 A;  3VZ8 A;  3AQ1 B;  1ASX A;  4XCI B;  5CDI A;  1Q3Q A;  3E76 A;  3RTK A;  1SX3 A;  4PKN A;  1A6E B;  1FY9 A;  1A6E A;  4WSC A;  1GML A;  4PKO A;  1GRL A;  1SRV A;  1Q3S A;  1A6D B;  1A6D A;  1PCQ A;  1Q2V A;  3VZ6 A;  3VZ7 A;  1AON A;  4WGL A;  1E0R B;  1KP8 A;  1SVT A;  4XCG B;  1KID A;  1JON A;  1IOK A;  4XCG A;  4HEL A;  3RUV A;  3KFB A;  1ASS A;  1LA1 A;  1XCK A;  3RUW A;  1DKD A;  3KO1 A;  1SX4 A;  1SJP A;  1GN1 A; 
#chains in the Genus database with same CATH topology
 2EU1 A;  5CDJ A;  1OEL A;  3M6C A;  1Q3R A;  3KFE A;  3WVL A;  1SS8 A;  4KI8 A;  3RUQ A;  3OSX A;  3KTT B;  4PJ1 A;  2NWC A;  1FYA A;  1DK7 A;  4XCD A;  5CDK A;  1MNF A;  3RUS A;  1PF9 A;  3VZ8 A;  3AQ1 B;  1ASX A;  4XCI B;  5CDI A;  1Q3Q A;  3E76 A;  3RTK A;  1SX3 A;  4PKN A;  1A6E B;  1FY9 A;  1A6E A;  4WSC A;  1GML A;  4PKO A;  1GRL A;  1SRV A;  1Q3S A;  1A6D B;  1A6D A;  1PCQ A;  1Q2V A;  3VZ6 A;  3VZ7 A;  4MO1 A;  1AON A;  4WGL A;  1E0R B;  1KP8 A;  1SVT A;  4XCG B;  1KID A;  1JON A;  1IOK A;  4XCG A;  4HEL A;  3RUV A;  3KFB A;  1ASS A;  1LA1 A;  1XCK A;  3RUW A;  1DKD A;  3KO1 A;  1SX4 A;  1SJP A;  1GN1 A; 
#chains in the Genus database with same CATH homology
 2EU1 A;  5CDJ A;  1OEL A;  3M6C A;  1Q3R A;  3KFE A;  3WVL A;  1SS8 A;  4KI8 A;  3RUQ A;  3OSX A;  3KTT B;  4PJ1 A;  2NWC A;  1FYA A;  1DK7 A;  4XCD A;  5CDK A;  1MNF A;  3RUS A;  1PF9 A;  3VZ8 A;  3AQ1 B;  1ASX A;  4XCI B;  5CDI A;  1Q3Q A;  3E76 A;  3RTK A;  1SX3 A;  4PKN A;  1A6E B;  1FY9 A;  1A6E A;  4WSC A;  1GML A;  4PKO A;  1GRL A;  1SRV A;  1Q3S A;  1A6D B;  1A6D A;  1PCQ A;  1Q2V A;  3VZ6 A;  3VZ7 A;  1AON A;  4WGL A;  1E0R B;  1KP8 A;  1SVT A;  4XCG B;  1KID A;  1JON A;  1IOK A;  4XCG A;  4HEL A;  3RUV A;  3KFB A;  1ASS A;  1LA1 A;  1XCK A;  3RUW A;  1DKD A;  3KO1 A;  1SX4 A;  1SJP A;  1GN1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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