1LRUA

Crystal structure of e.coli peptide deformylase complexed with antibiotic actinonin
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
164
structure length
164
Chain Sequence
SVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVEKLDRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structures of four peptide deformylases bound to the antibiotic actinonin reveal two distinct types: a platform for the structure-based design of antibacterial agents.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords PEPTIDE DEFORMYLASE
total genus 47
structure length 164
sequence length 164
chains with identical sequence B, C
ec nomenclature ec 3.5.1.88: Peptide deformylase.
pdb deposition date 2002-05-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01327 Pep_deformylase Polypeptide deformylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.45.10 Alpha Beta Alpha-Beta Complex Peptide Deformylase Peptide deformylase 1lruA00
1G27A 1XEOA 1ICJA 1LQWA 2AIAA 3M6OA 3M6RA 5CVQA 3UWBA 1VEZA 3PN5A 1BS4A 2AIEP 1XEMA 1SV2A 1LRUA 3PN3A 1BS5A 3PN4A 1JYMA 3SVJP 4JE6A 3QU1A 5CVPA 4DR9A 1VEVA 1S17A 5CWYA 1WS1A 2KMNA 3FWXA 3K6LA 3L87A 1ZY1A 5JF4A 5JF5A 5JEYA 1RQCA 3U7KA 1BSKA 1V3YA 3G5KA 4WXKA 5JF3A 3CPMA 5J46A 3G5PA 3G6NA 1DEFA 1LRYA 3U7NA 5KOBA 4EOXP 1SZZA 1ZY0A 1BSZA 2EW5A 5JEXA 3O3JA 2DEFA 2EW7A 3PN6A 1ZXZA 1BS8A 4DR8A 5I2BA 5CWXA 5CP0A 1Y6HA 5JEZA 1BS7A 4AL2A 5JF6A 1LMEA 3E3UA 4JE8A 1Q1YA 1WS0A 3STRP 1IX1A 5CXJA 3M6PA 4AL3A 5JF7A 5JF0A 1RL4A 5E5DA 1LQYA 2EW6A 1XENA 5CY8A 2OS0A 2AI9A 2AI7A 1BSJA 5HGWA 1DFFA 3U7LA 5CVKA 3M6QA 5CX0A 5JF1A 2OS3A 1LM6A 3OCAA 2OS1A 4WXLA 4JE7A 2W3TA 3U7MA 3SW8P 3UWAA 1N5NA 1G2AA 3CMDA 1LM4A 1BS6A 4E9BA 3U04A 5T8ZA 5JF2A 2AI8A 2W3UA 5CPDA 4E9AA 3PN2A 2OKLA 4NT8A 5JF8A 1LMHA 1VEYA 4AZ4A 5CY7A
chains in the Genus database with same CATH superfamily
1G27A 1XEOA 1ICJA 1LQWA 2AIAA 3M6OA 3M6RA 5CVQA 3UWBA 1VEZA 3PN5A 1BS4A 2AIEP 1XEMA 1SV2A 1LRUA 3PN3A 1BS5A 3PN4A 1JYMA 3SVJP 4JE6A 3QU1A 5CVPA 4DR9A 1VEVA 1S17A 5CWYA 1WS1A 2KMNA 3FWXA 3K6LA 3L87A 1ZY1A 5JF4A 5JF5A 5JEYA 1RQCA 3U7KA 1BSKA 1V3YA 3G5KA 4WXKA 5JF3A 3CPMA 5J46A 3G5PA 3G6NA 1DEFA 1LRYA 3U7NA 5KOBA 4EOXP 1SZZA 1ZY0A 1BSZA 2EW5A 5JEXA 3O3JA 2DEFA 2EW7A 3PN6A 1ZXZA 1BS8A 4DR8A 5I2BA 5CWXA 5CP0A 1Y6HA 5JEZA 1BS7A 4AL2A 5JF6A 1LMEA 3E3UA 4JE8A 1Q1YA 1WS0A 3STRP 1IX1A 5CXJA 3M6PA 4AL3A 5JF7A 5JF0A 1RL4A 5E5DA 1LQYA 2EW6A 1XENA 5CY8A 2OS0A 2AI9A 2AI7A 1BSJA 5HGWA 1DFFA 3U7LA 5CVKA 3M6QA 5CX0A 5JF1A 2OS3A 1LM6A 3OCAA 2OS1A 4WXLA 4JE7A 2W3TA 3U7MA 3SW8P 3UWAA 1N5NA 1G2AA 3CMDA 1LM4A 1BS6A 4E9BA 3U04A 5T8ZA 5JF2A 2AI8A 2W3UA 5CPDA 4E9AA 3PN2A 2OKLA 4NT8A 5JF8A 1LMHA 1VEYA 4AZ4A 5CY7A
chains in the Genus database with same CATH topology
1G27A 1XEOA 1ICJA 1LQWA 2AIAA 3M6OA 3M6RA 5CVQA 3UWBA 1VEZA 3PN5A 1BS4A 2AIEP 1XEMA 1SV2A 1LRUA 3PN3A 1BS5A 3PN4A 1JYMA 3SVJP 4JE6A 3QU1A 5CVPA 4DR9A 1VEVA 1S17A 5CWYA 1WS1A 2KMNA 3FWXA 3K6LA 3L87A 1ZY1A 5JF4A 5JF5A 5JEYA 1RQCA 3U7KA 1BSKA 1V3YA 3G5KA 4WXKA 5JF3A 3CPMA 5J46A 3G5PA 3G6NA 1DEFA 1LRYA 3U7NA 5KOBA 4EOXP 1SZZA 1ZY0A 1BSZA 2EW5A 5JEXA 3O3JA 2DEFA 2EW7A 3PN6A 1ZXZA 1BS8A 4DR8A 5I2BA 5CWXA 5CP0A 1Y6HA 5JEZA 1BS7A 4AL2A 5JF6A 1LMEA 3E3UA 4JE8A 1Q1YA 1WS0A 3STRP 1IX1A 5CXJA 3M6PA 4AL3A 5JF7A 5JF0A 1RL4A 5E5DA 1LQYA 2EW6A 1XENA 5CY8A 2OS0A 2AI9A 2AI7A 1BSJA 5HGWA 1DFFA 3U7LA 5CVKA 3M6QA 5CX0A 5JF1A 2OS3A 1LM6A 3OCAA 2OS1A 4WXLA 4JE7A 2W3TA 3U7MA 3SW8P 3UWAA 1N5NA 1G2AA 3CMDA 1LM4A 1BS6A 4E9BA 3U04A 5T8ZA 5JF2A 2AI8A 2W3UA 5CPDA 4E9AA 3PN2A 2OKLA 4NT8A 5JF8A 1LMHA 1VEYA 4AZ4A 5CY7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1G27 A;  1XEO A;  1ICJ A;  1LQW A;  2AIA A;  3M6O A;  3M6R A;  5CVQ A;  3UWB A;  1VEZ A;  3PN5 A;  1BS4 A;  2AIE P;  1XEM A;  1SV2 A;  1LRU A;  3PN3 A;  1BS5 A;  3PN4 A;  1JYM A;  3SVJ P;  4JE6 A;  3QU1 A;  5CVP A;  4DR9 A;  1VEV A;  1S17 A;  5CWY A;  1WS1 A;  2KMN A;  3FWX A;  3K6L A;  3L87 A;  1ZY1 A;  5JF4 A;  5JF5 A;  5JEY A;  1RQC A;  3U7K A;  1BSK A;  1V3Y A;  3G5K A;  4WXK A;  5JF3 A;  3CPM A;  5J46 A;  3G5P A;  3G6N A;  1DEF A;  1LRY A;  3U7N A;  5KOB A;  4EOX P;  1SZZ A;  1ZY0 A;  1BSZ A;  2EW5 A;  5JEX A;  3O3J A;  2DEF A;  2EW7 A;  3PN6 A;  1ZXZ A;  1BS8 A;  4DR8 A;  5I2B A;  5CWX A;  5CP0 A;  1Y6H A;  5JEZ A;  1BS7 A;  4AL2 A;  5JF6 A;  1LME A;  3E3U A;  4JE8 A;  1Q1Y A;  1WS0 A;  3STR P;  1IX1 A;  5CXJ A;  3M6P A;  4AL3 A;  5JF7 A;  5JF0 A;  1RL4 A;  5E5D A;  1LQY A;  2EW6 A;  1XEN A;  5CY8 A;  2OS0 A;  2AI9 A;  2AI7 A;  1BSJ A;  5HGW A;  1DFF A;  3U7L A;  5CVK A;  3M6Q A;  5CX0 A;  5JF1 A;  2OS3 A;  1LM6 A;  3OCA A;  2OS1 A;  4WXL A;  4JE7 A;  2W3T A;  3U7M A;  3SW8 P;  3UWA A;  1N5N A;  1G2A A;  3CMD A;  1LM4 A;  1BS6 A;  4E9B A;  3U04 A;  5T8Z A;  5JF2 A;  2AI8 A;  2W3U A;  5CPD A;  4E9A A;  3PN2 A;  2OKL A;  4NT8 A;  5JF8 A;  1LMH A;  1VEY A;  4AZ4 A;  5CY7 A; 
#chains in the Genus database with same CATH topology
 1G27 A;  1XEO A;  1ICJ A;  1LQW A;  2AIA A;  3M6O A;  3M6R A;  5CVQ A;  3UWB A;  1VEZ A;  3PN5 A;  1BS4 A;  2AIE P;  1XEM A;  1SV2 A;  1LRU A;  3PN3 A;  1BS5 A;  3PN4 A;  1JYM A;  3SVJ P;  4JE6 A;  3QU1 A;  5CVP A;  4DR9 A;  1VEV A;  1S17 A;  5CWY A;  1WS1 A;  2KMN A;  3FWX A;  3K6L A;  3L87 A;  1ZY1 A;  5JF4 A;  5JF5 A;  5JEY A;  1RQC A;  3U7K A;  1BSK A;  1V3Y A;  3G5K A;  4WXK A;  5JF3 A;  3CPM A;  5J46 A;  3G5P A;  3G6N A;  1DEF A;  1LRY A;  3U7N A;  5KOB A;  4EOX P;  1SZZ A;  1ZY0 A;  1BSZ A;  2EW5 A;  5JEX A;  3O3J A;  2DEF A;  2EW7 A;  3PN6 A;  1ZXZ A;  1BS8 A;  4DR8 A;  5I2B A;  5CWX A;  5CP0 A;  1Y6H A;  5JEZ A;  1BS7 A;  4AL2 A;  5JF6 A;  1LME A;  3E3U A;  4JE8 A;  1Q1Y A;  1WS0 A;  3STR P;  1IX1 A;  5CXJ A;  3M6P A;  4AL3 A;  5JF7 A;  5JF0 A;  1RL4 A;  5E5D A;  1LQY A;  2EW6 A;  1XEN A;  5CY8 A;  2OS0 A;  2AI9 A;  2AI7 A;  1BSJ A;  5HGW A;  1DFF A;  3U7L A;  5CVK A;  3M6Q A;  5CX0 A;  5JF1 A;  2OS3 A;  1LM6 A;  3OCA A;  2OS1 A;  4WXL A;  4JE7 A;  2W3T A;  3U7M A;  3SW8 P;  3UWA A;  1N5N A;  1G2A A;  3CMD A;  1LM4 A;  1BS6 A;  4E9B A;  3U04 A;  5T8Z A;  5JF2 A;  2AI8 A;  2W3U A;  5CPD A;  4E9A A;  3PN2 A;  2OKL A;  4NT8 A;  5JF8 A;  1LMH A;  1VEY A;  4AZ4 A;  5CY7 A; 
#chains in the Genus database with same CATH homology
 1G27 A;  1XEO A;  1ICJ A;  1LQW A;  2AIA A;  3M6O A;  3M6R A;  5CVQ A;  3UWB A;  1VEZ A;  3PN5 A;  1BS4 A;  2AIE P;  1XEM A;  1SV2 A;  1LRU A;  3PN3 A;  1BS5 A;  3PN4 A;  1JYM A;  3SVJ P;  4JE6 A;  3QU1 A;  5CVP A;  4DR9 A;  1VEV A;  1S17 A;  5CWY A;  1WS1 A;  2KMN A;  3FWX A;  3K6L A;  3L87 A;  1ZY1 A;  5JF4 A;  5JF5 A;  5JEY A;  1RQC A;  3U7K A;  1BSK A;  1V3Y A;  3G5K A;  4WXK A;  5JF3 A;  3CPM A;  5J46 A;  3G5P A;  3G6N A;  1DEF A;  1LRY A;  3U7N A;  5KOB A;  4EOX P;  1SZZ A;  1ZY0 A;  1BSZ A;  2EW5 A;  5JEX A;  3O3J A;  2DEF A;  2EW7 A;  3PN6 A;  1ZXZ A;  1BS8 A;  4DR8 A;  5I2B A;  5CWX A;  5CP0 A;  1Y6H A;  5JEZ A;  1BS7 A;  4AL2 A;  5JF6 A;  1LME A;  3E3U A;  4JE8 A;  1Q1Y A;  1WS0 A;  3STR P;  1IX1 A;  5CXJ A;  3M6P A;  4AL3 A;  5JF7 A;  5JF0 A;  1RL4 A;  5E5D A;  1LQY A;  2EW6 A;  1XEN A;  5CY8 A;  2OS0 A;  2AI9 A;  2AI7 A;  1BSJ A;  5HGW A;  1DFF A;  3U7L A;  5CVK A;  3M6Q A;  5CX0 A;  5JF1 A;  2OS3 A;  1LM6 A;  3OCA A;  2OS1 A;  4WXL A;  4JE7 A;  2W3T A;  3U7M A;  3SW8 P;  3UWA A;  1N5N A;  1G2A A;  3CMD A;  1LM4 A;  1BS6 A;  4E9B A;  3U04 A;  5T8Z A;  5JF2 A;  2AI8 A;  2W3U A;  5CPD A;  4E9A A;  3PN2 A;  2OKL A;  4NT8 A;  5JF8 A;  1LMH A;  1VEY A;  4AZ4 A;  5CY7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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