1RN8A

Crystal structure of dutpase complexed with substrate analogue imido-dutp
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
152
structure length
140
Chain Sequence
MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLNDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVWNRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDFRQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Catalytic Mechanism of Phosphate Ester Hydrolysis by dUTPase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Deoxyuridine 5'-triphosphate nucleotidohydrolase
total genus 22
structure length 140
sequence length 152
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2003-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 1rn8A00
2XCDA 3TPSA 3TRLA 3ZEZA 1PKKA 2QLPA 2YZJA 2OL1A 2BT1A 3T64A 2J4HA 1F7QA 3ZF5A 3ZF6A 2J4QA 2QXXA 3TPNA 1XS4A 3ZF2A 1F7RA 5EDDA 4OOPA 3H6DA 3ZF3A 3LOJA 3ZF0A 1SNFA 2PC5A 4OOQA 2OKEA 2ZDCA 1XS6A 2WE0A 4APZ1 3H6XA 1DUNA 4GV8A 1XS1A 1DUDA 3T60A 1OGHA 2WE3A 2BAZA 1DUPA 1PKHA 2XCEA 3LQWA 3TP1A 3TQZA 3C2TA 2D4MA 1DUCA 1VYQA 2D4NA 2V9XA 1EU5A 4DHKA 3TQ3A 1F7KA 2HRMA 3F4FA 4A6AA 3TS6A 2PY4A 5F9KA 2D4LA 2Y1TA 1SIXA 1SLHA 2HQUA 4GK6A 4AOOA 1SJNA 4LHRA 1SMCA 1F7DA 1SEHA 3HHQA 3ARAA 3TSLA 3C3IA 1Q5UX 1SYLA 3GF0A 4XJCA 4AOZA 1EUWA 2XX6A 4WRKA 3TRNA 4GCYA 3T70A 1RN8A 2OKBA 3TPYA 4AO5A 2Y8CA 1F7OA 1F7NA 3CA9A 2WE2A 3EHWA 5CCTA 5ECTA 1Q5HA 1DUTA 1PKJA 2HR6A 3ECYA 1MQ7A 3TTAA 1SM8A 2HXBA 2XY3A 2OKDA 3P48A 3SO2A 3ZF1A 3ARNA 2R9QA 3HZAA 3ZF4A 3T6YA 2OL0A 3I93A 3TQ4A 3MDXA 1F7PA 1RNJA 4B0HA 3MBQA 3TPWA 3KM3A 2BSYA 2WE1A 5CCOA 2HXDA 3TQ5A
chains in the Genus database with same CATH superfamily
2XCDA 3TPSA 3TRLA 3ZEZA 1PKKA 2QLPA 2YZJA 2OL1A 2BT1A 3T64A 2J4HA 1F7QA 3ZF5A 3ZF6A 2J4QA 2QXXA 3TPNA 1XS4A 3ZF2A 1F7RA 5EDDA 4OOPA 3H6DA 3ZF3A 3LOJA 3ZF0A 1SNFA 2PC5A 4OOQA 2OKEA 2ZDCA 1XS6A 2WE0A 4APZ1 3H6XA 1DUNA 4GV8A 1XS1A 1DUDA 3T60A 1OGHA 2WE3A 2BAZA 1DUPA 1PKHA 2XCEA 3LQWA 3TP1A 3TQZA 3C2TA 2D4MA 1DUCA 1VYQA 2D4NA 2V9XA 1TULA 1EU5A 4DHKA 3TQ3A 1F7KA 2HRMA 3F4FA 4A6AA 3TS6A 2PY4A 5F9KA 2D4LA 2Y1TA 1SIXA 1SLHA 2HQUA 4GK6A 4AOOA 1SJNA 4LHRA 1SMCA 1F7DA 1SEHA 3HHQA 3ARAA 3TSLA 3C3IA 1Q5UX 1SYLA 3GF0A 4XJCA 4AOZA 1EUWA 2XX6A 4WRKA 3TRNA 4GCYA 3T70A 1RN8A 2OKBA 3TPYA 4AO5A 2Y8CA 1F7OA 1F7NA 3CA9A 2WE2A 3EHWA 5CCTA 5ECTA 1Q5HA 1DUTA 1PKJA 2HR6A 3ECYA 1MQ7A 3TTAA 1SM8A 2HXBA 2XY3A 2OKDA 3P48A 3SO2A 3ZF1A 3ARNA 2R9QA 3HZAA 3ZF4A 3T6YA 2OL0A 3I93A 3TQ4A 3MDXA 1F7PA 1RNJA 4B0HA 3MBQA 3TPWA 3KM3A 2BSYA 2WE1A 5CCOA 2HXDA 3TQ5A
chains in the Genus database with same CATH topology
2XCDA 3TPSA 3TRLA 3ZEZA 1PKKA 2QLPA 2YZJA 2OL1A 2BT1A 3T64A 2J4HA 1F7QA 3ZF5A 3ZF6A 2J4QA 2QXXA 3TPNA 1XS4A 3ZF2A 1F7RA 5EDDA 4OOPA 3H6DA 3ZF3A 3LOJA 3ZF0A 1SNFA 2PC5A 4OOQA 2OKEA 2ZDCA 1XS6A 2WE0A 4APZ1 3H6XA 1DUNA 4GV8A 1XS1A 1DUDA 3T60A 1OGHA 2WE3A 2BAZA 1DUPA 1PKHA 2XCEA 3LQWA 3TP1A 3TQZA 3C2TA 2D4MA 1DUCA 1VYQA 2D4NA 2V9XA 1EU5A 4DHKA 3TQ3A 1F7KA 2HRMA 3F4FA 4A6AA 3TS6A 2PY4A 5F9KA 2D4LA 2Y1TA 1SIXA 1SLHA 2HQUA 4GK6A 4AOOA 1SJNA 4LHRA 1SMCA 1F7DA 1SEHA 3HHQA 3ARAA 3TSLA 3C3IA 1Q5UX 1SYLA 3GF0A 4XJCA 4AOZA 1EUWA 2XX6A 4WRKA 3TRNA 4GCYA 3T70A 1RN8A 2OKBA 3TPYA 4AO5A 2Y8CA 1F7OA 1F7NA 3CA9A 2WE2A 3EHWA 5CCTA 5ECTA 1Q5HA 1DUTA 1PKJA 2HR6A 3ECYA 1MQ7A 3TTAA 1SM8A 2HXBA 2XY3A 2OKDA 3P48A 3SO2A 3ZF1A 3ARNA 2R9QA 3HZAA 3ZF4A 3T6YA 2OL0A 3I93A 3TQ4A 3MDXA 1F7PA 1RNJA 4B0HA 3MBQA 3TPWA 3KM3A 2BSYA 2WE1A 5CCOA 2HXDA 3TQ5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XCD A;  3TPS A;  3TRL A;  3ZEZ A;  1PKK A;  2QLP A;  2YZJ A;  2OL1 A;  2BT1 A;  3T64 A;  2J4H A;  1F7Q A;  3ZF5 A;  3ZF6 A;  2J4Q A;  2QXX A;  3TPN A;  1XS4 A;  3ZF2 A;  1F7R A;  5EDD A;  4OOP A;  3H6D A;  3ZF3 A;  3LOJ A;  3ZF0 A;  1SNF A;  2PC5 A;  4OOQ A;  2OKE A;  2ZDC A;  1XS6 A;  2WE0 A;  4APZ 1;  3H6X A;  1DUN A;  4GV8 A;  1XS1 A;  1DUD A;  3T60 A;  1OGH A;  2WE3 A;  2BAZ A;  1DUP A;  1PKH A;  2XCE A;  3LQW A;  3TP1 A;  3TQZ A;  3C2T A;  2D4M A;  1DUC A;  1VYQ A;  2D4N A;  2V9X A;  1EU5 A;  4DHK A;  3TQ3 A;  1F7K A;  2HRM A;  3F4F A;  4A6A A;  3TS6 A;  2PY4 A;  5F9K A;  2D4L A;  2Y1T A;  1SIX A;  1SLH A;  2HQU A;  4GK6 A;  4AOO A;  1SJN A;  4LHR A;  1SMC A;  1F7D A;  1SEH A;  3HHQ A;  3ARA A;  3TSL A;  3C3I A;  1Q5U X;  1SYL A;  3GF0 A;  4XJC A;  4AOZ A;  1EUW A;  2XX6 A;  4WRK A;  3TRN A;  4GCY A;  3T70 A;  1RN8 A;  2OKB A;  3TPY A;  4AO5 A;  2Y8C A;  1F7O A;  1F7N A;  3CA9 A;  2WE2 A;  3EHW A;  5CCT A;  5ECT A;  1Q5H A;  1DUT A;  1PKJ A;  2HR6 A;  3ECY A;  1MQ7 A;  3TTA A;  1SM8 A;  2HXB A;  2XY3 A;  2OKD A;  3P48 A;  3SO2 A;  3ZF1 A;  3ARN A;  2R9Q A;  3HZA A;  3ZF4 A;  3T6Y A;  2OL0 A;  3I93 A;  3TQ4 A;  3MDX A;  1F7P A;  1RNJ A;  4B0H A;  3MBQ A;  3TPW A;  3KM3 A;  2BSY A;  2WE1 A;  5CCO A;  2HXD A;  3TQ5 A; 
#chains in the Genus database with same CATH topology
 2XCD A;  3TPS A;  3TRL A;  3ZEZ A;  1PKK A;  2QLP A;  2YZJ A;  2OL1 A;  2BT1 A;  3T64 A;  2J4H A;  1F7Q A;  3ZF5 A;  3ZF6 A;  2J4Q A;  2QXX A;  3TPN A;  1XS4 A;  3ZF2 A;  1F7R A;  5EDD A;  4OOP A;  3H6D A;  3ZF3 A;  3LOJ A;  3ZF0 A;  1SNF A;  2PC5 A;  4OOQ A;  2OKE A;  2ZDC A;  1XS6 A;  2WE0 A;  4APZ 1;  3H6X A;  1DUN A;  4GV8 A;  1XS1 A;  1DUD A;  3T60 A;  1OGH A;  2WE3 A;  2BAZ A;  1DUP A;  1PKH A;  2XCE A;  3LQW A;  3TP1 A;  3TQZ A;  3C2T A;  2D4M A;  1DUC A;  1VYQ A;  2D4N A;  2V9X A;  1TUL A;  1EU5 A;  4DHK A;  3TQ3 A;  1F7K A;  2HRM A;  3F4F A;  4A6A A;  3TS6 A;  2PY4 A;  5F9K A;  2D4L A;  2Y1T A;  1SIX A;  1SLH A;  2HQU A;  4GK6 A;  4AOO A;  1SJN A;  4LHR A;  1SMC A;  1F7D A;  1SEH A;  3HHQ A;  3ARA A;  3TSL A;  3C3I A;  1Q5U X;  1SYL A;  3GF0 A;  4XJC A;  4AOZ A;  1EUW A;  2XX6 A;  4WRK A;  3TRN A;  4GCY A;  3T70 A;  1RN8 A;  2OKB A;  3TPY A;  4AO5 A;  2Y8C A;  1F7O A;  1F7N A;  3CA9 A;  2WE2 A;  3EHW A;  5CCT A;  5ECT A;  1Q5H A;  1DUT A;  1PKJ A;  2HR6 A;  3ECY A;  1MQ7 A;  3TTA A;  1SM8 A;  2HXB A;  2XY3 A;  2OKD A;  3P48 A;  3SO2 A;  3ZF1 A;  3ARN A;  2R9Q A;  3HZA A;  3ZF4 A;  3T6Y A;  2OL0 A;  3I93 A;  3TQ4 A;  3MDX A;  1F7P A;  1RNJ A;  4B0H A;  3MBQ A;  3TPW A;  3KM3 A;  2BSY A;  2WE1 A;  5CCO A;  2HXD A;  3TQ5 A; 
#chains in the Genus database with same CATH homology
 2XCD A;  3TPS A;  3TRL A;  3ZEZ A;  1PKK A;  2QLP A;  2YZJ A;  2OL1 A;  2BT1 A;  3T64 A;  2J4H A;  1F7Q A;  3ZF5 A;  3ZF6 A;  2J4Q A;  2QXX A;  3TPN A;  1XS4 A;  3ZF2 A;  1F7R A;  5EDD A;  4OOP A;  3H6D A;  3ZF3 A;  3LOJ A;  3ZF0 A;  1SNF A;  2PC5 A;  4OOQ A;  2OKE A;  2ZDC A;  1XS6 A;  2WE0 A;  4APZ 1;  3H6X A;  1DUN A;  4GV8 A;  1XS1 A;  1DUD A;  3T60 A;  1OGH A;  2WE3 A;  2BAZ A;  1DUP A;  1PKH A;  2XCE A;  3LQW A;  3TP1 A;  3TQZ A;  3C2T A;  2D4M A;  1DUC A;  1VYQ A;  2D4N A;  2V9X A;  1EU5 A;  4DHK A;  3TQ3 A;  1F7K A;  2HRM A;  3F4F A;  4A6A A;  3TS6 A;  2PY4 A;  5F9K A;  2D4L A;  2Y1T A;  1SIX A;  1SLH A;  2HQU A;  4GK6 A;  4AOO A;  1SJN A;  4LHR A;  1SMC A;  1F7D A;  1SEH A;  3HHQ A;  3ARA A;  3TSL A;  3C3I A;  1Q5U X;  1SYL A;  3GF0 A;  4XJC A;  4AOZ A;  1EUW A;  2XX6 A;  4WRK A;  3TRN A;  4GCY A;  3T70 A;  1RN8 A;  2OKB A;  3TPY A;  4AO5 A;  2Y8C A;  1F7O A;  1F7N A;  3CA9 A;  2WE2 A;  3EHW A;  5CCT A;  5ECT A;  1Q5H A;  1DUT A;  1PKJ A;  2HR6 A;  3ECY A;  1MQ7 A;  3TTA A;  1SM8 A;  2HXB A;  2XY3 A;  2OKD A;  3P48 A;  3SO2 A;  3ZF1 A;  3ARN A;  2R9Q A;  3HZA A;  3ZF4 A;  3T6Y A;  2OL0 A;  3I93 A;  3TQ4 A;  3MDX A;  1F7P A;  1RNJ A;  4B0H A;  3MBQ A;  3TPW A;  3KM3 A;  2BSY A;  2WE1 A;  5CCO A;  2HXD A;  3TQ5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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