1RQCA

Crystals of peptide deformylase from plasmodium falciparum with ten subunits per asymmetric unit reveal critical characteristics of the active site for drug design
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
178
structure length
178
Chain Sequence
KIVKYPDPILRRRSEEVTNFDDNLKRVVRKMFDIMYESKGIGLSAPQVNISKRIIVWNALYEKRKEENERIFINPSIVEQSLVKLKLIEGCLSFPGIEGKVERPSIVSISYYDINGYKHLKILKGIHSRIFQHEFDHLNGTLFIDKMTQVDKKKVRPKLNELIRDYKATHSEEPLEHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title An improved crystal form of Plasmodium falciparum peptide deformylase
pubmed doi rcsb
molecule tags Hydrolase
source organism Plasmodium falciparum
molecule keywords formylmethionine deformylase
total genus 45
structure length 178
sequence length 178
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date 2003-12-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01327 Pep_deformylase Polypeptide deformylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.45.10 Alpha Beta Alpha-Beta Complex Peptide Deformylase Peptide deformylase 1rqcA00
1LQWA 5CPDA 1BS8A 1LM6A 1XEMA 2AI8A 2KMNA 5CVQA 3UWBA 1N5NA 4EOXP 2W3TA 5J46A 3M6OA 4JE6A 1BSKA 1Q1YA 3M6QA 5JF2A 3O3JA 1VEYA 5JF6A 1Y6HA 4WXLA 3UWAA 3STRP 5JEYA 5JF3A 3QU1A 1RL4A 2EW7A 1G27A 3PN2A 3PN4A 5JF1A 2W3UA 3G5KA 1BS7A 1IX1A 2OKLA 4WXKA 5CP0A 3U7NA 2AIEP 4E9AA 2DEFA 3OCAA 5CY8A 4DR8A 4DR9A 1LRYA 5CVKA 1JYMA 1VEVA 2EW5A 3FWXA 3U04A 1ZY1A 5HGWA 4AZ4A 5JF0A 3L87A 4JE8A 1VEZA 1ZXZA 1SZZA 1SV2A 5JF5A 3PN6A 4AL2A 1WS0A 4E9BA 5I2BA 4AL3A 3PN3A 5CWXA 3PN5A 1XENA 5JF8A 3K6LA 5E5DA 5JEXA 5KOBA 1LMHA 1BS5A 3CMDA 3U7KA 3M6RA 1RQCA 3G5PA 1BSZA 1LM4A 1ZY0A 5CWYA 2OS3A 1LMEA 2AI9A 5T8ZA 5JF7A 5CX0A 3SW8P 5CXJA 1DEFA 1G2AA 1V3YA 1BS6A 2EW6A 2AI7A 3E3UA 2OS1A 1LRUA 1S17A 2OS0A 3CPMA 5CY7A 1WS1A 1DFFA 1LQYA 5JEZA 3U7MA 2AIAA 4JE7A 1XEOA 1BSJA 3G6NA 3U7LA 5JF4A 4NT8A 5CVPA 3M6PA 1ICJA 1BS4A 3SVJP
chains in the Genus database with same CATH superfamily
1LQWA 5CPDA 1BS8A 1LM6A 1XEMA 2AI8A 2KMNA 5CVQA 3UWBA 1N5NA 4EOXP 2W3TA 5J46A 3M6OA 4JE6A 1BSKA 1Q1YA 3M6QA 5JF2A 3O3JA 1VEYA 5JF6A 1Y6HA 4WXLA 3UWAA 3STRP 5JEYA 5JF3A 3QU1A 1RL4A 2EW7A 1G27A 3PN2A 3PN4A 5JF1A 2W3UA 3G5KA 1BS7A 1IX1A 2OKLA 4WXKA 5CP0A 3U7NA 2AIEP 4E9AA 2DEFA 3OCAA 5CY8A 4DR8A 4DR9A 1LRYA 5CVKA 1JYMA 1VEVA 2EW5A 3FWXA 3U04A 1ZY1A 5HGWA 4AZ4A 5JF0A 3L87A 4JE8A 1VEZA 1ZXZA 1SZZA 1SV2A 5JF5A 3PN6A 4AL2A 1WS0A 4E9BA 5I2BA 4AL3A 3PN3A 5CWXA 3PN5A 1XENA 5JF8A 3K6LA 5E5DA 5JEXA 5KOBA 1LMHA 1BS5A 3CMDA 3U7KA 3M6RA 1RQCA 3G5PA 1BSZA 1LM4A 1ZY0A 5CWYA 2OS3A 1LMEA 2AI9A 5T8ZA 5JF7A 5CX0A 3SW8P 5CXJA 1DEFA 1G2AA 1V3YA 1BS6A 2EW6A 2AI7A 3E3UA 2OS1A 1LRUA 1S17A 2OS0A 3CPMA 5CY7A 1WS1A 1DFFA 1LQYA 5JEZA 3U7MA 2AIAA 4JE7A 1XEOA 1BSJA 3G6NA 3U7LA 5JF4A 4NT8A 5CVPA 3M6PA 1ICJA 1BS4A 3SVJP
chains in the Genus database with same CATH topology
1LQWA 5CPDA 1BS8A 1LM6A 1XEMA 2AI8A 2KMNA 5CVQA 3UWBA 1N5NA 4EOXP 2W3TA 5J46A 3M6OA 4JE6A 1BSKA 1Q1YA 3M6QA 5JF2A 3O3JA 1VEYA 5JF6A 1Y6HA 4WXLA 3UWAA 3STRP 5JEYA 5JF3A 3QU1A 1RL4A 2EW7A 1G27A 3PN2A 3PN4A 5JF1A 2W3UA 3G5KA 1BS7A 1IX1A 2OKLA 4WXKA 5CP0A 3U7NA 2AIEP 4E9AA 2DEFA 3OCAA 5CY8A 4DR8A 4DR9A 1LRYA 5CVKA 1JYMA 1VEVA 2EW5A 3FWXA 3U04A 1ZY1A 5HGWA 4AZ4A 5JF0A 3L87A 4JE8A 1VEZA 1ZXZA 1SZZA 1SV2A 5JF5A 3PN6A 4AL2A 1WS0A 4E9BA 5I2BA 4AL3A 3PN3A 5CWXA 3PN5A 1XENA 5JF8A 3K6LA 5E5DA 5JEXA 5KOBA 1LMHA 1BS5A 3CMDA 3U7KA 3M6RA 1RQCA 3G5PA 1BSZA 1LM4A 1ZY0A 5CWYA 2OS3A 1LMEA 2AI9A 5T8ZA 5JF7A 5CX0A 3SW8P 5CXJA 1DEFA 1G2AA 1V3YA 1BS6A 2EW6A 2AI7A 3E3UA 2OS1A 1LRUA 1S17A 2OS0A 3CPMA 5CY7A 1WS1A 1DFFA 1LQYA 5JEZA 3U7MA 2AIAA 4JE7A 1XEOA 1BSJA 3G6NA 3U7LA 5JF4A 4NT8A 5CVPA 3M6PA 1ICJA 1BS4A 3SVJP
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LQW A;  5CPD A;  1BS8 A;  1LM6 A;  1XEM A;  2AI8 A;  2KMN A;  5CVQ A;  3UWB A;  1N5N A;  4EOX P;  2W3T A;  5J46 A;  3M6O A;  4JE6 A;  1BSK A;  1Q1Y A;  3M6Q A;  5JF2 A;  3O3J A;  1VEY A;  5JF6 A;  1Y6H A;  4WXL A;  3UWA A;  3STR P;  5JEY A;  5JF3 A;  3QU1 A;  1RL4 A;  2EW7 A;  1G27 A;  3PN2 A;  3PN4 A;  5JF1 A;  2W3U A;  3G5K A;  1BS7 A;  1IX1 A;  2OKL A;  4WXK A;  5CP0 A;  3U7N A;  2AIE P;  4E9A A;  2DEF A;  3OCA A;  5CY8 A;  4DR8 A;  4DR9 A;  1LRY A;  5CVK A;  1JYM A;  1VEV A;  2EW5 A;  3FWX A;  3U04 A;  1ZY1 A;  5HGW A;  4AZ4 A;  5JF0 A;  3L87 A;  4JE8 A;  1VEZ A;  1ZXZ A;  1SZZ A;  1SV2 A;  5JF5 A;  3PN6 A;  4AL2 A;  1WS0 A;  4E9B A;  5I2B A;  4AL3 A;  3PN3 A;  5CWX A;  3PN5 A;  1XEN A;  5JF8 A;  3K6L A;  5E5D A;  5JEX A;  5KOB A;  1LMH A;  1BS5 A;  3CMD A;  3U7K A;  3M6R A;  1RQC A;  3G5P A;  1BSZ A;  1LM4 A;  1ZY0 A;  5CWY A;  2OS3 A;  1LME A;  2AI9 A;  5T8Z A;  5JF7 A;  5CX0 A;  3SW8 P;  5CXJ A;  1DEF A;  1G2A A;  1V3Y A;  1BS6 A;  2EW6 A;  2AI7 A;  3E3U A;  2OS1 A;  1LRU A;  1S17 A;  2OS0 A;  3CPM A;  5CY7 A;  1WS1 A;  1DFF A;  1LQY A;  5JEZ A;  3U7M A;  2AIA A;  4JE7 A;  1XEO A;  1BSJ A;  3G6N A;  3U7L A;  5JF4 A;  4NT8 A;  5CVP A;  3M6P A;  1ICJ A;  1BS4 A;  3SVJ P; 
#chains in the Genus database with same CATH topology
 1LQW A;  5CPD A;  1BS8 A;  1LM6 A;  1XEM A;  2AI8 A;  2KMN A;  5CVQ A;  3UWB A;  1N5N A;  4EOX P;  2W3T A;  5J46 A;  3M6O A;  4JE6 A;  1BSK A;  1Q1Y A;  3M6Q A;  5JF2 A;  3O3J A;  1VEY A;  5JF6 A;  1Y6H A;  4WXL A;  3UWA A;  3STR P;  5JEY A;  5JF3 A;  3QU1 A;  1RL4 A;  2EW7 A;  1G27 A;  3PN2 A;  3PN4 A;  5JF1 A;  2W3U A;  3G5K A;  1BS7 A;  1IX1 A;  2OKL A;  4WXK A;  5CP0 A;  3U7N A;  2AIE P;  4E9A A;  2DEF A;  3OCA A;  5CY8 A;  4DR8 A;  4DR9 A;  1LRY A;  5CVK A;  1JYM A;  1VEV A;  2EW5 A;  3FWX A;  3U04 A;  1ZY1 A;  5HGW A;  4AZ4 A;  5JF0 A;  3L87 A;  4JE8 A;  1VEZ A;  1ZXZ A;  1SZZ A;  1SV2 A;  5JF5 A;  3PN6 A;  4AL2 A;  1WS0 A;  4E9B A;  5I2B A;  4AL3 A;  3PN3 A;  5CWX A;  3PN5 A;  1XEN A;  5JF8 A;  3K6L A;  5E5D A;  5JEX A;  5KOB A;  1LMH A;  1BS5 A;  3CMD A;  3U7K A;  3M6R A;  1RQC A;  3G5P A;  1BSZ A;  1LM4 A;  1ZY0 A;  5CWY A;  2OS3 A;  1LME A;  2AI9 A;  5T8Z A;  5JF7 A;  5CX0 A;  3SW8 P;  5CXJ A;  1DEF A;  1G2A A;  1V3Y A;  1BS6 A;  2EW6 A;  2AI7 A;  3E3U A;  2OS1 A;  1LRU A;  1S17 A;  2OS0 A;  3CPM A;  5CY7 A;  1WS1 A;  1DFF A;  1LQY A;  5JEZ A;  3U7M A;  2AIA A;  4JE7 A;  1XEO A;  1BSJ A;  3G6N A;  3U7L A;  5JF4 A;  4NT8 A;  5CVP A;  3M6P A;  1ICJ A;  1BS4 A;  3SVJ P; 
#chains in the Genus database with same CATH homology
 1LQW A;  5CPD A;  1BS8 A;  1LM6 A;  1XEM A;  2AI8 A;  2KMN A;  5CVQ A;  3UWB A;  1N5N A;  4EOX P;  2W3T A;  5J46 A;  3M6O A;  4JE6 A;  1BSK A;  1Q1Y A;  3M6Q A;  5JF2 A;  3O3J A;  1VEY A;  5JF6 A;  1Y6H A;  4WXL A;  3UWA A;  3STR P;  5JEY A;  5JF3 A;  3QU1 A;  1RL4 A;  2EW7 A;  1G27 A;  3PN2 A;  3PN4 A;  5JF1 A;  2W3U A;  3G5K A;  1BS7 A;  1IX1 A;  2OKL A;  4WXK A;  5CP0 A;  3U7N A;  2AIE P;  4E9A A;  2DEF A;  3OCA A;  5CY8 A;  4DR8 A;  4DR9 A;  1LRY A;  5CVK A;  1JYM A;  1VEV A;  2EW5 A;  3FWX A;  3U04 A;  1ZY1 A;  5HGW A;  4AZ4 A;  5JF0 A;  3L87 A;  4JE8 A;  1VEZ A;  1ZXZ A;  1SZZ A;  1SV2 A;  5JF5 A;  3PN6 A;  4AL2 A;  1WS0 A;  4E9B A;  5I2B A;  4AL3 A;  3PN3 A;  5CWX A;  3PN5 A;  1XEN A;  5JF8 A;  3K6L A;  5E5D A;  5JEX A;  5KOB A;  1LMH A;  1BS5 A;  3CMD A;  3U7K A;  3M6R A;  1RQC A;  3G5P A;  1BSZ A;  1LM4 A;  1ZY0 A;  5CWY A;  2OS3 A;  1LME A;  2AI9 A;  5T8Z A;  5JF7 A;  5CX0 A;  3SW8 P;  5CXJ A;  1DEF A;  1G2A A;  1V3Y A;  1BS6 A;  2EW6 A;  2AI7 A;  3E3U A;  2OS1 A;  1LRU A;  1S17 A;  2OS0 A;  3CPM A;  5CY7 A;  1WS1 A;  1DFF A;  1LQY A;  5JEZ A;  3U7M A;  2AIA A;  4JE7 A;  1XEO A;  1BSJ A;  3G6N A;  3U7L A;  5JF4 A;  4NT8 A;  5CVP A;  3M6P A;  1ICJ A;  1BS4 A;  3SVJ P; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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