1UJZB

Crystal structure of the e7_c/im7_c complex; a computationally designed interface between the colicin e7 dnase and the im7 immunity protein
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
127
structure length
127
Chain Sequence
RNKPGKATGKGKPVNNKWLNNAGKDLGSPVPDRIANKLRDKEFKSFDDFRKKFWEEVSKDPELSKQFSRNNNDRMKVGKAPQTRTQDVSGKRRSFELHHEKPISQNGGVYDMDNISVVTPKRAIDIH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Computational redesign of protein-protein interaction specificity
pubmed doi rcsb
molecule tags Immune system
source organism Escherichia coli
molecule keywords Designed Colicin E7 immunity protein
total genus 35
structure length 127
sequence length 127
ec nomenclature ec 3.1.-.-:
pdb deposition date 2003-08-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.540.10 Alpha Beta Alpha-Beta Complex Colicin E7 immunity protein; Chain B, fragment: Endonuclease domain Colicin/pyocin, DNase domain 1ujzB00
1FR2B 3FBDA 2GZFB 2VLPB 3ZFKA 1V14A 1UJZB 3GJNB 4QKOB 4UHPA 1MZ8B 2VLNB 7CEIB 2VLOB 2JAZB 1ZNVB 2ERHB 3U43B 1PT3A 2IVHA 2GZIB 1V13A 1FSJB 1BXIB 2VLQB 4UHQA 1V15A 1M08A 2GYKB 2GZJB 2K5XB 2GZEB 2GZGB 3GKLA 2WPTB 1EMVB 1ZNSA 2JB0B 2JBGB
chains in the Genus database with same CATH superfamily
1FR2B 3FBDA 2GZFB 2VLPB 3ZFKA 1V14A 1UJZB 3GJNB 4QKOB 4UHPA 1MZ8B 2VLNB 7CEIB 2VLOB 2JAZB 1ZNVB 2ERHB 3U43B 1PT3A 2IVHA 2GZIB 1V13A 1FSJB 1BXIB 2VLQB 4UHQA 1V15A 1M08A 2GYKB 2GZJB 2K5XB 2GZEB 2GZGB 3GKLA 2WPTB 1EMVB 1ZNSA 2JB0B 2JBGB
chains in the Genus database with same CATH topology
1FR2B 3FBDA 2GZFB 2VLPB 3ZFKA 1V14A 1UJZB 3GJNB 4QKOB 4UHPA 1MZ8B 2VLNB 7CEIB 2VLOB 2JAZB 1ZNVB 2ERHB 3U43B 1PT3A 2IVHA 2GZIB 1V13A 1FSJB 1BXIB 2VLQB 4UHQA 1V15A 1M08A 2GYKB 2GZJB 2K5XB 2GZEB 2GZGB 3GKLA 2WPTB 1EMVB 1ZNSA 2JB0B 2JBGB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FR2 B;  3FBD A;  2GZF B;  2VLP B;  3ZFK A;  1V14 A;  1UJZ B;  3GJN B;  4QKO B;  4UHP A;  1MZ8 B;  2VLN B;  7CEI B;  2VLO B;  2JAZ B;  1ZNV B;  2ERH B;  3U43 B;  1PT3 A;  2IVH A;  2GZI B;  1V13 A;  1FSJ B;  1BXI B;  2VLQ B;  4UHQ A;  1V15 A;  1M08 A;  2GYK B;  2GZJ B;  2K5X B;  2GZE B;  2GZG B;  3GKL A;  2WPT B;  1EMV B;  1ZNS A;  2JB0 B;  2JBG B; 
#chains in the Genus database with same CATH topology
 1FR2 B;  3FBD A;  2GZF B;  2VLP B;  3ZFK A;  1V14 A;  1UJZ B;  3GJN B;  4QKO B;  4UHP A;  1MZ8 B;  2VLN B;  7CEI B;  2VLO B;  2JAZ B;  1ZNV B;  2ERH B;  3U43 B;  1PT3 A;  2IVH A;  2GZI B;  1V13 A;  1FSJ B;  1BXI B;  2VLQ B;  4UHQ A;  1V15 A;  1M08 A;  2GYK B;  2GZJ B;  2K5X B;  2GZE B;  2GZG B;  3GKL A;  2WPT B;  1EMV B;  1ZNS A;  2JB0 B;  2JBG B; 
#chains in the Genus database with same CATH homology
 1FR2 B;  3FBD A;  2GZF B;  2VLP B;  3ZFK A;  1V14 A;  1UJZ B;  3GJN B;  4QKO B;  4UHP A;  1MZ8 B;  2VLN B;  7CEI B;  2VLO B;  2JAZ B;  1ZNV B;  2ERH B;  3U43 B;  1PT3 A;  2IVH A;  2GZI B;  1V13 A;  1FSJ B;  1BXI B;  2VLQ B;  4UHQ A;  1V15 A;  1M08 A;  2GYK B;  2GZJ B;  2K5X B;  2GZE B;  2GZG B;  3GKL A;  2WPT B;  1EMV B;  1ZNS A;  2JB0 B;  2JBG B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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