1VGJA

Crystal structure of 2'-5' rna ligase from pyrococcus horikoshii
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
184
structure length
184
Chain Sequence
MRAFIAIDVNESVRDSLVRAQDYIGSKEAKIKFVERENLHITLKFLGEITEEQAEEIKNILKKIAEKYKKHEVKVKGIGVFPNPNYIRVIWAGIENDEIIREMAREIEDELAKLGFKKEGNFVAHITLGRVKFVKDKLGLTMKLKELANEDFGSFVVDAIELKKSTLTPKGPIYETLARFELSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of Pyrococcus horikoshii 2'-5' RNA ligase at 1.94 A resolution reveals a possible open form with a wider active-site cleft
pubmed doi rcsb
molecule tags Ligase
source organism Pyrococcus horikoshii
molecule keywords Hypothetical protein PH0099
total genus 53
structure length 184
sequence length 184
ec nomenclature ec 3.1.4.58: RNA 2',3'-cyclic 3'-phosphodiesterase.
pdb deposition date 2004-04-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02834 LigT_PEase LigT like Phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1140.10 Alpha Beta Alpha-Beta Complex Cyclic Phosphodiesterase; Chain: A, Cyclic phosphodiesterase 1vgjA00
5JJ2A 5LDOA 5LDKA 2VFYA 2VFKA 5LDIA 5LDMA 1JH6A 1IUHA 1VDXA 1JH7A 4H7WA 2D4GA 5LDPA 5LDJA 1FSIA 2FYHA 1VGJA 2FSQA 4QAKA 2VFLA 5LDQA
chains in the Genus database with same CATH superfamily
5JJ2A 5LDOA 5LDKA 2VFYA 2VFKA 5LDIA 5LDMA 1JH6A 1IUHA 1VDXA 1JH7A 4H7WA 2D4GA 5LDPA 5LDJA 1FSIA 2FYHA 1VGJA 2FSQA 4QAKA 2VFLA 5LDQA
chains in the Genus database with same CATH topology
5JJ2A 5LDOA 5LDKA 2VFYA 2VFKA 5LDIA 5LDMA 1JH6A 1IUHA 1VDXA 1JH7A 4H7WA 2D4GA 5LDPA 5LDJA 1FSIA 2FYHA 1VGJA 2FSQA 4QAKA 2VFLA 5LDQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JJ2 A;  5LDO A;  5LDK A;  2VFY A;  2VFK A;  5LDI A;  5LDM A;  1JH6 A;  1IUH A;  1VDX A;  1JH7 A;  4H7W A;  2D4G A;  5LDP A;  5LDJ A;  1FSI A;  2FYH A;  1VGJ A;  2FSQ A;  4QAK A;  2VFL A;  5LDQ A; 
#chains in the Genus database with same CATH topology
 5JJ2 A;  5LDO A;  5LDK A;  2VFY A;  2VFK A;  5LDI A;  5LDM A;  1JH6 A;  1IUH A;  1VDX A;  1JH7 A;  4H7W A;  2D4G A;  5LDP A;  5LDJ A;  1FSI A;  2FYH A;  1VGJ A;  2FSQ A;  4QAK A;  2VFL A;  5LDQ A; 
#chains in the Genus database with same CATH homology
 5JJ2 A;  5LDO A;  5LDK A;  2VFY A;  2VFK A;  5LDI A;  5LDM A;  1JH6 A;  1IUH A;  1VDX A;  1JH7 A;  4H7W A;  2D4G A;  5LDP A;  5LDJ A;  1FSI A;  2FYH A;  1VGJ A;  2FSQ A;  4QAK A;  2VFL A;  5LDQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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