1XOZA

Catalytic domain of human phosphodiesterase 5a in complex with tadalafil
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
326
structure length
326
Chain Sequence
EEETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHPGVSNQFLINTNSELALMYNDESVLEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
source organism Homo sapiens
publication title Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases.
pubmed doi rcsb
molecule keywords cGMP-specific 3',5'-cyclic phosphodiesterase
total genus 137
structure length 326
sequence length 326
ec nomenclature ec 3.1.4.35: 3',5'-cyclic-GMP phosphodiesterase.
pdb deposition date 2004-10-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00233 PDEase_I 3'5'-cyclic nucleotide phosphodiesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1300.10 Mainly Alpha Orthogonal Bundle Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain 1xozA00
3LXGA 1XMYA 1Y2HA 4AJGA 3G45A 3TGGA 3SL3A 4OGBA 3SNLA 4MSEA 1UHOA 3O0JA 5B25A 5B4LA 1XOSA 3DYLA 3KKTA 3QPOA 3FRGA 1XONA 4LM1A 4G2LA 4LLJA 3SHZA 3WI2A 4HTXA 4NPWA 4AELA 5K1IA 1XM4B 1Q9MA 4YS7A 4MD6A 3HDZA 4D08A 3HR1A 2OVYA 3GWTA 1XMUA 3HQYA 1ZKLA 3WS9A 5C2HA 4LM0A 4PM0A 4E90A 4HTZA 1RO9A 4OEXA 3V94A 2OURA 2HD1A 5K9RA 4JIBA 2FM5A 4Y8CA 3SL4A 3DYSA 4TPPA 1UDUA 3WS8A 4MRZA 4Y86A 3G4KA 4HEUA 4WZIA 2FM0A 5EDHA 5K32A 1Y2BA 3ITUA 3D3PA 4W1OA 5C29A 3LY2A 4I15A 2OUNA 1XMYB 4PHLA 1OYNA 2QYNA 1ZKNA 3IADA 4MSAA 4P1RA 3K3HA 3JSIA 4LM2A 4AJDA 4DDLA 3O56A 4LKQA 1Y2EA 3WYMA 1TB7A 3ITMA 4G2YA 5C2AA 4ZO5A 3DY8A 1RKPA 3G58A 3HMVA 5B4KA 3I8VA 2H42A 2QYMA 1XMUB 3K3EA 4BBXA 1T9SA 1RORA 4MS0A 4YQHA 1SOJA 3WYLA 5EDEA 3SL8A 1UDTA 2OUYA 4DFFA 4KP6A 4AJMA 4PHWA 5AXPA 3SL5A 1F0JA 4IA0A 3DYNA 2OUQA 3SIEA 3QI3A 5DH4A 3HQWA 4MUWA 4MSCA 3QI4A 4X0FA 3SNIA 1TBBA 2CHMA 4WN1A 1SO2A 3JWRA 4Y87A 4P0NA 4AJFA 4OEWA 3TGEA 5C1WA 4NPVA 2QYLA 2OUVA 1RO6A 4FCDA 1Y2CA 4WCUA 3ECMA 3SN7A 5C28A 1TB5A 4G2JA 2OUSA 1Y2DA 4MVHA 3JSWA 3W5EA 1MKDA 4D09A 4G2WA 4Y2BA 3G3NA 3V9BA 4I9ZA 2QYKA 3UI7A 1XP0A 3G4LA 1TBFA 3DYQA 3JWQA 3QPNA 1T9RA 1TAZA 1XOZA 1Y2JA 2WEYA 4TPMA 5EDGA 2PW3A 4MSNA 3BJCA 5EDEB 4C1IA 4NW7A 1Y2KA 5C2EA 3TVXA 4MRWA 1XLZA 4GH6A 4MSHA 1XORA 4LM3A 5EDIA 5EDIB 3SHYA 4LLKA 1XLXA 3WYKA 4QGEA 3IAKA 3N3ZA 5I2RA 2YY2A 1XM4A 1XOTA 3G4GA 2Y0JA 2OUPA 4MYQA 4LM4A 5DH5A 2H44A 2R8QA 2OVVA 3IBJA 5AXQA 2O8HA 3UUOA 1PTWA 4HF4A 3ECNA 3WD9A 1XN0A 3V93A 4XY2A 2H40A 3G4IA 3HQZA 4LLXA 4FCBA 3HC8A 3O57A 3SL6A 1XM6A 2OUUA 1Z1LA 4LLPA 1XOQA 5EDGB 3B2RA 3K4SA 1XOMA 3QPPA
chains in the Genus database with same CATH superfamily
3LXGA 1XMYA 1Y2HA 4AJGA 3G45A 3TGGA 3SL3A 4OGBA 3SNLA 4MSEA 1UHOA 3O0JA 5B25A 5B4LA 1XOSA 3DYLA 3KKTA 3QPOA 3FRGA 1XONA 4LM1A 4G2LA 4LLJA 3SHZA 3WI2A 4HTXA 4NPWA 4AELA 5K1IA 1XM4B 1Q9MA 4YS7A 4MD6A 3HDZA 4D08A 3HR1A 2OVYA 3GWTA 1XMUA 3HQYA 1ZKLA 3WS9A 5C2HA 4LM0A 4PM0A 4E90A 4HTZA 1RO9A 4OEXA 3V94A 2OURA 2HD1A 5K9RA 4JIBA 2FM5A 4Y8CA 3SL4A 3DYSA 4TPPA 1UDUA 3WS8A 4MRZA 4Y86A 3G4KA 4HEUA 4WZIA 2FM0A 5EDHA 5K32A 1Y2BA 3ITUA 3D3PA 4W1OA 5C29A 3LY2A 4I15A 2OUNA 1XMYB 4PHLA 1OYNA 2QYNA 1ZKNA 3IADA 4MSAA 4P1RA 3K3HA 3JSIA 4LM2A 4AJDA 4DDLA 3O56A 4LKQA 1Y2EA 3WYMA 1TB7A 3ITMA 4G2YA 5C2AA 4ZO5A 3DY8A 1RKPA 3G58A 3HMVA 5B4KA 3I8VA 2H42A 2QYMA 1XMUB 3K3EA 4BBXA 1T9SA 1RORA 4MS0A 4YQHA 1SOJA 3WYLA 5EDEA 3SL8A 1UDTA 2OUYA 4DFFA 4KP6A 4AJMA 4PHWA 5AXPA 3SL5A 1F0JA 4IA0A 3DYNA 2OUQA 3SIEA 3QI3A 5DH4A 3HQWA 4MUWA 4MSCA 3QI4A 4X0FA 3SNIA 1TBBA 2CHMA 4WN1A 1SO2A 3JWRA 4Y87A 4P0NA 4AJFA 4OEWA 3TGEA 5C1WA 4NPVA 2QYLA 2OUVA 1RO6A 4FCDA 1Y2CA 4WCUA 3ECMA 3SN7A 5C28A 1TB5A 4G2JA 2OUSA 1Y2DA 4MVHA 3JSWA 3W5EA 1MKDA 4D09A 4G2WA 4Y2BA 3G3NA 3V9BA 4I9ZA 2QYKA 3UI7A 1XP0A 3G4LA 1TBFA 3DYQA 3JWQA 3QPNA 1T9RA 1TAZA 1XOZA 1Y2JA 2WEYA 4TPMA 5EDGA 2PW3A 4MSNA 3BJCA 5EDEB 4C1IA 4NW7A 1Y2KA 5C2EA 3TVXA 4MRWA 1XLZA 4GH6A 4MSHA 1XORA 4LM3A 5EDIA 5EDIB 3SHYA 4LLKA 1XLXA 3WYKA 4QGEA 3IAKA 3N3ZA 5I2RA 2YY2A 1XM4A 1XOTA 3G4GA 2Y0JA 2OUPA 4MYQA 4LM4A 5DH5A 2H44A 2R8QA 2OVVA 3IBJA 5AXQA 2O8HA 3UUOA 1PTWA 4HF4A 3ECNA 3WD9A 1XN0A 3V93A 4XY2A 2H40A 3G4IA 3HQZA 4LLXA 4FCBA 3HC8A 3O57A 3SL6A 1XM6A 2OUUA 1Z1LA 4LLPA 1XOQA 5EDGB 3B2RA 3K4SA 1XOMA 3QPPA
chains in the Genus database with same CATH topology
3LXGA 1XMYA 1Y2HA 4AJGA 3G45A 3TGGA 3SL3A 4OGBA 3SNLA 4MSEA 1UHOA 3O0JA 5B25A 5B4LA 1XOSA 3DYLA 3KKTA 3QPOA 3FRGA 1XONA 4LM1A 4G2LA 4LLJA 3SHZA 3WI2A 4HTXA 4NPWA 4AELA 5K1IA 1XM4B 1Q9MA 4YS7A 4MD6A 3HDZA 4D08A 3HR1A 2OVYA 3GWTA 1XMUA 3HQYA 1ZKLA 3WS9A 5C2HA 4LM0A 4PM0A 4E90A 4HTZA 1RO9A 4OEXA 3V94A 2OURA 2HD1A 5K9RA 4JIBA 2FM5A 4Y8CA 3SL4A 3DYSA 4TPPA 1UDUA 3WS8A 4MRZA 4Y86A 3G4KA 4HEUA 4WZIA 2FM0A 5EDHA 5K32A 1Y2BA 3ITUA 3D3PA 4W1OA 5C29A 3LY2A 4I15A 2OUNA 1XMYB 4PHLA 1OYNA 2QYNA 1ZKNA 3IADA 4MSAA 4P1RA 3K3HA 3JSIA 4LM2A 4AJDA 4DDLA 3O56A 4LKQA 1Y2EA 3WYMA 1TB7A 3ITMA 4G2YA 5C2AA 4ZO5A 3DY8A 1RKPA 3G58A 3HMVA 5B4KA 3I8VA 2H42A 2QYMA 1XMUB 3K3EA 4BBXA 1T9SA 1RORA 4MS0A 4YQHA 1SOJA 3WYLA 5EDEA 3SL8A 1UDTA 2OUYA 4DFFA 4KP6A 4AJMA 4PHWA 5AXPA 3SL5A 1F0JA 4IA0A 3DYNA 2OUQA 3SIEA 3QI3A 5DH4A 3HQWA 4MUWA 4MSCA 3QI4A 4X0FA 3SNIA 1TBBA 2CHMA 4WN1A 1SO2A 3JWRA 4Y87A 4P0NA 4AJFA 4OEWA 3TGEA 5C1WA 4NPVA 2QYLA 2OUVA 1RO6A 4FCDA 1Y2CA 4WCUA 3ECMA 3SN7A 5C28A 1TB5A 4G2JA 2OUSA 1Y2DA 4MVHA 3JSWA 3W5EA 1MKDA 4D09A 4G2WA 4Y2BA 3G3NA 3V9BA 4I9ZA 2QYKA 3UI7A 1XP0A 3G4LA 1TBFA 3DYQA 3JWQA 3QPNA 1T9RA 1TAZA 1XOZA 1Y2JA 2WEYA 4TPMA 5EDGA 2PW3A 4MSNA 3BJCA 5EDEB 4C1IA 4NW7A 1Y2KA 5C2EA 3TVXA 4MRWA 1XLZA 4GH6A 4MSHA 1XORA 4LM3A 5EDIA 5EDIB 3SHYA 4LLKA 1XLXA 3WYKA 4QGEA 3IAKA 3N3ZA 5I2RA 2YY2A 1XM4A 1XOTA 3G4GA 2Y0JA 2OUPA 4MYQA 4LM4A 5DH5A 2H44A 2R8QA 2OVVA 3IBJA 5AXQA 2O8HA 3UUOA 1PTWA 4HF4A 3ECNA 3WD9A 1XN0A 3V93A 4XY2A 2H40A 3G4IA 3HQZA 4LLXA 4FCBA 3HC8A 3O57A 3SL6A 1XM6A 2OUUA 1Z1LA 4LLPA 1XOQA 5EDGB 3B2RA 3K4SA 1XOMA 3QPPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LXG A;  1XMY A;  1Y2H A;  4AJG A;  3G45 A;  3TGG A;  3SL3 A;  4OGB A;  3SNL A;  4MSE A;  1UHO A;  3O0J A;  5B25 A;  5B4L A;  1XOS A;  3DYL A;  3KKT A;  3QPO A;  3FRG A;  1XON A;  4LM1 A;  4G2L A;  4LLJ A;  3SHZ A;  3WI2 A;  4HTX A;  4NPW A;  4AEL A;  5K1I A;  1XM4 B;  1Q9M A;  4YS7 A;  4MD6 A;  3HDZ A;  4D08 A;  3HR1 A;  2OVY A;  3GWT A;  1XMU A;  3HQY A;  1ZKL A;  3WS9 A;  5C2H A;  4LM0 A;  4PM0 A;  4E90 A;  4HTZ A;  1RO9 A;  4OEX A;  3V94 A;  2OUR A;  2HD1 A;  5K9R A;  4JIB A;  2FM5 A;  4Y8C A;  3SL4 A;  3DYS A;  4TPP A;  1UDU A;  3WS8 A;  4MRZ A;  4Y86 A;  3G4K A;  4HEU A;  4WZI A;  2FM0 A;  5EDH A;  5K32 A;  1Y2B A;  3ITU A;  3D3P A;  4W1O A;  5C29 A;  3LY2 A;  4I15 A;  2OUN A;  1XMY B;  4PHL A;  1OYN A;  2QYN A;  1ZKN A;  3IAD A;  4MSA A;  4P1R A;  3K3H A;  3JSI A;  4LM2 A;  4AJD A;  4DDL A;  3O56 A;  4LKQ A;  1Y2E A;  3WYM A;  1TB7 A;  3ITM A;  4G2Y A;  5C2A A;  4ZO5 A;  3DY8 A;  1RKP A;  3G58 A;  3HMV A;  5B4K A;  3I8V A;  2H42 A;  2QYM A;  1XMU B;  3K3E A;  4BBX A;  1T9S A;  1ROR A;  4MS0 A;  4YQH A;  1SOJ A;  3WYL A;  5EDE A;  3SL8 A;  1UDT A;  2OUY A;  4DFF A;  4KP6 A;  4AJM A;  4PHW A;  5AXP A;  3SL5 A;  1F0J A;  4IA0 A;  3DYN A;  2OUQ A;  3SIE A;  3QI3 A;  5DH4 A;  3HQW A;  4MUW A;  4MSC A;  3QI4 A;  4X0F A;  3SNI A;  1TBB A;  2CHM A;  4WN1 A;  1SO2 A;  3JWR A;  4Y87 A;  4P0N A;  4AJF A;  4OEW A;  3TGE A;  5C1W A;  4NPV A;  2QYL A;  2OUV A;  1RO6 A;  4FCD A;  1Y2C A;  4WCU A;  3ECM A;  3SN7 A;  5C28 A;  1TB5 A;  4G2J A;  2OUS A;  1Y2D A;  4MVH A;  3JSW A;  3W5E A;  1MKD A;  4D09 A;  4G2W A;  4Y2B A;  3G3N A;  3V9B A;  4I9Z A;  2QYK A;  3UI7 A;  1XP0 A;  3G4L A;  1TBF A;  3DYQ A;  3JWQ A;  3QPN A;  1T9R A;  1TAZ A;  1XOZ A;  1Y2J A;  2WEY A;  4TPM A;  5EDG A;  2PW3 A;  4MSN A;  3BJC A;  5EDE B;  4C1I A;  4NW7 A;  1Y2K A;  5C2E A;  3TVX A;  4MRW A;  1XLZ A;  4GH6 A;  4MSH A;  1XOR A;  4LM3 A;  5EDI A;  5EDI B;  3SHY A;  4LLK A;  1XLX A;  3WYK A;  4QGE A;  3IAK A;  3N3Z A;  5I2R A;  2YY2 A;  1XM4 A;  1XOT A;  3G4G A;  2Y0J A;  2OUP A;  4MYQ A;  4LM4 A;  5DH5 A;  2H44 A;  2R8Q A;  2OVV A;  3IBJ A;  5AXQ A;  2O8H A;  3UUO A;  1PTW A;  4HF4 A;  3ECN A;  3WD9 A;  1XN0 A;  3V93 A;  4XY2 A;  2H40 A;  3G4I A;  3HQZ A;  4LLX A;  4FCB A;  3HC8 A;  3O57 A;  3SL6 A;  1XM6 A;  2OUU A;  1Z1L A;  4LLP A;  1XOQ A;  5EDG B;  3B2R A;  3K4S A;  1XOM A;  3QPP A; 
#chains in the Genus database with same CATH topology
 3LXG A;  1XMY A;  1Y2H A;  4AJG A;  3G45 A;  3TGG A;  3SL3 A;  4OGB A;  3SNL A;  4MSE A;  1UHO A;  3O0J A;  5B25 A;  5B4L A;  1XOS A;  3DYL A;  3KKT A;  3QPO A;  3FRG A;  1XON A;  4LM1 A;  4G2L A;  4LLJ A;  3SHZ A;  3WI2 A;  4HTX A;  4NPW A;  4AEL A;  5K1I A;  1XM4 B;  1Q9M A;  4YS7 A;  4MD6 A;  3HDZ A;  4D08 A;  3HR1 A;  2OVY A;  3GWT A;  1XMU A;  3HQY A;  1ZKL A;  3WS9 A;  5C2H A;  4LM0 A;  4PM0 A;  4E90 A;  4HTZ A;  1RO9 A;  4OEX A;  3V94 A;  2OUR A;  2HD1 A;  5K9R A;  4JIB A;  2FM5 A;  4Y8C A;  3SL4 A;  3DYS A;  4TPP A;  1UDU A;  3WS8 A;  4MRZ A;  4Y86 A;  3G4K A;  4HEU A;  4WZI A;  2FM0 A;  5EDH A;  5K32 A;  1Y2B A;  3ITU A;  3D3P A;  4W1O A;  5C29 A;  3LY2 A;  4I15 A;  2OUN A;  1XMY B;  4PHL A;  1OYN A;  2QYN A;  1ZKN A;  3IAD A;  4MSA A;  4P1R A;  3K3H A;  3JSI A;  4LM2 A;  4AJD A;  4DDL A;  3O56 A;  4LKQ A;  1Y2E A;  3WYM A;  1TB7 A;  3ITM A;  4G2Y A;  5C2A A;  4ZO5 A;  3DY8 A;  1RKP A;  3G58 A;  3HMV A;  5B4K A;  3I8V A;  2H42 A;  2QYM A;  1XMU B;  3K3E A;  4BBX A;  1T9S A;  1ROR A;  4MS0 A;  4YQH A;  1SOJ A;  3WYL A;  5EDE A;  3SL8 A;  1UDT A;  2OUY A;  4DFF A;  4KP6 A;  4AJM A;  4PHW A;  5AXP A;  3SL5 A;  1F0J A;  4IA0 A;  3DYN A;  2OUQ A;  3SIE A;  3QI3 A;  5DH4 A;  3HQW A;  4MUW A;  4MSC A;  3QI4 A;  4X0F A;  3SNI A;  1TBB A;  2CHM A;  4WN1 A;  1SO2 A;  3JWR A;  4Y87 A;  4P0N A;  4AJF A;  4OEW A;  3TGE A;  5C1W A;  4NPV A;  2QYL A;  2OUV A;  1RO6 A;  4FCD A;  1Y2C A;  4WCU A;  3ECM A;  3SN7 A;  5C28 A;  1TB5 A;  4G2J A;  2OUS A;  1Y2D A;  4MVH A;  3JSW A;  3W5E A;  1MKD A;  4D09 A;  4G2W A;  4Y2B A;  3G3N A;  3V9B A;  4I9Z A;  2QYK A;  3UI7 A;  1XP0 A;  3G4L A;  1TBF A;  3DYQ A;  3JWQ A;  3QPN A;  1T9R A;  1TAZ A;  1XOZ A;  1Y2J A;  2WEY A;  4TPM A;  5EDG A;  2PW3 A;  4MSN A;  3BJC A;  5EDE B;  4C1I A;  4NW7 A;  1Y2K A;  5C2E A;  3TVX A;  4MRW A;  1XLZ A;  4GH6 A;  4MSH A;  1XOR A;  4LM3 A;  5EDI A;  5EDI B;  3SHY A;  4LLK A;  1XLX A;  3WYK A;  4QGE A;  3IAK A;  3N3Z A;  5I2R A;  2YY2 A;  1XM4 A;  1XOT A;  3G4G A;  2Y0J A;  2OUP A;  4MYQ A;  4LM4 A;  5DH5 A;  2H44 A;  2R8Q A;  2OVV A;  3IBJ A;  5AXQ A;  2O8H A;  3UUO A;  1PTW A;  4HF4 A;  3ECN A;  3WD9 A;  1XN0 A;  3V93 A;  4XY2 A;  2H40 A;  3G4I A;  3HQZ A;  4LLX A;  4FCB A;  3HC8 A;  3O57 A;  3SL6 A;  1XM6 A;  2OUU A;  1Z1L A;  4LLP A;  1XOQ A;  5EDG B;  3B2R A;  3K4S A;  1XOM A;  3QPP A; 
#chains in the Genus database with same CATH homology
 3LXG A;  1XMY A;  1Y2H A;  4AJG A;  3G45 A;  3TGG A;  3SL3 A;  4OGB A;  3SNL A;  4MSE A;  1UHO A;  3O0J A;  5B25 A;  5B4L A;  1XOS A;  3DYL A;  3KKT A;  3QPO A;  3FRG A;  1XON A;  4LM1 A;  4G2L A;  4LLJ A;  3SHZ A;  3WI2 A;  4HTX A;  4NPW A;  4AEL A;  5K1I A;  1XM4 B;  1Q9M A;  4YS7 A;  4MD6 A;  3HDZ A;  4D08 A;  3HR1 A;  2OVY A;  3GWT A;  1XMU A;  3HQY A;  1ZKL A;  3WS9 A;  5C2H A;  4LM0 A;  4PM0 A;  4E90 A;  4HTZ A;  1RO9 A;  4OEX A;  3V94 A;  2OUR A;  2HD1 A;  5K9R A;  4JIB A;  2FM5 A;  4Y8C A;  3SL4 A;  3DYS A;  4TPP A;  1UDU A;  3WS8 A;  4MRZ A;  4Y86 A;  3G4K A;  4HEU A;  4WZI A;  2FM0 A;  5EDH A;  5K32 A;  1Y2B A;  3ITU A;  3D3P A;  4W1O A;  5C29 A;  3LY2 A;  4I15 A;  2OUN A;  1XMY B;  4PHL A;  1OYN A;  2QYN A;  1ZKN A;  3IAD A;  4MSA A;  4P1R A;  3K3H A;  3JSI A;  4LM2 A;  4AJD A;  4DDL A;  3O56 A;  4LKQ A;  1Y2E A;  3WYM A;  1TB7 A;  3ITM A;  4G2Y A;  5C2A A;  4ZO5 A;  3DY8 A;  1RKP A;  3G58 A;  3HMV A;  5B4K A;  3I8V A;  2H42 A;  2QYM A;  1XMU B;  3K3E A;  4BBX A;  1T9S A;  1ROR A;  4MS0 A;  4YQH A;  1SOJ A;  3WYL A;  5EDE A;  3SL8 A;  1UDT A;  2OUY A;  4DFF A;  4KP6 A;  4AJM A;  4PHW A;  5AXP A;  3SL5 A;  1F0J A;  4IA0 A;  3DYN A;  2OUQ A;  3SIE A;  3QI3 A;  5DH4 A;  3HQW A;  4MUW A;  4MSC A;  3QI4 A;  4X0F A;  3SNI A;  1TBB A;  2CHM A;  4WN1 A;  1SO2 A;  3JWR A;  4Y87 A;  4P0N A;  4AJF A;  4OEW A;  3TGE A;  5C1W A;  4NPV A;  2QYL A;  2OUV A;  1RO6 A;  4FCD A;  1Y2C A;  4WCU A;  3ECM A;  3SN7 A;  5C28 A;  1TB5 A;  4G2J A;  2OUS A;  1Y2D A;  4MVH A;  3JSW A;  3W5E A;  1MKD A;  4D09 A;  4G2W A;  4Y2B A;  3G3N A;  3V9B A;  4I9Z A;  2QYK A;  3UI7 A;  1XP0 A;  3G4L A;  1TBF A;  3DYQ A;  3JWQ A;  3QPN A;  1T9R A;  1TAZ A;  1XOZ A;  1Y2J A;  2WEY A;  4TPM A;  5EDG A;  2PW3 A;  4MSN A;  3BJC A;  5EDE B;  4C1I A;  4NW7 A;  1Y2K A;  5C2E A;  3TVX A;  4MRW A;  1XLZ A;  4GH6 A;  4MSH A;  1XOR A;  4LM3 A;  5EDI A;  5EDI B;  3SHY A;  4LLK A;  1XLX A;  3WYK A;  4QGE A;  3IAK A;  3N3Z A;  5I2R A;  2YY2 A;  1XM4 A;  1XOT A;  3G4G A;  2Y0J A;  2OUP A;  4MYQ A;  4LM4 A;  5DH5 A;  2H44 A;  2R8Q A;  2OVV A;  3IBJ A;  5AXQ A;  2O8H A;  3UUO A;  1PTW A;  4HF4 A;  3ECN A;  3WD9 A;  1XN0 A;  3V93 A;  4XY2 A;  2H40 A;  3G4I A;  3HQZ A;  4LLX A;  4FCB A;  3HC8 A;  3O57 A;  3SL6 A;  1XM6 A;  2OUU A;  1Z1L A;  4LLP A;  1XOQ A;  5EDG B;  3B2R A;  3K4S A;  1XOM A;  3QPP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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