1XP0A

Catalytic domain of human phosphodiesterase 5a in complex with vardenafil
Total Genus 135
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
326
structure length
326
Chain Sequence
EEETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHPGVSNQFLINTNSELALMYNDESVLEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords cGMP-specific 3',5'-cyclic phosphodiesterase
total genus 135
structure length 326
sequence length 326
ec nomenclature ec 3.1.4.35: 3',5'-cyclic-GMP phosphodiesterase.
pdb deposition date 2004-10-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00233 PDEase_I 3'5'-cyclic nucleotide phosphodiesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1300.10 Mainly Alpha Orthogonal Bundle Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain 1xp0A00
3HQWA 3G45A 1RO6A 4LM0A 1XM4B 2OURA 4AJDA 1XP0A 4MSCA 2OUVA 4HF4A 4LLKA 4MSAA 4HTZA 3G4IA 5EDEA 4D09A 1T9RA 4MSEA 3SNIA 3WYMA 3DYQA 2WEYA 1XMUA 3B2RA 1XORA 4P0NA 1MKDA 4MRWA 3GWTA 5DH5A 3V9BA 3WD9A 1Y2DA 3O0JA 1Y2HA 2PW3A 2OUYA 4NW7A 4MSHA 4OEXA 4IA0A 4PHLA 1RO9A 5EDGB 1ZKNA 1Y2KA 2QYKA 4LKQA 5EDEB 5AXQA 4JIBA 4LM1A 3G4LA 4AELA 1TB7A 4I15A 3QPPA 4MVHA 2FM5A 1PTWA 4GH6A 4OEWA 3SNLA 4G2JA 4MRZA 3ECMA 3G4GA 3ITUA 4AJMA 5K32A 3UI7A 1ZKLA 5K9RA 4E90A 3QPOA 3TVXA 1XLZA 3DY8A 3W5EA 3TGEA 4X0FA 4LM4A 1SOJA 4FCBA 4MUWA 5EDIB 3O57A 3JSIA 4D08A 1Y2BA 1TBFA 3HC8A 4NPWA 5B4LA 3SIEA 2QYMA 2H40A 3SHYA 4LLJA 2YY2A 1RORA 1Z1LA 3LY2A 4DDLA 2R8QA 4AJFA 1XMYA 3SHZA 3JWRA 4DFFA 3O56A 4XY2A 1UDTA 4G2WA 1XMUB 4ZO5A 4WCUA 5K1IA 5AXPA 1SO2A 3QI3A 1XONA 3G4KA 2OVYA 1XMYB 3SL6A 3JWQA 4PHWA 4WN1A 4P1RA 4KP6A 5B25A 2QYLA 1TAZA 1XOZA 4MSNA 4MS0A 5EDHA 1Q9MA 2QYNA 3HDZA 5DH4A 3DYLA 3SN7A 5C28A 3K3HA 1UDUA 3KKTA 4TPMA 5B4KA 2O8HA 1Y2CA 3UUOA 1T9SA 3K4SA 4W1OA 2HD1A 3DYNA 3V94A 1Y2JA 3SL4A 4LLXA 4MYQA 4PM0A 4AJGA 4YQHA 2H42A 3ECNA 3G3NA 5C2EA 1XM4A 1TB5A 5C2HA 3WS8A 1XOQA 1XOSA 4Y8CA 3HR1A 2OUNA 4FCDA 1XOMA 1F0JA 3JSWA 2Y0JA 4BBXA 3DYSA 1RKPA 3QI4A 4OGBA 4G2LA 2FM0A 3SL8A 1XOTA 1UHOA 3I8VA 4C1IA 4Y2BA 4Y86A 4HEUA 4G2YA 3IBJA 1XN0A 3LXGA 3WI2A 4Y87A 5EDGA 5C1WA 3IAKA 2OUQA 1OYNA 3WYLA 5C2AA 3D3PA 3V93A 3SL5A 2OVVA 1XM6A 4YS7A 5C29A 1TBBA 3ITMA 3BJCA 1Y2EA 3HMVA 4MD6A 3IADA 4LM3A 4TPPA 4LM2A 4WZIA 3SL3A 3FRGA 3K3EA 2CHMA 3TGGA 2OUUA 4I9ZA 4NPVA 1XLXA 3N3ZA 4QGEA 2OUPA 4LLPA 2H44A 2OUSA 3WS9A 3QPNA 3G58A 3WYKA 4HTXA 3HQZA 3HQYA 5I2RA 5EDIA
chains in the Genus database with same CATH superfamily
3HQWA 3G45A 1RO6A 4LM0A 1XM4B 2OURA 4AJDA 1XP0A 4MSCA 2OUVA 4HF4A 4LLKA 4MSAA 4HTZA 3G4IA 5EDEA 4D09A 1T9RA 4MSEA 3SNIA 3WYMA 3DYQA 2WEYA 1XMUA 3B2RA 1XORA 4P0NA 1MKDA 4MRWA 3GWTA 5DH5A 3V9BA 3WD9A 1Y2DA 3O0JA 1Y2HA 2PW3A 2OUYA 4NW7A 4MSHA 4OEXA 4IA0A 4PHLA 1RO9A 5EDGB 1ZKNA 1Y2KA 2QYKA 4LKQA 5EDEB 5AXQA 4JIBA 4LM1A 3G4LA 4AELA 1TB7A 4I15A 3QPPA 4MVHA 2FM5A 1PTWA 4GH6A 4OEWA 3SNLA 4G2JA 4MRZA 3ECMA 3G4GA 3ITUA 4AJMA 5K32A 3UI7A 1ZKLA 5K9RA 4E90A 3QPOA 3TVXA 1XLZA 3DY8A 3W5EA 3TGEA 4X0FA 4LM4A 1SOJA 4FCBA 4MUWA 5EDIB 3O57A 3JSIA 4D08A 1Y2BA 1TBFA 3HC8A 4NPWA 5B4LA 3SIEA 2QYMA 2H40A 3SHYA 4LLJA 2YY2A 1RORA 1Z1LA 3LY2A 4DDLA 2R8QA 4AJFA 1XMYA 3SHZA 3JWRA 4DFFA 3O56A 4XY2A 1UDTA 4G2WA 1XMUB 4ZO5A 4WCUA 5K1IA 5AXPA 1SO2A 3QI3A 1XONA 3G4KA 2OVYA 1XMYB 3SL6A 3JWQA 4PHWA 4WN1A 4P1RA 4KP6A 5B25A 2QYLA 1TAZA 1XOZA 4MSNA 4MS0A 5EDHA 1Q9MA 2QYNA 3HDZA 5DH4A 3DYLA 3SN7A 5C28A 3K3HA 1UDUA 3KKTA 4TPMA 5B4KA 2O8HA 1Y2CA 3UUOA 1T9SA 3K4SA 4W1OA 2HD1A 3DYNA 3V94A 1Y2JA 3SL4A 4LLXA 4MYQA 4PM0A 4AJGA 4YQHA 2H42A 3ECNA 3G3NA 5C2EA 1XM4A 1TB5A 5C2HA 3WS8A 1XOQA 1XOSA 4Y8CA 3HR1A 2OUNA 4FCDA 1XOMA 1F0JA 3JSWA 2Y0JA 4BBXA 3DYSA 1RKPA 3QI4A 4OGBA 4G2LA 2FM0A 3SL8A 1XOTA 1UHOA 3I8VA 4C1IA 4Y2BA 4Y86A 4HEUA 4G2YA 3IBJA 1XN0A 3LXGA 3WI2A 4Y87A 5EDGA 5C1WA 3IAKA 2OUQA 1OYNA 3WYLA 5C2AA 3D3PA 3V93A 3SL5A 2OVVA 1XM6A 4YS7A 5C29A 1TBBA 3ITMA 3BJCA 1Y2EA 3HMVA 4MD6A 3IADA 4LM3A 4TPPA 4LM2A 4WZIA 3SL3A 3FRGA 3K3EA 2CHMA 3TGGA 2OUUA 4I9ZA 4NPVA 1XLXA 3N3ZA 4QGEA 2OUPA 4LLPA 2H44A 2OUSA 3WS9A 3QPNA 3G58A 3WYKA 4HTXA 3HQZA 3HQYA 5I2RA 5EDIA
chains in the Genus database with same CATH topology
3HQWA 3G45A 1RO6A 4LM0A 1XM4B 2OURA 4AJDA 1XP0A 4MSCA 2OUVA 4HF4A 4LLKA 4MSAA 4HTZA 3G4IA 5EDEA 4D09A 1T9RA 4MSEA 3SNIA 3WYMA 3DYQA 2WEYA 1XMUA 3B2RA 1XORA 4P0NA 1MKDA 4MRWA 3GWTA 5DH5A 3V9BA 3WD9A 1Y2DA 3O0JA 1Y2HA 2PW3A 2OUYA 4NW7A 4MSHA 4OEXA 4IA0A 4PHLA 1RO9A 5EDGB 1ZKNA 1Y2KA 2QYKA 4LKQA 5EDEB 5AXQA 4JIBA 4LM1A 3G4LA 4AELA 1TB7A 4I15A 3QPPA 4MVHA 2FM5A 1PTWA 4GH6A 4OEWA 3SNLA 4G2JA 4MRZA 3ECMA 3G4GA 3ITUA 4AJMA 5K32A 3UI7A 1ZKLA 5K9RA 4E90A 3QPOA 3TVXA 1XLZA 3DY8A 3W5EA 3TGEA 4X0FA 4LM4A 1SOJA 4FCBA 4MUWA 5EDIB 3O57A 3JSIA 4D08A 1Y2BA 1TBFA 3HC8A 4NPWA 5B4LA 3SIEA 2QYMA 2H40A 3SHYA 4LLJA 2YY2A 1RORA 1Z1LA 3LY2A 4DDLA 2R8QA 4AJFA 1XMYA 3SHZA 3JWRA 4DFFA 3O56A 4XY2A 1UDTA 4G2WA 1XMUB 4ZO5A 4WCUA 5K1IA 5AXPA 1SO2A 3QI3A 1XONA 3G4KA 2OVYA 1XMYB 3SL6A 3JWQA 4PHWA 4WN1A 4P1RA 4KP6A 5B25A 2QYLA 1TAZA 1XOZA 4MSNA 4MS0A 5EDHA 1Q9MA 2QYNA 3HDZA 5DH4A 3DYLA 3SN7A 5C28A 3K3HA 1UDUA 3KKTA 4TPMA 5B4KA 2O8HA 1Y2CA 3UUOA 1T9SA 3K4SA 4W1OA 2HD1A 3DYNA 3V94A 1Y2JA 3SL4A 4LLXA 4MYQA 4PM0A 4AJGA 4YQHA 2H42A 3ECNA 3G3NA 5C2EA 1XM4A 1TB5A 5C2HA 3WS8A 1XOQA 1XOSA 4Y8CA 3HR1A 2OUNA 4FCDA 1XOMA 1F0JA 3JSWA 2Y0JA 4BBXA 3DYSA 1RKPA 3QI4A 4OGBA 4G2LA 2FM0A 3SL8A 1XOTA 1UHOA 3I8VA 4C1IA 4Y2BA 4Y86A 4HEUA 4G2YA 3IBJA 1XN0A 3LXGA 3WI2A 4Y87A 5EDGA 5C1WA 3IAKA 2OUQA 1OYNA 3WYLA 5C2AA 3D3PA 3V93A 3SL5A 2OVVA 1XM6A 4YS7A 5C29A 1TBBA 3ITMA 3BJCA 1Y2EA 3HMVA 4MD6A 3IADA 4LM3A 4TPPA 4LM2A 4WZIA 3SL3A 3FRGA 3K3EA 2CHMA 3TGGA 2OUUA 4I9ZA 4NPVA 1XLXA 3N3ZA 4QGEA 2OUPA 4LLPA 2H44A 2OUSA 3WS9A 3QPNA 3G58A 3WYKA 4HTXA 3HQZA 3HQYA 5I2RA 5EDIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HQW A;  3G45 A;  1RO6 A;  4LM0 A;  1XM4 B;  2OUR A;  4AJD A;  1XP0 A;  4MSC A;  2OUV A;  4HF4 A;  4LLK A;  4MSA A;  4HTZ A;  3G4I A;  5EDE A;  4D09 A;  1T9R A;  4MSE A;  3SNI A;  3WYM A;  3DYQ A;  2WEY A;  1XMU A;  3B2R A;  1XOR A;  4P0N A;  1MKD A;  4MRW A;  3GWT A;  5DH5 A;  3V9B A;  3WD9 A;  1Y2D A;  3O0J A;  1Y2H A;  2PW3 A;  2OUY A;  4NW7 A;  4MSH A;  4OEX A;  4IA0 A;  4PHL A;  1RO9 A;  5EDG B;  1ZKN A;  1Y2K A;  2QYK A;  4LKQ A;  5EDE B;  5AXQ A;  4JIB A;  4LM1 A;  3G4L A;  4AEL A;  1TB7 A;  4I15 A;  3QPP A;  4MVH A;  2FM5 A;  1PTW A;  4GH6 A;  4OEW A;  3SNL A;  4G2J A;  4MRZ A;  3ECM A;  3G4G A;  3ITU A;  4AJM A;  5K32 A;  3UI7 A;  1ZKL A;  5K9R A;  4E90 A;  3QPO A;  3TVX A;  1XLZ A;  3DY8 A;  3W5E A;  3TGE A;  4X0F A;  4LM4 A;  1SOJ A;  4FCB A;  4MUW A;  5EDI B;  3O57 A;  3JSI A;  4D08 A;  1Y2B A;  1TBF A;  3HC8 A;  4NPW A;  5B4L A;  3SIE A;  2QYM A;  2H40 A;  3SHY A;  4LLJ A;  2YY2 A;  1ROR A;  1Z1L A;  3LY2 A;  4DDL A;  2R8Q A;  4AJF A;  1XMY A;  3SHZ A;  3JWR A;  4DFF A;  3O56 A;  4XY2 A;  1UDT A;  4G2W A;  1XMU B;  4ZO5 A;  4WCU A;  5K1I A;  5AXP A;  1SO2 A;  3QI3 A;  1XON A;  3G4K A;  2OVY A;  1XMY B;  3SL6 A;  3JWQ A;  4PHW A;  4WN1 A;  4P1R A;  4KP6 A;  5B25 A;  2QYL A;  1TAZ A;  1XOZ A;  4MSN A;  4MS0 A;  5EDH A;  1Q9M A;  2QYN A;  3HDZ A;  5DH4 A;  3DYL A;  3SN7 A;  5C28 A;  3K3H A;  1UDU A;  3KKT A;  4TPM A;  5B4K A;  2O8H A;  1Y2C A;  3UUO A;  1T9S A;  3K4S A;  4W1O A;  2HD1 A;  3DYN A;  3V94 A;  1Y2J A;  3SL4 A;  4LLX A;  4MYQ A;  4PM0 A;  4AJG A;  4YQH A;  2H42 A;  3ECN A;  3G3N A;  5C2E A;  1XM4 A;  1TB5 A;  5C2H A;  3WS8 A;  1XOQ A;  1XOS A;  4Y8C A;  3HR1 A;  2OUN A;  4FCD A;  1XOM A;  1F0J A;  3JSW A;  2Y0J A;  4BBX A;  3DYS A;  1RKP A;  3QI4 A;  4OGB A;  4G2L A;  2FM0 A;  3SL8 A;  1XOT A;  1UHO A;  3I8V A;  4C1I A;  4Y2B A;  4Y86 A;  4HEU A;  4G2Y A;  3IBJ A;  1XN0 A;  3LXG A;  3WI2 A;  4Y87 A;  5EDG A;  5C1W A;  3IAK A;  2OUQ A;  1OYN A;  3WYL A;  5C2A A;  3D3P A;  3V93 A;  3SL5 A;  2OVV A;  1XM6 A;  4YS7 A;  5C29 A;  1TBB A;  3ITM A;  3BJC A;  1Y2E A;  3HMV A;  4MD6 A;  3IAD A;  4LM3 A;  4TPP A;  4LM2 A;  4WZI A;  3SL3 A;  3FRG A;  3K3E A;  2CHM A;  3TGG A;  2OUU A;  4I9Z A;  4NPV A;  1XLX A;  3N3Z A;  4QGE A;  2OUP A;  4LLP A;  2H44 A;  2OUS A;  3WS9 A;  3QPN A;  3G58 A;  3WYK A;  4HTX A;  3HQZ A;  3HQY A;  5I2R A;  5EDI A; 
#chains in the Genus database with same CATH topology
 3HQW A;  3G45 A;  1RO6 A;  4LM0 A;  1XM4 B;  2OUR A;  4AJD A;  1XP0 A;  4MSC A;  2OUV A;  4HF4 A;  4LLK A;  4MSA A;  4HTZ A;  3G4I A;  5EDE A;  4D09 A;  1T9R A;  4MSE A;  3SNI A;  3WYM A;  3DYQ A;  2WEY A;  1XMU A;  3B2R A;  1XOR A;  4P0N A;  1MKD A;  4MRW A;  3GWT A;  5DH5 A;  3V9B A;  3WD9 A;  1Y2D A;  3O0J A;  1Y2H A;  2PW3 A;  2OUY A;  4NW7 A;  4MSH A;  4OEX A;  4IA0 A;  4PHL A;  1RO9 A;  5EDG B;  1ZKN A;  1Y2K A;  2QYK A;  4LKQ A;  5EDE B;  5AXQ A;  4JIB A;  4LM1 A;  3G4L A;  4AEL A;  1TB7 A;  4I15 A;  3QPP A;  4MVH A;  2FM5 A;  1PTW A;  4GH6 A;  4OEW A;  3SNL A;  4G2J A;  4MRZ A;  3ECM A;  3G4G A;  3ITU A;  4AJM A;  5K32 A;  3UI7 A;  1ZKL A;  5K9R A;  4E90 A;  3QPO A;  3TVX A;  1XLZ A;  3DY8 A;  3W5E A;  3TGE A;  4X0F A;  4LM4 A;  1SOJ A;  4FCB A;  4MUW A;  5EDI B;  3O57 A;  3JSI A;  4D08 A;  1Y2B A;  1TBF A;  3HC8 A;  4NPW A;  5B4L A;  3SIE A;  2QYM A;  2H40 A;  3SHY A;  4LLJ A;  2YY2 A;  1ROR A;  1Z1L A;  3LY2 A;  4DDL A;  2R8Q A;  4AJF A;  1XMY A;  3SHZ A;  3JWR A;  4DFF A;  3O56 A;  4XY2 A;  1UDT A;  4G2W A;  1XMU B;  4ZO5 A;  4WCU A;  5K1I A;  5AXP A;  1SO2 A;  3QI3 A;  1XON A;  3G4K A;  2OVY A;  1XMY B;  3SL6 A;  3JWQ A;  4PHW A;  4WN1 A;  4P1R A;  4KP6 A;  5B25 A;  2QYL A;  1TAZ A;  1XOZ A;  4MSN A;  4MS0 A;  5EDH A;  1Q9M A;  2QYN A;  3HDZ A;  5DH4 A;  3DYL A;  3SN7 A;  5C28 A;  3K3H A;  1UDU A;  3KKT A;  4TPM A;  5B4K A;  2O8H A;  1Y2C A;  3UUO A;  1T9S A;  3K4S A;  4W1O A;  2HD1 A;  3DYN A;  3V94 A;  1Y2J A;  3SL4 A;  4LLX A;  4MYQ A;  4PM0 A;  4AJG A;  4YQH A;  2H42 A;  3ECN A;  3G3N A;  5C2E A;  1XM4 A;  1TB5 A;  5C2H A;  3WS8 A;  1XOQ A;  1XOS A;  4Y8C A;  3HR1 A;  2OUN A;  4FCD A;  1XOM A;  1F0J A;  3JSW A;  2Y0J A;  4BBX A;  3DYS A;  1RKP A;  3QI4 A;  4OGB A;  4G2L A;  2FM0 A;  3SL8 A;  1XOT A;  1UHO A;  3I8V A;  4C1I A;  4Y2B A;  4Y86 A;  4HEU A;  4G2Y A;  3IBJ A;  1XN0 A;  3LXG A;  3WI2 A;  4Y87 A;  5EDG A;  5C1W A;  3IAK A;  2OUQ A;  1OYN A;  3WYL A;  5C2A A;  3D3P A;  3V93 A;  3SL5 A;  2OVV A;  1XM6 A;  4YS7 A;  5C29 A;  1TBB A;  3ITM A;  3BJC A;  1Y2E A;  3HMV A;  4MD6 A;  3IAD A;  4LM3 A;  4TPP A;  4LM2 A;  4WZI A;  3SL3 A;  3FRG A;  3K3E A;  2CHM A;  3TGG A;  2OUU A;  4I9Z A;  4NPV A;  1XLX A;  3N3Z A;  4QGE A;  2OUP A;  4LLP A;  2H44 A;  2OUS A;  3WS9 A;  3QPN A;  3G58 A;  3WYK A;  4HTX A;  3HQZ A;  3HQY A;  5I2R A;  5EDI A; 
#chains in the Genus database with same CATH homology
 3HQW A;  3G45 A;  1RO6 A;  4LM0 A;  1XM4 B;  2OUR A;  4AJD A;  1XP0 A;  4MSC A;  2OUV A;  4HF4 A;  4LLK A;  4MSA A;  4HTZ A;  3G4I A;  5EDE A;  4D09 A;  1T9R A;  4MSE A;  3SNI A;  3WYM A;  3DYQ A;  2WEY A;  1XMU A;  3B2R A;  1XOR A;  4P0N A;  1MKD A;  4MRW A;  3GWT A;  5DH5 A;  3V9B A;  3WD9 A;  1Y2D A;  3O0J A;  1Y2H A;  2PW3 A;  2OUY A;  4NW7 A;  4MSH A;  4OEX A;  4IA0 A;  4PHL A;  1RO9 A;  5EDG B;  1ZKN A;  1Y2K A;  2QYK A;  4LKQ A;  5EDE B;  5AXQ A;  4JIB A;  4LM1 A;  3G4L A;  4AEL A;  1TB7 A;  4I15 A;  3QPP A;  4MVH A;  2FM5 A;  1PTW A;  4GH6 A;  4OEW A;  3SNL A;  4G2J A;  4MRZ A;  3ECM A;  3G4G A;  3ITU A;  4AJM A;  5K32 A;  3UI7 A;  1ZKL A;  5K9R A;  4E90 A;  3QPO A;  3TVX A;  1XLZ A;  3DY8 A;  3W5E A;  3TGE A;  4X0F A;  4LM4 A;  1SOJ A;  4FCB A;  4MUW A;  5EDI B;  3O57 A;  3JSI A;  4D08 A;  1Y2B A;  1TBF A;  3HC8 A;  4NPW A;  5B4L A;  3SIE A;  2QYM A;  2H40 A;  3SHY A;  4LLJ A;  2YY2 A;  1ROR A;  1Z1L A;  3LY2 A;  4DDL A;  2R8Q A;  4AJF A;  1XMY A;  3SHZ A;  3JWR A;  4DFF A;  3O56 A;  4XY2 A;  1UDT A;  4G2W A;  1XMU B;  4ZO5 A;  4WCU A;  5K1I A;  5AXP A;  1SO2 A;  3QI3 A;  1XON A;  3G4K A;  2OVY A;  1XMY B;  3SL6 A;  3JWQ A;  4PHW A;  4WN1 A;  4P1R A;  4KP6 A;  5B25 A;  2QYL A;  1TAZ A;  1XOZ A;  4MSN A;  4MS0 A;  5EDH A;  1Q9M A;  2QYN A;  3HDZ A;  5DH4 A;  3DYL A;  3SN7 A;  5C28 A;  3K3H A;  1UDU A;  3KKT A;  4TPM A;  5B4K A;  2O8H A;  1Y2C A;  3UUO A;  1T9S A;  3K4S A;  4W1O A;  2HD1 A;  3DYN A;  3V94 A;  1Y2J A;  3SL4 A;  4LLX A;  4MYQ A;  4PM0 A;  4AJG A;  4YQH A;  2H42 A;  3ECN A;  3G3N A;  5C2E A;  1XM4 A;  1TB5 A;  5C2H A;  3WS8 A;  1XOQ A;  1XOS A;  4Y8C A;  3HR1 A;  2OUN A;  4FCD A;  1XOM A;  1F0J A;  3JSW A;  2Y0J A;  4BBX A;  3DYS A;  1RKP A;  3QI4 A;  4OGB A;  4G2L A;  2FM0 A;  3SL8 A;  1XOT A;  1UHO A;  3I8V A;  4C1I A;  4Y2B A;  4Y86 A;  4HEU A;  4G2Y A;  3IBJ A;  1XN0 A;  3LXG A;  3WI2 A;  4Y87 A;  5EDG A;  5C1W A;  3IAK A;  2OUQ A;  1OYN A;  3WYL A;  5C2A A;  3D3P A;  3V93 A;  3SL5 A;  2OVV A;  1XM6 A;  4YS7 A;  5C29 A;  1TBB A;  3ITM A;  3BJC A;  1Y2E A;  3HMV A;  4MD6 A;  3IAD A;  4LM3 A;  4TPP A;  4LM2 A;  4WZI A;  3SL3 A;  3FRG A;  3K3E A;  2CHM A;  3TGG A;  2OUU A;  4I9Z A;  4NPV A;  1XLX A;  3N3Z A;  4QGE A;  2OUP A;  4LLP A;  2H44 A;  2OUS A;  3WS9 A;  3QPN A;  3G58 A;  3WYK A;  4HTX A;  3HQZ A;  3HQY A;  5I2R A;  5EDI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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