1XS1A

Dctp deaminase from escherichia coli in complex with dutp
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
193
structure length
193
Chain Sequence
MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLDEGEAFYLHPGELALAVTLESVTLPADLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAVRPYNRREDAKYRNQQGAVASRIDKD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Deoxycytidine triphosphate deaminase
total genus 46
structure length 193
sequence length 193
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.5.4.13: dCTP deaminase.
pdb deposition date 2004-10-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 1xs1A00
3SO2A 3ZF2A 2D4MA 3HHQA 2OL1A 2WE3A 4DHKA 1DUCA 4A6AA 2WE1A 2OKEA 4AOOA 1VYQA 3TSLA 2BT1A 1F7DA 2BSYA 2HXDA 2J4HA 4APZ1 3ZF3A 1MQ7A 2XY3A 2ZDCA 1OGHA 3ZF6A 3HZAA 1F7KA 2WE2A 3TP1A 3TQZA 3CA9A 2XCEA 2OKDA 1SEHA 3EHWA 1F7QA 1DUDA 1RNJA 3F4FA 4WRKA 1SLHA 3I93A 3T60A 1F7RA 1F7NA 2Y8CA 3ARAA 2HXBA 2QXXA 2OKBA 1SMCA 1EUWA 3LQWA 1PKKA 4GK6A 2HRMA 3TPWA 1XS6A 4XJCA 2BAZA 1PKJA 3TRLA 3T70A 1Q5UX 2HQUA 1SIXA 3LOJA 3ARNA 1SM8A 2R9QA 3TQ3A 2PC5A 1Q5HA 3TTAA 1DUPA 2OL0A 3TS6A 1F7OA 4GV8A 3ZF1A 2D4NA 3C3IA 3P48A 4OOQA 3ZEZA 5CCOA 2V9XA 5EDDA 3ZF4A 3TQ4A 4LHRA 1RN8A 2Y1TA 3T64A 4OOPA 2J4QA 1XS1A 3MBQA 2XX6A 1PKHA 2XCDA 1EU5A 3TPNA 1F7PA 4AOZA 3ZF0A 3GF0A 3T6YA 3ECYA 1SNFA 3TRNA 1DUTA 3KM3A 2WE0A 3ZF5A 2QLPA 2HR6A 5F9KA 4GCYA 2D4LA 5CCTA 5ECTA 1SYLA 2PY4A 2YZJA 3H6XA 3TPSA 3C2TA 3TPYA 4B0HA 3H6DA 3MDXA 3TQ5A 1SJNA 4AO5A 1DUNA 1XS4A
chains in the Genus database with same CATH superfamily
3SO2A 3ZF2A 2D4MA 3HHQA 2OL1A 2WE3A 4DHKA 1DUCA 4A6AA 2WE1A 2OKEA 4AOOA 1VYQA 3TSLA 2BT1A 1F7DA 2BSYA 2HXDA 2J4HA 4APZ1 3ZF3A 1MQ7A 2XY3A 2ZDCA 1OGHA 3ZF6A 3HZAA 1F7KA 2WE2A 3TP1A 3TQZA 3CA9A 2XCEA 2OKDA 1TULA 1SEHA 3EHWA 1F7QA 1DUDA 1RNJA 3F4FA 4WRKA 1SLHA 3I93A 3T60A 1F7RA 1F7NA 2Y8CA 3ARAA 2HXBA 2QXXA 2OKBA 1SMCA 1EUWA 3LQWA 1PKKA 4GK6A 2HRMA 3TPWA 1XS6A 4XJCA 2BAZA 1PKJA 3TRLA 3T70A 1Q5UX 2HQUA 1SIXA 3LOJA 3ARNA 1SM8A 2R9QA 3TQ3A 2PC5A 1Q5HA 3TTAA 1DUPA 2OL0A 3TS6A 1F7OA 4GV8A 3ZF1A 2D4NA 3C3IA 3P48A 4OOQA 3ZEZA 5CCOA 2V9XA 5EDDA 3ZF4A 3TQ4A 4LHRA 1RN8A 2Y1TA 3T64A 4OOPA 2J4QA 1XS1A 3MBQA 2XX6A 1PKHA 2XCDA 1EU5A 3TPNA 1F7PA 4AOZA 3ZF0A 3GF0A 3T6YA 3ECYA 1SNFA 3TRNA 1DUTA 3KM3A 2WE0A 3ZF5A 2QLPA 2HR6A 5F9KA 4GCYA 2D4LA 5CCTA 5ECTA 1SYLA 2PY4A 2YZJA 3H6XA 3TPSA 3C2TA 3TPYA 4B0HA 3H6DA 3MDXA 3TQ5A 1SJNA 4AO5A 1DUNA 1XS4A
chains in the Genus database with same CATH topology
3SO2A 3ZF2A 2D4MA 3HHQA 2OL1A 2WE3A 4DHKA 1DUCA 4A6AA 2WE1A 2OKEA 4AOOA 1VYQA 3TSLA 2BT1A 1F7DA 2BSYA 2HXDA 2J4HA 4APZ1 3ZF3A 1MQ7A 2XY3A 2ZDCA 1OGHA 3ZF6A 3HZAA 1F7KA 2WE2A 3TP1A 3TQZA 3CA9A 2XCEA 2OKDA 1SEHA 3EHWA 1F7QA 1DUDA 1RNJA 3F4FA 4WRKA 1SLHA 3I93A 3T60A 1F7RA 1F7NA 2Y8CA 3ARAA 2HXBA 2QXXA 2OKBA 1SMCA 1EUWA 3LQWA 1PKKA 4GK6A 2HRMA 3TPWA 1XS6A 4XJCA 2BAZA 1PKJA 3TRLA 3T70A 1Q5UX 2HQUA 1SIXA 3LOJA 3ARNA 1SM8A 2R9QA 3TQ3A 2PC5A 1Q5HA 3TTAA 1DUPA 2OL0A 3TS6A 1F7OA 4GV8A 3ZF1A 2D4NA 3C3IA 3P48A 4OOQA 3ZEZA 5CCOA 2V9XA 5EDDA 3ZF4A 3TQ4A 4LHRA 1RN8A 2Y1TA 3T64A 4OOPA 2J4QA 1XS1A 3MBQA 2XX6A 1PKHA 2XCDA 1EU5A 3TPNA 1F7PA 4AOZA 3ZF0A 3GF0A 3T6YA 3ECYA 1SNFA 3TRNA 1DUTA 3KM3A 2WE0A 3ZF5A 2QLPA 2HR6A 5F9KA 4GCYA 2D4LA 5CCTA 5ECTA 1SYLA 2PY4A 2YZJA 3H6XA 3TPSA 3C2TA 3TPYA 4B0HA 3H6DA 3MDXA 3TQ5A 1SJNA 4AO5A 1DUNA 1XS4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SO2 A;  3ZF2 A;  2D4M A;  3HHQ A;  2OL1 A;  2WE3 A;  4DHK A;  1DUC A;  4A6A A;  2WE1 A;  2OKE A;  4AOO A;  1VYQ A;  3TSL A;  2BT1 A;  1F7D A;  2BSY A;  2HXD A;  2J4H A;  4APZ 1;  3ZF3 A;  1MQ7 A;  2XY3 A;  2ZDC A;  1OGH A;  3ZF6 A;  3HZA A;  1F7K A;  2WE2 A;  3TP1 A;  3TQZ A;  3CA9 A;  2XCE A;  2OKD A;  1SEH A;  3EHW A;  1F7Q A;  1DUD A;  1RNJ A;  3F4F A;  4WRK A;  1SLH A;  3I93 A;  3T60 A;  1F7R A;  1F7N A;  2Y8C A;  3ARA A;  2HXB A;  2QXX A;  2OKB A;  1SMC A;  1EUW A;  3LQW A;  1PKK A;  4GK6 A;  2HRM A;  3TPW A;  1XS6 A;  4XJC A;  2BAZ A;  1PKJ A;  3TRL A;  3T70 A;  1Q5U X;  2HQU A;  1SIX A;  3LOJ A;  3ARN A;  1SM8 A;  2R9Q A;  3TQ3 A;  2PC5 A;  1Q5H A;  3TTA A;  1DUP A;  2OL0 A;  3TS6 A;  1F7O A;  4GV8 A;  3ZF1 A;  2D4N A;  3C3I A;  3P48 A;  4OOQ A;  3ZEZ A;  5CCO A;  2V9X A;  5EDD A;  3ZF4 A;  3TQ4 A;  4LHR A;  1RN8 A;  2Y1T A;  3T64 A;  4OOP A;  2J4Q A;  1XS1 A;  3MBQ A;  2XX6 A;  1PKH A;  2XCD A;  1EU5 A;  3TPN A;  1F7P A;  4AOZ A;  3ZF0 A;  3GF0 A;  3T6Y A;  3ECY A;  1SNF A;  3TRN A;  1DUT A;  3KM3 A;  2WE0 A;  3ZF5 A;  2QLP A;  2HR6 A;  5F9K A;  4GCY A;  2D4L A;  5CCT A;  5ECT A;  1SYL A;  2PY4 A;  2YZJ A;  3H6X A;  3TPS A;  3C2T A;  3TPY A;  4B0H A;  3H6D A;  3MDX A;  3TQ5 A;  1SJN A;  4AO5 A;  1DUN A;  1XS4 A; 
#chains in the Genus database with same CATH topology
 3SO2 A;  3ZF2 A;  2D4M A;  3HHQ A;  2OL1 A;  2WE3 A;  4DHK A;  1DUC A;  4A6A A;  2WE1 A;  2OKE A;  4AOO A;  1VYQ A;  3TSL A;  2BT1 A;  1F7D A;  2BSY A;  2HXD A;  2J4H A;  4APZ 1;  3ZF3 A;  1MQ7 A;  2XY3 A;  2ZDC A;  1OGH A;  3ZF6 A;  3HZA A;  1F7K A;  2WE2 A;  3TP1 A;  3TQZ A;  3CA9 A;  2XCE A;  2OKD A;  1TUL A;  1SEH A;  3EHW A;  1F7Q A;  1DUD A;  1RNJ A;  3F4F A;  4WRK A;  1SLH A;  3I93 A;  3T60 A;  1F7R A;  1F7N A;  2Y8C A;  3ARA A;  2HXB A;  2QXX A;  2OKB A;  1SMC A;  1EUW A;  3LQW A;  1PKK A;  4GK6 A;  2HRM A;  3TPW A;  1XS6 A;  4XJC A;  2BAZ A;  1PKJ A;  3TRL A;  3T70 A;  1Q5U X;  2HQU A;  1SIX A;  3LOJ A;  3ARN A;  1SM8 A;  2R9Q A;  3TQ3 A;  2PC5 A;  1Q5H A;  3TTA A;  1DUP A;  2OL0 A;  3TS6 A;  1F7O A;  4GV8 A;  3ZF1 A;  2D4N A;  3C3I A;  3P48 A;  4OOQ A;  3ZEZ A;  5CCO A;  2V9X A;  5EDD A;  3ZF4 A;  3TQ4 A;  4LHR A;  1RN8 A;  2Y1T A;  3T64 A;  4OOP A;  2J4Q A;  1XS1 A;  3MBQ A;  2XX6 A;  1PKH A;  2XCD A;  1EU5 A;  3TPN A;  1F7P A;  4AOZ A;  3ZF0 A;  3GF0 A;  3T6Y A;  3ECY A;  1SNF A;  3TRN A;  1DUT A;  3KM3 A;  2WE0 A;  3ZF5 A;  2QLP A;  2HR6 A;  5F9K A;  4GCY A;  2D4L A;  5CCT A;  5ECT A;  1SYL A;  2PY4 A;  2YZJ A;  3H6X A;  3TPS A;  3C2T A;  3TPY A;  4B0H A;  3H6D A;  3MDX A;  3TQ5 A;  1SJN A;  4AO5 A;  1DUN A;  1XS4 A; 
#chains in the Genus database with same CATH homology
 3SO2 A;  3ZF2 A;  2D4M A;  3HHQ A;  2OL1 A;  2WE3 A;  4DHK A;  1DUC A;  4A6A A;  2WE1 A;  2OKE A;  4AOO A;  1VYQ A;  3TSL A;  2BT1 A;  1F7D A;  2BSY A;  2HXD A;  2J4H A;  4APZ 1;  3ZF3 A;  1MQ7 A;  2XY3 A;  2ZDC A;  1OGH A;  3ZF6 A;  3HZA A;  1F7K A;  2WE2 A;  3TP1 A;  3TQZ A;  3CA9 A;  2XCE A;  2OKD A;  1SEH A;  3EHW A;  1F7Q A;  1DUD A;  1RNJ A;  3F4F A;  4WRK A;  1SLH A;  3I93 A;  3T60 A;  1F7R A;  1F7N A;  2Y8C A;  3ARA A;  2HXB A;  2QXX A;  2OKB A;  1SMC A;  1EUW A;  3LQW A;  1PKK A;  4GK6 A;  2HRM A;  3TPW A;  1XS6 A;  4XJC A;  2BAZ A;  1PKJ A;  3TRL A;  3T70 A;  1Q5U X;  2HQU A;  1SIX A;  3LOJ A;  3ARN A;  1SM8 A;  2R9Q A;  3TQ3 A;  2PC5 A;  1Q5H A;  3TTA A;  1DUP A;  2OL0 A;  3TS6 A;  1F7O A;  4GV8 A;  3ZF1 A;  2D4N A;  3C3I A;  3P48 A;  4OOQ A;  3ZEZ A;  5CCO A;  2V9X A;  5EDD A;  3ZF4 A;  3TQ4 A;  4LHR A;  1RN8 A;  2Y1T A;  3T64 A;  4OOP A;  2J4Q A;  1XS1 A;  3MBQ A;  2XX6 A;  1PKH A;  2XCD A;  1EU5 A;  3TPN A;  1F7P A;  4AOZ A;  3ZF0 A;  3GF0 A;  3T6Y A;  3ECY A;  1SNF A;  3TRN A;  1DUT A;  3KM3 A;  2WE0 A;  3ZF5 A;  2QLP A;  2HR6 A;  5F9K A;  4GCY A;  2D4L A;  5CCT A;  5ECT A;  1SYL A;  2PY4 A;  2YZJ A;  3H6X A;  3TPS A;  3C2T A;  3TPY A;  4B0H A;  3H6D A;  3MDX A;  3TQ5 A;  1SJN A;  4AO5 A;  1DUN A;  1XS4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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