1XS4A

Dctp deaminase from escherichia coli- e138a mutant enzyme in complex with dctp
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
193
structure length
193
Chain Sequence
MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLDEGEAFYLHPGELALAVTLESVTLPADLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLAFYNSGKLPLALRPGMLIGALSFEPLSGPAVRPYNRREDAKYRNQQGAVASRIDKD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Deoxycytidine triphosphate deaminase
total genus 43
structure length 193
sequence length 193
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.5.4.13: dCTP deaminase.
pdb deposition date 2004-10-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 1xs4A00
3TPSA 2BSYA 3ZF6A 3LOJA 4LHRA 2Y8CA 3C2TA 3LQWA 2PY4A 3ZF4A 2XCDA 1DUNA 2J4HA 2D4NA 2R9QA 4B0HA 1F7QA 2V9XA 1F7RA 3C3IA 2XCEA 3H6DA 3GF0A 4DHKA 1SJNA 4OOQA 2HR6A 3TQ3A 3TQ4A 4A6AA 1XS1A 1RNJA 5F9KA 3TSLA 2QXXA 1MQ7A 3TQZA 1Q5UX 2YZJA 3P48A 1EU5A 4GCYA 4XJCA 3TPWA 2Y1TA 1RN8A 1PKJA 3ZF3A 1F7NA 3HZAA 3TPYA 1SM8A 3TS6A 1DUDA 3HHQA 4AO5A 1SYLA 1PKHA 1PKKA 4AOOA 3EHWA 1EUWA 2OL1A 2D4MA 4AOZA 3ECYA 1F7OA 1DUCA 5EDDA 3H6XA 1OGHA 1F7PA 5CCOA 3TRLA 2OKBA 2PC5A 1XS4A 1DUPA 1SEHA 1Q5HA 3F4FA 4OOPA 3TPNA 3ARNA 3I93A 2OKDA 1SLHA 1XS6A 3ARAA 3MBQA 5CCTA 4WRKA 3T6YA 2XY3A 2BAZA 1SNFA 2WE2A 2HRMA 3TRNA 1F7DA 2D4LA 3T60A 2QLPA 2WE3A 2BT1A 3KM3A 3ZF0A 3MDXA 3TQ5A 1SMCA 4GV8A 2WE1A 3ZEZA 2HXBA 1F7KA 1DUTA 3SO2A 2HXDA 1SIXA 3CA9A 3TTAA 3TP1A 2HQUA 3ZF5A 3ZF2A 2OKEA 2ZDCA 4GK6A 5ECTA 3ZF1A 2OL0A 1VYQA 3T64A 2J4QA 3T70A 2XX6A 4APZ1 2WE0A
chains in the Genus database with same CATH superfamily
3TPSA 2BSYA 3ZF6A 3LOJA 4LHRA 2Y8CA 3C2TA 3LQWA 2PY4A 3ZF4A 2XCDA 1DUNA 2J4HA 2D4NA 2R9QA 4B0HA 1F7QA 2V9XA 1F7RA 3C3IA 2XCEA 3H6DA 3GF0A 4DHKA 1SJNA 4OOQA 2HR6A 3TQ3A 3TQ4A 4A6AA 1XS1A 1RNJA 5F9KA 3TSLA 2QXXA 1MQ7A 3TQZA 1Q5UX 2YZJA 3P48A 1EU5A 4GCYA 4XJCA 3TPWA 2Y1TA 1RN8A 1PKJA 3ZF3A 1F7NA 3HZAA 3TPYA 1SM8A 3TS6A 1DUDA 3HHQA 4AO5A 1SYLA 1PKHA 1PKKA 4AOOA 3EHWA 1EUWA 2OL1A 2D4MA 4AOZA 3ECYA 1F7OA 1DUCA 5EDDA 3H6XA 1OGHA 1F7PA 5CCOA 3TRLA 2OKBA 2PC5A 1XS4A 1DUPA 1SEHA 1Q5HA 3F4FA 4OOPA 3TPNA 3ARNA 3I93A 2OKDA 1SLHA 1XS6A 3ARAA 3MBQA 1TULA 5CCTA 4WRKA 3T6YA 2XY3A 2BAZA 1SNFA 2WE2A 2HRMA 3TRNA 1F7DA 2D4LA 3T60A 2QLPA 2WE3A 2BT1A 3KM3A 3ZF0A 3MDXA 3TQ5A 1SMCA 4GV8A 2WE1A 3ZEZA 2HXBA 1F7KA 1DUTA 3SO2A 2HXDA 1SIXA 3CA9A 3TTAA 3TP1A 2HQUA 3ZF5A 3ZF2A 2OKEA 2ZDCA 4GK6A 5ECTA 3ZF1A 2OL0A 1VYQA 3T64A 2J4QA 3T70A 2XX6A 4APZ1 2WE0A
chains in the Genus database with same CATH topology
3TPSA 2BSYA 3ZF6A 3LOJA 4LHRA 2Y8CA 3C2TA 3LQWA 2PY4A 3ZF4A 2XCDA 1DUNA 2J4HA 2D4NA 2R9QA 4B0HA 1F7QA 2V9XA 1F7RA 3C3IA 2XCEA 3H6DA 3GF0A 4DHKA 1SJNA 4OOQA 2HR6A 3TQ3A 3TQ4A 4A6AA 1XS1A 1RNJA 5F9KA 3TSLA 2QXXA 1MQ7A 3TQZA 1Q5UX 2YZJA 3P48A 1EU5A 4GCYA 4XJCA 3TPWA 2Y1TA 1RN8A 1PKJA 3ZF3A 1F7NA 3HZAA 3TPYA 1SM8A 3TS6A 1DUDA 3HHQA 4AO5A 1SYLA 1PKHA 1PKKA 4AOOA 3EHWA 1EUWA 2OL1A 2D4MA 4AOZA 3ECYA 1F7OA 1DUCA 5EDDA 3H6XA 1OGHA 1F7PA 5CCOA 3TRLA 2OKBA 2PC5A 1XS4A 1DUPA 1SEHA 1Q5HA 3F4FA 4OOPA 3TPNA 3ARNA 3I93A 2OKDA 1SLHA 1XS6A 3ARAA 3MBQA 5CCTA 4WRKA 3T6YA 2XY3A 2BAZA 1SNFA 2WE2A 2HRMA 3TRNA 1F7DA 2D4LA 3T60A 2QLPA 2WE3A 2BT1A 3KM3A 3ZF0A 3MDXA 3TQ5A 1SMCA 4GV8A 2WE1A 3ZEZA 2HXBA 1F7KA 1DUTA 3SO2A 2HXDA 1SIXA 3CA9A 3TTAA 3TP1A 2HQUA 3ZF5A 3ZF2A 2OKEA 2ZDCA 4GK6A 5ECTA 3ZF1A 2OL0A 1VYQA 3T64A 2J4QA 3T70A 2XX6A 4APZ1 2WE0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TPS A;  2BSY A;  3ZF6 A;  3LOJ A;  4LHR A;  2Y8C A;  3C2T A;  3LQW A;  2PY4 A;  3ZF4 A;  2XCD A;  1DUN A;  2J4H A;  2D4N A;  2R9Q A;  4B0H A;  1F7Q A;  2V9X A;  1F7R A;  3C3I A;  2XCE A;  3H6D A;  3GF0 A;  4DHK A;  1SJN A;  4OOQ A;  2HR6 A;  3TQ3 A;  3TQ4 A;  4A6A A;  1XS1 A;  1RNJ A;  5F9K A;  3TSL A;  2QXX A;  1MQ7 A;  3TQZ A;  1Q5U X;  2YZJ A;  3P48 A;  1EU5 A;  4GCY A;  4XJC A;  3TPW A;  2Y1T A;  1RN8 A;  1PKJ A;  3ZF3 A;  1F7N A;  3HZA A;  3TPY A;  1SM8 A;  3TS6 A;  1DUD A;  3HHQ A;  4AO5 A;  1SYL A;  1PKH A;  1PKK A;  4AOO A;  3EHW A;  1EUW A;  2OL1 A;  2D4M A;  4AOZ A;  3ECY A;  1F7O A;  1DUC A;  5EDD A;  3H6X A;  1OGH A;  1F7P A;  5CCO A;  3TRL A;  2OKB A;  2PC5 A;  1XS4 A;  1DUP A;  1SEH A;  1Q5H A;  3F4F A;  4OOP A;  3TPN A;  3ARN A;  3I93 A;  2OKD A;  1SLH A;  1XS6 A;  3ARA A;  3MBQ A;  5CCT A;  4WRK A;  3T6Y A;  2XY3 A;  2BAZ A;  1SNF A;  2WE2 A;  2HRM A;  3TRN A;  1F7D A;  2D4L A;  3T60 A;  2QLP A;  2WE3 A;  2BT1 A;  3KM3 A;  3ZF0 A;  3MDX A;  3TQ5 A;  1SMC A;  4GV8 A;  2WE1 A;  3ZEZ A;  2HXB A;  1F7K A;  1DUT A;  3SO2 A;  2HXD A;  1SIX A;  3CA9 A;  3TTA A;  3TP1 A;  2HQU A;  3ZF5 A;  3ZF2 A;  2OKE A;  2ZDC A;  4GK6 A;  5ECT A;  3ZF1 A;  2OL0 A;  1VYQ A;  3T64 A;  2J4Q A;  3T70 A;  2XX6 A;  4APZ 1;  2WE0 A; 
#chains in the Genus database with same CATH topology
 3TPS A;  2BSY A;  3ZF6 A;  3LOJ A;  4LHR A;  2Y8C A;  3C2T A;  3LQW A;  2PY4 A;  3ZF4 A;  2XCD A;  1DUN A;  2J4H A;  2D4N A;  2R9Q A;  4B0H A;  1F7Q A;  2V9X A;  1F7R A;  3C3I A;  2XCE A;  3H6D A;  3GF0 A;  4DHK A;  1SJN A;  4OOQ A;  2HR6 A;  3TQ3 A;  3TQ4 A;  4A6A A;  1XS1 A;  1RNJ A;  5F9K A;  3TSL A;  2QXX A;  1MQ7 A;  3TQZ A;  1Q5U X;  2YZJ A;  3P48 A;  1EU5 A;  4GCY A;  4XJC A;  3TPW A;  2Y1T A;  1RN8 A;  1PKJ A;  3ZF3 A;  1F7N A;  3HZA A;  3TPY A;  1SM8 A;  3TS6 A;  1DUD A;  3HHQ A;  4AO5 A;  1SYL A;  1PKH A;  1PKK A;  4AOO A;  3EHW A;  1EUW A;  2OL1 A;  2D4M A;  4AOZ A;  3ECY A;  1F7O A;  1DUC A;  5EDD A;  3H6X A;  1OGH A;  1F7P A;  5CCO A;  3TRL A;  2OKB A;  2PC5 A;  1XS4 A;  1DUP A;  1SEH A;  1Q5H A;  3F4F A;  4OOP A;  3TPN A;  3ARN A;  3I93 A;  2OKD A;  1SLH A;  1XS6 A;  3ARA A;  3MBQ A;  1TUL A;  5CCT A;  4WRK A;  3T6Y A;  2XY3 A;  2BAZ A;  1SNF A;  2WE2 A;  2HRM A;  3TRN A;  1F7D A;  2D4L A;  3T60 A;  2QLP A;  2WE3 A;  2BT1 A;  3KM3 A;  3ZF0 A;  3MDX A;  3TQ5 A;  1SMC A;  4GV8 A;  2WE1 A;  3ZEZ A;  2HXB A;  1F7K A;  1DUT A;  3SO2 A;  2HXD A;  1SIX A;  3CA9 A;  3TTA A;  3TP1 A;  2HQU A;  3ZF5 A;  3ZF2 A;  2OKE A;  2ZDC A;  4GK6 A;  5ECT A;  3ZF1 A;  2OL0 A;  1VYQ A;  3T64 A;  2J4Q A;  3T70 A;  2XX6 A;  4APZ 1;  2WE0 A; 
#chains in the Genus database with same CATH homology
 3TPS A;  2BSY A;  3ZF6 A;  3LOJ A;  4LHR A;  2Y8C A;  3C2T A;  3LQW A;  2PY4 A;  3ZF4 A;  2XCD A;  1DUN A;  2J4H A;  2D4N A;  2R9Q A;  4B0H A;  1F7Q A;  2V9X A;  1F7R A;  3C3I A;  2XCE A;  3H6D A;  3GF0 A;  4DHK A;  1SJN A;  4OOQ A;  2HR6 A;  3TQ3 A;  3TQ4 A;  4A6A A;  1XS1 A;  1RNJ A;  5F9K A;  3TSL A;  2QXX A;  1MQ7 A;  3TQZ A;  1Q5U X;  2YZJ A;  3P48 A;  1EU5 A;  4GCY A;  4XJC A;  3TPW A;  2Y1T A;  1RN8 A;  1PKJ A;  3ZF3 A;  1F7N A;  3HZA A;  3TPY A;  1SM8 A;  3TS6 A;  1DUD A;  3HHQ A;  4AO5 A;  1SYL A;  1PKH A;  1PKK A;  4AOO A;  3EHW A;  1EUW A;  2OL1 A;  2D4M A;  4AOZ A;  3ECY A;  1F7O A;  1DUC A;  5EDD A;  3H6X A;  1OGH A;  1F7P A;  5CCO A;  3TRL A;  2OKB A;  2PC5 A;  1XS4 A;  1DUP A;  1SEH A;  1Q5H A;  3F4F A;  4OOP A;  3TPN A;  3ARN A;  3I93 A;  2OKD A;  1SLH A;  1XS6 A;  3ARA A;  3MBQ A;  5CCT A;  4WRK A;  3T6Y A;  2XY3 A;  2BAZ A;  1SNF A;  2WE2 A;  2HRM A;  3TRN A;  1F7D A;  2D4L A;  3T60 A;  2QLP A;  2WE3 A;  2BT1 A;  3KM3 A;  3ZF0 A;  3MDX A;  3TQ5 A;  1SMC A;  4GV8 A;  2WE1 A;  3ZEZ A;  2HXB A;  1F7K A;  1DUT A;  3SO2 A;  2HXD A;  1SIX A;  3CA9 A;  3TTA A;  3TP1 A;  2HQU A;  3ZF5 A;  3ZF2 A;  2OKE A;  2ZDC A;  4GK6 A;  5ECT A;  3ZF1 A;  2OL0 A;  1VYQ A;  3T64 A;  2J4Q A;  3T70 A;  2XX6 A;  4APZ 1;  2WE0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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