1YIJC

Crystal structure of telithromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
246
structure length
246
Chain Sequence
MQATIYDLDGNTDGEVDLPDVFETPVRSDLIGKAVRAAQANRKQDYGSDEYAGLRTPAESFGSGRGQAHVPKLDGRARRVPQAVKGRSAHPPKTEKDRSLDLNDKERQLAVRSALAATADADLVADRGHEFDRDEVPVVVSDDFEDLVKTQEVVSLLEALDVHADIDRADETKIKAGQGSARGRKYRRPASILFVTSDEPSTAARNLAGADVATASEVNTEDLAPGGAPGRLTVFTESALAEVAER
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 63
structure length 246
sequence length 246
ec nomenclature
pdb deposition date 2005-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00573 Ribosomal_L4 Ribosomal protein L4/L1 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1370.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal Protein L4; Chain: A; Ribosomal Protein L4; Chain: A; 1yijC00
1K9ME 1QVFC 1VQ7C 2OTJC 5DM7C 3CXCC 3CCUC 1VQMC 1KQSC 3CC2C 3G71C 1YJWC 1Q82E 3I56C 1KC8E 3CCLC 1Q81E 3G4SC 1YHQC 1VQOC 1S72C 1JJ2C 1VQ9C 1M1KE 1YITC 2OTLC 2QA4C 1VQ8C 1Q86E 3CCEC 1K8AE 1VQ6C 3CCRC 1YJ9C 3CPWC 3I55C 1N8RE 3CCSC 1W2BC 3CC4C 1YIJC 1Q7YE 3CCJC 3CCVC 1VQLC 3CCQC 1KD1E 3G6EC 1VQ4C 3OW2C 4V19F 3CC7C 1VQNC 3CMEC 3CCMC 1M90E 1VQKC 1QVGC 1NJIE 1YI2C 1VQPC 1K73E 1VQ5C 2QEXC 3J7YF 3CD6C 3CMAC 1DMGA 1YJNC
chains in the Genus database with same CATH superfamily
1K9ME 1QVFC 1VQ7C 2OTJC 5DM7C 3CXCC 3CCUC 1VQMC 1KQSC 3CC2C 3G71C 1YJWC 1Q82E 3I56C 1KC8E 3CCLC 1Q81E 3G4SC 1YHQC 1VQOC 1S72C 1JJ2C 1VQ9C 1M1KE 1YITC 2OTLC 2QA4C 1VQ8C 1Q86E 3CCEC 1K8AE 1VQ6C 3CCRC 1YJ9C 3CPWC 3I55C 1N8RE 3CCSC 1W2BC 3CC4C 1YIJC 1Q7YE 3CCJC 3CCVC 1VQLC 3CCQC 1KD1E 3G6EC 1VQ4C 3OW2C 4V19F 3CC7C 1VQNC 3CMEC 3CCMC 1M90E 1VQKC 1QVGC 1NJIE 1YI2C 1VQPC 1K73E 1VQ5C 2QEXC 3J7YF 3CD6C 3CMAC 1DMGA 1YJNC
chains in the Genus database with same CATH topology
1K9ME 1QVFC 1VQ7C 2OTJC 5DM7C 3CXCC 3CCUC 1VQMC 1KQSC 3CC2C 3G71C 1YJWC 1Q82E 3I56C 1KC8E 3CCLC 1Q81E 3G4SC 1YHQC 1VQOC 1S72C 1JJ2C 1VQ9C 1M1KE 1YITC 2OTLC 2QA4C 1VQ8C 1Q86E 3CCEC 1K8AE 1VQ6C 3CCRC 1YJ9C 3CPWC 3I55C 1N8RE 3CCSC 1W2BC 3CC4C 1YIJC 1Q7YE 3CCJC 3CCVC 1VQLC 3CCQC 1KD1E 3G6EC 1VQ4C 3OW2C 4V19F 3CC7C 1VQNC 3CMEC 3CCMC 1M90E 1VQKC 1QVGC 1NJIE 1YI2C 1VQPC 1K73E 1VQ5C 2QEXC 3J7YF 3CD6C 3CMAC 1DMGA 1YJNC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1K9M E;  1QVF C;  1VQ7 C;  2OTJ C;  5DM7 C;  3CXC C;  3CCU C;  1VQM C;  1KQS C;  3CC2 C;  3G71 C;  1YJW C;  1Q82 E;  3I56 C;  1KC8 E;  3CCL C;  1Q81 E;  3G4S C;  1YHQ C;  1VQO C;  1S72 C;  1JJ2 C;  1VQ9 C;  1M1K E;  1YIT C;  2OTL C;  2QA4 C;  1VQ8 C;  1Q86 E;  3CCE C;  1K8A E;  1VQ6 C;  3CCR C;  1YJ9 C;  3CPW C;  3I55 C;  1N8R E;  3CCS C;  1W2B C;  3CC4 C;  1YIJ C;  1Q7Y E;  3CCJ C;  3CCV C;  1VQL C;  3CCQ C;  1KD1 E;  3G6E C;  1VQ4 C;  3OW2 C;  4V19 F;  3CC7 C;  1VQN C;  3CME C;  3CCM C;  1M90 E;  1VQK C;  1QVG C;  1NJI E;  1YI2 C;  1VQP C;  1K73 E;  1VQ5 C;  2QEX C;  3J7Y F;  3CD6 C;  3CMA C;  1DMG A;  1YJN C; 
#chains in the Genus database with same CATH topology
 1K9M E;  1QVF C;  1VQ7 C;  2OTJ C;  5DM7 C;  3CXC C;  3CCU C;  1VQM C;  1KQS C;  3CC2 C;  3G71 C;  1YJW C;  1Q82 E;  3I56 C;  1KC8 E;  3CCL C;  1Q81 E;  3G4S C;  1YHQ C;  1VQO C;  1S72 C;  1JJ2 C;  1VQ9 C;  1M1K E;  1YIT C;  2OTL C;  2QA4 C;  1VQ8 C;  1Q86 E;  3CCE C;  1K8A E;  1VQ6 C;  3CCR C;  1YJ9 C;  3CPW C;  3I55 C;  1N8R E;  3CCS C;  1W2B C;  3CC4 C;  1YIJ C;  1Q7Y E;  3CCJ C;  3CCV C;  1VQL C;  3CCQ C;  1KD1 E;  3G6E C;  1VQ4 C;  3OW2 C;  4V19 F;  3CC7 C;  1VQN C;  3CME C;  3CCM C;  1M90 E;  1VQK C;  1QVG C;  1NJI E;  1YI2 C;  1VQP C;  1K73 E;  1VQ5 C;  2QEX C;  3J7Y F;  3CD6 C;  3CMA C;  1DMG A;  1YJN C; 
#chains in the Genus database with same CATH homology
 1K9M E;  1QVF C;  1VQ7 C;  2OTJ C;  5DM7 C;  3CXC C;  3CCU C;  1VQM C;  1KQS C;  3CC2 C;  3G71 C;  1YJW C;  1Q82 E;  3I56 C;  1KC8 E;  3CCL C;  1Q81 E;  3G4S C;  1YHQ C;  1VQO C;  1S72 C;  1JJ2 C;  1VQ9 C;  1M1K E;  1YIT C;  2OTL C;  2QA4 C;  1VQ8 C;  1Q86 E;  3CCE C;  1K8A E;  1VQ6 C;  3CCR C;  1YJ9 C;  3CPW C;  3I55 C;  1N8R E;  3CCS C;  1W2B C;  3CC4 C;  1YIJ C;  1Q7Y E;  3CCJ C;  3CCV C;  1VQL C;  3CCQ C;  1KD1 E;  3G6E C;  1VQ4 C;  3OW2 C;  4V19 F;  3CC7 C;  1VQN C;  3CME C;  3CCM C;  1M90 E;  1VQK C;  1QVG C;  1NJI E;  1YI2 C;  1VQP C;  1K73 E;  1VQ5 C;  2QEX C;  3J7Y F;  3CD6 C;  3CMA C;  1DMG A;  1YJN C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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