1YIJM

Crystal structure of telithromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
194
structure length
194
Chain Sequence
ARSAYSYIRDAWENPGDGQLAELQWQRQQEWRNEGAVERIERPTRLDKARSQGYKAKQGVIVARVSVRKGSARKRRHKAGRRSKRQGVTRITRRKDIQRVAEERASRTFPNLRVLNSYSVGQDGRQKWHEVILIDPNHPAIQNDDDLSWICADDQADRVFRGLTGAGRRNRGLSGKGKGSEKTRPSLRSNGGKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 57
structure length 194
sequence length 194
ec nomenclature
pdb deposition date 2005-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
M PF00827 Ribosomal_L15e Ribosomal L15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1120.10 Alpha Beta 3-Layer(aba) Sandwich Ribosomal protein L15e Ribosomal protein l15e 1yijM00
2OTJM 3CMAM 3CCVM 3CC2M 3CMEM 1Q81N 3CCUM 1YJWM 1QVGL 1K73N 1KD1N 1Q82N 1N8RN 1VQLM 1YIJM 3CC4M 3CCRM 2QEXM 1VQOM 1S72M 1KC8N 3CCMM 2OTLM 3CPWL 1NJIN 1VQ7M 3I56M 1VQ4M 3CXCL 1YITM 1YHQM 1YJNM 3I55M 3CC7M 1VQNM 3CCJM 3CCQM 3CCSM 1VQMM 1K8AN 3G4SM 1VQ9M 1K9MN 1M90N 1JJ2L 1VQ6M 1VQ8M 1Q86N 1VQ5M 1M1KN 2QA4M 3G6EM 1YI2M 1QVFL 3OW2L 3CCEM 3CCLM 1Q7YN 1VQKM 1YJ9M 3CD6M 1KQSL 3G71M 1VQPM 1W2BL
chains in the Genus database with same CATH superfamily
2OTJM 3CMAM 3CCVM 3CC2M 3CMEM 1Q81N 3CCUM 1YJWM 1QVGL 1K73N 1KD1N 1Q82N 1N8RN 1VQLM 1YIJM 3CC4M 3CCRM 2QEXM 1VQOM 1S72M 1KC8N 3CCMM 2OTLM 3CPWL 1NJIN 1VQ7M 3I56M 1VQ4M 3CXCL 1YITM 1YHQM 1YJNM 3I55M 3CC7M 1VQNM 3CCJM 3CCQM 3CCSM 1VQMM 1K8AN 3G4SM 1VQ9M 1K9MN 1M90N 1JJ2L 1VQ6M 1VQ8M 1Q86N 1VQ5M 1M1KN 2QA4M 3G6EM 1YI2M 1QVFL 3OW2L 3CCEM 3CCLM 1Q7YN 1VQKM 1YJ9M 3CD6M 1KQSL 3G71M 1VQPM 1W2BL
chains in the Genus database with same CATH topology
2OTJM 3CMAM 3CCVM 3CC2M 3CMEM 1Q81N 3CCUM 1YJWM 1QVGL 1K73N 1KD1N 1Q82N 1N8RN 1VQLM 1YIJM 3CC4M 3CCRM 2QEXM 1VQOM 1S72M 1KC8N 3CCMM 2OTLM 3CPWL 1NJIN 1VQ7M 3I56M 1VQ4M 3CXCL 1YITM 1YHQM 1YJNM 3I55M 3CC7M 1VQNM 3CCJM 3CCQM 3CCSM 1VQMM 1K8AN 3G4SM 1VQ9M 1K9MN 1M90N 1JJ2L 1VQ6M 1VQ8M 1Q86N 1VQ5M 1M1KN 2QA4M 3G6EM 1YI2M 1QVFL 3OW2L 3CCEM 3CCLM 1Q7YN 1VQKM 1YJ9M 3CD6M 1KQSL 3G71M 1VQPM 1W2BL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OTJ M;  3CMA M;  3CCV M;  3CC2 M;  3CME M;  1Q81 N;  3CCU M;  1YJW M;  1QVG L;  1K73 N;  1KD1 N;  1Q82 N;  1N8R N;  1VQL M;  1YIJ M;  3CC4 M;  3CCR M;  2QEX M;  1VQO M;  1S72 M;  1KC8 N;  3CCM M;  2OTL M;  3CPW L;  1NJI N;  1VQ7 M;  3I56 M;  1VQ4 M;  3CXC L;  1YIT M;  1YHQ M;  1YJN M;  3I55 M;  3CC7 M;  1VQN M;  3CCJ M;  3CCQ M;  3CCS M;  1VQM M;  1K8A N;  3G4S M;  1VQ9 M;  1K9M N;  1M90 N;  1JJ2 L;  1VQ6 M;  1VQ8 M;  1Q86 N;  1VQ5 M;  1M1K N;  2QA4 M;  3G6E M;  1YI2 M;  1QVF L;  3OW2 L;  3CCE M;  3CCL M;  1Q7Y N;  1VQK M;  1YJ9 M;  3CD6 M;  1KQS L;  3G71 M;  1VQP M;  1W2B L; 
#chains in the Genus database with same CATH topology
 2OTJ M;  3CMA M;  3CCV M;  3CC2 M;  3CME M;  1Q81 N;  3CCU M;  1YJW M;  1QVG L;  1K73 N;  1KD1 N;  1Q82 N;  1N8R N;  1VQL M;  1YIJ M;  3CC4 M;  3CCR M;  2QEX M;  1VQO M;  1S72 M;  1KC8 N;  3CCM M;  2OTL M;  3CPW L;  1NJI N;  1VQ7 M;  3I56 M;  1VQ4 M;  3CXC L;  1YIT M;  1YHQ M;  1YJN M;  3I55 M;  3CC7 M;  1VQN M;  3CCJ M;  3CCQ M;  3CCS M;  1VQM M;  1K8A N;  3G4S M;  1VQ9 M;  1K9M N;  1M90 N;  1JJ2 L;  1VQ6 M;  1VQ8 M;  1Q86 N;  1VQ5 M;  1M1K N;  2QA4 M;  3G6E M;  1YI2 M;  1QVF L;  3OW2 L;  3CCE M;  3CCL M;  1Q7Y N;  1VQK M;  1YJ9 M;  3CD6 M;  1KQS L;  3G71 M;  1VQP M;  1W2B L; 
#chains in the Genus database with same CATH homology
 2OTJ M;  3CMA M;  3CCV M;  3CC2 M;  3CME M;  1Q81 N;  3CCU M;  1YJW M;  1QVG L;  1K73 N;  1KD1 N;  1Q82 N;  1N8R N;  1VQL M;  1YIJ M;  3CC4 M;  3CCR M;  2QEX M;  1VQO M;  1S72 M;  1KC8 N;  3CCM M;  2OTL M;  3CPW L;  1NJI N;  1VQ7 M;  3I56 M;  1VQ4 M;  3CXC L;  1YIT M;  1YHQ M;  1YJN M;  3I55 M;  3CC7 M;  1VQN M;  3CCJ M;  3CCQ M;  3CCS M;  1VQM M;  1K8A N;  3G4S M;  1VQ9 M;  1K9M N;  1M90 N;  1JJ2 L;  1VQ6 M;  1VQ8 M;  1Q86 N;  1VQ5 M;  1M1K N;  2QA4 M;  3G6E M;  1YI2 M;  1QVF L;  3OW2 L;  3CCE M;  3CCL M;  1Q7Y N;  1VQK M;  1YJ9 M;  3CD6 M;  1KQS L;  3G71 M;  1VQP M;  1W2B L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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