1AWHA

Novel covalent thrombin inhibitor from plant extract
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
36
structure length
36
Chain Sequence
TFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel natural product 5,5-trans-lactone inhibitors of human alpha-thrombin: mechanism of action and structural studies.
pubmed doi rcsb
molecule tags Complex (protease/inhibitor)
molecule keywords ALPHA THROMBIN
total genus 2
structure length 36
sequence length 36
chains with identical sequence C
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 1997-10-02
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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