1C4U1

Selective non electrophilic thrombin inhibitors with cyclohexyl moieties.
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
30
structure length
30
Chain Sequence
SGEADCGLRPLFEKKSLEDKTERELLESYI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of thrombin complexed with selective non-electrophilic inhibitors having cyclohexyl moieties at P1.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords thrombin
total genus 3
structure length 30
sequence length 30
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 1999-09-25
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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