1DWEL

Crystallographic analysis at 3.0-angstroms resolution of the binding to human thrombin of four active site-directed inhibitors
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
28
structure length
28
Chain Sequence
EADCGLRPLFEKKSLEDKTERELLESYI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors.
pubmed rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Hirudo medicinalis
molecule keywords ALPHA-THROMBIN light chain
total genus 3
structure length 28
sequence length 28
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 1992-08-19
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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