1EJ5A

Solution structure of the autoinhibited conformation of wasp
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
107
structure length
107
Chain Sequence
SGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQGGSGGSQSSEGLVGALMHVMQKRSRAIHSSDEGEDQAG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein.
pubmed doi rcsb
molecule tags Blood clotting
source organism Homo sapiens
molecule keywords WISKOTT-ALDRICH SYNDROME PROTEIN
total genus 21
structure length 107
sequence length 107
ec nomenclature
pdb deposition date 2000-02-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.810.10 Alpha Beta Alpha-Beta Complex SerineThreonine-protein kinase PAK-alpha; Chain A CRIB domain 1ej5A00
1T84A 4MITE 1CEEB 2K42A 1F3MA 1EJ5A 1E0AB 2LNHA 1EESB
chains in the Genus database with same CATH superfamily
1T84A 4MITE 1CEEB 2K42A 1F3MA 1EJ5A 1E0AB 2LNHA 1EESB
chains in the Genus database with same CATH topology
1T84A 4MITE 1CEEB 2K42A 1F3MA 1EJ5A 1E0AB 2LNHA 1EESB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T84 A;  4MIT E;  1CEE B;  2K42 A;  1F3M A;  1EJ5 A;  1E0A B;  2LNH A;  1EES B; 
#chains in the Genus database with same CATH topology
 1T84 A;  4MIT E;  1CEE B;  2K42 A;  1F3M A;  1EJ5 A;  1E0A B;  2LNH A;  1EES B; 
#chains in the Genus database with same CATH homology
 1T84 A;  4MIT E;  1CEE B;  2K42 A;  1F3M A;  1EJ5 A;  1E0A B;  2LNH A;  1EES B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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