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The co-crystal structure of unliganded bovine alpha-thrombin and prethrombin-2: movement of the yppw segment and active site residues upon ligand binding
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
29
structure length
29
Chain Sequence
EADCGLRPLFEKKQVQDQTEKELFESYIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The co-crystal structure of unliganded bovine alpha-thrombin and prethrombin-2: movement of the Tyr-Pro-Pro-Trp segment and active site residues upon ligand binding.
pubmed rcsb
molecule tags Complex (blood coagulation/proenzyme)
molecule keywords ALPHA-THROMBIN
total genus 5
structure length 29
sequence length 29
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 1997-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF09396 Thrombin_light Thrombin light chain
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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