1MQ7A

Crystal structure of dutpase from mycobacterium tuberculosis (rv2697c)
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
134
structure length
134
Chain Sequence
STTLAIVRLDPGLPLPSRAHDGDAGVDLYSAEDVELAPGRRALVRTGVAVAVPFGMVGLVHPRSGLATRVGLSIVNSPGTIDAGYRGEIKVALINLDPAAPIVVHRGDRIAQLLVQRVELVELVEVSSFDEAGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
molecule keywords DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE
total genus 19
structure length 134
sequence length 134
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2002-09-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 1mq7A00
2HXBA 5F9KA 3LOJA 1SM8A 2PC5A 2OL1A 4LHRA 3TPYA 2WE0A 1EUWA 3MBQA 2QXXA 3T60A 1DUDA 2D4LA 1F7KA 2OKDA 3SO2A 2HXDA 1PKHA 1MQ7A 3TSLA 2OKEA 1SMCA 3ZF0A 1F7NA 3ARAA 3TQZA 3TQ4A 3HHQA 3TPSA 3TPWA 1DUNA 3CA9A 1XS1A 1SEHA 3C2TA 4GV8A 2D4MA 4WRKA 1DUPA 3TS6A 3TPNA 3ZF1A 2XY3A 2XCDA 4AOZA 2Y8CA 3TRNA 2WE1A 4DHKA 1SYLA 1RNJA 3T64A 3ZF4A 1RN8A 4A6AA 2BSYA 2J4QA 2XCEA 3ARNA 3ECYA 1OGHA 1EU5A 1F7RA 4GCYA 1Q5HA 1F7DA 1XS6A 1SLHA 3T6YA 2OL0A 4OOQA 1PKJA 2ZDCA 3TP1A 4APZ1 2YZJA 3ZF6A 1Q5UX 3TQ3A 1SJNA 3P48A 2PY4A 1SIXA 3MDXA 2Y1TA 3H6DA 3ZEZA 5EDDA 2BAZA 1DUCA 2D4NA 2R9QA 4AO5A 3H6XA 3TTAA 2WE2A 3C3IA 3EHWA 2HR6A 3T70A 1F7QA 3LQWA 1XS4A 3TQ5A 1F7OA 3F4FA 2HQUA 2BT1A 5CCTA 1DUTA 3GF0A 3I93A 5ECTA 4AOOA 3HZAA 3ZF5A 3ZF3A 2WE3A 2V9XA 2QLPA 2J4HA 3TRLA 3ZF2A 1VYQA 5CCOA 2HRMA 4B0HA 2XX6A 4GK6A 2OKBA 1F7PA 1PKKA 3KM3A 4OOPA 1SNFA 4XJCA
chains in the Genus database with same CATH superfamily
2HXBA 5F9KA 3LOJA 1SM8A 2PC5A 2OL1A 4LHRA 3TPYA 2WE0A 1EUWA 3MBQA 2QXXA 3T60A 1DUDA 2D4LA 1F7KA 2OKDA 3SO2A 2HXDA 1PKHA 1MQ7A 3TSLA 2OKEA 1SMCA 3ZF0A 1F7NA 3ARAA 3TQZA 3TQ4A 3HHQA 3TPSA 3TPWA 1DUNA 3CA9A 1XS1A 1SEHA 3C2TA 4GV8A 2D4MA 4WRKA 1DUPA 3TS6A 3TPNA 3ZF1A 2XY3A 2XCDA 4AOZA 2Y8CA 3TRNA 2WE1A 4DHKA 1SYLA 1RNJA 3T64A 3ZF4A 1RN8A 4A6AA 2BSYA 2J4QA 2XCEA 3ARNA 3ECYA 1OGHA 1EU5A 1F7RA 4GCYA 1Q5HA 1F7DA 1XS6A 1SLHA 3T6YA 2OL0A 4OOQA 1TULA 1PKJA 2ZDCA 3TP1A 4APZ1 2YZJA 3ZF6A 1Q5UX 3TQ3A 1SJNA 3P48A 2PY4A 1SIXA 3MDXA 2Y1TA 3H6DA 3ZEZA 5EDDA 2BAZA 1DUCA 2D4NA 2R9QA 4AO5A 3H6XA 3TTAA 2WE2A 3C3IA 3EHWA 2HR6A 3T70A 1F7QA 3LQWA 1XS4A 3TQ5A 1F7OA 3F4FA 2HQUA 2BT1A 5CCTA 1DUTA 3GF0A 3I93A 5ECTA 4AOOA 3HZAA 3ZF5A 3ZF3A 2WE3A 2V9XA 2QLPA 2J4HA 3TRLA 3ZF2A 1VYQA 5CCOA 2HRMA 4B0HA 2XX6A 4GK6A 2OKBA 1F7PA 1PKKA 3KM3A 4OOPA 1SNFA 4XJCA
chains in the Genus database with same CATH topology
2HXBA 5F9KA 3LOJA 1SM8A 2PC5A 2OL1A 4LHRA 3TPYA 2WE0A 1EUWA 3MBQA 2QXXA 3T60A 1DUDA 2D4LA 1F7KA 2OKDA 3SO2A 2HXDA 1PKHA 1MQ7A 3TSLA 2OKEA 1SMCA 3ZF0A 1F7NA 3ARAA 3TQZA 3TQ4A 3HHQA 3TPSA 3TPWA 1DUNA 3CA9A 1XS1A 1SEHA 3C2TA 4GV8A 2D4MA 4WRKA 1DUPA 3TS6A 3TPNA 3ZF1A 2XY3A 2XCDA 4AOZA 2Y8CA 3TRNA 2WE1A 4DHKA 1SYLA 1RNJA 3T64A 3ZF4A 1RN8A 4A6AA 2BSYA 2J4QA 2XCEA 3ARNA 3ECYA 1OGHA 1EU5A 1F7RA 4GCYA 1Q5HA 1F7DA 1XS6A 1SLHA 3T6YA 2OL0A 4OOQA 1PKJA 2ZDCA 3TP1A 4APZ1 2YZJA 3ZF6A 1Q5UX 3TQ3A 1SJNA 3P48A 2PY4A 1SIXA 3MDXA 2Y1TA 3H6DA 3ZEZA 5EDDA 2BAZA 1DUCA 2D4NA 2R9QA 4AO5A 3H6XA 3TTAA 2WE2A 3C3IA 3EHWA 2HR6A 3T70A 1F7QA 3LQWA 1XS4A 3TQ5A 1F7OA 3F4FA 2HQUA 2BT1A 5CCTA 1DUTA 3GF0A 3I93A 5ECTA 4AOOA 3HZAA 3ZF5A 3ZF3A 2WE3A 2V9XA 2QLPA 2J4HA 3TRLA 3ZF2A 1VYQA 5CCOA 2HRMA 4B0HA 2XX6A 4GK6A 2OKBA 1F7PA 1PKKA 3KM3A 4OOPA 1SNFA 4XJCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HXB A;  5F9K A;  3LOJ A;  1SM8 A;  2PC5 A;  2OL1 A;  4LHR A;  3TPY A;  2WE0 A;  1EUW A;  3MBQ A;  2QXX A;  3T60 A;  1DUD A;  2D4L A;  1F7K A;  2OKD A;  3SO2 A;  2HXD A;  1PKH A;  1MQ7 A;  3TSL A;  2OKE A;  1SMC A;  3ZF0 A;  1F7N A;  3ARA A;  3TQZ A;  3TQ4 A;  3HHQ A;  3TPS A;  3TPW A;  1DUN A;  3CA9 A;  1XS1 A;  1SEH A;  3C2T A;  4GV8 A;  2D4M A;  4WRK A;  1DUP A;  3TS6 A;  3TPN A;  3ZF1 A;  2XY3 A;  2XCD A;  4AOZ A;  2Y8C A;  3TRN A;  2WE1 A;  4DHK A;  1SYL A;  1RNJ A;  3T64 A;  3ZF4 A;  1RN8 A;  4A6A A;  2BSY A;  2J4Q A;  2XCE A;  3ARN A;  3ECY A;  1OGH A;  1EU5 A;  1F7R A;  4GCY A;  1Q5H A;  1F7D A;  1XS6 A;  1SLH A;  3T6Y A;  2OL0 A;  4OOQ A;  1PKJ A;  2ZDC A;  3TP1 A;  4APZ 1;  2YZJ A;  3ZF6 A;  1Q5U X;  3TQ3 A;  1SJN A;  3P48 A;  2PY4 A;  1SIX A;  3MDX A;  2Y1T A;  3H6D A;  3ZEZ A;  5EDD A;  2BAZ A;  1DUC A;  2D4N A;  2R9Q A;  4AO5 A;  3H6X A;  3TTA A;  2WE2 A;  3C3I A;  3EHW A;  2HR6 A;  3T70 A;  1F7Q A;  3LQW A;  1XS4 A;  3TQ5 A;  1F7O A;  3F4F A;  2HQU A;  2BT1 A;  5CCT A;  1DUT A;  3GF0 A;  3I93 A;  5ECT A;  4AOO A;  3HZA A;  3ZF5 A;  3ZF3 A;  2WE3 A;  2V9X A;  2QLP A;  2J4H A;  3TRL A;  3ZF2 A;  1VYQ A;  5CCO A;  2HRM A;  4B0H A;  2XX6 A;  4GK6 A;  2OKB A;  1F7P A;  1PKK A;  3KM3 A;  4OOP A;  1SNF A;  4XJC A; 
#chains in the Genus database with same CATH topology
 2HXB A;  5F9K A;  3LOJ A;  1SM8 A;  2PC5 A;  2OL1 A;  4LHR A;  3TPY A;  2WE0 A;  1EUW A;  3MBQ A;  2QXX A;  3T60 A;  1DUD A;  2D4L A;  1F7K A;  2OKD A;  3SO2 A;  2HXD A;  1PKH A;  1MQ7 A;  3TSL A;  2OKE A;  1SMC A;  3ZF0 A;  1F7N A;  3ARA A;  3TQZ A;  3TQ4 A;  3HHQ A;  3TPS A;  3TPW A;  1DUN A;  3CA9 A;  1XS1 A;  1SEH A;  3C2T A;  4GV8 A;  2D4M A;  4WRK A;  1DUP A;  3TS6 A;  3TPN A;  3ZF1 A;  2XY3 A;  2XCD A;  4AOZ A;  2Y8C A;  3TRN A;  2WE1 A;  4DHK A;  1SYL A;  1RNJ A;  3T64 A;  3ZF4 A;  1RN8 A;  4A6A A;  2BSY A;  2J4Q A;  2XCE A;  3ARN A;  3ECY A;  1OGH A;  1EU5 A;  1F7R A;  4GCY A;  1Q5H A;  1F7D A;  1XS6 A;  1SLH A;  3T6Y A;  2OL0 A;  4OOQ A;  1TUL A;  1PKJ A;  2ZDC A;  3TP1 A;  4APZ 1;  2YZJ A;  3ZF6 A;  1Q5U X;  3TQ3 A;  1SJN A;  3P48 A;  2PY4 A;  1SIX A;  3MDX A;  2Y1T A;  3H6D A;  3ZEZ A;  5EDD A;  2BAZ A;  1DUC A;  2D4N A;  2R9Q A;  4AO5 A;  3H6X A;  3TTA A;  2WE2 A;  3C3I A;  3EHW A;  2HR6 A;  3T70 A;  1F7Q A;  3LQW A;  1XS4 A;  3TQ5 A;  1F7O A;  3F4F A;  2HQU A;  2BT1 A;  5CCT A;  1DUT A;  3GF0 A;  3I93 A;  5ECT A;  4AOO A;  3HZA A;  3ZF5 A;  3ZF3 A;  2WE3 A;  2V9X A;  2QLP A;  2J4H A;  3TRL A;  3ZF2 A;  1VYQ A;  5CCO A;  2HRM A;  4B0H A;  2XX6 A;  4GK6 A;  2OKB A;  1F7P A;  1PKK A;  3KM3 A;  4OOP A;  1SNF A;  4XJC A; 
#chains in the Genus database with same CATH homology
 2HXB A;  5F9K A;  3LOJ A;  1SM8 A;  2PC5 A;  2OL1 A;  4LHR A;  3TPY A;  2WE0 A;  1EUW A;  3MBQ A;  2QXX A;  3T60 A;  1DUD A;  2D4L A;  1F7K A;  2OKD A;  3SO2 A;  2HXD A;  1PKH A;  1MQ7 A;  3TSL A;  2OKE A;  1SMC A;  3ZF0 A;  1F7N A;  3ARA A;  3TQZ A;  3TQ4 A;  3HHQ A;  3TPS A;  3TPW A;  1DUN A;  3CA9 A;  1XS1 A;  1SEH A;  3C2T A;  4GV8 A;  2D4M A;  4WRK A;  1DUP A;  3TS6 A;  3TPN A;  3ZF1 A;  2XY3 A;  2XCD A;  4AOZ A;  2Y8C A;  3TRN A;  2WE1 A;  4DHK A;  1SYL A;  1RNJ A;  3T64 A;  3ZF4 A;  1RN8 A;  4A6A A;  2BSY A;  2J4Q A;  2XCE A;  3ARN A;  3ECY A;  1OGH A;  1EU5 A;  1F7R A;  4GCY A;  1Q5H A;  1F7D A;  1XS6 A;  1SLH A;  3T6Y A;  2OL0 A;  4OOQ A;  1PKJ A;  2ZDC A;  3TP1 A;  4APZ 1;  2YZJ A;  3ZF6 A;  1Q5U X;  3TQ3 A;  1SJN A;  3P48 A;  2PY4 A;  1SIX A;  3MDX A;  2Y1T A;  3H6D A;  3ZEZ A;  5EDD A;  2BAZ A;  1DUC A;  2D4N A;  2R9Q A;  4AO5 A;  3H6X A;  3TTA A;  2WE2 A;  3C3I A;  3EHW A;  2HR6 A;  3T70 A;  1F7Q A;  3LQW A;  1XS4 A;  3TQ5 A;  1F7O A;  3F4F A;  2HQU A;  2BT1 A;  5CCT A;  1DUT A;  3GF0 A;  3I93 A;  5ECT A;  4AOO A;  3HZA A;  3ZF5 A;  3ZF3 A;  2WE3 A;  2V9X A;  2QLP A;  2J4H A;  3TRL A;  3ZF2 A;  1VYQ A;  5CCO A;  2HRM A;  4B0H A;  2XX6 A;  4GK6 A;  2OKB A;  1F7P A;  1PKK A;  3KM3 A;  4OOP A;  1SNF A;  4XJC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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