1Q5HA

Human dutp pyrophosphatase complex with dudp
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
127
structure length
127
Chain Sequence
MQLRFARLSEHATAPTRGSARAAGYDLYSAYDYTIPPMEKAVVKTDIQIALPSGCYGRVAPRSGLAAKHFIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERIFYPEIEEVQALDD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Human dUTP pyrophosphatase: uracil recognition by a Beta hairpin and active sites formed by three separate subunits
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords dUTP pyrophosphatase
total genus 21
structure length 127
sequence length 127
chains with identical sequence B, C
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2003-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 1q5hA00
1SNFA 3H6DA 5F9KA 2OKDA 2J4HA 1MQ7A 5CCOA 1DUPA 3ZEZA 3GF0A 1DUDA 2XX6A 2R9QA 1F7OA 1DUCA 3T64A 1F7DA 1SEHA 3TQ5A 1DUTA 2OKBA 3ZF2A 4LHRA 3HZAA 1RNJA 1F7RA 2BT1A 3TQZA 4OOQA 1F7NA 2Y1TA 3HHQA 2WE0A 2OL1A 4GCYA 4XJCA 3ZF6A 3SO2A 3ZF5A 3TRNA 2XY3A 2J4QA 3ZF1A 3H6XA 2XCDA 1SIXA 3C2TA 1PKKA 1F7KA 5EDDA 1VYQA 3ARNA 3MDXA 3TQ3A 1RN8A 4A6AA 4AO5A 5CCTA 2HXDA 1SJNA 1PKHA 3TS6A 3CA9A 1OGHA 1SLHA 2PY4A 3ZF0A 2XCEA 4WRKA 3P48A 1XS6A 4GV8A 3TPYA 1F7QA 3TTAA 3LQWA 1SYLA 3TPWA 4OOPA 4GK6A 2WE1A 2WE3A 3MBQA 3LOJA 3C3IA 2D4NA 3I93A 2HRMA 3TPNA 3ARAA 1SMCA 4B0HA 2PC5A 2V9XA 3TSLA 1PKJA 2HQUA 2ZDCA 3TP1A 4AOZA 2QLPA 3F4FA 1EU5A 1XS1A 2OKEA 5ECTA 4AOOA 2Y8CA 3TRLA 1F7PA 2BSYA 1XS4A 1EUWA 4DHKA 3TPSA 3ZF4A 1Q5UX 3EHWA 3T70A 3KM3A 2D4LA 2BAZA 3ECYA 3ZF3A 1SM8A 3TQ4A 2WE2A 2OL0A 4APZ1 2HR6A 2HXBA 3T6YA 2QXXA 3T60A 2D4MA 2YZJA 1DUNA 1Q5HA
chains in the Genus database with same CATH superfamily
1SNFA 3H6DA 5F9KA 2OKDA 2J4HA 1MQ7A 5CCOA 1DUPA 3ZEZA 3GF0A 1DUDA 2XX6A 2R9QA 1F7OA 1DUCA 3T64A 1F7DA 1SEHA 3TQ5A 1DUTA 2OKBA 3ZF2A 4LHRA 3HZAA 1RNJA 1F7RA 2BT1A 3TQZA 4OOQA 1F7NA 2Y1TA 3HHQA 2WE0A 2OL1A 4GCYA 4XJCA 3ZF6A 3SO2A 3ZF5A 3TRNA 2XY3A 2J4QA 3ZF1A 3H6XA 2XCDA 1SIXA 3C2TA 1PKKA 1F7KA 5EDDA 1VYQA 3ARNA 3MDXA 3TQ3A 1RN8A 4A6AA 4AO5A 5CCTA 2HXDA 1SJNA 1PKHA 3TS6A 3CA9A 1OGHA 1SLHA 2PY4A 3ZF0A 2XCEA 4WRKA 3P48A 1XS6A 4GV8A 3TPYA 1F7QA 3TTAA 3LQWA 1SYLA 3TPWA 4OOPA 4GK6A 2WE1A 2WE3A 3MBQA 3LOJA 3C3IA 2D4NA 3I93A 2HRMA 3TPNA 3ARAA 1SMCA 4B0HA 2PC5A 2V9XA 3TSLA 1PKJA 2HQUA 2ZDCA 3TP1A 4AOZA 2QLPA 3F4FA 1EU5A 1XS1A 2OKEA 5ECTA 4AOOA 2Y8CA 3TRLA 1F7PA 2BSYA 1XS4A 1TULA 1EUWA 4DHKA 3TPSA 3ZF4A 1Q5UX 3EHWA 3T70A 3KM3A 2D4LA 2BAZA 3ECYA 3ZF3A 1SM8A 3TQ4A 2WE2A 2OL0A 4APZ1 2HR6A 2HXBA 3T6YA 2QXXA 3T60A 2D4MA 2YZJA 1DUNA 1Q5HA
chains in the Genus database with same CATH topology
1SNFA 3H6DA 5F9KA 2OKDA 2J4HA 1MQ7A 5CCOA 1DUPA 3ZEZA 3GF0A 1DUDA 2XX6A 2R9QA 1F7OA 1DUCA 3T64A 1F7DA 1SEHA 3TQ5A 1DUTA 2OKBA 3ZF2A 4LHRA 3HZAA 1RNJA 1F7RA 2BT1A 3TQZA 4OOQA 1F7NA 2Y1TA 3HHQA 2WE0A 2OL1A 4GCYA 4XJCA 3ZF6A 3SO2A 3ZF5A 3TRNA 2XY3A 2J4QA 3ZF1A 3H6XA 2XCDA 1SIXA 3C2TA 1PKKA 1F7KA 5EDDA 1VYQA 3ARNA 3MDXA 3TQ3A 1RN8A 4A6AA 4AO5A 5CCTA 2HXDA 1SJNA 1PKHA 3TS6A 3CA9A 1OGHA 1SLHA 2PY4A 3ZF0A 2XCEA 4WRKA 3P48A 1XS6A 4GV8A 3TPYA 1F7QA 3TTAA 3LQWA 1SYLA 3TPWA 4OOPA 4GK6A 2WE1A 2WE3A 3MBQA 3LOJA 3C3IA 2D4NA 3I93A 2HRMA 3TPNA 3ARAA 1SMCA 4B0HA 2PC5A 2V9XA 3TSLA 1PKJA 2HQUA 2ZDCA 3TP1A 4AOZA 2QLPA 3F4FA 1EU5A 1XS1A 2OKEA 5ECTA 4AOOA 2Y8CA 3TRLA 1F7PA 2BSYA 1XS4A 1EUWA 4DHKA 3TPSA 3ZF4A 1Q5UX 3EHWA 3T70A 3KM3A 2D4LA 2BAZA 3ECYA 3ZF3A 1SM8A 3TQ4A 2WE2A 2OL0A 4APZ1 2HR6A 2HXBA 3T6YA 2QXXA 3T60A 2D4MA 2YZJA 1DUNA 1Q5HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SNF A;  3H6D A;  5F9K A;  2OKD A;  2J4H A;  1MQ7 A;  5CCO A;  1DUP A;  3ZEZ A;  3GF0 A;  1DUD A;  2XX6 A;  2R9Q A;  1F7O A;  1DUC A;  3T64 A;  1F7D A;  1SEH A;  3TQ5 A;  1DUT A;  2OKB A;  3ZF2 A;  4LHR A;  3HZA A;  1RNJ A;  1F7R A;  2BT1 A;  3TQZ A;  4OOQ A;  1F7N A;  2Y1T A;  3HHQ A;  2WE0 A;  2OL1 A;  4GCY A;  4XJC A;  3ZF6 A;  3SO2 A;  3ZF5 A;  3TRN A;  2XY3 A;  2J4Q A;  3ZF1 A;  3H6X A;  2XCD A;  1SIX A;  3C2T A;  1PKK A;  1F7K A;  5EDD A;  1VYQ A;  3ARN A;  3MDX A;  3TQ3 A;  1RN8 A;  4A6A A;  4AO5 A;  5CCT A;  2HXD A;  1SJN A;  1PKH A;  3TS6 A;  3CA9 A;  1OGH A;  1SLH A;  2PY4 A;  3ZF0 A;  2XCE A;  4WRK A;  3P48 A;  1XS6 A;  4GV8 A;  3TPY A;  1F7Q A;  3TTA A;  3LQW A;  1SYL A;  3TPW A;  4OOP A;  4GK6 A;  2WE1 A;  2WE3 A;  3MBQ A;  3LOJ A;  3C3I A;  2D4N A;  3I93 A;  2HRM A;  3TPN A;  3ARA A;  1SMC A;  4B0H A;  2PC5 A;  2V9X A;  3TSL A;  1PKJ A;  2HQU A;  2ZDC A;  3TP1 A;  4AOZ A;  2QLP A;  3F4F A;  1EU5 A;  1XS1 A;  2OKE A;  5ECT A;  4AOO A;  2Y8C A;  3TRL A;  1F7P A;  2BSY A;  1XS4 A;  1EUW A;  4DHK A;  3TPS A;  3ZF4 A;  1Q5U X;  3EHW A;  3T70 A;  3KM3 A;  2D4L A;  2BAZ A;  3ECY A;  3ZF3 A;  1SM8 A;  3TQ4 A;  2WE2 A;  2OL0 A;  4APZ 1;  2HR6 A;  2HXB A;  3T6Y A;  2QXX A;  3T60 A;  2D4M A;  2YZJ A;  1DUN A;  1Q5H A; 
#chains in the Genus database with same CATH topology
 1SNF A;  3H6D A;  5F9K A;  2OKD A;  2J4H A;  1MQ7 A;  5CCO A;  1DUP A;  3ZEZ A;  3GF0 A;  1DUD A;  2XX6 A;  2R9Q A;  1F7O A;  1DUC A;  3T64 A;  1F7D A;  1SEH A;  3TQ5 A;  1DUT A;  2OKB A;  3ZF2 A;  4LHR A;  3HZA A;  1RNJ A;  1F7R A;  2BT1 A;  3TQZ A;  4OOQ A;  1F7N A;  2Y1T A;  3HHQ A;  2WE0 A;  2OL1 A;  4GCY A;  4XJC A;  3ZF6 A;  3SO2 A;  3ZF5 A;  3TRN A;  2XY3 A;  2J4Q A;  3ZF1 A;  3H6X A;  2XCD A;  1SIX A;  3C2T A;  1PKK A;  1F7K A;  5EDD A;  1VYQ A;  3ARN A;  3MDX A;  3TQ3 A;  1RN8 A;  4A6A A;  4AO5 A;  5CCT A;  2HXD A;  1SJN A;  1PKH A;  3TS6 A;  3CA9 A;  1OGH A;  1SLH A;  2PY4 A;  3ZF0 A;  2XCE A;  4WRK A;  3P48 A;  1XS6 A;  4GV8 A;  3TPY A;  1F7Q A;  3TTA A;  3LQW A;  1SYL A;  3TPW A;  4OOP A;  4GK6 A;  2WE1 A;  2WE3 A;  3MBQ A;  3LOJ A;  3C3I A;  2D4N A;  3I93 A;  2HRM A;  3TPN A;  3ARA A;  1SMC A;  4B0H A;  2PC5 A;  2V9X A;  3TSL A;  1PKJ A;  2HQU A;  2ZDC A;  3TP1 A;  4AOZ A;  2QLP A;  3F4F A;  1EU5 A;  1XS1 A;  2OKE A;  5ECT A;  4AOO A;  2Y8C A;  3TRL A;  1F7P A;  2BSY A;  1XS4 A;  1TUL A;  1EUW A;  4DHK A;  3TPS A;  3ZF4 A;  1Q5U X;  3EHW A;  3T70 A;  3KM3 A;  2D4L A;  2BAZ A;  3ECY A;  3ZF3 A;  1SM8 A;  3TQ4 A;  2WE2 A;  2OL0 A;  4APZ 1;  2HR6 A;  2HXB A;  3T6Y A;  2QXX A;  3T60 A;  2D4M A;  2YZJ A;  1DUN A;  1Q5H A; 
#chains in the Genus database with same CATH homology
 1SNF A;  3H6D A;  5F9K A;  2OKD A;  2J4H A;  1MQ7 A;  5CCO A;  1DUP A;  3ZEZ A;  3GF0 A;  1DUD A;  2XX6 A;  2R9Q A;  1F7O A;  1DUC A;  3T64 A;  1F7D A;  1SEH A;  3TQ5 A;  1DUT A;  2OKB A;  3ZF2 A;  4LHR A;  3HZA A;  1RNJ A;  1F7R A;  2BT1 A;  3TQZ A;  4OOQ A;  1F7N A;  2Y1T A;  3HHQ A;  2WE0 A;  2OL1 A;  4GCY A;  4XJC A;  3ZF6 A;  3SO2 A;  3ZF5 A;  3TRN A;  2XY3 A;  2J4Q A;  3ZF1 A;  3H6X A;  2XCD A;  1SIX A;  3C2T A;  1PKK A;  1F7K A;  5EDD A;  1VYQ A;  3ARN A;  3MDX A;  3TQ3 A;  1RN8 A;  4A6A A;  4AO5 A;  5CCT A;  2HXD A;  1SJN A;  1PKH A;  3TS6 A;  3CA9 A;  1OGH A;  1SLH A;  2PY4 A;  3ZF0 A;  2XCE A;  4WRK A;  3P48 A;  1XS6 A;  4GV8 A;  3TPY A;  1F7Q A;  3TTA A;  3LQW A;  1SYL A;  3TPW A;  4OOP A;  4GK6 A;  2WE1 A;  2WE3 A;  3MBQ A;  3LOJ A;  3C3I A;  2D4N A;  3I93 A;  2HRM A;  3TPN A;  3ARA A;  1SMC A;  4B0H A;  2PC5 A;  2V9X A;  3TSL A;  1PKJ A;  2HQU A;  2ZDC A;  3TP1 A;  4AOZ A;  2QLP A;  3F4F A;  1EU5 A;  1XS1 A;  2OKE A;  5ECT A;  4AOO A;  2Y8C A;  3TRL A;  1F7P A;  2BSY A;  1XS4 A;  1EUW A;  4DHK A;  3TPS A;  3ZF4 A;  1Q5U X;  3EHW A;  3T70 A;  3KM3 A;  2D4L A;  2BAZ A;  3ECY A;  3ZF3 A;  1SM8 A;  3TQ4 A;  2WE2 A;  2OL0 A;  4APZ 1;  2HR6 A;  2HXB A;  3T6Y A;  2QXX A;  3T60 A;  2D4M A;  2YZJ A;  1DUN A;  1Q5H A; 
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similar chains in the Genus database (?% sequence similarity)
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