1Q5UX

Human dutp pyrophosphatase
Total Genus 20
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
131
structure length
131
Chain Sequence
HHHMQLRFARLSEHATAPTRGSARAAGYDLYSAYDYTIPPMEKAVVKTDIQIALPSGCYGRVAPRSGLAAKHFIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERIFYPEIEEVQALDDT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Human dUTP Pyrophosphatase: Uracil Recognition by a Beta Hairpin and Active Sites Formed by Three Separate Subunits
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords dUTP pyrophosphatase
total genus 20
structure length 131
sequence length 131
chains with identical sequence Y, Z
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2003-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 1q5uX00
4XJCA 2BAZA 1PKHA 1DUCA 1SMCA 2PY4A 3TPSA 4AOOA 4B0HA 2OL0A 3ZF2A 4APZ1 2QLPA 5CCTA 3TRLA 2HXBA 2XY3A 1SM8A 2HR6A 2D4LA 3ARNA 4GCYA 3TQ4A 3TP1A 4GK6A 1XS4A 4DHKA 3HHQA 2J4HA 3ECYA 5EDDA 3P48A 3H6XA 3SO2A 2ZDCA 4OOQA 2HQUA 3TQ3A 4LHRA 1VYQA 2OKDA 2R9QA 3T60A 3ZF5A 2V9XA 4AOZA 4GV8A 1PKJA 1Q5UX 3ZF1A 3LQWA 3TQZA 1F7OA 3T70A 1SNFA 2OKEA 3I93A 3TS6A 2J4QA 3TPYA 1DUDA 2PC5A 1RNJA 1SIXA 3ARAA 4A6AA 1Q5HA 2XX6A 3TTAA 3T64A 2D4MA 2BT1A 1F7DA 3MDXA 1SYLA 3C3IA 1SEHA 4WRKA 2QXXA 1F7KA 5ECTA 3TPNA 4AO5A 1F7PA 1EU5A 5F9KA 3CA9A 1EUWA 1MQ7A 2Y8CA 5CCOA 1F7QA 3LOJA 2BSYA 3ZF6A 1F7NA 3KM3A 1OGHA 2WE2A 3ZEZA 2HXDA 1DUPA 3H6DA 3ZF4A 2OL1A 3TQ5A 1RN8A 1XS6A 2XCDA 2HRMA 3C2TA 3F4FA 4OOPA 1XS1A 2WE3A 3ZF3A 3TPWA 3HZAA 1SJNA 1DUNA 2Y1TA 2OKBA 2WE1A 1DUTA 1PKKA 3MBQA 3ZF0A 3TRNA 2XCEA 2D4NA 3EHWA 1F7RA 3GF0A 3TSLA 1SLHA 2YZJA 2WE0A 3T6YA
chains in the Genus database with same CATH superfamily
4XJCA 2BAZA 1PKHA 1DUCA 1SMCA 2PY4A 3TPSA 4AOOA 4B0HA 2OL0A 3ZF2A 4APZ1 2QLPA 5CCTA 3TRLA 2HXBA 2XY3A 1SM8A 2HR6A 2D4LA 3ARNA 4GCYA 3TQ4A 3TP1A 4GK6A 1XS4A 4DHKA 3HHQA 2J4HA 3ECYA 5EDDA 3P48A 3H6XA 3SO2A 2ZDCA 4OOQA 2HQUA 3TQ3A 4LHRA 1VYQA 2OKDA 2R9QA 3T60A 3ZF5A 2V9XA 4AOZA 4GV8A 1PKJA 1Q5UX 3ZF1A 3LQWA 3TQZA 1F7OA 3T70A 1SNFA 2OKEA 3I93A 3TS6A 2J4QA 3TPYA 1DUDA 2PC5A 1RNJA 1SIXA 3ARAA 4A6AA 1Q5HA 2XX6A 3TTAA 3T64A 2D4MA 2BT1A 1F7DA 3MDXA 1SYLA 3C3IA 1SEHA 4WRKA 2QXXA 1F7KA 5ECTA 3TPNA 4AO5A 1F7PA 1EU5A 5F9KA 3CA9A 1EUWA 1MQ7A 2Y8CA 5CCOA 1F7QA 3LOJA 2BSYA 3ZF6A 1F7NA 3KM3A 1OGHA 2WE2A 3ZEZA 2HXDA 1DUPA 3H6DA 3ZF4A 1TULA 2OL1A 3TQ5A 1RN8A 1XS6A 2XCDA 2HRMA 3C2TA 3F4FA 4OOPA 1XS1A 2WE3A 3ZF3A 3TPWA 3HZAA 1SJNA 1DUNA 2Y1TA 2OKBA 2WE1A 1DUTA 1PKKA 3MBQA 3ZF0A 3TRNA 2XCEA 2D4NA 3EHWA 1F7RA 3GF0A 3TSLA 1SLHA 2YZJA 2WE0A 3T6YA
chains in the Genus database with same CATH topology
4XJCA 2BAZA 1PKHA 1DUCA 1SMCA 2PY4A 3TPSA 4AOOA 4B0HA 2OL0A 3ZF2A 4APZ1 2QLPA 5CCTA 3TRLA 2HXBA 2XY3A 1SM8A 2HR6A 2D4LA 3ARNA 4GCYA 3TQ4A 3TP1A 4GK6A 1XS4A 4DHKA 3HHQA 2J4HA 3ECYA 5EDDA 3P48A 3H6XA 3SO2A 2ZDCA 4OOQA 2HQUA 3TQ3A 4LHRA 1VYQA 2OKDA 2R9QA 3T60A 3ZF5A 2V9XA 4AOZA 4GV8A 1PKJA 1Q5UX 3ZF1A 3LQWA 3TQZA 1F7OA 3T70A 1SNFA 2OKEA 3I93A 3TS6A 2J4QA 3TPYA 1DUDA 2PC5A 1RNJA 1SIXA 3ARAA 4A6AA 1Q5HA 2XX6A 3TTAA 3T64A 2D4MA 2BT1A 1F7DA 3MDXA 1SYLA 3C3IA 1SEHA 4WRKA 2QXXA 1F7KA 5ECTA 3TPNA 4AO5A 1F7PA 1EU5A 5F9KA 3CA9A 1EUWA 1MQ7A 2Y8CA 5CCOA 1F7QA 3LOJA 2BSYA 3ZF6A 1F7NA 3KM3A 1OGHA 2WE2A 3ZEZA 2HXDA 1DUPA 3H6DA 3ZF4A 2OL1A 3TQ5A 1RN8A 1XS6A 2XCDA 2HRMA 3C2TA 3F4FA 4OOPA 1XS1A 2WE3A 3ZF3A 3TPWA 3HZAA 1SJNA 1DUNA 2Y1TA 2OKBA 2WE1A 1DUTA 1PKKA 3MBQA 3ZF0A 3TRNA 2XCEA 2D4NA 3EHWA 1F7RA 3GF0A 3TSLA 1SLHA 2YZJA 2WE0A 3T6YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XJC A;  2BAZ A;  1PKH A;  1DUC A;  1SMC A;  2PY4 A;  3TPS A;  4AOO A;  4B0H A;  2OL0 A;  3ZF2 A;  4APZ 1;  2QLP A;  5CCT A;  3TRL A;  2HXB A;  2XY3 A;  1SM8 A;  2HR6 A;  2D4L A;  3ARN A;  4GCY A;  3TQ4 A;  3TP1 A;  4GK6 A;  1XS4 A;  4DHK A;  3HHQ A;  2J4H A;  3ECY A;  5EDD A;  3P48 A;  3H6X A;  3SO2 A;  2ZDC A;  4OOQ A;  2HQU A;  3TQ3 A;  4LHR A;  1VYQ A;  2OKD A;  2R9Q A;  3T60 A;  3ZF5 A;  2V9X A;  4AOZ A;  4GV8 A;  1PKJ A;  1Q5U X;  3ZF1 A;  3LQW A;  3TQZ A;  1F7O A;  3T70 A;  1SNF A;  2OKE A;  3I93 A;  3TS6 A;  2J4Q A;  3TPY A;  1DUD A;  2PC5 A;  1RNJ A;  1SIX A;  3ARA A;  4A6A A;  1Q5H A;  2XX6 A;  3TTA A;  3T64 A;  2D4M A;  2BT1 A;  1F7D A;  3MDX A;  1SYL A;  3C3I A;  1SEH A;  4WRK A;  2QXX A;  1F7K A;  5ECT A;  3TPN A;  4AO5 A;  1F7P A;  1EU5 A;  5F9K A;  3CA9 A;  1EUW A;  1MQ7 A;  2Y8C A;  5CCO A;  1F7Q A;  3LOJ A;  2BSY A;  3ZF6 A;  1F7N A;  3KM3 A;  1OGH A;  2WE2 A;  3ZEZ A;  2HXD A;  1DUP A;  3H6D A;  3ZF4 A;  2OL1 A;  3TQ5 A;  1RN8 A;  1XS6 A;  2XCD A;  2HRM A;  3C2T A;  3F4F A;  4OOP A;  1XS1 A;  2WE3 A;  3ZF3 A;  3TPW A;  3HZA A;  1SJN A;  1DUN A;  2Y1T A;  2OKB A;  2WE1 A;  1DUT A;  1PKK A;  3MBQ A;  3ZF0 A;  3TRN A;  2XCE A;  2D4N A;  3EHW A;  1F7R A;  3GF0 A;  3TSL A;  1SLH A;  2YZJ A;  2WE0 A;  3T6Y A; 
#chains in the Genus database with same CATH topology
 4XJC A;  2BAZ A;  1PKH A;  1DUC A;  1SMC A;  2PY4 A;  3TPS A;  4AOO A;  4B0H A;  2OL0 A;  3ZF2 A;  4APZ 1;  2QLP A;  5CCT A;  3TRL A;  2HXB A;  2XY3 A;  1SM8 A;  2HR6 A;  2D4L A;  3ARN A;  4GCY A;  3TQ4 A;  3TP1 A;  4GK6 A;  1XS4 A;  4DHK A;  3HHQ A;  2J4H A;  3ECY A;  5EDD A;  3P48 A;  3H6X A;  3SO2 A;  2ZDC A;  4OOQ A;  2HQU A;  3TQ3 A;  4LHR A;  1VYQ A;  2OKD A;  2R9Q A;  3T60 A;  3ZF5 A;  2V9X A;  4AOZ A;  4GV8 A;  1PKJ A;  1Q5U X;  3ZF1 A;  3LQW A;  3TQZ A;  1F7O A;  3T70 A;  1SNF A;  2OKE A;  3I93 A;  3TS6 A;  2J4Q A;  3TPY A;  1DUD A;  2PC5 A;  1RNJ A;  1SIX A;  3ARA A;  4A6A A;  1Q5H A;  2XX6 A;  3TTA A;  3T64 A;  2D4M A;  2BT1 A;  1F7D A;  3MDX A;  1SYL A;  3C3I A;  1SEH A;  4WRK A;  2QXX A;  1F7K A;  5ECT A;  3TPN A;  4AO5 A;  1F7P A;  1EU5 A;  5F9K A;  3CA9 A;  1EUW A;  1MQ7 A;  2Y8C A;  5CCO A;  1F7Q A;  3LOJ A;  2BSY A;  3ZF6 A;  1F7N A;  3KM3 A;  1OGH A;  2WE2 A;  3ZEZ A;  2HXD A;  1DUP A;  3H6D A;  3ZF4 A;  1TUL A;  2OL1 A;  3TQ5 A;  1RN8 A;  1XS6 A;  2XCD A;  2HRM A;  3C2T A;  3F4F A;  4OOP A;  1XS1 A;  2WE3 A;  3ZF3 A;  3TPW A;  3HZA A;  1SJN A;  1DUN A;  2Y1T A;  2OKB A;  2WE1 A;  1DUT A;  1PKK A;  3MBQ A;  3ZF0 A;  3TRN A;  2XCE A;  2D4N A;  3EHW A;  1F7R A;  3GF0 A;  3TSL A;  1SLH A;  2YZJ A;  2WE0 A;  3T6Y A; 
#chains in the Genus database with same CATH homology
 4XJC A;  2BAZ A;  1PKH A;  1DUC A;  1SMC A;  2PY4 A;  3TPS A;  4AOO A;  4B0H A;  2OL0 A;  3ZF2 A;  4APZ 1;  2QLP A;  5CCT A;  3TRL A;  2HXB A;  2XY3 A;  1SM8 A;  2HR6 A;  2D4L A;  3ARN A;  4GCY A;  3TQ4 A;  3TP1 A;  4GK6 A;  1XS4 A;  4DHK A;  3HHQ A;  2J4H A;  3ECY A;  5EDD A;  3P48 A;  3H6X A;  3SO2 A;  2ZDC A;  4OOQ A;  2HQU A;  3TQ3 A;  4LHR A;  1VYQ A;  2OKD A;  2R9Q A;  3T60 A;  3ZF5 A;  2V9X A;  4AOZ A;  4GV8 A;  1PKJ A;  1Q5U X;  3ZF1 A;  3LQW A;  3TQZ A;  1F7O A;  3T70 A;  1SNF A;  2OKE A;  3I93 A;  3TS6 A;  2J4Q A;  3TPY A;  1DUD A;  2PC5 A;  1RNJ A;  1SIX A;  3ARA A;  4A6A A;  1Q5H A;  2XX6 A;  3TTA A;  3T64 A;  2D4M A;  2BT1 A;  1F7D A;  3MDX A;  1SYL A;  3C3I A;  1SEH A;  4WRK A;  2QXX A;  1F7K A;  5ECT A;  3TPN A;  4AO5 A;  1F7P A;  1EU5 A;  5F9K A;  3CA9 A;  1EUW A;  1MQ7 A;  2Y8C A;  5CCO A;  1F7Q A;  3LOJ A;  2BSY A;  3ZF6 A;  1F7N A;  3KM3 A;  1OGH A;  2WE2 A;  3ZEZ A;  2HXD A;  1DUP A;  3H6D A;  3ZF4 A;  2OL1 A;  3TQ5 A;  1RN8 A;  1XS6 A;  2XCD A;  2HRM A;  3C2T A;  3F4F A;  4OOP A;  1XS1 A;  2WE3 A;  3ZF3 A;  3TPW A;  3HZA A;  1SJN A;  1DUN A;  2Y1T A;  2OKB A;  2WE1 A;  1DUT A;  1PKK A;  3MBQ A;  3ZF0 A;  3TRN A;  2XCE A;  2D4N A;  3EHW A;  1F7R A;  3GF0 A;  3TSL A;  1SLH A;  2YZJ A;  2WE0 A;  3T6Y A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...