1RN8A

Crystal structure of dutpase complexed with substrate analogue imido-dutp
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
152
structure length
140
Chain Sequence
MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLNDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVWNRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDFRQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Catalytic Mechanism of Phosphate Ester Hydrolysis by dUTPase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Deoxyuridine 5'-triphosphate nucleotidohydrolase
total genus 22
structure length 140
sequence length 152
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2003-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 1rn8A00
1Q5UX 4XJCA 3LOJA 3TPYA 1DUCA 2WE0A 2PC5A 2BSYA 4GV8A 2D4LA 1Q5HA 3TRNA 2OKBA 2Y1TA 1DUNA 2ZDCA 2WE1A 2QXXA 4DHKA 3ZF4A 3TS6A 3ECYA 2J4QA 4OOPA 3HZAA 3TTAA 1RN8A 3P48A 3ZF2A 1F7OA 2XY3A 1PKHA 1XS1A 2BT1A 3ZEZA 1DUTA 1SM8A 1SJNA 5CCOA 3TQ3A 3TRLA 2V9XA 1MQ7A 4AOZA 2D4NA 5CCTA 1F7KA 2HQUA 3SO2A 2XX6A 3T64A 1VYQA 4AOOA 1OGHA 3GF0A 3TQ5A 1PKJA 3MDXA 3C2TA 2OKEA 3ZF5A 3TPWA 1DUPA 3ZF6A 2Y8CA 2HRMA 4GK6A 2YZJA 2D4MA 4AO5A 4LHRA 3ZF1A 1SYLA 1XS4A 2HR6A 2XCEA 3TQZA 2WE3A 4GCYA 1EUWA 4A6AA 4B0HA 1SLHA 4APZ1 3ARNA 3ZF0A 3H6XA 3ARAA 2XCDA 1F7PA 1DUDA 2PY4A 4OOQA 3TQ4A 5EDDA 3CA9A 3EHWA 2HXDA 1SIXA 3I93A 3TPSA 1F7DA 1SEHA 3HHQA 4WRKA 3H6DA 3TSLA 3T70A 2OKDA 1XS6A 2HXBA 3KM3A 1F7RA 3T6YA 2BAZA 1EU5A 3TPNA 1SMCA 2OL0A 2WE2A 5ECTA 1F7NA 3F4FA 3ZF3A 2J4HA 3TP1A 1F7QA 3C3IA 5F9KA 3T60A 3MBQA 2QLPA 1RNJA 2R9QA 1PKKA 1SNFA 3LQWA 2OL1A
chains in the Genus database with same CATH superfamily
1Q5UX 4XJCA 3LOJA 3TPYA 1DUCA 2WE0A 2PC5A 2BSYA 4GV8A 2D4LA 1Q5HA 3TRNA 2OKBA 2Y1TA 1DUNA 2ZDCA 2WE1A 2QXXA 4DHKA 3ZF4A 3TS6A 3ECYA 2J4QA 4OOPA 3HZAA 3TTAA 1RN8A 3P48A 3ZF2A 1F7OA 2XY3A 1PKHA 1XS1A 2BT1A 3ZEZA 1DUTA 1SM8A 1SJNA 5CCOA 3TQ3A 3TRLA 2V9XA 1MQ7A 4AOZA 2D4NA 5CCTA 1F7KA 2HQUA 3SO2A 2XX6A 3T64A 1VYQA 4AOOA 1OGHA 3GF0A 3TQ5A 1PKJA 3MDXA 3C2TA 2OKEA 3ZF5A 3TPWA 1DUPA 3ZF6A 2Y8CA 2HRMA 4GK6A 2YZJA 2D4MA 4AO5A 4LHRA 3ZF1A 1SYLA 1XS4A 2HR6A 2XCEA 3TQZA 2WE3A 4GCYA 1EUWA 4A6AA 4B0HA 1SLHA 4APZ1 3ARNA 3ZF0A 3H6XA 3ARAA 2XCDA 1F7PA 1DUDA 2PY4A 4OOQA 3TQ4A 5EDDA 3CA9A 3EHWA 2HXDA 1SIXA 3I93A 3TPSA 1F7DA 1SEHA 3HHQA 4WRKA 3H6DA 3TSLA 3T70A 2OKDA 1XS6A 2HXBA 3KM3A 1TULA 1F7RA 3T6YA 2BAZA 1EU5A 3TPNA 1SMCA 2OL0A 2WE2A 5ECTA 1F7NA 3F4FA 3ZF3A 2J4HA 3TP1A 1F7QA 3C3IA 5F9KA 3T60A 3MBQA 2QLPA 1RNJA 2R9QA 1PKKA 1SNFA 3LQWA 2OL1A
chains in the Genus database with same CATH topology
1Q5UX 4XJCA 3LOJA 3TPYA 1DUCA 2WE0A 2PC5A 2BSYA 4GV8A 2D4LA 1Q5HA 3TRNA 2OKBA 2Y1TA 1DUNA 2ZDCA 2WE1A 2QXXA 4DHKA 3ZF4A 3TS6A 3ECYA 2J4QA 4OOPA 3HZAA 3TTAA 1RN8A 3P48A 3ZF2A 1F7OA 2XY3A 1PKHA 1XS1A 2BT1A 3ZEZA 1DUTA 1SM8A 1SJNA 5CCOA 3TQ3A 3TRLA 2V9XA 1MQ7A 4AOZA 2D4NA 5CCTA 1F7KA 2HQUA 3SO2A 2XX6A 3T64A 1VYQA 4AOOA 1OGHA 3GF0A 3TQ5A 1PKJA 3MDXA 3C2TA 2OKEA 3ZF5A 3TPWA 1DUPA 3ZF6A 2Y8CA 2HRMA 4GK6A 2YZJA 2D4MA 4AO5A 4LHRA 3ZF1A 1SYLA 1XS4A 2HR6A 2XCEA 3TQZA 2WE3A 4GCYA 1EUWA 4A6AA 4B0HA 1SLHA 4APZ1 3ARNA 3ZF0A 3H6XA 3ARAA 2XCDA 1F7PA 1DUDA 2PY4A 4OOQA 3TQ4A 5EDDA 3CA9A 3EHWA 2HXDA 1SIXA 3I93A 3TPSA 1F7DA 1SEHA 3HHQA 4WRKA 3H6DA 3TSLA 3T70A 2OKDA 1XS6A 2HXBA 3KM3A 1F7RA 3T6YA 2BAZA 1EU5A 3TPNA 1SMCA 2OL0A 2WE2A 5ECTA 1F7NA 3F4FA 3ZF3A 2J4HA 3TP1A 1F7QA 3C3IA 5F9KA 3T60A 3MBQA 2QLPA 1RNJA 2R9QA 1PKKA 1SNFA 3LQWA 2OL1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Q5U X;  4XJC A;  3LOJ A;  3TPY A;  1DUC A;  2WE0 A;  2PC5 A;  2BSY A;  4GV8 A;  2D4L A;  1Q5H A;  3TRN A;  2OKB A;  2Y1T A;  1DUN A;  2ZDC A;  2WE1 A;  2QXX A;  4DHK A;  3ZF4 A;  3TS6 A;  3ECY A;  2J4Q A;  4OOP A;  3HZA A;  3TTA A;  1RN8 A;  3P48 A;  3ZF2 A;  1F7O A;  2XY3 A;  1PKH A;  1XS1 A;  2BT1 A;  3ZEZ A;  1DUT A;  1SM8 A;  1SJN A;  5CCO A;  3TQ3 A;  3TRL A;  2V9X A;  1MQ7 A;  4AOZ A;  2D4N A;  5CCT A;  1F7K A;  2HQU A;  3SO2 A;  2XX6 A;  3T64 A;  1VYQ A;  4AOO A;  1OGH A;  3GF0 A;  3TQ5 A;  1PKJ A;  3MDX A;  3C2T A;  2OKE A;  3ZF5 A;  3TPW A;  1DUP A;  3ZF6 A;  2Y8C A;  2HRM A;  4GK6 A;  2YZJ A;  2D4M A;  4AO5 A;  4LHR A;  3ZF1 A;  1SYL A;  1XS4 A;  2HR6 A;  2XCE A;  3TQZ A;  2WE3 A;  4GCY A;  1EUW A;  4A6A A;  4B0H A;  1SLH A;  4APZ 1;  3ARN A;  3ZF0 A;  3H6X A;  3ARA A;  2XCD A;  1F7P A;  1DUD A;  2PY4 A;  4OOQ A;  3TQ4 A;  5EDD A;  3CA9 A;  3EHW A;  2HXD A;  1SIX A;  3I93 A;  3TPS A;  1F7D A;  1SEH A;  3HHQ A;  4WRK A;  3H6D A;  3TSL A;  3T70 A;  2OKD A;  1XS6 A;  2HXB A;  3KM3 A;  1F7R A;  3T6Y A;  2BAZ A;  1EU5 A;  3TPN A;  1SMC A;  2OL0 A;  2WE2 A;  5ECT A;  1F7N A;  3F4F A;  3ZF3 A;  2J4H A;  3TP1 A;  1F7Q A;  3C3I A;  5F9K A;  3T60 A;  3MBQ A;  2QLP A;  1RNJ A;  2R9Q A;  1PKK A;  1SNF A;  3LQW A;  2OL1 A; 
#chains in the Genus database with same CATH topology
 1Q5U X;  4XJC A;  3LOJ A;  3TPY A;  1DUC A;  2WE0 A;  2PC5 A;  2BSY A;  4GV8 A;  2D4L A;  1Q5H A;  3TRN A;  2OKB A;  2Y1T A;  1DUN A;  2ZDC A;  2WE1 A;  2QXX A;  4DHK A;  3ZF4 A;  3TS6 A;  3ECY A;  2J4Q A;  4OOP A;  3HZA A;  3TTA A;  1RN8 A;  3P48 A;  3ZF2 A;  1F7O A;  2XY3 A;  1PKH A;  1XS1 A;  2BT1 A;  3ZEZ A;  1DUT A;  1SM8 A;  1SJN A;  5CCO A;  3TQ3 A;  3TRL A;  2V9X A;  1MQ7 A;  4AOZ A;  2D4N A;  5CCT A;  1F7K A;  2HQU A;  3SO2 A;  2XX6 A;  3T64 A;  1VYQ A;  4AOO A;  1OGH A;  3GF0 A;  3TQ5 A;  1PKJ A;  3MDX A;  3C2T A;  2OKE A;  3ZF5 A;  3TPW A;  1DUP A;  3ZF6 A;  2Y8C A;  2HRM A;  4GK6 A;  2YZJ A;  2D4M A;  4AO5 A;  4LHR A;  3ZF1 A;  1SYL A;  1XS4 A;  2HR6 A;  2XCE A;  3TQZ A;  2WE3 A;  4GCY A;  1EUW A;  4A6A A;  4B0H A;  1SLH A;  4APZ 1;  3ARN A;  3ZF0 A;  3H6X A;  3ARA A;  2XCD A;  1F7P A;  1DUD A;  2PY4 A;  4OOQ A;  3TQ4 A;  5EDD A;  3CA9 A;  3EHW A;  2HXD A;  1SIX A;  3I93 A;  3TPS A;  1F7D A;  1SEH A;  3HHQ A;  4WRK A;  3H6D A;  3TSL A;  3T70 A;  2OKD A;  1XS6 A;  2HXB A;  3KM3 A;  1TUL A;  1F7R A;  3T6Y A;  2BAZ A;  1EU5 A;  3TPN A;  1SMC A;  2OL0 A;  2WE2 A;  5ECT A;  1F7N A;  3F4F A;  3ZF3 A;  2J4H A;  3TP1 A;  1F7Q A;  3C3I A;  5F9K A;  3T60 A;  3MBQ A;  2QLP A;  1RNJ A;  2R9Q A;  1PKK A;  1SNF A;  3LQW A;  2OL1 A; 
#chains in the Genus database with same CATH homology
 1Q5U X;  4XJC A;  3LOJ A;  3TPY A;  1DUC A;  2WE0 A;  2PC5 A;  2BSY A;  4GV8 A;  2D4L A;  1Q5H A;  3TRN A;  2OKB A;  2Y1T A;  1DUN A;  2ZDC A;  2WE1 A;  2QXX A;  4DHK A;  3ZF4 A;  3TS6 A;  3ECY A;  2J4Q A;  4OOP A;  3HZA A;  3TTA A;  1RN8 A;  3P48 A;  3ZF2 A;  1F7O A;  2XY3 A;  1PKH A;  1XS1 A;  2BT1 A;  3ZEZ A;  1DUT A;  1SM8 A;  1SJN A;  5CCO A;  3TQ3 A;  3TRL A;  2V9X A;  1MQ7 A;  4AOZ A;  2D4N A;  5CCT A;  1F7K A;  2HQU A;  3SO2 A;  2XX6 A;  3T64 A;  1VYQ A;  4AOO A;  1OGH A;  3GF0 A;  3TQ5 A;  1PKJ A;  3MDX A;  3C2T A;  2OKE A;  3ZF5 A;  3TPW A;  1DUP A;  3ZF6 A;  2Y8C A;  2HRM A;  4GK6 A;  2YZJ A;  2D4M A;  4AO5 A;  4LHR A;  3ZF1 A;  1SYL A;  1XS4 A;  2HR6 A;  2XCE A;  3TQZ A;  2WE3 A;  4GCY A;  1EUW A;  4A6A A;  4B0H A;  1SLH A;  4APZ 1;  3ARN A;  3ZF0 A;  3H6X A;  3ARA A;  2XCD A;  1F7P A;  1DUD A;  2PY4 A;  4OOQ A;  3TQ4 A;  5EDD A;  3CA9 A;  3EHW A;  2HXD A;  1SIX A;  3I93 A;  3TPS A;  1F7D A;  1SEH A;  3HHQ A;  4WRK A;  3H6D A;  3TSL A;  3T70 A;  2OKD A;  1XS6 A;  2HXB A;  3KM3 A;  1F7R A;  3T6Y A;  2BAZ A;  1EU5 A;  3TPN A;  1SMC A;  2OL0 A;  2WE2 A;  5ECT A;  1F7N A;  3F4F A;  3ZF3 A;  2J4H A;  3TP1 A;  1F7Q A;  3C3I A;  5F9K A;  3T60 A;  3MBQ A;  2QLP A;  1RNJ A;  2R9Q A;  1PKK A;  1SNF A;  3LQW A;  2OL1 A; 
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similar chains in the Genus database (?% sequence similarity)
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