1RNJA

Crystal structure of inactive mutant dutpase complexed with substrate analogue imido-dutp
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
152
structure length
140
Chain Sequence
MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLNDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLINSDYQGQLMISVWNRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFRFRQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Catalytic Mechanism of Phosphate Ester Hydrolysis by dUTPase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Deoxyuridine 5'-triphosphate nucleotidohydrolase
total genus 22
structure length 140
sequence length 152
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2003-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 1rnjA00
3ARNA 2WE1A 3SO2A 3ZF2A 2BT1A 2PC5A 5CCTA 1MQ7A 1Q5UX 2OKDA 2D4NA 4GCYA 4APZ1 5ECTA 1SYLA 2BSYA 4GK6A 3TS6A 3T64A 3TPSA 4GV8A 1Q5HA 4OOQA 4AOZA 2D4LA 1PKJA 3H6XA 1SEHA 1F7RA 1F7PA 3TP1A 3TQ4A 3ARAA 1VYQA 1XS6A 3ZF3A 2QLPA 2PY4A 3GF0A 3HHQA 5EDDA 3T70A 2OL0A 3P48A 4LHRA 2Y1TA 3MDXA 2R9QA 4OOPA 2HQUA 3C3IA 3ZEZA 4A6AA 1RN8A 2J4HA 3KM3A 1DUCA 3ZF0A 3T60A 4B0HA 1PKKA 1PKHA 3TRNA 2QXXA 1F7OA 5F9KA 3TPWA 2WE2A 1OGHA 3T6YA 3TTAA 1SM8A 3F4FA 2OL1A 2XCDA 4XJCA 2WE3A 1F7KA 4AOOA 1SJNA 2HRMA 5CCOA 3ZF6A 2YZJA 3ZF1A 3HZAA 3TSLA 1F7NA 3TRLA 2D4MA 1EUWA 2WE0A 3LOJA 1SMCA 3C2TA 4WRKA 3ZF5A 1F7QA 3TPNA 1DUDA 3TQ5A 3H6DA 3ZF4A 2J4QA 3EHWA 1EU5A 2BAZA 2V9XA 2OKEA 3TQZA 3ECYA 3I93A 4DHKA 1SNFA 2XX6A 3LQWA 1DUNA 4AO5A 2HXBA 1RNJA 2XY3A 2Y8CA 2OKBA 3MBQA 3CA9A 1XS1A 2ZDCA 1XS4A 1DUPA 1F7DA 3TQ3A 1SLHA 2XCEA 1SIXA 1DUTA 2HR6A 2HXDA 3TPYA
chains in the Genus database with same CATH superfamily
3ARNA 2WE1A 3SO2A 3ZF2A 2BT1A 2PC5A 5CCTA 1MQ7A 1Q5UX 2OKDA 2D4NA 4GCYA 4APZ1 5ECTA 1SYLA 2BSYA 4GK6A 3TS6A 3T64A 3TPSA 4GV8A 1Q5HA 4OOQA 4AOZA 2D4LA 1PKJA 3H6XA 1SEHA 1F7RA 1F7PA 3TP1A 3TQ4A 3ARAA 1VYQA 1XS6A 3ZF3A 2QLPA 2PY4A 3GF0A 3HHQA 5EDDA 3T70A 2OL0A 3P48A 4LHRA 2Y1TA 3MDXA 2R9QA 4OOPA 2HQUA 3C3IA 3ZEZA 4A6AA 1RN8A 2J4HA 3KM3A 1DUCA 3ZF0A 3T60A 4B0HA 1PKKA 1PKHA 3TRNA 2QXXA 1F7OA 5F9KA 3TPWA 2WE2A 1OGHA 3T6YA 3TTAA 1SM8A 3F4FA 2OL1A 2XCDA 4XJCA 2WE3A 1F7KA 4AOOA 1SJNA 2HRMA 5CCOA 3ZF6A 2YZJA 3ZF1A 3HZAA 3TSLA 1F7NA 3TRLA 2D4MA 1EUWA 2WE0A 3LOJA 1SMCA 3C2TA 4WRKA 3ZF5A 1F7QA 3TPNA 1DUDA 3TQ5A 3H6DA 3ZF4A 2J4QA 3EHWA 1EU5A 2BAZA 2V9XA 2OKEA 3TQZA 3ECYA 3I93A 4DHKA 1SNFA 2XX6A 3LQWA 1DUNA 4AO5A 2HXBA 1RNJA 2XY3A 2Y8CA 2OKBA 3MBQA 3CA9A 1XS1A 2ZDCA 1XS4A 1DUPA 1F7DA 3TQ3A 1SLHA 2XCEA 1SIXA 1DUTA 2HR6A 2HXDA 1TULA 3TPYA
chains in the Genus database with same CATH topology
3ARNA 2WE1A 3SO2A 3ZF2A 2BT1A 2PC5A 5CCTA 1MQ7A 1Q5UX 2OKDA 2D4NA 4GCYA 4APZ1 5ECTA 1SYLA 2BSYA 4GK6A 3TS6A 3T64A 3TPSA 4GV8A 1Q5HA 4OOQA 4AOZA 2D4LA 1PKJA 3H6XA 1SEHA 1F7RA 1F7PA 3TP1A 3TQ4A 3ARAA 1VYQA 1XS6A 3ZF3A 2QLPA 2PY4A 3GF0A 3HHQA 5EDDA 3T70A 2OL0A 3P48A 4LHRA 2Y1TA 3MDXA 2R9QA 4OOPA 2HQUA 3C3IA 3ZEZA 4A6AA 1RN8A 2J4HA 3KM3A 1DUCA 3ZF0A 3T60A 4B0HA 1PKKA 1PKHA 3TRNA 2QXXA 1F7OA 5F9KA 3TPWA 2WE2A 1OGHA 3T6YA 3TTAA 1SM8A 3F4FA 2OL1A 2XCDA 4XJCA 2WE3A 1F7KA 4AOOA 1SJNA 2HRMA 5CCOA 3ZF6A 2YZJA 3ZF1A 3HZAA 3TSLA 1F7NA 3TRLA 2D4MA 1EUWA 2WE0A 3LOJA 1SMCA 3C2TA 4WRKA 3ZF5A 1F7QA 3TPNA 1DUDA 3TQ5A 3H6DA 3ZF4A 2J4QA 3EHWA 1EU5A 2BAZA 2V9XA 2OKEA 3TQZA 3ECYA 3I93A 4DHKA 1SNFA 2XX6A 3LQWA 1DUNA 4AO5A 2HXBA 1RNJA 2XY3A 2Y8CA 2OKBA 3MBQA 3CA9A 1XS1A 2ZDCA 1XS4A 1DUPA 1F7DA 3TQ3A 1SLHA 2XCEA 1SIXA 1DUTA 2HR6A 2HXDA 3TPYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ARN A;  2WE1 A;  3SO2 A;  3ZF2 A;  2BT1 A;  2PC5 A;  5CCT A;  1MQ7 A;  1Q5U X;  2OKD A;  2D4N A;  4GCY A;  4APZ 1;  5ECT A;  1SYL A;  2BSY A;  4GK6 A;  3TS6 A;  3T64 A;  3TPS A;  4GV8 A;  1Q5H A;  4OOQ A;  4AOZ A;  2D4L A;  1PKJ A;  3H6X A;  1SEH A;  1F7R A;  1F7P A;  3TP1 A;  3TQ4 A;  3ARA A;  1VYQ A;  1XS6 A;  3ZF3 A;  2QLP A;  2PY4 A;  3GF0 A;  3HHQ A;  5EDD A;  3T70 A;  2OL0 A;  3P48 A;  4LHR A;  2Y1T A;  3MDX A;  2R9Q A;  4OOP A;  2HQU A;  3C3I A;  3ZEZ A;  4A6A A;  1RN8 A;  2J4H A;  3KM3 A;  1DUC A;  3ZF0 A;  3T60 A;  4B0H A;  1PKK A;  1PKH A;  3TRN A;  2QXX A;  1F7O A;  5F9K A;  3TPW A;  2WE2 A;  1OGH A;  3T6Y A;  3TTA A;  1SM8 A;  3F4F A;  2OL1 A;  2XCD A;  4XJC A;  2WE3 A;  1F7K A;  4AOO A;  1SJN A;  2HRM A;  5CCO A;  3ZF6 A;  2YZJ A;  3ZF1 A;  3HZA A;  3TSL A;  1F7N A;  3TRL A;  2D4M A;  1EUW A;  2WE0 A;  3LOJ A;  1SMC A;  3C2T A;  4WRK A;  3ZF5 A;  1F7Q A;  3TPN A;  1DUD A;  3TQ5 A;  3H6D A;  3ZF4 A;  2J4Q A;  3EHW A;  1EU5 A;  2BAZ A;  2V9X A;  2OKE A;  3TQZ A;  3ECY A;  3I93 A;  4DHK A;  1SNF A;  2XX6 A;  3LQW A;  1DUN A;  4AO5 A;  2HXB A;  1RNJ A;  2XY3 A;  2Y8C A;  2OKB A;  3MBQ A;  3CA9 A;  1XS1 A;  2ZDC A;  1XS4 A;  1DUP A;  1F7D A;  3TQ3 A;  1SLH A;  2XCE A;  1SIX A;  1DUT A;  2HR6 A;  2HXD A;  3TPY A; 
#chains in the Genus database with same CATH topology
 3ARN A;  2WE1 A;  3SO2 A;  3ZF2 A;  2BT1 A;  2PC5 A;  5CCT A;  1MQ7 A;  1Q5U X;  2OKD A;  2D4N A;  4GCY A;  4APZ 1;  5ECT A;  1SYL A;  2BSY A;  4GK6 A;  3TS6 A;  3T64 A;  3TPS A;  4GV8 A;  1Q5H A;  4OOQ A;  4AOZ A;  2D4L A;  1PKJ A;  3H6X A;  1SEH A;  1F7R A;  1F7P A;  3TP1 A;  3TQ4 A;  3ARA A;  1VYQ A;  1XS6 A;  3ZF3 A;  2QLP A;  2PY4 A;  3GF0 A;  3HHQ A;  5EDD A;  3T70 A;  2OL0 A;  3P48 A;  4LHR A;  2Y1T A;  3MDX A;  2R9Q A;  4OOP A;  2HQU A;  3C3I A;  3ZEZ A;  4A6A A;  1RN8 A;  2J4H A;  3KM3 A;  1DUC A;  3ZF0 A;  3T60 A;  4B0H A;  1PKK A;  1PKH A;  3TRN A;  2QXX A;  1F7O A;  5F9K A;  3TPW A;  2WE2 A;  1OGH A;  3T6Y A;  3TTA A;  1SM8 A;  3F4F A;  2OL1 A;  2XCD A;  4XJC A;  2WE3 A;  1F7K A;  4AOO A;  1SJN A;  2HRM A;  5CCO A;  3ZF6 A;  2YZJ A;  3ZF1 A;  3HZA A;  3TSL A;  1F7N A;  3TRL A;  2D4M A;  1EUW A;  2WE0 A;  3LOJ A;  1SMC A;  3C2T A;  4WRK A;  3ZF5 A;  1F7Q A;  3TPN A;  1DUD A;  3TQ5 A;  3H6D A;  3ZF4 A;  2J4Q A;  3EHW A;  1EU5 A;  2BAZ A;  2V9X A;  2OKE A;  3TQZ A;  3ECY A;  3I93 A;  4DHK A;  1SNF A;  2XX6 A;  3LQW A;  1DUN A;  4AO5 A;  2HXB A;  1RNJ A;  2XY3 A;  2Y8C A;  2OKB A;  3MBQ A;  3CA9 A;  1XS1 A;  2ZDC A;  1XS4 A;  1DUP A;  1F7D A;  3TQ3 A;  1SLH A;  2XCE A;  1SIX A;  1DUT A;  2HR6 A;  2HXD A;  1TUL A;  3TPY A; 
#chains in the Genus database with same CATH homology
 3ARN A;  2WE1 A;  3SO2 A;  3ZF2 A;  2BT1 A;  2PC5 A;  5CCT A;  1MQ7 A;  1Q5U X;  2OKD A;  2D4N A;  4GCY A;  4APZ 1;  5ECT A;  1SYL A;  2BSY A;  4GK6 A;  3TS6 A;  3T64 A;  3TPS A;  4GV8 A;  1Q5H A;  4OOQ A;  4AOZ A;  2D4L A;  1PKJ A;  3H6X A;  1SEH A;  1F7R A;  1F7P A;  3TP1 A;  3TQ4 A;  3ARA A;  1VYQ A;  1XS6 A;  3ZF3 A;  2QLP A;  2PY4 A;  3GF0 A;  3HHQ A;  5EDD A;  3T70 A;  2OL0 A;  3P48 A;  4LHR A;  2Y1T A;  3MDX A;  2R9Q A;  4OOP A;  2HQU A;  3C3I A;  3ZEZ A;  4A6A A;  1RN8 A;  2J4H A;  3KM3 A;  1DUC A;  3ZF0 A;  3T60 A;  4B0H A;  1PKK A;  1PKH A;  3TRN A;  2QXX A;  1F7O A;  5F9K A;  3TPW A;  2WE2 A;  1OGH A;  3T6Y A;  3TTA A;  1SM8 A;  3F4F A;  2OL1 A;  2XCD A;  4XJC A;  2WE3 A;  1F7K A;  4AOO A;  1SJN A;  2HRM A;  5CCO A;  3ZF6 A;  2YZJ A;  3ZF1 A;  3HZA A;  3TSL A;  1F7N A;  3TRL A;  2D4M A;  1EUW A;  2WE0 A;  3LOJ A;  1SMC A;  3C2T A;  4WRK A;  3ZF5 A;  1F7Q A;  3TPN A;  1DUD A;  3TQ5 A;  3H6D A;  3ZF4 A;  2J4Q A;  3EHW A;  1EU5 A;  2BAZ A;  2V9X A;  2OKE A;  3TQZ A;  3ECY A;  3I93 A;  4DHK A;  1SNF A;  2XX6 A;  3LQW A;  1DUN A;  4AO5 A;  2HXB A;  1RNJ A;  2XY3 A;  2Y8C A;  2OKB A;  3MBQ A;  3CA9 A;  1XS1 A;  2ZDC A;  1XS4 A;  1DUP A;  1F7D A;  3TQ3 A;  1SLH A;  2XCE A;  1SIX A;  1DUT A;  2HR6 A;  2HXD A;  3TPY A; 
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similar chains in the Genus database (?% sequence similarity)
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