1SIXA

Mycobacterium tuberculosis dutpase complexed with magnesium and alpha,beta-imido-dutp
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
153
structure length
153
Chain Sequence
SGLVPRGSHMSTTLAIVRLDPGLPLPSRAHDGDAGVDLYSAEDVELAPGRRALVRTGVAVAVPFGMVGLVHPRSGLATRVGLSIVNSPGTIDAGYRGEIKVALINLDPAAPIVVHRGDRIAQLLVQRVELVELVEVSSFDEAGLASTSRGDGG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
molecule keywords Deoxyuridine 5'-triphosphate nucleotidohydrolase
total genus 23
structure length 153
sequence length 153
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2004-03-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 1sixA00
1VYQA 4GK6A 4OOPA 2J4QA 3T60A 3T6YA 2XCEA 3ZF3A 2J4HA 3LQWA 2QLPA 3T70A 2XCDA 3C3IA 4DHKA 1F7DA 3GF0A 4OOQA 1RNJA 3TQ4A 3TPYA 3TTAA 4AO5A 1PKKA 2OKEA 2OL0A 5F9KA 2Y8CA 1PKHA 3KM3A 3TQZA 5CCTA 3HZAA 2WE3A 5ECTA 2PC5A 3C2TA 5EDDA 3I93A 1EUWA 1F7RA 1F7PA 1XS1A 1F7NA 1SYLA 2PY4A 3TQ5A 1PKJA 3P48A 3ZF1A 3TSLA 3T64A 1SEHA 3ZEZA 4A6AA 1Q5UX 2WE0A 4AOZA 2HXBA 3ARAA 1F7OA 1MQ7A 2HQUA 2HXDA 2BAZA 3TRLA 3TPWA 1Q5HA 3LOJA 1DUNA 3F4FA 3CA9A 4GCYA 2D4LA 1SLHA 1XS6A 5CCOA 2WE2A 2OKDA 3ZF4A 4LHRA 1F7QA 3ECYA 1DUDA 3TPSA 2OL1A 1EU5A 4APZ1 3H6DA 3SO2A 4B0HA 3EHWA 2WE1A 2HR6A 2BSYA 2XY3A 2YZJA 2D4MA 1SIXA 4WRKA 3TS6A 2HRMA 3ZF0A 1OGHA 3MBQA 1RN8A 3HHQA 3ZF5A 4GV8A 1SMCA 2V9XA 2QXXA 3TQ3A 4XJCA 2Y1TA 2R9QA 3ARNA 1XS4A 3TPNA 3ZF2A 1SNFA 1DUPA 3H6XA 2ZDCA 1DUCA 1F7KA 2D4NA 1SJNA 1DUTA 3ZF6A 3TRNA 3TP1A 2XX6A 1SM8A 2BT1A 4AOOA 2OKBA 3MDXA
chains in the Genus database with same CATH superfamily
1VYQA 4GK6A 4OOPA 2J4QA 3T60A 3T6YA 2XCEA 3ZF3A 2J4HA 3LQWA 2QLPA 3T70A 2XCDA 3C3IA 4DHKA 1F7DA 3GF0A 4OOQA 1RNJA 3TQ4A 3TPYA 3TTAA 4AO5A 1PKKA 2OKEA 2OL0A 5F9KA 2Y8CA 1PKHA 3KM3A 3TQZA 5CCTA 3HZAA 2WE3A 5ECTA 2PC5A 1TULA 3C2TA 5EDDA 3I93A 1EUWA 1F7RA 1F7PA 1XS1A 1F7NA 1SYLA 2PY4A 3TQ5A 1PKJA 3P48A 3ZF1A 3TSLA 3T64A 1SEHA 3ZEZA 4A6AA 1Q5UX 2WE0A 4AOZA 2HXBA 3ARAA 1F7OA 1MQ7A 2HQUA 2HXDA 2BAZA 3TRLA 3TPWA 1Q5HA 3LOJA 1DUNA 3F4FA 3CA9A 4GCYA 2D4LA 1SLHA 1XS6A 5CCOA 2WE2A 2OKDA 3ZF4A 4LHRA 1F7QA 3ECYA 1DUDA 3TPSA 2OL1A 1EU5A 4APZ1 3H6DA 3SO2A 4B0HA 3EHWA 2WE1A 2HR6A 2BSYA 2XY3A 2YZJA 2D4MA 1SIXA 4WRKA 3TS6A 2HRMA 3ZF0A 1OGHA 3MBQA 1RN8A 3HHQA 3ZF5A 4GV8A 1SMCA 2V9XA 2QXXA 3TQ3A 4XJCA 2Y1TA 2R9QA 3ARNA 1XS4A 3TPNA 3ZF2A 1SNFA 1DUPA 3H6XA 2ZDCA 1DUCA 1F7KA 2D4NA 1SJNA 1DUTA 3ZF6A 3TRNA 3TP1A 2XX6A 1SM8A 2BT1A 4AOOA 2OKBA 3MDXA
chains in the Genus database with same CATH topology
1VYQA 4GK6A 4OOPA 2J4QA 3T60A 3T6YA 2XCEA 3ZF3A 2J4HA 3LQWA 2QLPA 3T70A 2XCDA 3C3IA 4DHKA 1F7DA 3GF0A 4OOQA 1RNJA 3TQ4A 3TPYA 3TTAA 4AO5A 1PKKA 2OKEA 2OL0A 5F9KA 2Y8CA 1PKHA 3KM3A 3TQZA 5CCTA 3HZAA 2WE3A 5ECTA 2PC5A 3C2TA 5EDDA 3I93A 1EUWA 1F7RA 1F7PA 1XS1A 1F7NA 1SYLA 2PY4A 3TQ5A 1PKJA 3P48A 3ZF1A 3TSLA 3T64A 1SEHA 3ZEZA 4A6AA 1Q5UX 2WE0A 4AOZA 2HXBA 3ARAA 1F7OA 1MQ7A 2HQUA 2HXDA 2BAZA 3TRLA 3TPWA 1Q5HA 3LOJA 1DUNA 3F4FA 3CA9A 4GCYA 2D4LA 1SLHA 1XS6A 5CCOA 2WE2A 2OKDA 3ZF4A 4LHRA 1F7QA 3ECYA 1DUDA 3TPSA 2OL1A 1EU5A 4APZ1 3H6DA 3SO2A 4B0HA 3EHWA 2WE1A 2HR6A 2BSYA 2XY3A 2YZJA 2D4MA 1SIXA 4WRKA 3TS6A 2HRMA 3ZF0A 1OGHA 3MBQA 1RN8A 3HHQA 3ZF5A 4GV8A 1SMCA 2V9XA 2QXXA 3TQ3A 4XJCA 2Y1TA 2R9QA 3ARNA 1XS4A 3TPNA 3ZF2A 1SNFA 1DUPA 3H6XA 2ZDCA 1DUCA 1F7KA 2D4NA 1SJNA 1DUTA 3ZF6A 3TRNA 3TP1A 2XX6A 1SM8A 2BT1A 4AOOA 2OKBA 3MDXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VYQ A;  4GK6 A;  4OOP A;  2J4Q A;  3T60 A;  3T6Y A;  2XCE A;  3ZF3 A;  2J4H A;  3LQW A;  2QLP A;  3T70 A;  2XCD A;  3C3I A;  4DHK A;  1F7D A;  3GF0 A;  4OOQ A;  1RNJ A;  3TQ4 A;  3TPY A;  3TTA A;  4AO5 A;  1PKK A;  2OKE A;  2OL0 A;  5F9K A;  2Y8C A;  1PKH A;  3KM3 A;  3TQZ A;  5CCT A;  3HZA A;  2WE3 A;  5ECT A;  2PC5 A;  3C2T A;  5EDD A;  3I93 A;  1EUW A;  1F7R A;  1F7P A;  1XS1 A;  1F7N A;  1SYL A;  2PY4 A;  3TQ5 A;  1PKJ A;  3P48 A;  3ZF1 A;  3TSL A;  3T64 A;  1SEH A;  3ZEZ A;  4A6A A;  1Q5U X;  2WE0 A;  4AOZ A;  2HXB A;  3ARA A;  1F7O A;  1MQ7 A;  2HQU A;  2HXD A;  2BAZ A;  3TRL A;  3TPW A;  1Q5H A;  3LOJ A;  1DUN A;  3F4F A;  3CA9 A;  4GCY A;  2D4L A;  1SLH A;  1XS6 A;  5CCO A;  2WE2 A;  2OKD A;  3ZF4 A;  4LHR A;  1F7Q A;  3ECY A;  1DUD A;  3TPS A;  2OL1 A;  1EU5 A;  4APZ 1;  3H6D A;  3SO2 A;  4B0H A;  3EHW A;  2WE1 A;  2HR6 A;  2BSY A;  2XY3 A;  2YZJ A;  2D4M A;  1SIX A;  4WRK A;  3TS6 A;  2HRM A;  3ZF0 A;  1OGH A;  3MBQ A;  1RN8 A;  3HHQ A;  3ZF5 A;  4GV8 A;  1SMC A;  2V9X A;  2QXX A;  3TQ3 A;  4XJC A;  2Y1T A;  2R9Q A;  3ARN A;  1XS4 A;  3TPN A;  3ZF2 A;  1SNF A;  1DUP A;  3H6X A;  2ZDC A;  1DUC A;  1F7K A;  2D4N A;  1SJN A;  1DUT A;  3ZF6 A;  3TRN A;  3TP1 A;  2XX6 A;  1SM8 A;  2BT1 A;  4AOO A;  2OKB A;  3MDX A; 
#chains in the Genus database with same CATH topology
 1VYQ A;  4GK6 A;  4OOP A;  2J4Q A;  3T60 A;  3T6Y A;  2XCE A;  3ZF3 A;  2J4H A;  3LQW A;  2QLP A;  3T70 A;  2XCD A;  3C3I A;  4DHK A;  1F7D A;  3GF0 A;  4OOQ A;  1RNJ A;  3TQ4 A;  3TPY A;  3TTA A;  4AO5 A;  1PKK A;  2OKE A;  2OL0 A;  5F9K A;  2Y8C A;  1PKH A;  3KM3 A;  3TQZ A;  5CCT A;  3HZA A;  2WE3 A;  5ECT A;  2PC5 A;  1TUL A;  3C2T A;  5EDD A;  3I93 A;  1EUW A;  1F7R A;  1F7P A;  1XS1 A;  1F7N A;  1SYL A;  2PY4 A;  3TQ5 A;  1PKJ A;  3P48 A;  3ZF1 A;  3TSL A;  3T64 A;  1SEH A;  3ZEZ A;  4A6A A;  1Q5U X;  2WE0 A;  4AOZ A;  2HXB A;  3ARA A;  1F7O A;  1MQ7 A;  2HQU A;  2HXD A;  2BAZ A;  3TRL A;  3TPW A;  1Q5H A;  3LOJ A;  1DUN A;  3F4F A;  3CA9 A;  4GCY A;  2D4L A;  1SLH A;  1XS6 A;  5CCO A;  2WE2 A;  2OKD A;  3ZF4 A;  4LHR A;  1F7Q A;  3ECY A;  1DUD A;  3TPS A;  2OL1 A;  1EU5 A;  4APZ 1;  3H6D A;  3SO2 A;  4B0H A;  3EHW A;  2WE1 A;  2HR6 A;  2BSY A;  2XY3 A;  2YZJ A;  2D4M A;  1SIX A;  4WRK A;  3TS6 A;  2HRM A;  3ZF0 A;  1OGH A;  3MBQ A;  1RN8 A;  3HHQ A;  3ZF5 A;  4GV8 A;  1SMC A;  2V9X A;  2QXX A;  3TQ3 A;  4XJC A;  2Y1T A;  2R9Q A;  3ARN A;  1XS4 A;  3TPN A;  3ZF2 A;  1SNF A;  1DUP A;  3H6X A;  2ZDC A;  1DUC A;  1F7K A;  2D4N A;  1SJN A;  1DUT A;  3ZF6 A;  3TRN A;  3TP1 A;  2XX6 A;  1SM8 A;  2BT1 A;  4AOO A;  2OKB A;  3MDX A; 
#chains in the Genus database with same CATH homology
 1VYQ A;  4GK6 A;  4OOP A;  2J4Q A;  3T60 A;  3T6Y A;  2XCE A;  3ZF3 A;  2J4H A;  3LQW A;  2QLP A;  3T70 A;  2XCD A;  3C3I A;  4DHK A;  1F7D A;  3GF0 A;  4OOQ A;  1RNJ A;  3TQ4 A;  3TPY A;  3TTA A;  4AO5 A;  1PKK A;  2OKE A;  2OL0 A;  5F9K A;  2Y8C A;  1PKH A;  3KM3 A;  3TQZ A;  5CCT A;  3HZA A;  2WE3 A;  5ECT A;  2PC5 A;  3C2T A;  5EDD A;  3I93 A;  1EUW A;  1F7R A;  1F7P A;  1XS1 A;  1F7N A;  1SYL A;  2PY4 A;  3TQ5 A;  1PKJ A;  3P48 A;  3ZF1 A;  3TSL A;  3T64 A;  1SEH A;  3ZEZ A;  4A6A A;  1Q5U X;  2WE0 A;  4AOZ A;  2HXB A;  3ARA A;  1F7O A;  1MQ7 A;  2HQU A;  2HXD A;  2BAZ A;  3TRL A;  3TPW A;  1Q5H A;  3LOJ A;  1DUN A;  3F4F A;  3CA9 A;  4GCY A;  2D4L A;  1SLH A;  1XS6 A;  5CCO A;  2WE2 A;  2OKD A;  3ZF4 A;  4LHR A;  1F7Q A;  3ECY A;  1DUD A;  3TPS A;  2OL1 A;  1EU5 A;  4APZ 1;  3H6D A;  3SO2 A;  4B0H A;  3EHW A;  2WE1 A;  2HR6 A;  2BSY A;  2XY3 A;  2YZJ A;  2D4M A;  1SIX A;  4WRK A;  3TS6 A;  2HRM A;  3ZF0 A;  1OGH A;  3MBQ A;  1RN8 A;  3HHQ A;  3ZF5 A;  4GV8 A;  1SMC A;  2V9X A;  2QXX A;  3TQ3 A;  4XJC A;  2Y1T A;  2R9Q A;  3ARN A;  1XS4 A;  3TPN A;  3ZF2 A;  1SNF A;  1DUP A;  3H6X A;  2ZDC A;  1DUC A;  1F7K A;  2D4N A;  1SJN A;  1DUT A;  3ZF6 A;  3TRN A;  3TP1 A;  2XX6 A;  1SM8 A;  2BT1 A;  4AOO A;  2OKB A;  3MDX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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