1SJNA

Mycobacterium tuberculosis dutpase complexed with magnesium and alpha,beta-imido-dutp
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
131
structure length
131
Chain Sequence
STTLAIVRLDPGLPLPSRAHDGDAGVDLYSAEDVELAPGRRALVRTGVAVAVPFGMVGLVHPRSGLATRVGLSIVNSPGTIDAGYRGEIKVALINLDPAAPIVVHRGDRIAQLLVQRVELVELVEVSSFDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
molecule keywords Deoxyuridine 5'-triphosphate nucleotidohydrolase
total genus 20
structure length 131
sequence length 131
chains with identical sequence B, C
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2004-03-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 1sjnA00
3TS6A 2Y1TA 4DHKA 3LQWA 3C2TA 4GCYA 1XS4A 3I93A 3MDXA 5EDDA 2V9XA 4GK6A 3ZF0A 3TQZA 3H6XA 3TSLA 4AOOA 1SJNA 3ARNA 2WE0A 2HXBA 2OKDA 1PKKA 3T64A 1PKJA 1DUPA 4GV8A 3ZF4A 4OOQA 1SM8A 3TTAA 1F7KA 1SLHA 2D4LA 1MQ7A 3GF0A 3ZF6A 3TP1A 1OGHA 1RNJA 2PC5A 1DUNA 1F7QA 5F9KA 2XCEA 3P48A 2WE1A 3HZAA 2HR6A 3HHQA 1EUWA 2D4NA 4OOPA 5ECTA 2J4HA 3TQ4A 3MBQA 2WE2A 3ZF2A 2HQUA 2OKEA 1F7OA 3ECYA 1PKHA 3ZF5A 3KM3A 2BSYA 3TRNA 3EHWA 3TPYA 2OL0A 1F7PA 1EU5A 3C3IA 2ZDCA 2BAZA 4B0HA 1XS6A 2WE3A 2HXDA 1F7RA 3TRLA 1XS1A 3T6YA 3T60A 1DUTA 1SYLA 5CCOA 2D4MA 2XY3A 2HRMA 1SNFA 3TPWA 2OL1A 3H6DA 2R9QA 1F7DA 4AO5A 1DUDA 3ZF3A 2XX6A 3TPNA 2Y8CA 1SMCA 4A6AA 1VYQA 4XJCA 3SO2A 3T70A 3F4FA 1DUCA 3TQ5A 1Q5HA 3ZF1A 2J4QA 3CA9A 3TPSA 2PY4A 2OKBA 4LHRA 3ARAA 5CCTA 1SIXA 3ZEZA 3TQ3A 2XCDA 2YZJA 2BT1A 4APZ1 3LOJA 2QLPA 1Q5UX 4WRKA 4AOZA 2QXXA 1SEHA 1RN8A 1F7NA
chains in the Genus database with same CATH superfamily
3TS6A 2Y1TA 4DHKA 3LQWA 3C2TA 4GCYA 1XS4A 3I93A 3MDXA 5EDDA 2V9XA 4GK6A 3ZF0A 3TQZA 3H6XA 3TSLA 4AOOA 1SJNA 3ARNA 2WE0A 2HXBA 2OKDA 1PKKA 3T64A 1PKJA 1DUPA 4GV8A 3ZF4A 4OOQA 1SM8A 3TTAA 1F7KA 1SLHA 2D4LA 1MQ7A 3GF0A 3ZF6A 3TP1A 1OGHA 1RNJA 2PC5A 1DUNA 1F7QA 5F9KA 2XCEA 3P48A 2WE1A 3HZAA 2HR6A 3HHQA 1EUWA 2D4NA 4OOPA 5ECTA 2J4HA 3TQ4A 3MBQA 2WE2A 3ZF2A 2HQUA 2OKEA 1F7OA 3ECYA 1PKHA 3ZF5A 3KM3A 2BSYA 3TRNA 3EHWA 3TPYA 2OL0A 1F7PA 1EU5A 3C3IA 2ZDCA 2BAZA 4B0HA 1XS6A 2WE3A 2HXDA 1F7RA 3TRLA 1XS1A 3T6YA 3T60A 1DUTA 1SYLA 5CCOA 2D4MA 2XY3A 2HRMA 1SNFA 3TPWA 2OL1A 3H6DA 2R9QA 1F7DA 4AO5A 1DUDA 3ZF3A 2XX6A 3TPNA 2Y8CA 1SMCA 4A6AA 1VYQA 4XJCA 3SO2A 3T70A 3F4FA 1DUCA 3TQ5A 1Q5HA 3ZF1A 2J4QA 3CA9A 3TPSA 2PY4A 2OKBA 4LHRA 3ARAA 5CCTA 1SIXA 3ZEZA 3TQ3A 2XCDA 1TULA 2YZJA 2BT1A 4APZ1 3LOJA 2QLPA 1Q5UX 4WRKA 4AOZA 2QXXA 1SEHA 1RN8A 1F7NA
chains in the Genus database with same CATH topology
3TS6A 2Y1TA 4DHKA 3LQWA 3C2TA 4GCYA 1XS4A 3I93A 3MDXA 5EDDA 2V9XA 4GK6A 3ZF0A 3TQZA 3H6XA 3TSLA 4AOOA 1SJNA 3ARNA 2WE0A 2HXBA 2OKDA 1PKKA 3T64A 1PKJA 1DUPA 4GV8A 3ZF4A 4OOQA 1SM8A 3TTAA 1F7KA 1SLHA 2D4LA 1MQ7A 3GF0A 3ZF6A 3TP1A 1OGHA 1RNJA 2PC5A 1DUNA 1F7QA 5F9KA 2XCEA 3P48A 2WE1A 3HZAA 2HR6A 3HHQA 1EUWA 2D4NA 4OOPA 5ECTA 2J4HA 3TQ4A 3MBQA 2WE2A 3ZF2A 2HQUA 2OKEA 1F7OA 3ECYA 1PKHA 3ZF5A 3KM3A 2BSYA 3TRNA 3EHWA 3TPYA 2OL0A 1F7PA 1EU5A 3C3IA 2ZDCA 2BAZA 4B0HA 1XS6A 2WE3A 2HXDA 1F7RA 3TRLA 1XS1A 3T6YA 3T60A 1DUTA 1SYLA 5CCOA 2D4MA 2XY3A 2HRMA 1SNFA 3TPWA 2OL1A 3H6DA 2R9QA 1F7DA 4AO5A 1DUDA 3ZF3A 2XX6A 3TPNA 2Y8CA 1SMCA 4A6AA 1VYQA 4XJCA 3SO2A 3T70A 3F4FA 1DUCA 3TQ5A 1Q5HA 3ZF1A 2J4QA 3CA9A 3TPSA 2PY4A 2OKBA 4LHRA 3ARAA 5CCTA 1SIXA 3ZEZA 3TQ3A 2XCDA 2YZJA 2BT1A 4APZ1 3LOJA 2QLPA 1Q5UX 4WRKA 4AOZA 2QXXA 1SEHA 1RN8A 1F7NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TS6 A;  2Y1T A;  4DHK A;  3LQW A;  3C2T A;  4GCY A;  1XS4 A;  3I93 A;  3MDX A;  5EDD A;  2V9X A;  4GK6 A;  3ZF0 A;  3TQZ A;  3H6X A;  3TSL A;  4AOO A;  1SJN A;  3ARN A;  2WE0 A;  2HXB A;  2OKD A;  1PKK A;  3T64 A;  1PKJ A;  1DUP A;  4GV8 A;  3ZF4 A;  4OOQ A;  1SM8 A;  3TTA A;  1F7K A;  1SLH A;  2D4L A;  1MQ7 A;  3GF0 A;  3ZF6 A;  3TP1 A;  1OGH A;  1RNJ A;  2PC5 A;  1DUN A;  1F7Q A;  5F9K A;  2XCE A;  3P48 A;  2WE1 A;  3HZA A;  2HR6 A;  3HHQ A;  1EUW A;  2D4N A;  4OOP A;  5ECT A;  2J4H A;  3TQ4 A;  3MBQ A;  2WE2 A;  3ZF2 A;  2HQU A;  2OKE A;  1F7O A;  3ECY A;  1PKH A;  3ZF5 A;  3KM3 A;  2BSY A;  3TRN A;  3EHW A;  3TPY A;  2OL0 A;  1F7P A;  1EU5 A;  3C3I A;  2ZDC A;  2BAZ A;  4B0H A;  1XS6 A;  2WE3 A;  2HXD A;  1F7R A;  3TRL A;  1XS1 A;  3T6Y A;  3T60 A;  1DUT A;  1SYL A;  5CCO A;  2D4M A;  2XY3 A;  2HRM A;  1SNF A;  3TPW A;  2OL1 A;  3H6D A;  2R9Q A;  1F7D A;  4AO5 A;  1DUD A;  3ZF3 A;  2XX6 A;  3TPN A;  2Y8C A;  1SMC A;  4A6A A;  1VYQ A;  4XJC A;  3SO2 A;  3T70 A;  3F4F A;  1DUC A;  3TQ5 A;  1Q5H A;  3ZF1 A;  2J4Q A;  3CA9 A;  3TPS A;  2PY4 A;  2OKB A;  4LHR A;  3ARA A;  5CCT A;  1SIX A;  3ZEZ A;  3TQ3 A;  2XCD A;  2YZJ A;  2BT1 A;  4APZ 1;  3LOJ A;  2QLP A;  1Q5U X;  4WRK A;  4AOZ A;  2QXX A;  1SEH A;  1RN8 A;  1F7N A; 
#chains in the Genus database with same CATH topology
 3TS6 A;  2Y1T A;  4DHK A;  3LQW A;  3C2T A;  4GCY A;  1XS4 A;  3I93 A;  3MDX A;  5EDD A;  2V9X A;  4GK6 A;  3ZF0 A;  3TQZ A;  3H6X A;  3TSL A;  4AOO A;  1SJN A;  3ARN A;  2WE0 A;  2HXB A;  2OKD A;  1PKK A;  3T64 A;  1PKJ A;  1DUP A;  4GV8 A;  3ZF4 A;  4OOQ A;  1SM8 A;  3TTA A;  1F7K A;  1SLH A;  2D4L A;  1MQ7 A;  3GF0 A;  3ZF6 A;  3TP1 A;  1OGH A;  1RNJ A;  2PC5 A;  1DUN A;  1F7Q A;  5F9K A;  2XCE A;  3P48 A;  2WE1 A;  3HZA A;  2HR6 A;  3HHQ A;  1EUW A;  2D4N A;  4OOP A;  5ECT A;  2J4H A;  3TQ4 A;  3MBQ A;  2WE2 A;  3ZF2 A;  2HQU A;  2OKE A;  1F7O A;  3ECY A;  1PKH A;  3ZF5 A;  3KM3 A;  2BSY A;  3TRN A;  3EHW A;  3TPY A;  2OL0 A;  1F7P A;  1EU5 A;  3C3I A;  2ZDC A;  2BAZ A;  4B0H A;  1XS6 A;  2WE3 A;  2HXD A;  1F7R A;  3TRL A;  1XS1 A;  3T6Y A;  3T60 A;  1DUT A;  1SYL A;  5CCO A;  2D4M A;  2XY3 A;  2HRM A;  1SNF A;  3TPW A;  2OL1 A;  3H6D A;  2R9Q A;  1F7D A;  4AO5 A;  1DUD A;  3ZF3 A;  2XX6 A;  3TPN A;  2Y8C A;  1SMC A;  4A6A A;  1VYQ A;  4XJC A;  3SO2 A;  3T70 A;  3F4F A;  1DUC A;  3TQ5 A;  1Q5H A;  3ZF1 A;  2J4Q A;  3CA9 A;  3TPS A;  2PY4 A;  2OKB A;  4LHR A;  3ARA A;  5CCT A;  1SIX A;  3ZEZ A;  3TQ3 A;  2XCD A;  1TUL A;  2YZJ A;  2BT1 A;  4APZ 1;  3LOJ A;  2QLP A;  1Q5U X;  4WRK A;  4AOZ A;  2QXX A;  1SEH A;  1RN8 A;  1F7N A; 
#chains in the Genus database with same CATH homology
 3TS6 A;  2Y1T A;  4DHK A;  3LQW A;  3C2T A;  4GCY A;  1XS4 A;  3I93 A;  3MDX A;  5EDD A;  2V9X A;  4GK6 A;  3ZF0 A;  3TQZ A;  3H6X A;  3TSL A;  4AOO A;  1SJN A;  3ARN A;  2WE0 A;  2HXB A;  2OKD A;  1PKK A;  3T64 A;  1PKJ A;  1DUP A;  4GV8 A;  3ZF4 A;  4OOQ A;  1SM8 A;  3TTA A;  1F7K A;  1SLH A;  2D4L A;  1MQ7 A;  3GF0 A;  3ZF6 A;  3TP1 A;  1OGH A;  1RNJ A;  2PC5 A;  1DUN A;  1F7Q A;  5F9K A;  2XCE A;  3P48 A;  2WE1 A;  3HZA A;  2HR6 A;  3HHQ A;  1EUW A;  2D4N A;  4OOP A;  5ECT A;  2J4H A;  3TQ4 A;  3MBQ A;  2WE2 A;  3ZF2 A;  2HQU A;  2OKE A;  1F7O A;  3ECY A;  1PKH A;  3ZF5 A;  3KM3 A;  2BSY A;  3TRN A;  3EHW A;  3TPY A;  2OL0 A;  1F7P A;  1EU5 A;  3C3I A;  2ZDC A;  2BAZ A;  4B0H A;  1XS6 A;  2WE3 A;  2HXD A;  1F7R A;  3TRL A;  1XS1 A;  3T6Y A;  3T60 A;  1DUT A;  1SYL A;  5CCO A;  2D4M A;  2XY3 A;  2HRM A;  1SNF A;  3TPW A;  2OL1 A;  3H6D A;  2R9Q A;  1F7D A;  4AO5 A;  1DUD A;  3ZF3 A;  2XX6 A;  3TPN A;  2Y8C A;  1SMC A;  4A6A A;  1VYQ A;  4XJC A;  3SO2 A;  3T70 A;  3F4F A;  1DUC A;  3TQ5 A;  1Q5H A;  3ZF1 A;  2J4Q A;  3CA9 A;  3TPS A;  2PY4 A;  2OKB A;  4LHR A;  3ARA A;  5CCT A;  1SIX A;  3ZEZ A;  3TQ3 A;  2XCD A;  2YZJ A;  2BT1 A;  4APZ 1;  3LOJ A;  2QLP A;  1Q5U X;  4WRK A;  4AOZ A;  2QXX A;  1SEH A;  1RN8 A;  1F7N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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