1SLHA

Mycobacterium tuberculosis dutpase complexed with magnesium and dudp
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
135
structure length
135
Chain Sequence
STTLAIVRLDPGLPLPSRAHDGDAGVDLYSAEDVELAPGRRALVRTGVAVAVPFGMVGLVHPRSGLATRVGLSIVNSPGTIDAGYRGEIKVALINLDPAAPIVVHRGDRIAQLLVQRVELVELVEVSSFDEAGLA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
molecule keywords Deoxyuridine 5'-triphosphate nucleotidohydrolase
total genus 20
structure length 135
sequence length 135
chains with identical sequence B, C
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2004-03-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 1slhA00
2BSYA 1Q5UX 1SYLA 3GF0A 3T60A 3LOJA 1SLHA 2HQUA 3ZF3A 3HZAA 3ZF6A 4AOZA 1F7KA 2HRMA 2HXDA 3P48A 3T70A 5EDDA 3MDXA 3T6YA 2ZDCA 2WE2A 4LHRA 3KM3A 3TTAA 3ZF0A 3C2TA 1DUDA 3TP1A 1PKHA 3ZF4A 2WE3A 1F7PA 3F4FA 2OKBA 3C3IA 2QXXA 5ECTA 3TPNA 3ZF5A 1DUPA 1XS1A 4GCYA 4OOPA 1F7NA 3TQ5A 3H6XA 2OL0A 1MQ7A 1RN8A 3HHQA 3TQZA 3ZEZA 2D4NA 2YZJA 3TPSA 4A6AA 2WE0A 2XCEA 3TQ4A 4XJCA 1SEHA 5CCTA 3ZF1A 4OOQA 3TSLA 4AO5A 5CCOA 3ARNA 1XS6A 1DUNA 3ARAA 1SMCA 3TRNA 1DUTA 2HXBA 3TS6A 2XX6A 3H6DA 1EU5A 1OGHA 4WRKA 3ECYA 1SJNA 5F9KA 1PKKA 3T64A 1F7QA 2XY3A 3CA9A 1DUCA 2D4MA 1SNFA 1PKJA 3TQ3A 2OKDA 2PC5A 2WE1A 3EHWA 1XS4A 2OKEA 2Y8CA 3LQWA 1EUWA 3SO2A 2D4LA 1SM8A 3TPYA 2PY4A 1Q5HA 2V9XA 4GV8A 1RNJA 3TRLA 2BT1A 1F7DA 4B0HA 3ZF2A 3I93A 4DHKA 4APZ1 2XCDA 1SIXA 2Y1TA 4GK6A 4AOOA 2BAZA 3TPWA 1F7OA 1F7RA 3MBQA 2HR6A 2QLPA 2J4HA 2R9QA 2J4QA 2OL1A 1VYQA
chains in the Genus database with same CATH superfamily
2BSYA 1Q5UX 1SYLA 3GF0A 3T60A 3LOJA 1SLHA 2HQUA 3ZF3A 3HZAA 3ZF6A 4AOZA 1F7KA 2HRMA 2HXDA 3P48A 3T70A 5EDDA 3MDXA 3T6YA 2ZDCA 2WE2A 4LHRA 3KM3A 3TTAA 3ZF0A 3C2TA 1DUDA 3TP1A 1PKHA 3ZF4A 2WE3A 1F7PA 3F4FA 2OKBA 3C3IA 2QXXA 5ECTA 3TPNA 3ZF5A 1DUPA 1XS1A 4GCYA 4OOPA 1F7NA 3TQ5A 3H6XA 2OL0A 1MQ7A 1RN8A 3HHQA 3TQZA 3ZEZA 2D4NA 2YZJA 3TPSA 4A6AA 2WE0A 2XCEA 3TQ4A 4XJCA 1SEHA 5CCTA 3ZF1A 4OOQA 3TSLA 4AO5A 5CCOA 3ARNA 1TULA 1XS6A 1DUNA 3ARAA 1SMCA 3TRNA 1DUTA 2HXBA 3TS6A 2XX6A 3H6DA 1EU5A 1OGHA 4WRKA 3ECYA 1SJNA 5F9KA 1PKKA 3T64A 1F7QA 2XY3A 3CA9A 1DUCA 2D4MA 1SNFA 1PKJA 3TQ3A 2OKDA 2PC5A 2WE1A 3EHWA 1XS4A 2OKEA 2Y8CA 3LQWA 1EUWA 3SO2A 2D4LA 1SM8A 3TPYA 2PY4A 1Q5HA 2V9XA 4GV8A 1RNJA 3TRLA 2BT1A 1F7DA 4B0HA 3ZF2A 3I93A 4DHKA 4APZ1 2XCDA 1SIXA 2Y1TA 4GK6A 4AOOA 2BAZA 3TPWA 1F7OA 1F7RA 3MBQA 2HR6A 2QLPA 2J4HA 2R9QA 2J4QA 2OL1A 1VYQA
chains in the Genus database with same CATH topology
2BSYA 1Q5UX 1SYLA 3GF0A 3T60A 3LOJA 1SLHA 2HQUA 3ZF3A 3HZAA 3ZF6A 4AOZA 1F7KA 2HRMA 2HXDA 3P48A 3T70A 5EDDA 3MDXA 3T6YA 2ZDCA 2WE2A 4LHRA 3KM3A 3TTAA 3ZF0A 3C2TA 1DUDA 3TP1A 1PKHA 3ZF4A 2WE3A 1F7PA 3F4FA 2OKBA 3C3IA 2QXXA 5ECTA 3TPNA 3ZF5A 1DUPA 1XS1A 4GCYA 4OOPA 1F7NA 3TQ5A 3H6XA 2OL0A 1MQ7A 1RN8A 3HHQA 3TQZA 3ZEZA 2D4NA 2YZJA 3TPSA 4A6AA 2WE0A 2XCEA 3TQ4A 4XJCA 1SEHA 5CCTA 3ZF1A 4OOQA 3TSLA 4AO5A 5CCOA 3ARNA 1XS6A 1DUNA 3ARAA 1SMCA 3TRNA 1DUTA 2HXBA 3TS6A 2XX6A 3H6DA 1EU5A 1OGHA 4WRKA 3ECYA 1SJNA 5F9KA 1PKKA 3T64A 1F7QA 2XY3A 3CA9A 1DUCA 2D4MA 1SNFA 1PKJA 3TQ3A 2OKDA 2PC5A 2WE1A 3EHWA 1XS4A 2OKEA 2Y8CA 3LQWA 1EUWA 3SO2A 2D4LA 1SM8A 3TPYA 2PY4A 1Q5HA 2V9XA 4GV8A 1RNJA 3TRLA 2BT1A 1F7DA 4B0HA 3ZF2A 3I93A 4DHKA 4APZ1 2XCDA 1SIXA 2Y1TA 4GK6A 4AOOA 2BAZA 3TPWA 1F7OA 1F7RA 3MBQA 2HR6A 2QLPA 2J4HA 2R9QA 2J4QA 2OL1A 1VYQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BSY A;  1Q5U X;  1SYL A;  3GF0 A;  3T60 A;  3LOJ A;  1SLH A;  2HQU A;  3ZF3 A;  3HZA A;  3ZF6 A;  4AOZ A;  1F7K A;  2HRM A;  2HXD A;  3P48 A;  3T70 A;  5EDD A;  3MDX A;  3T6Y A;  2ZDC A;  2WE2 A;  4LHR A;  3KM3 A;  3TTA A;  3ZF0 A;  3C2T A;  1DUD A;  3TP1 A;  1PKH A;  3ZF4 A;  2WE3 A;  1F7P A;  3F4F A;  2OKB A;  3C3I A;  2QXX A;  5ECT A;  3TPN A;  3ZF5 A;  1DUP A;  1XS1 A;  4GCY A;  4OOP A;  1F7N A;  3TQ5 A;  3H6X A;  2OL0 A;  1MQ7 A;  1RN8 A;  3HHQ A;  3TQZ A;  3ZEZ A;  2D4N A;  2YZJ A;  3TPS A;  4A6A A;  2WE0 A;  2XCE A;  3TQ4 A;  4XJC A;  1SEH A;  5CCT A;  3ZF1 A;  4OOQ A;  3TSL A;  4AO5 A;  5CCO A;  3ARN A;  1XS6 A;  1DUN A;  3ARA A;  1SMC A;  3TRN A;  1DUT A;  2HXB A;  3TS6 A;  2XX6 A;  3H6D A;  1EU5 A;  1OGH A;  4WRK A;  3ECY A;  1SJN A;  5F9K A;  1PKK A;  3T64 A;  1F7Q A;  2XY3 A;  3CA9 A;  1DUC A;  2D4M A;  1SNF A;  1PKJ A;  3TQ3 A;  2OKD A;  2PC5 A;  2WE1 A;  3EHW A;  1XS4 A;  2OKE A;  2Y8C A;  3LQW A;  1EUW A;  3SO2 A;  2D4L A;  1SM8 A;  3TPY A;  2PY4 A;  1Q5H A;  2V9X A;  4GV8 A;  1RNJ A;  3TRL A;  2BT1 A;  1F7D A;  4B0H A;  3ZF2 A;  3I93 A;  4DHK A;  4APZ 1;  2XCD A;  1SIX A;  2Y1T A;  4GK6 A;  4AOO A;  2BAZ A;  3TPW A;  1F7O A;  1F7R A;  3MBQ A;  2HR6 A;  2QLP A;  2J4H A;  2R9Q A;  2J4Q A;  2OL1 A;  1VYQ A; 
#chains in the Genus database with same CATH topology
 2BSY A;  1Q5U X;  1SYL A;  3GF0 A;  3T60 A;  3LOJ A;  1SLH A;  2HQU A;  3ZF3 A;  3HZA A;  3ZF6 A;  4AOZ A;  1F7K A;  2HRM A;  2HXD A;  3P48 A;  3T70 A;  5EDD A;  3MDX A;  3T6Y A;  2ZDC A;  2WE2 A;  4LHR A;  3KM3 A;  3TTA A;  3ZF0 A;  3C2T A;  1DUD A;  3TP1 A;  1PKH A;  3ZF4 A;  2WE3 A;  1F7P A;  3F4F A;  2OKB A;  3C3I A;  2QXX A;  5ECT A;  3TPN A;  3ZF5 A;  1DUP A;  1XS1 A;  4GCY A;  4OOP A;  1F7N A;  3TQ5 A;  3H6X A;  2OL0 A;  1MQ7 A;  1RN8 A;  3HHQ A;  3TQZ A;  3ZEZ A;  2D4N A;  2YZJ A;  3TPS A;  4A6A A;  2WE0 A;  2XCE A;  3TQ4 A;  4XJC A;  1SEH A;  5CCT A;  3ZF1 A;  4OOQ A;  3TSL A;  4AO5 A;  5CCO A;  3ARN A;  1TUL A;  1XS6 A;  1DUN A;  3ARA A;  1SMC A;  3TRN A;  1DUT A;  2HXB A;  3TS6 A;  2XX6 A;  3H6D A;  1EU5 A;  1OGH A;  4WRK A;  3ECY A;  1SJN A;  5F9K A;  1PKK A;  3T64 A;  1F7Q A;  2XY3 A;  3CA9 A;  1DUC A;  2D4M A;  1SNF A;  1PKJ A;  3TQ3 A;  2OKD A;  2PC5 A;  2WE1 A;  3EHW A;  1XS4 A;  2OKE A;  2Y8C A;  3LQW A;  1EUW A;  3SO2 A;  2D4L A;  1SM8 A;  3TPY A;  2PY4 A;  1Q5H A;  2V9X A;  4GV8 A;  1RNJ A;  3TRL A;  2BT1 A;  1F7D A;  4B0H A;  3ZF2 A;  3I93 A;  4DHK A;  4APZ 1;  2XCD A;  1SIX A;  2Y1T A;  4GK6 A;  4AOO A;  2BAZ A;  3TPW A;  1F7O A;  1F7R A;  3MBQ A;  2HR6 A;  2QLP A;  2J4H A;  2R9Q A;  2J4Q A;  2OL1 A;  1VYQ A; 
#chains in the Genus database with same CATH homology
 2BSY A;  1Q5U X;  1SYL A;  3GF0 A;  3T60 A;  3LOJ A;  1SLH A;  2HQU A;  3ZF3 A;  3HZA A;  3ZF6 A;  4AOZ A;  1F7K A;  2HRM A;  2HXD A;  3P48 A;  3T70 A;  5EDD A;  3MDX A;  3T6Y A;  2ZDC A;  2WE2 A;  4LHR A;  3KM3 A;  3TTA A;  3ZF0 A;  3C2T A;  1DUD A;  3TP1 A;  1PKH A;  3ZF4 A;  2WE3 A;  1F7P A;  3F4F A;  2OKB A;  3C3I A;  2QXX A;  5ECT A;  3TPN A;  3ZF5 A;  1DUP A;  1XS1 A;  4GCY A;  4OOP A;  1F7N A;  3TQ5 A;  3H6X A;  2OL0 A;  1MQ7 A;  1RN8 A;  3HHQ A;  3TQZ A;  3ZEZ A;  2D4N A;  2YZJ A;  3TPS A;  4A6A A;  2WE0 A;  2XCE A;  3TQ4 A;  4XJC A;  1SEH A;  5CCT A;  3ZF1 A;  4OOQ A;  3TSL A;  4AO5 A;  5CCO A;  3ARN A;  1XS6 A;  1DUN A;  3ARA A;  1SMC A;  3TRN A;  1DUT A;  2HXB A;  3TS6 A;  2XX6 A;  3H6D A;  1EU5 A;  1OGH A;  4WRK A;  3ECY A;  1SJN A;  5F9K A;  1PKK A;  3T64 A;  1F7Q A;  2XY3 A;  3CA9 A;  1DUC A;  2D4M A;  1SNF A;  1PKJ A;  3TQ3 A;  2OKD A;  2PC5 A;  2WE1 A;  3EHW A;  1XS4 A;  2OKE A;  2Y8C A;  3LQW A;  1EUW A;  3SO2 A;  2D4L A;  1SM8 A;  3TPY A;  2PY4 A;  1Q5H A;  2V9X A;  4GV8 A;  1RNJ A;  3TRL A;  2BT1 A;  1F7D A;  4B0H A;  3ZF2 A;  3I93 A;  4DHK A;  4APZ 1;  2XCD A;  1SIX A;  2Y1T A;  4GK6 A;  4AOO A;  2BAZ A;  3TPW A;  1F7O A;  1F7R A;  3MBQ A;  2HR6 A;  2QLP A;  2J4H A;  2R9Q A;  2J4Q A;  2OL1 A;  1VYQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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