1SNFA

Mycobacterium tuberculosis dutpase complexed with magnesium and deoxyuridine 5'-monophosphate
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
131
structure length
131
Chain Sequence
STTLAIVRLDPGLPLPSRAHDGDAGVDLYSAEDVELAPGRRALVRTGVAVAVPFGMVGLVHPRSGLATRVGLSIVNSPGTIDAGYRGEIKVALINLDPAAPIVVHRGDRIAQLLVQRVELVELVEVSSFDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
molecule keywords Deoxyuridine 5'-triphosphate nucleotidohydrolase
total genus 20
structure length 131
sequence length 131
chains with identical sequence B, C
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2004-03-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 1snfA00
2XCEA 1DUDA 1EU5A 3LOJA 1SNFA 2Y8CA 3TQ4A 3SO2A 2HR6A 4LHRA 3KM3A 3EHWA 4DHKA 4AOZA 2OKEA 2D4NA 1SEHA 5ECTA 2YZJA 3H6XA 2PY4A 4GCYA 3TQ3A 1RN8A 2D4MA 3CA9A 2PC5A 2BT1A 2R9QA 4AOOA 3ECYA 1F7DA 1DUCA 2OL0A 1SLHA 4B0HA 1VYQA 3ZF5A 2HRMA 1F7RA 1F7NA 3I93A 2WE0A 2D4LA 3ZEZA 4GV8A 3TRLA 5EDDA 1EUWA 2WE3A 2HXDA 1PKJA 2XCDA 2OKDA 3HHQA 2J4HA 1Q5UX 3T60A 2XX6A 3MBQA 2ZDCA 2BAZA 5F9KA 3ZF1A 3TPSA 3HZAA 3T6YA 2QLPA 2J4QA 2QXXA 3ARNA 1SJNA 1SYLA 3ZF3A 1SMCA 3TQZA 4XJCA 1OGHA 3T70A 3TPWA 1MQ7A 3ARAA 3MDXA 3TS6A 1PKHA 5CCOA 1XS6A 2OKBA 3P48A 1XS4A 3TPNA 4AO5A 2V9XA 1PKKA 3TQ5A 2WE1A 1SIXA 3TTAA 4WRKA 3TPYA 3ZF0A 3TP1A 4APZ1 2OL1A 3T64A 3ZF2A 2BSYA 2XY3A 1RNJA 2Y1TA 1XS1A 3C2TA 4GK6A 3F4FA 2HXBA 1F7QA 1DUPA 3H6DA 2HQUA 1DUNA 1SM8A 3LQWA 1F7KA 3GF0A 3ZF6A 2WE2A 1F7PA 1F7OA 4A6AA 1DUTA 3TSLA 4OOQA 3TRNA 1Q5HA 3ZF4A 3C3IA 4OOPA 5CCTA
chains in the Genus database with same CATH superfamily
2XCEA 1DUDA 1EU5A 3LOJA 1SNFA 2Y8CA 3TQ4A 3SO2A 2HR6A 4LHRA 3KM3A 3EHWA 4DHKA 4AOZA 2OKEA 2D4NA 1SEHA 5ECTA 2YZJA 3H6XA 2PY4A 4GCYA 3TQ3A 1RN8A 2D4MA 3CA9A 2PC5A 2BT1A 2R9QA 4AOOA 3ECYA 1F7DA 1DUCA 2OL0A 1SLHA 4B0HA 1VYQA 3ZF5A 2HRMA 1F7RA 1F7NA 1TULA 3I93A 2WE0A 2D4LA 3ZEZA 4GV8A 3TRLA 5EDDA 1EUWA 2WE3A 2HXDA 1PKJA 2XCDA 2OKDA 3HHQA 2J4HA 1Q5UX 3T60A 2XX6A 3MBQA 2ZDCA 2BAZA 5F9KA 3ZF1A 3TPSA 3HZAA 3T6YA 2QLPA 2J4QA 2QXXA 3ARNA 1SJNA 1SYLA 3ZF3A 1SMCA 3TQZA 4XJCA 1OGHA 3T70A 3TPWA 1MQ7A 3ARAA 3MDXA 3TS6A 1PKHA 5CCOA 1XS6A 2OKBA 3P48A 1XS4A 3TPNA 4AO5A 2V9XA 1PKKA 3TQ5A 2WE1A 1SIXA 3TTAA 4WRKA 3TPYA 3ZF0A 3TP1A 4APZ1 2OL1A 3T64A 3ZF2A 2BSYA 2XY3A 1RNJA 2Y1TA 1XS1A 3C2TA 4GK6A 3F4FA 2HXBA 1F7QA 1DUPA 3H6DA 2HQUA 1DUNA 1SM8A 3LQWA 1F7KA 3GF0A 3ZF6A 2WE2A 1F7PA 1F7OA 4A6AA 1DUTA 3TSLA 4OOQA 3TRNA 1Q5HA 3ZF4A 3C3IA 4OOPA 5CCTA
chains in the Genus database with same CATH topology
2XCEA 1DUDA 1EU5A 3LOJA 1SNFA 2Y8CA 3TQ4A 3SO2A 2HR6A 4LHRA 3KM3A 3EHWA 4DHKA 4AOZA 2OKEA 2D4NA 1SEHA 5ECTA 2YZJA 3H6XA 2PY4A 4GCYA 3TQ3A 1RN8A 2D4MA 3CA9A 2PC5A 2BT1A 2R9QA 4AOOA 3ECYA 1F7DA 1DUCA 2OL0A 1SLHA 4B0HA 1VYQA 3ZF5A 2HRMA 1F7RA 1F7NA 3I93A 2WE0A 2D4LA 3ZEZA 4GV8A 3TRLA 5EDDA 1EUWA 2WE3A 2HXDA 1PKJA 2XCDA 2OKDA 3HHQA 2J4HA 1Q5UX 3T60A 2XX6A 3MBQA 2ZDCA 2BAZA 5F9KA 3ZF1A 3TPSA 3HZAA 3T6YA 2QLPA 2J4QA 2QXXA 3ARNA 1SJNA 1SYLA 3ZF3A 1SMCA 3TQZA 4XJCA 1OGHA 3T70A 3TPWA 1MQ7A 3ARAA 3MDXA 3TS6A 1PKHA 5CCOA 1XS6A 2OKBA 3P48A 1XS4A 3TPNA 4AO5A 2V9XA 1PKKA 3TQ5A 2WE1A 1SIXA 3TTAA 4WRKA 3TPYA 3ZF0A 3TP1A 4APZ1 2OL1A 3T64A 3ZF2A 2BSYA 2XY3A 1RNJA 2Y1TA 1XS1A 3C2TA 4GK6A 3F4FA 2HXBA 1F7QA 1DUPA 3H6DA 2HQUA 1DUNA 1SM8A 3LQWA 1F7KA 3GF0A 3ZF6A 2WE2A 1F7PA 1F7OA 4A6AA 1DUTA 3TSLA 4OOQA 3TRNA 1Q5HA 3ZF4A 3C3IA 4OOPA 5CCTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XCE A;  1DUD A;  1EU5 A;  3LOJ A;  1SNF A;  2Y8C A;  3TQ4 A;  3SO2 A;  2HR6 A;  4LHR A;  3KM3 A;  3EHW A;  4DHK A;  4AOZ A;  2OKE A;  2D4N A;  1SEH A;  5ECT A;  2YZJ A;  3H6X A;  2PY4 A;  4GCY A;  3TQ3 A;  1RN8 A;  2D4M A;  3CA9 A;  2PC5 A;  2BT1 A;  2R9Q A;  4AOO A;  3ECY A;  1F7D A;  1DUC A;  2OL0 A;  1SLH A;  4B0H A;  1VYQ A;  3ZF5 A;  2HRM A;  1F7R A;  1F7N A;  3I93 A;  2WE0 A;  2D4L A;  3ZEZ A;  4GV8 A;  3TRL A;  5EDD A;  1EUW A;  2WE3 A;  2HXD A;  1PKJ A;  2XCD A;  2OKD A;  3HHQ A;  2J4H A;  1Q5U X;  3T60 A;  2XX6 A;  3MBQ A;  2ZDC A;  2BAZ A;  5F9K A;  3ZF1 A;  3TPS A;  3HZA A;  3T6Y A;  2QLP A;  2J4Q A;  2QXX A;  3ARN A;  1SJN A;  1SYL A;  3ZF3 A;  1SMC A;  3TQZ A;  4XJC A;  1OGH A;  3T70 A;  3TPW A;  1MQ7 A;  3ARA A;  3MDX A;  3TS6 A;  1PKH A;  5CCO A;  1XS6 A;  2OKB A;  3P48 A;  1XS4 A;  3TPN A;  4AO5 A;  2V9X A;  1PKK A;  3TQ5 A;  2WE1 A;  1SIX A;  3TTA A;  4WRK A;  3TPY A;  3ZF0 A;  3TP1 A;  4APZ 1;  2OL1 A;  3T64 A;  3ZF2 A;  2BSY A;  2XY3 A;  1RNJ A;  2Y1T A;  1XS1 A;  3C2T A;  4GK6 A;  3F4F A;  2HXB A;  1F7Q A;  1DUP A;  3H6D A;  2HQU A;  1DUN A;  1SM8 A;  3LQW A;  1F7K A;  3GF0 A;  3ZF6 A;  2WE2 A;  1F7P A;  1F7O A;  4A6A A;  1DUT A;  3TSL A;  4OOQ A;  3TRN A;  1Q5H A;  3ZF4 A;  3C3I A;  4OOP A;  5CCT A; 
#chains in the Genus database with same CATH topology
 2XCE A;  1DUD A;  1EU5 A;  3LOJ A;  1SNF A;  2Y8C A;  3TQ4 A;  3SO2 A;  2HR6 A;  4LHR A;  3KM3 A;  3EHW A;  4DHK A;  4AOZ A;  2OKE A;  2D4N A;  1SEH A;  5ECT A;  2YZJ A;  3H6X A;  2PY4 A;  4GCY A;  3TQ3 A;  1RN8 A;  2D4M A;  3CA9 A;  2PC5 A;  2BT1 A;  2R9Q A;  4AOO A;  3ECY A;  1F7D A;  1DUC A;  2OL0 A;  1SLH A;  4B0H A;  1VYQ A;  3ZF5 A;  2HRM A;  1F7R A;  1F7N A;  1TUL A;  3I93 A;  2WE0 A;  2D4L A;  3ZEZ A;  4GV8 A;  3TRL A;  5EDD A;  1EUW A;  2WE3 A;  2HXD A;  1PKJ A;  2XCD A;  2OKD A;  3HHQ A;  2J4H A;  1Q5U X;  3T60 A;  2XX6 A;  3MBQ A;  2ZDC A;  2BAZ A;  5F9K A;  3ZF1 A;  3TPS A;  3HZA A;  3T6Y A;  2QLP A;  2J4Q A;  2QXX A;  3ARN A;  1SJN A;  1SYL A;  3ZF3 A;  1SMC A;  3TQZ A;  4XJC A;  1OGH A;  3T70 A;  3TPW A;  1MQ7 A;  3ARA A;  3MDX A;  3TS6 A;  1PKH A;  5CCO A;  1XS6 A;  2OKB A;  3P48 A;  1XS4 A;  3TPN A;  4AO5 A;  2V9X A;  1PKK A;  3TQ5 A;  2WE1 A;  1SIX A;  3TTA A;  4WRK A;  3TPY A;  3ZF0 A;  3TP1 A;  4APZ 1;  2OL1 A;  3T64 A;  3ZF2 A;  2BSY A;  2XY3 A;  1RNJ A;  2Y1T A;  1XS1 A;  3C2T A;  4GK6 A;  3F4F A;  2HXB A;  1F7Q A;  1DUP A;  3H6D A;  2HQU A;  1DUN A;  1SM8 A;  3LQW A;  1F7K A;  3GF0 A;  3ZF6 A;  2WE2 A;  1F7P A;  1F7O A;  4A6A A;  1DUT A;  3TSL A;  4OOQ A;  3TRN A;  1Q5H A;  3ZF4 A;  3C3I A;  4OOP A;  5CCT A; 
#chains in the Genus database with same CATH homology
 2XCE A;  1DUD A;  1EU5 A;  3LOJ A;  1SNF A;  2Y8C A;  3TQ4 A;  3SO2 A;  2HR6 A;  4LHR A;  3KM3 A;  3EHW A;  4DHK A;  4AOZ A;  2OKE A;  2D4N A;  1SEH A;  5ECT A;  2YZJ A;  3H6X A;  2PY4 A;  4GCY A;  3TQ3 A;  1RN8 A;  2D4M A;  3CA9 A;  2PC5 A;  2BT1 A;  2R9Q A;  4AOO A;  3ECY A;  1F7D A;  1DUC A;  2OL0 A;  1SLH A;  4B0H A;  1VYQ A;  3ZF5 A;  2HRM A;  1F7R A;  1F7N A;  3I93 A;  2WE0 A;  2D4L A;  3ZEZ A;  4GV8 A;  3TRL A;  5EDD A;  1EUW A;  2WE3 A;  2HXD A;  1PKJ A;  2XCD A;  2OKD A;  3HHQ A;  2J4H A;  1Q5U X;  3T60 A;  2XX6 A;  3MBQ A;  2ZDC A;  2BAZ A;  5F9K A;  3ZF1 A;  3TPS A;  3HZA A;  3T6Y A;  2QLP A;  2J4Q A;  2QXX A;  3ARN A;  1SJN A;  1SYL A;  3ZF3 A;  1SMC A;  3TQZ A;  4XJC A;  1OGH A;  3T70 A;  3TPW A;  1MQ7 A;  3ARA A;  3MDX A;  3TS6 A;  1PKH A;  5CCO A;  1XS6 A;  2OKB A;  3P48 A;  1XS4 A;  3TPN A;  4AO5 A;  2V9X A;  1PKK A;  3TQ5 A;  2WE1 A;  1SIX A;  3TTA A;  4WRK A;  3TPY A;  3ZF0 A;  3TP1 A;  4APZ 1;  2OL1 A;  3T64 A;  3ZF2 A;  2BSY A;  2XY3 A;  1RNJ A;  2Y1T A;  1XS1 A;  3C2T A;  4GK6 A;  3F4F A;  2HXB A;  1F7Q A;  1DUP A;  3H6D A;  2HQU A;  1DUN A;  1SM8 A;  3LQW A;  1F7K A;  3GF0 A;  3ZF6 A;  2WE2 A;  1F7P A;  1F7O A;  4A6A A;  1DUT A;  3TSL A;  4OOQ A;  3TRN A;  1Q5H A;  3ZF4 A;  3C3I A;  4OOP A;  5CCT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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