1SYLA

Crystal structure of inactive mutant dutpase complexed with substrate dutp
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
137
structure length
137
Chain Sequence
MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLNDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLINSDYQGQLMISVWNRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Catalytic Mechanism of Phosphate Ester Hydrolysis by dUTPase
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Deoxyuridine 5'-triphosphate nucleotidohydrolase
total genus 22
structure length 137
sequence length 137
ec nomenclature ec 3.6.1.23: dUTP diphosphatase.
pdb deposition date 2004-04-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00692 dUTPase dUTPase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.40.10 Mainly Beta Distorted Sandwich Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A 1sylA00
3TTAA 1RN8A 4GV8A 3ECYA 3KM3A 2BAZA 1F7NA 4GK6A 3ZF1A 1XS1A 1XS6A 3ARAA 3ZEZA 4LHRA 2D4MA 2HRMA 3HHQA 2HXBA 3TP1A 1F7OA 2D4NA 5ECTA 1SEHA 3T64A 4OOPA 1PKHA 2ZDCA 2Y8CA 3TPYA 3LOJA 3TQ3A 1SIXA 3TPSA 3C2TA 3SO2A 1PKJA 2WE3A 3F4FA 4OOQA 3ZF2A 1EUWA 1RNJA 4B0HA 2D4LA 2WE1A 1PKKA 3ARNA 3T6YA 1Q5HA 3ZF5A 3C3IA 2QLPA 1VYQA 3T70A 3TQ4A 3TPWA 1SM8A 2OKDA 1F7KA 1F7DA 2BSYA 1SLHA 3GF0A 1DUNA 3T60A 2Y1TA 1DUDA 2YZJA 3ZF0A 4AOOA 3H6DA 1DUPA 2PC5A 2J4HA 2HXDA 3P48A 3ZF6A 1DUCA 3TS6A 3CA9A 2OKEA 2XCDA 3H6XA 2XY3A 2WE0A 3MDXA 4APZ1 3TSLA 2XCEA 1SMCA 1MQ7A 4GCYA 2QXXA 3LQWA 5CCOA 2HQUA 3TQ5A 3EHWA 4XJCA 2BT1A 4DHKA 2R9QA 2XX6A 4A6AA 2J4QA 3ZF3A 1F7QA 1SJNA 4AO5A 3TRLA 3I93A 1SYLA 3TQZA 2HR6A 3ZF4A 2OL1A 1OGHA 2WE2A 5CCTA 3TPNA 4AOZA 3HZAA 1Q5UX 3MBQA 1XS4A 4WRKA 1DUTA 2OKBA 2V9XA 1F7RA 5EDDA 5F9KA 1EU5A 1F7PA 1SNFA 2PY4A 3TRNA 2OL0A
chains in the Genus database with same CATH superfamily
3TTAA 1RN8A 4GV8A 3ECYA 3KM3A 2BAZA 1F7NA 4GK6A 3ZF1A 1TULA 1XS1A 1XS6A 3ARAA 3ZEZA 4LHRA 2D4MA 2HRMA 3HHQA 2HXBA 3TP1A 1F7OA 2D4NA 5ECTA 1SEHA 3T64A 4OOPA 1PKHA 2ZDCA 2Y8CA 3TPYA 3LOJA 3TQ3A 1SIXA 3TPSA 3C2TA 3SO2A 1PKJA 2WE3A 3F4FA 4OOQA 3ZF2A 1EUWA 1RNJA 4B0HA 2D4LA 2WE1A 1PKKA 3ARNA 3T6YA 1Q5HA 3ZF5A 3C3IA 2QLPA 1VYQA 3T70A 3TQ4A 3TPWA 1SM8A 2OKDA 1F7KA 1F7DA 2BSYA 1SLHA 3GF0A 1DUNA 3T60A 2Y1TA 1DUDA 2YZJA 3ZF0A 4AOOA 3H6DA 1DUPA 2PC5A 2J4HA 2HXDA 3P48A 3ZF6A 1DUCA 3TS6A 3CA9A 2OKEA 2XCDA 3H6XA 2XY3A 2WE0A 3MDXA 4APZ1 3TSLA 2XCEA 1SMCA 1MQ7A 4GCYA 2QXXA 3LQWA 5CCOA 2HQUA 3TQ5A 3EHWA 4XJCA 2BT1A 4DHKA 2R9QA 2XX6A 4A6AA 2J4QA 3ZF3A 1F7QA 1SJNA 4AO5A 3TRLA 3I93A 1SYLA 3TQZA 2HR6A 3ZF4A 2OL1A 1OGHA 2WE2A 5CCTA 3TPNA 4AOZA 3HZAA 1Q5UX 3MBQA 1XS4A 4WRKA 1DUTA 2OKBA 2V9XA 1F7RA 5EDDA 5F9KA 1EU5A 1F7PA 1SNFA 2PY4A 3TRNA 2OL0A
chains in the Genus database with same CATH topology
3TTAA 1RN8A 4GV8A 3ECYA 3KM3A 2BAZA 1F7NA 4GK6A 3ZF1A 1XS1A 1XS6A 3ARAA 3ZEZA 4LHRA 2D4MA 2HRMA 3HHQA 2HXBA 3TP1A 1F7OA 2D4NA 5ECTA 1SEHA 3T64A 4OOPA 1PKHA 2ZDCA 2Y8CA 3TPYA 3LOJA 3TQ3A 1SIXA 3TPSA 3C2TA 3SO2A 1PKJA 2WE3A 3F4FA 4OOQA 3ZF2A 1EUWA 1RNJA 4B0HA 2D4LA 2WE1A 1PKKA 3ARNA 3T6YA 1Q5HA 3ZF5A 3C3IA 2QLPA 1VYQA 3T70A 3TQ4A 3TPWA 1SM8A 2OKDA 1F7KA 1F7DA 2BSYA 1SLHA 3GF0A 1DUNA 3T60A 2Y1TA 1DUDA 2YZJA 3ZF0A 4AOOA 3H6DA 1DUPA 2PC5A 2J4HA 2HXDA 3P48A 3ZF6A 1DUCA 3TS6A 3CA9A 2OKEA 2XCDA 3H6XA 2XY3A 2WE0A 3MDXA 4APZ1 3TSLA 2XCEA 1SMCA 1MQ7A 4GCYA 2QXXA 3LQWA 5CCOA 2HQUA 3TQ5A 3EHWA 4XJCA 2BT1A 4DHKA 2R9QA 2XX6A 4A6AA 2J4QA 3ZF3A 1F7QA 1SJNA 4AO5A 3TRLA 3I93A 1SYLA 3TQZA 2HR6A 3ZF4A 2OL1A 1OGHA 2WE2A 5CCTA 3TPNA 4AOZA 3HZAA 1Q5UX 3MBQA 1XS4A 4WRKA 1DUTA 2OKBA 2V9XA 1F7RA 5EDDA 5F9KA 1EU5A 1F7PA 1SNFA 2PY4A 3TRNA 2OL0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TTA A;  1RN8 A;  4GV8 A;  3ECY A;  3KM3 A;  2BAZ A;  1F7N A;  4GK6 A;  3ZF1 A;  1XS1 A;  1XS6 A;  3ARA A;  3ZEZ A;  4LHR A;  2D4M A;  2HRM A;  3HHQ A;  2HXB A;  3TP1 A;  1F7O A;  2D4N A;  5ECT A;  1SEH A;  3T64 A;  4OOP A;  1PKH A;  2ZDC A;  2Y8C A;  3TPY A;  3LOJ A;  3TQ3 A;  1SIX A;  3TPS A;  3C2T A;  3SO2 A;  1PKJ A;  2WE3 A;  3F4F A;  4OOQ A;  3ZF2 A;  1EUW A;  1RNJ A;  4B0H A;  2D4L A;  2WE1 A;  1PKK A;  3ARN A;  3T6Y A;  1Q5H A;  3ZF5 A;  3C3I A;  2QLP A;  1VYQ A;  3T70 A;  3TQ4 A;  3TPW A;  1SM8 A;  2OKD A;  1F7K A;  1F7D A;  2BSY A;  1SLH A;  3GF0 A;  1DUN A;  3T60 A;  2Y1T A;  1DUD A;  2YZJ A;  3ZF0 A;  4AOO A;  3H6D A;  1DUP A;  2PC5 A;  2J4H A;  2HXD A;  3P48 A;  3ZF6 A;  1DUC A;  3TS6 A;  3CA9 A;  2OKE A;  2XCD A;  3H6X A;  2XY3 A;  2WE0 A;  3MDX A;  4APZ 1;  3TSL A;  2XCE A;  1SMC A;  1MQ7 A;  4GCY A;  2QXX A;  3LQW A;  5CCO A;  2HQU A;  3TQ5 A;  3EHW A;  4XJC A;  2BT1 A;  4DHK A;  2R9Q A;  2XX6 A;  4A6A A;  2J4Q A;  3ZF3 A;  1F7Q A;  1SJN A;  4AO5 A;  3TRL A;  3I93 A;  1SYL A;  3TQZ A;  2HR6 A;  3ZF4 A;  2OL1 A;  1OGH A;  2WE2 A;  5CCT A;  3TPN A;  4AOZ A;  3HZA A;  1Q5U X;  3MBQ A;  1XS4 A;  4WRK A;  1DUT A;  2OKB A;  2V9X A;  1F7R A;  5EDD A;  5F9K A;  1EU5 A;  1F7P A;  1SNF A;  2PY4 A;  3TRN A;  2OL0 A; 
#chains in the Genus database with same CATH topology
 3TTA A;  1RN8 A;  4GV8 A;  3ECY A;  3KM3 A;  2BAZ A;  1F7N A;  4GK6 A;  3ZF1 A;  1TUL A;  1XS1 A;  1XS6 A;  3ARA A;  3ZEZ A;  4LHR A;  2D4M A;  2HRM A;  3HHQ A;  2HXB A;  3TP1 A;  1F7O A;  2D4N A;  5ECT A;  1SEH A;  3T64 A;  4OOP A;  1PKH A;  2ZDC A;  2Y8C A;  3TPY A;  3LOJ A;  3TQ3 A;  1SIX A;  3TPS A;  3C2T A;  3SO2 A;  1PKJ A;  2WE3 A;  3F4F A;  4OOQ A;  3ZF2 A;  1EUW A;  1RNJ A;  4B0H A;  2D4L A;  2WE1 A;  1PKK A;  3ARN A;  3T6Y A;  1Q5H A;  3ZF5 A;  3C3I A;  2QLP A;  1VYQ A;  3T70 A;  3TQ4 A;  3TPW A;  1SM8 A;  2OKD A;  1F7K A;  1F7D A;  2BSY A;  1SLH A;  3GF0 A;  1DUN A;  3T60 A;  2Y1T A;  1DUD A;  2YZJ A;  3ZF0 A;  4AOO A;  3H6D A;  1DUP A;  2PC5 A;  2J4H A;  2HXD A;  3P48 A;  3ZF6 A;  1DUC A;  3TS6 A;  3CA9 A;  2OKE A;  2XCD A;  3H6X A;  2XY3 A;  2WE0 A;  3MDX A;  4APZ 1;  3TSL A;  2XCE A;  1SMC A;  1MQ7 A;  4GCY A;  2QXX A;  3LQW A;  5CCO A;  2HQU A;  3TQ5 A;  3EHW A;  4XJC A;  2BT1 A;  4DHK A;  2R9Q A;  2XX6 A;  4A6A A;  2J4Q A;  3ZF3 A;  1F7Q A;  1SJN A;  4AO5 A;  3TRL A;  3I93 A;  1SYL A;  3TQZ A;  2HR6 A;  3ZF4 A;  2OL1 A;  1OGH A;  2WE2 A;  5CCT A;  3TPN A;  4AOZ A;  3HZA A;  1Q5U X;  3MBQ A;  1XS4 A;  4WRK A;  1DUT A;  2OKB A;  2V9X A;  1F7R A;  5EDD A;  5F9K A;  1EU5 A;  1F7P A;  1SNF A;  2PY4 A;  3TRN A;  2OL0 A; 
#chains in the Genus database with same CATH homology
 3TTA A;  1RN8 A;  4GV8 A;  3ECY A;  3KM3 A;  2BAZ A;  1F7N A;  4GK6 A;  3ZF1 A;  1XS1 A;  1XS6 A;  3ARA A;  3ZEZ A;  4LHR A;  2D4M A;  2HRM A;  3HHQ A;  2HXB A;  3TP1 A;  1F7O A;  2D4N A;  5ECT A;  1SEH A;  3T64 A;  4OOP A;  1PKH A;  2ZDC A;  2Y8C A;  3TPY A;  3LOJ A;  3TQ3 A;  1SIX A;  3TPS A;  3C2T A;  3SO2 A;  1PKJ A;  2WE3 A;  3F4F A;  4OOQ A;  3ZF2 A;  1EUW A;  1RNJ A;  4B0H A;  2D4L A;  2WE1 A;  1PKK A;  3ARN A;  3T6Y A;  1Q5H A;  3ZF5 A;  3C3I A;  2QLP A;  1VYQ A;  3T70 A;  3TQ4 A;  3TPW A;  1SM8 A;  2OKD A;  1F7K A;  1F7D A;  2BSY A;  1SLH A;  3GF0 A;  1DUN A;  3T60 A;  2Y1T A;  1DUD A;  2YZJ A;  3ZF0 A;  4AOO A;  3H6D A;  1DUP A;  2PC5 A;  2J4H A;  2HXD A;  3P48 A;  3ZF6 A;  1DUC A;  3TS6 A;  3CA9 A;  2OKE A;  2XCD A;  3H6X A;  2XY3 A;  2WE0 A;  3MDX A;  4APZ 1;  3TSL A;  2XCE A;  1SMC A;  1MQ7 A;  4GCY A;  2QXX A;  3LQW A;  5CCO A;  2HQU A;  3TQ5 A;  3EHW A;  4XJC A;  2BT1 A;  4DHK A;  2R9Q A;  2XX6 A;  4A6A A;  2J4Q A;  3ZF3 A;  1F7Q A;  1SJN A;  4AO5 A;  3TRL A;  3I93 A;  1SYL A;  3TQZ A;  2HR6 A;  3ZF4 A;  2OL1 A;  1OGH A;  2WE2 A;  5CCT A;  3TPN A;  4AOZ A;  3HZA A;  1Q5U X;  3MBQ A;  1XS4 A;  4WRK A;  1DUT A;  2OKB A;  2V9X A;  1F7R A;  5EDD A;  5F9K A;  1EU5 A;  1F7P A;  1SNF A;  2PY4 A;  3TRN A;  2OL0 A; 
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similar chains in the Genus database (?% sequence similarity)
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