1TQ0A

Crystal structure of the potent anticoagulant thrombin mutant w215a/e217a in free form
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
31
structure length
31
Chain Sequence
EADCGLRPLFEKKSLEDKTERELLESYIDGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket
pubmed doi rcsb
molecule tags Blood clotting
source organism Homo sapiens
molecule keywords Prothrombin
total genus 3
structure length 31
sequence length 31
chains with identical sequence C
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2004-06-16
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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