1W69 | Genus

Total Genus 113

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	113
sequence length	281
structure length	281
Chain Sequence	VEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPF

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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Viewer cachePut cache://localLOAD_/file/5cfc51d8ee96c4592156134a/pdb.gz

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Reductase
source organism	Mus musculus
publication title	Crystal Structural Studies of Changes in the Native Dinuclear Iron Center of Ribonucleotide Reductase Protein R2 from Mouse pubmed doi rcsb
molecule keywords	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 CHAIN
total genus	113
structure length	281
sequence length	281
ec nomenclature	ec 1.17.4.1: Ribonucleoside-diphosphate reductase.
pdb deposition date	2004-08-16

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00268	Ribonuc_red_sm	Ribonucleotide reductase, small chain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.620.20	Mainly Alpha	Orthogonal Bundle	Ribonucleotide Reductase, subunit A	Ribonucleotide Reductase, subunit A	1w69A00

1YFDA 3RMKA 1FZIC 1KGPA 3N3BA 3RNEA 3N3AA 5HYHA 1OQBA 1T0SB 1MXRA 4BMRA 3I5JA 3RNGA 4D8GA 2INDB 4V0JA 4BMPA 1UZRA 3GE8A 2R2FA 1BIQB 3DHGA 1MRRA 3RNAA 4BMUA 3I63A 4P1CA 1W69A 1XSMA 3PERA 4BMQA 2UW2A 1MTYB 1PFRA 5CNTE 1FZ4A 4XBWA 1XMHA 4BMTA 1FZHA 1XVGA 1FZ2C 1XU3C 2INNC 3EE4A 3Q1GA 3N20A 3Q3NA 4P1BB 5CI4A 2XZ0A 1H0NA 4M1IA 3RNCA 1XVBC 3DHIA 5EKBA 1T0SA 2ALXA 1FZ1A 1FZ9C 1RSRA 1XVFC 3Q3MA 4GAMB 1OQ9A 1JQCA 1XMGC 4N83A 1XVDA 1FZ0A 2XZ1A 1XMFC 1JK0A 1OQUA 1R65A 1XVCA 2ANIA 2RDBB 5CI3A 3RNBA 3U52C 1FZ5C 3N1XA 4BMOA 3RI7B 1FZ6A 1T0QA 3Q2AB 5CNUE 1FZ3A 1T0RB 2BQ1I 2UW1A 3DHHB 3GE3B 4M1FA 4DR0A 2O1ZA 2INPA 1PIUA 1FYZC 1XU5A 3Q14B 1FZ7C 3PF7A 3Q3OA 1ZA0A 3HF1A 2INCA 1MMOD 1XVEC 4M1HA 1SMSA 4HR4A 5HYGA 3N1ZB 4AC8A 5CI2A 1FZ8A 4D8FA 2INDA 3CHUA 1PM2A 1R2FA 2XOFA 5CNSE 4ERME 1XIKA 1FZIA 1W68A 1BIQA 1PJ1A 3N1YB 5DCRA 3OLJA 5CI1A 3RN9B 4XBVA 1T0RA 3DHHA 3CHIA 3GE3A 1MHZD 3VPMA 1RNRA 1SYYA 3VPOA 3RNFB 4HR5A 4P1BA 3I5JB 3RNGB 1PIYA 1FZ4C 3DHGB 3N38A 1XMHC 2RCCA 3RNAB 1FZHC 1XVGC 3I63B 3CHTA 2VUXA 4GAMA 1FZ2A 1XU3A 2INNA 1RIBA 4HR0A 1OQ4A 1AFRA 1KGOA 1PIZA 2JCDA 1FZ8C 1H0OA 1XVBA 3N1YA 1FZ1C 1JPRA 3Q3NB 1PIMA 2RDBA 1FZ9A 1MHYD 2J2FA 1MHZB 1XVDC 1PJ0A 1XMGA 1FZ0C 3RI7A 3RNCB 3DHIB 3RNFA 1XMFA 1XVCC 2AV8A 3CHHA 3Q3MB 3Q2AA 3N37A 3U52A 3MJOA 1FZ5A 1FZ6C 3N39A 3RMKB 1JK0B 3RNEB 3Q14A 3VPNA 3RNBB 1FZ3C 3N1XB 1MMOB 2INPC 3N1ZA 1XU5C 3GE8B 1T0QB 5CI0A 1KGNA 4DJNA 1FYZA 1FZ7A 3PM5A 1MHYB 4P1CB 1XVEA 2UW1B 1AV8A 1MTYD 1RSVA 1OQ7A 5DCOA 3Q3OB 5DCSA 4XB9A 3DHZA 5CNVE 3RN9A 2INCB 1SMQA 3N20B 1XVFA 2P1IA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1YFD A;  3RMK A;  1FZI C;  1KGP A;  3N3B A;  3RNE A;  3N3A A;  5HYH A;  1OQB A;  1T0S B;  1MXR A;  4BMR A;  3I5J A;  3RNG A;  4D8G A;  2IND B;  4V0J A;  4BMP A;  1UZR A;  3GE8 A;  2R2F A;  1BIQ B;  3DHG A;  1MRR A;  3RNA A;  4BMU A;  3I63 A;  4P1C A;  1W69 A;  1XSM A;  3PER A;  4BMQ A;  2UW2 A;  1MTY B;  1PFR A;  5CNT E;  1FZ4 A;  4XBW A;  1XMH A;  4BMT A;  1FZH A;  1XVG A;  1FZ2 C;  1XU3 C;  2INN C;  3EE4 A;  3Q1G A;  3N20 A;  3Q3N A;  4P1B B;  5CI4 A;  2XZ0 A;  1H0N A;  4M1I A;  3RNC A;  1XVB C;  3DHI A;  5EKB A;  1T0S A;  2ALX A;  1FZ1 A;  1FZ9 C;  1RSR A;  1XVF C;  3Q3M A;  4GAM B;  1OQ9 A;  1JQC A;  1XMG C;  4N83 A;  1XVD A;  1FZ0 A;  2XZ1 A;  1XMF C;  1JK0 A;  1OQU A;  1R65 A;  1XVC A;  2ANI A;  2RDB B;  5CI3 A;  3RNB A;  3U52 C;  1FZ5 C;  3N1X A;  4BMO A;  3RI7 B;  1FZ6 A;  1T0Q A;  3Q2A B;  5CNU E;  1FZ3 A;  1T0R B;  2BQ1 I;  2UW1 A;  3DHH B;  3GE3 B;  4M1F A;  4DR0 A;  2O1Z A;  2INP A;  1PIU A;  1FYZ C;  1XU5 A;  3Q14 B;  1FZ7 C;  3PF7 A;  3Q3O A;  1ZA0 A;  3HF1 A;  2INC A;  1MMO D;  1XVE C;  4M1H A;  1SMS A;  4HR4 A;  5HYG A;  3N1Z B;  4AC8 A;  5CI2 A;  1FZ8 A;  4D8F A;  2IND A;  3CHU A;  1PM2 A;  1R2F A;  2XOF A;  5CNS E;  4ERM E;  1XIK A;  1FZI A;  1W68 A;  1BIQ A;  1PJ1 A;  3N1Y B;  5DCR A;  3OLJ A;  5CI1 A;  3RN9 B;  4XBV A;  1T0R A;  3DHH A;  3CHI A;  3GE3 A;  1MHZ D;  3VPM A;  1RNR A;  1SYY A;  3VPO A;  3RNF B;  4HR5 A;  4P1B A;  3I5J B;  3RNG B;  1PIY A;  1FZ4 C;  3DHG B;  3N38 A;  1XMH C;  2RCC A;  3RNA B;  1FZH C;  1XVG C;  3I63 B;  3CHT A;  2VUX A;  4GAM A;  1FZ2 A;  1XU3 A;  2INN A;  1RIB A;  4HR0 A;  1OQ4 A;  1AFR A;  1KGO A;  1PIZ A;  2JCD A;  1FZ8 C;  1H0O A;  1XVB A;  3N1Y A;  1FZ1 C;  1JPR A;  3Q3N B;  1PIM A;  2RDB A;  1FZ9 A;  1MHY D;  2J2F A;  1MHZ B;  1XVD C;  1PJ0 A;  1XMG A;  1FZ0 C;  3RI7 A;  3RNC B;  3DHI B;  3RNF A;  1XMF A;  1XVC C;  2AV8 A;  3CHH A;  3Q3M B;  3Q2A A;  3N37 A;  3U52 A;  3MJO A;  1FZ5 A;  1FZ6 C;  3N39 A;  3RMK B;  1JK0 B;  3RNE B;  3Q14 A;  3VPN A;  3RNB B;  1FZ3 C;  3N1X B;  1MMO B;  2INP C;  3N1Z A;  1XU5 C;  3GE8 B;  1T0Q B;  5CI0 A;  1KGN A;  4DJN A;  1FYZ A;  1FZ7 A;  3PM5 A;  1MHY B;  4P1C B;  1XVE A;  2UW1 B;  1AV8 A;  1MTY D;  1RSV A;  1OQ7 A;  5DCO A;  3Q3O B;  5DCS A;  4XB9 A;  3DHZ A;  5CNV E;  3RN9 A;  2INC B;  1SMQ A;  3N20 B;  1XVF A;  2P1I A; 
#chains in the Genus database with same CATH topology
 1YFD A;  3RMK A;  1FZI C;  1KGP A;  3N3B A;  3RNE A;  3N3A A;  5HYH A;  1OQB A;  1T0S B;  1MXR A;  4BMR A;  3I5J A;  3RNG A;  4D8G A;  2IND B;  4V0J A;  4BMP A;  1UZR A;  3GE8 A;  2R2F A;  1BIQ B;  3DHG A;  1MRR A;  3RNA A;  4BMU A;  3I63 A;  4P1C A;  1W69 A;  1XSM A;  3PER A;  4BMQ A;  2UW2 A;  1MTY B;  1PFR A;  5CNT E;  1FZ4 A;  4XBW A;  1XMH A;  4BMT A;  1FZH A;  1XVG A;  1FZ2 C;  1XU3 C;  2INN C;  3EE4 A;  3Q1G A;  3N20 A;  3Q3N A;  4P1B B;  5CI4 A;  2XZ0 A;  1H0N A;  4M1I A;  3RNC A;  1XVB C;  3DHI A;  5EKB A;  1T0S A;  2ALX A;  1FZ1 A;  1FZ9 C;  1RSR A;  1XVF C;  3Q3M A;  4GAM B;  1OQ9 A;  1JQC A;  1XMG C;  4N83 A;  1XVD A;  1FZ0 A;  2XZ1 A;  1XMF C;  1JK0 A;  1OQU A;  1R65 A;  1XVC A;  2ANI A;  2RDB B;  5CI3 A;  3RNB A;  3U52 C;  1FZ5 C;  3N1X A;  4BMO A;  3RI7 B;  1FZ6 A;  1T0Q A;  3Q2A B;  5CNU E;  1FZ3 A;  1T0R B;  2BQ1 I;  2UW1 A;  3DHH B;  3GE3 B;  4M1F A;  4DR0 A;  2O1Z A;  2INP A;  1PIU A;  1FYZ C;  1XU5 A;  3Q14 B;  1FZ7 C;  3PF7 A;  3Q3O A;  1ZA0 A;  3HF1 A;  2INC A;  1MMO D;  1XVE C;  4M1H A;  1SMS A;  4HR4 A;  5HYG A;  3N1Z B;  4AC8 A;  5CI2 A;  1FZ8 A;  4D8F A;  2IND A;  3CHU A;  1PM2 A;  1R2F A;  2XOF A;  5CNS E;  4ERM E;  1XIK A;  1FZI A;  1W68 A;  1BIQ A;  1PJ1 A;  3N1Y B;  5DCR A;  3OLJ A;  5CI1 A;  3RN9 B;  4XBV A;  1T0R A;  3DHH A;  3CHI A;  3GE3 A;  1MHZ D;  3VPM A;  1RNR A;  1SYY A;  3VPO A;  3RNF B;  4HR5 A;  4P1B A;  3I5J B;  3RNG B;  1PIY A;  1FZ4 C;  3DHG B;  3N38 A;  1XMH C;  2RCC A;  3RNA B;  1FZH C;  1XVG C;  3I63 B;  3CHT A;  2VUX A;  4GAM A;  1FZ2 A;  1XU3 A;  2INN A;  1RIB A;  4HR0 A;  1OQ4 A;  1AFR A;  1KGO A;  1PIZ A;  2JCD A;  1FZ8 C;  1H0O A;  1XVB A;  3N1Y A;  1FZ1 C;  1JPR A;  3Q3N B;  1PIM A;  2RDB A;  1FZ9 A;  1MHY D;  2J2F A;  1MHZ B;  1XVD C;  1PJ0 A;  1XMG A;  1FZ0 C;  3RI7 A;  3RNC B;  3DHI B;  3RNF A;  1XMF A;  1XVC C;  2AV8 A;  3CHH A;  3Q3M B;  3Q2A A;  3N37 A;  3U52 A;  3MJO A;  1FZ5 A;  1FZ6 C;  3N39 A;  3RMK B;  1JK0 B;  3RNE B;  3Q14 A;  3VPN A;  3RNB B;  1FZ3 C;  3N1X B;  1MMO B;  2INP C;  3N1Z A;  1XU5 C;  3GE8 B;  1T0Q B;  5CI0 A;  1KGN A;  4DJN A;  1FYZ A;  1FZ7 A;  3PM5 A;  1MHY B;  4P1C B;  1XVE A;  2UW1 B;  1AV8 A;  1MTY D;  1RSV A;  1OQ7 A;  5DCO A;  3Q3O B;  5DCS A;  4XB9 A;  3DHZ A;  5CNV E;  3RN9 A;  2INC B;  1SMQ A;  3N20 B;  1XVF A;  2P1I A; 
#chains in the Genus database with same CATH homology
 1YFD A;  3RMK A;  1FZI C;  1KGP A;  3N3B A;  3RNE A;  3N3A A;  5HYH A;  1OQB A;  1T0S B;  1MXR A;  4BMR A;  3I5J A;  3RNG A;  4D8G A;  2IND B;  4V0J A;  4BMP A;  1UZR A;  3GE8 A;  2R2F A;  1BIQ B;  3DHG A;  1MRR A;  3RNA A;  4BMU A;  3I63 A;  4P1C A;  1W69 A;  1XSM A;  3PER A;  4BMQ A;  2UW2 A;  1MTY B;  1PFR A;  5CNT E;  1FZ4 A;  4XBW A;  1XMH A;  4BMT A;  1FZH A;  1XVG A;  1FZ2 C;  1XU3 C;  2INN C;  3EE4 A;  3Q1G A;  3N20 A;  3Q3N A;  4P1B B;  5CI4 A;  2XZ0 A;  1H0N A;  4M1I A;  3RNC A;  1XVB C;  3DHI A;  5EKB A;  1T0S A;  2ALX A;  1FZ1 A;  1FZ9 C;  1RSR A;  1XVF C;  3Q3M A;  4GAM B;  1OQ9 A;  1JQC A;  1XMG C;  4N83 A;  1XVD A;  1FZ0 A;  2XZ1 A;  1XMF C;  1JK0 A;  1OQU A;  1R65 A;  1XVC A;  2ANI A;  2RDB B;  5CI3 A;  3RNB A;  3U52 C;  1FZ5 C;  3N1X A;  4BMO A;  3RI7 B;  1FZ6 A;  1T0Q A;  3Q2A B;  5CNU E;  1FZ3 A;  1T0R B;  2BQ1 I;  2UW1 A;  3DHH B;  3GE3 B;  4M1F A;  4DR0 A;  2O1Z A;  2INP A;  1PIU A;  1FYZ C;  1XU5 A;  3Q14 B;  1FZ7 C;  3PF7 A;  3Q3O A;  1ZA0 A;  3HF1 A;  2INC A;  1MMO D;  1XVE C;  4M1H A;  1SMS A;  4HR4 A;  5HYG A;  3N1Z B;  4AC8 A;  5CI2 A;  1FZ8 A;  4D8F A;  2IND A;  3CHU A;  1PM2 A;  1R2F A;  2XOF A;  5CNS E;  4ERM E;  1XIK A;  1FZI A;  1W68 A;  1BIQ A;  1PJ1 A;  3N1Y B;  5DCR A;  3OLJ A;  5CI1 A;  3RN9 B;  4XBV A;  1T0R A;  3DHH A;  3CHI A;  3GE3 A;  1MHZ D;  3VPM A;  1RNR A;  1SYY A;  3VPO A;  3RNF B;  4HR5 A;  4P1B A;  3I5J B;  3RNG B;  1PIY A;  1FZ4 C;  3DHG B;  3N38 A;  1XMH C;  2RCC A;  3RNA B;  1FZH C;  1XVG C;  3I63 B;  3CHT A;  2VUX A;  4GAM A;  1FZ2 A;  1XU3 A;  2INN A;  1RIB A;  4HR0 A;  1OQ4 A;  1AFR A;  1KGO A;  1PIZ A;  2JCD A;  1FZ8 C;  1H0O A;  1XVB A;  3N1Y A;  1FZ1 C;  1JPR A;  3Q3N B;  1PIM A;  2RDB A;  1FZ9 A;  1MHY D;  2J2F A;  1MHZ B;  1XVD C;  1PJ0 A;  1XMG A;  1FZ0 C;  3RI7 A;  3RNC B;  3DHI B;  3RNF A;  1XMF A;  1XVC C;  2AV8 A;  3CHH A;  3Q3M B;  3Q2A A;  3N37 A;  3U52 A;  3MJO A;  1FZ5 A;  1FZ6 C;  3N39 A;  3RMK B;  1JK0 B;  3RNE B;  3Q14 A;  3VPN A;  3RNB B;  1FZ3 C;  3N1X B;  1MMO B;  2INP C;  3N1Z A;  1XU5 C;  3GE8 B;  1T0Q B;  5CI0 A;  1KGN A;  4DJN A;  1FYZ A;  1FZ7 A;  3PM5 A;  1MHY B;  4P1C B;  1XVE A;  2UW1 B;  1AV8 A;  1MTY D;  1RSV A;  1OQ7 A;  5DCO A;  3Q3O B;  5DCS A;  4XB9 A;  3DHZ A;  5CNV E;  3RN9 A;  2INC B;  1SMQ A;  3N20 B;  1XVF A;  2P1I A;

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similar chains in the Genus database (?% sequence similarity)

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#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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1W69A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations