2A5VA

Crystal structure of m. tuberculosis beta carbonic anhydrase, rv3588c, tetrameric form
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
210
structure length
210
Chain Sequence
HHHHHHGPNTNPVAAWKALKEGNERFVAGRPQHPSQSVDHRAGLAAGQKPTAVIFGCADSRVAAEIIFDQGLGDMFVVRTAGHVIDSAVLGSIEYAVTVLNVPLIVVLGHDSCGAVNAALAAINDGTLPGGYVRDVVERVAPSVLLGRRDGLSRVDEFEQRHVHETVAILMARSSAISERIAGGSLAIVGVTYQLDDGRAVLRDHIGNIG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Mechanics of the pH-dependent Activity of beta-Carbonic Anhydrase from Mycobacterium tuberculosis
pubmed doi rcsb
molecule tags Lyase
source organism Mycobacterium tuberculosis
molecule keywords CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRA
total genus 69
structure length 210
sequence length 210
chains with identical sequence B, C, D
ec nomenclature ec 4.2.1.1: Carbonic anhydrase.
pdb deposition date 2005-07-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00484 Pro_CA Carbonic anhydrase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1050.10 Alpha Beta 3-Layer(aba) Sandwich Beta-carbonic Anhydrase; Chain A Carbonic anhydrase 2a5vA00
4RXYA 4YF6A 3UCNA 3VQJA 3E3GA 3E31A 4WAKA 3E28A 4YF4A 2W3QA 4WAMA 1I6PA 3UCJA 3E3IA 3UCMA 3EYXA 3E1WA 1DDZA 3E2WA 3LASA 4WAJA 1YLKA 3E1VA 3E2XA 1G5CA 3MF3A 4ZNZA 5CXKA 2ESFA 2A8CA 3E2AA 3UCOA 2A8DA 1T75A 3QY1A 5BQ1A 1I6OA 5SWCA 3E3FA 3TENA 1YM3A 1EKJA 5JJ8A 4O1JA 3UCKA 3VRKA 4O1KA 3E24A 3TEOA 4YF5A 2A5VA 2W3NA
chains in the Genus database with same CATH superfamily
4RXYA 4YF6A 3UCNA 3VQJA 3E3GA 3E31A 4WAKA 3E28A 4YF4A 2W3QA 4WAMA 1I6PA 3UCJA 3E3IA 3UCMA 3EYXA 3E1WA 1DDZA 3E2WA 3LASA 4WAJA 1YLKA 3E1VA 3E2XA 1G5CA 3MF3A 4ZNZA 5CXKA 2ESFA 2A8CA 3E2AA 3UCOA 2A8DA 1T75A 3QY1A 5BQ1A 1I6OA 5SWCA 3E3FA 3TENA 1YM3A 1EKJA 5JJ8A 4O1JA 3UCKA 3VRKA 4O1KA 3E24A 3TEOA 4YF5A 2A5VA 2W3NA
chains in the Genus database with same CATH topology
4RXYA 4YF6A 3UCNA 3VQJA 3E3GA 3E31A 4WAKA 3E28A 4YF4A 2W3QA 4WAMA 1I6PA 3UCJA 3E3IA 3UCMA 3EYXA 3E1WA 1DDZA 3E2WA 3LASA 4WAJA 1YLKA 3E1VA 3E2XA 1G5CA 3MF3A 4ZNZA 5CXKA 2ESFA 2A8CA 3E2AA 3UCOA 2A8DA 1T75A 3QY1A 5BQ1A 1I6OA 5SWCA 3E3FA 3TENA 1YM3A 1EKJA 5JJ8A 4O1JA 3UCKA 3VRKA 4O1KA 3E24A 3TEOA 4YF5A 2A5VA 2W3NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RXY A;  4YF6 A;  3UCN A;  3VQJ A;  3E3G A;  3E31 A;  4WAK A;  3E28 A;  4YF4 A;  2W3Q A;  4WAM A;  1I6P A;  3UCJ A;  3E3I A;  3UCM A;  3EYX A;  3E1W A;  1DDZ A;  3E2W A;  3LAS A;  4WAJ A;  1YLK A;  3E1V A;  3E2X A;  1G5C A;  3MF3 A;  4ZNZ A;  5CXK A;  2ESF A;  2A8C A;  3E2A A;  3UCO A;  2A8D A;  1T75 A;  3QY1 A;  5BQ1 A;  1I6O A;  5SWC A;  3E3F A;  3TEN A;  1YM3 A;  1EKJ A;  5JJ8 A;  4O1J A;  3UCK A;  3VRK A;  4O1K A;  3E24 A;  3TEO A;  4YF5 A;  2A5V A;  2W3N A; 
#chains in the Genus database with same CATH topology
 4RXY A;  4YF6 A;  3UCN A;  3VQJ A;  3E3G A;  3E31 A;  4WAK A;  3E28 A;  4YF4 A;  2W3Q A;  4WAM A;  1I6P A;  3UCJ A;  3E3I A;  3UCM A;  3EYX A;  3E1W A;  1DDZ A;  3E2W A;  3LAS A;  4WAJ A;  1YLK A;  3E1V A;  3E2X A;  1G5C A;  3MF3 A;  4ZNZ A;  5CXK A;  2ESF A;  2A8C A;  3E2A A;  3UCO A;  2A8D A;  1T75 A;  3QY1 A;  5BQ1 A;  1I6O A;  5SWC A;  3E3F A;  3TEN A;  1YM3 A;  1EKJ A;  5JJ8 A;  4O1J A;  3UCK A;  3VRK A;  4O1K A;  3E24 A;  3TEO A;  4YF5 A;  2A5V A;  2W3N A; 
#chains in the Genus database with same CATH homology
 4RXY A;  4YF6 A;  3UCN A;  3VQJ A;  3E3G A;  3E31 A;  4WAK A;  3E28 A;  4YF4 A;  2W3Q A;  4WAM A;  1I6P A;  3UCJ A;  3E3I A;  3UCM A;  3EYX A;  3E1W A;  1DDZ A;  3E2W A;  3LAS A;  4WAJ A;  1YLK A;  3E1V A;  3E2X A;  1G5C A;  3MF3 A;  4ZNZ A;  5CXK A;  2ESF A;  2A8C A;  3E2A A;  3UCO A;  2A8D A;  1T75 A;  3QY1 A;  5BQ1 A;  1I6O A;  5SWC A;  3E3F A;  3TEN A;  1YM3 A;  1EKJ A;  5JJ8 A;  4O1J A;  3UCK A;  3VRK A;  4O1K A;  3E24 A;  3TEO A;  4YF5 A;  2A5V A;  2W3N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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