2AORA

Crystal structure of muth-hemimethylated dna complex
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
220
structure length
220
Chain Sequence
MIPQTLEQLLSQAQSIAGLTFGELADELHIPVPIDLKRDKGWVGMLLERALGATAGSKAEQDFSHLGVELKTLPINAEGYPLETTFVSLAPLVQNSGVKWENSHVRHKLSCVLWMPIEGSRHIPLRERHIGAPIFWKPTAEQERQLKQDWEELMDLIVLGKLDQITARIGEVMQLRPKGANSRAVTKGIGKNGEIIDTLPLGFYLRKEFTAQILNAFLET
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title MutH complexed with hemi- and unmethylated DNAs: coupling base recognition and DNA cleavage.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Haemophilus influenzae
molecule keywords 5'-D(*CP*AP*GP*GP*(6MA)P*TP*CP*CP*AP*AP*GP*CP*TP*TP*GP*GP*AP
total genus 64
structure length 220
sequence length 220
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-08-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02976 MutH DNA mismatch repair enzyme MutH
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.600.10 Alpha Beta 3-Layer(aba) Sandwich ECO RV Endonuclease; Chain A DNA mismatch repair MutH/Restriction endonuclease, type II 2aorA00
2GIEA 1EO4A 3E3YA 2B0DA 2RVEA 1RVEA 4PXGA 2GIHA 3E45A 1BUAA 1B95A 1B94A 2GIIA 1EOPA 2AUDA 3E42A 1SX5A 3E41A 1XHVA 1SUZA 1RVBA 2GIJA 2AZOA 4RVEA 5F8AA 1BSUA 1AZ0A 1STXA 2REUA 1SX8A 5HLKA 1BSSA 1RVCA 1AZ3A 1AZOA 3E40A 3E43A 3E44A 1B96A 3EBCA 1RVAA 1TW8A 2AORA 1B97A 2GIGA 1IAWA 1EO3A 1RV5A 1EV7A 2GE5A 2B0EA 1AZ4A 1XHUA 2AOQA 1TX3A 1BGBA 1EONA 1KC6A 1EOOA
chains in the Genus database with same CATH superfamily
2GIEA 1EO4A 3E3YA 2B0DA 2EZVA 1DMUA 2RVEA 1RVEA 4PXGA 2GIHA 3E45A 1BUAA 1B95A 1B94A 2GIIA 1EOPA 2AUDA 3E42A 1SX5A 3E41A 1XHVA 1SUZA 1RVBA 2GIJA 2AZOA 4RVEA 5F8AA 1BSUA 1AZ0A 1STXA 2REUA 1SX8A 5HLKA 1BSSA 2F03A 1RVCA 1AZ3A 1AZOA 3E40A 3E43A 3E44A 1B96A 3EBCA 1RVAA 1TW8A 2AORA 1B97A 2GIGA 1IAWA 1EO3A 1RV5A 1EV7A 2GE5A 2B0EA 1AZ4A 1XHUA 2AOQA 1TX3A 1BGBA 1EONA 1KC6A 1EOOA 3NDHA
chains in the Genus database with same CATH topology
2GIEA 1EO4A 3E3YA 2B0DA 2RVEA 1RVEA 4PXGA 2GIHA 3E45A 1BUAA 1B95A 1B94A 2GIIA 1EOPA 2AUDA 3E42A 1SX5A 3E41A 1XHVA 1SUZA 1RVBA 2GIJA 2AZOA 4RVEA 5F8AA 1BSUA 1AZ0A 1STXA 2REUA 1SX8A 5HLKA 1BSSA 1RVCA 1AZ3A 1AZOA 3E40A 3E43A 3E44A 1B96A 3EBCA 1RVAA 1TW8A 2AORA 1B97A 2GIGA 1IAWA 1EO3A 1RV5A 1EV7A 2GE5A 2B0EA 1AZ4A 1XHUA 2AOQA 1TX3A 1BGBA 1EONA 1KC6A 1EOOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GIE A;  1EO4 A;  3E3Y A;  2B0D A;  2RVE A;  1RVE A;  4PXG A;  2GIH A;  3E45 A;  1BUA A;  1B95 A;  1B94 A;  2GII A;  1EOP A;  2AUD A;  3E42 A;  1SX5 A;  3E41 A;  1XHV A;  1SUZ A;  1RVB A;  2GIJ A;  2AZO A;  4RVE A;  5F8A A;  1BSU A;  1AZ0 A;  1STX A;  2REU A;  1SX8 A;  5HLK A;  1BSS A;  1RVC A;  1AZ3 A;  1AZO A;  3E40 A;  3E43 A;  3E44 A;  1B96 A;  3EBC A;  1RVA A;  1TW8 A;  2AOR A;  1B97 A;  2GIG A;  1IAW A;  1EO3 A;  1RV5 A;  1EV7 A;  2GE5 A;  2B0E A;  1AZ4 A;  1XHU A;  2AOQ A;  1TX3 A;  1BGB A;  1EON A;  1KC6 A;  1EOO A; 
#chains in the Genus database with same CATH topology
 2GIE A;  1EO4 A;  3E3Y A;  2B0D A;  2EZV A;  1DMU A;  2RVE A;  1RVE A;  4PXG A;  2GIH A;  3E45 A;  1BUA A;  1B95 A;  1B94 A;  2GII A;  1EOP A;  2AUD A;  3E42 A;  1SX5 A;  3E41 A;  1XHV A;  1SUZ A;  1RVB A;  2GIJ A;  2AZO A;  4RVE A;  5F8A A;  1BSU A;  1AZ0 A;  1STX A;  2REU A;  1SX8 A;  5HLK A;  1BSS A;  2F03 A;  1RVC A;  1AZ3 A;  1AZO A;  3E40 A;  3E43 A;  3E44 A;  1B96 A;  3EBC A;  1RVA A;  1TW8 A;  2AOR A;  1B97 A;  2GIG A;  1IAW A;  1EO3 A;  1RV5 A;  1EV7 A;  2GE5 A;  2B0E A;  1AZ4 A;  1XHU A;  2AOQ A;  1TX3 A;  1BGB A;  1EON A;  1KC6 A;  1EOO A;  3NDH A; 
#chains in the Genus database with same CATH homology
 2GIE A;  1EO4 A;  3E3Y A;  2B0D A;  2RVE A;  1RVE A;  4PXG A;  2GIH A;  3E45 A;  1BUA A;  1B95 A;  1B94 A;  2GII A;  1EOP A;  2AUD A;  3E42 A;  1SX5 A;  3E41 A;  1XHV A;  1SUZ A;  1RVB A;  2GIJ A;  2AZO A;  4RVE A;  5F8A A;  1BSU A;  1AZ0 A;  1STX A;  2REU A;  1SX8 A;  5HLK A;  1BSS A;  1RVC A;  1AZ3 A;  1AZO A;  3E40 A;  3E43 A;  3E44 A;  1B96 A;  3EBC A;  1RVA A;  1TW8 A;  2AOR A;  1B97 A;  2GIG A;  1IAW A;  1EO3 A;  1RV5 A;  1EV7 A;  2GE5 A;  2B0E A;  1AZ4 A;  1XHU A;  2AOQ A;  1TX3 A;  1BGB A;  1EON A;  1KC6 A;  1EOO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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