2AZOA

Dna mismatch repair protein muth from e. coli
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
227
structure length
218
Chain Sequence
QPRPLLSPPETEEQLLAQAQQLSGYTLGELAALVGLVTPENLKRDKGWIGVLLEIWLGASAGFAALGVELKTIPVDSLGRPLETTFVCVAPLTGNSGVTWETSHVRHKLKRVLWIPVEGERSIPLAQRRVGSPLLWSPNEEEDRQLREDWEELMDMIVLGQVERITARHGEYLQIRPKAKALTEAIGARGERILTLPRGFYLKKNFTSALLARHFLIQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for MutH activation in E.coli mismatch repair and relationship of MutH to restriction endonucleases.
pubmed doi rcsb
molecule tags Endonuclease
source organism Escherichia coli
molecule keywords MUTH
total genus 51
structure length 218
sequence length 227
chains with identical sequence B
ec nomenclature
pdb deposition date 1997-11-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02976 MutH DNA mismatch repair enzyme MutH
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.600.10 Alpha Beta 3-Layer(aba) Sandwich ECO RV Endonuclease; Chain A DNA mismatch repair MutH/Restriction endonuclease, type II 2azoA00
1SX8A 1B97A 1EO4A 1B94A 5F8AA 1KC6A 1AZ3A 1XHVA 3E40A 1STXA 2AOQA 1BUAA 1TX3A 1AZOA 4RVEA 2AUDA 1BGBA 1EO3A 1RVEA 3E42A 1AZ4A 2RVEA 1EV7A 2GE5A 1XHUA 1B95A 2GIHA 1EONA 2GIGA 1RVAA 2AORA 3E3YA 4PXGA 3E41A 1B96A 2GIEA 3E43A 3E45A 1TW8A 1BSUA 1AZ0A 1EOOA 2GIJA 2AZOA 2B0EA 1RVBA 1RV5A 1SX5A 1IAWA 2GIIA 1SUZA 2B0DA 3E44A 1EOPA 5HLKA 1BSSA 3EBCA 2REUA 1RVCA
chains in the Genus database with same CATH superfamily
1SX8A 1B97A 1EO4A 1B94A 5F8AA 1KC6A 1AZ3A 1XHVA 3E40A 1STXA 2AOQA 1BUAA 1TX3A 1AZOA 4RVEA 2AUDA 1BGBA 1EO3A 2EZVA 1RVEA 3E42A 1AZ4A 2F03A 2RVEA 1EV7A 2GE5A 1XHUA 1B95A 1DMUA 2GIHA 1EONA 2GIGA 1RVAA 2AORA 3E3YA 4PXGA 3E41A 1B96A 2GIEA 3E43A 3E45A 1TW8A 1BSUA 1AZ0A 1EOOA 2GIJA 2AZOA 2B0EA 1RVBA 1RV5A 3NDHA 1SX5A 1IAWA 2GIIA 1SUZA 2B0DA 3E44A 1EOPA 5HLKA 1BSSA 3EBCA 2REUA 1RVCA
chains in the Genus database with same CATH topology
1SX8A 1B97A 1EO4A 1B94A 5F8AA 1KC6A 1AZ3A 1XHVA 3E40A 1STXA 2AOQA 1BUAA 1TX3A 1AZOA 4RVEA 2AUDA 1BGBA 1EO3A 1RVEA 3E42A 1AZ4A 2RVEA 1EV7A 2GE5A 1XHUA 1B95A 2GIHA 1EONA 2GIGA 1RVAA 2AORA 3E3YA 4PXGA 3E41A 1B96A 2GIEA 3E43A 3E45A 1TW8A 1BSUA 1AZ0A 1EOOA 2GIJA 2AZOA 2B0EA 1RVBA 1RV5A 1SX5A 1IAWA 2GIIA 1SUZA 2B0DA 3E44A 1EOPA 5HLKA 1BSSA 3EBCA 2REUA 1RVCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SX8 A;  1B97 A;  1EO4 A;  1B94 A;  5F8A A;  1KC6 A;  1AZ3 A;  1XHV A;  3E40 A;  1STX A;  2AOQ A;  1BUA A;  1TX3 A;  1AZO A;  4RVE A;  2AUD A;  1BGB A;  1EO3 A;  1RVE A;  3E42 A;  1AZ4 A;  2RVE A;  1EV7 A;  2GE5 A;  1XHU A;  1B95 A;  2GIH A;  1EON A;  2GIG A;  1RVA A;  2AOR A;  3E3Y A;  4PXG A;  3E41 A;  1B96 A;  2GIE A;  3E43 A;  3E45 A;  1TW8 A;  1BSU A;  1AZ0 A;  1EOO A;  2GIJ A;  2AZO A;  2B0E A;  1RVB A;  1RV5 A;  1SX5 A;  1IAW A;  2GII A;  1SUZ A;  2B0D A;  3E44 A;  1EOP A;  5HLK A;  1BSS A;  3EBC A;  2REU A;  1RVC A; 
#chains in the Genus database with same CATH topology
 1SX8 A;  1B97 A;  1EO4 A;  1B94 A;  5F8A A;  1KC6 A;  1AZ3 A;  1XHV A;  3E40 A;  1STX A;  2AOQ A;  1BUA A;  1TX3 A;  1AZO A;  4RVE A;  2AUD A;  1BGB A;  1EO3 A;  2EZV A;  1RVE A;  3E42 A;  1AZ4 A;  2F03 A;  2RVE A;  1EV7 A;  2GE5 A;  1XHU A;  1B95 A;  1DMU A;  2GIH A;  1EON A;  2GIG A;  1RVA A;  2AOR A;  3E3Y A;  4PXG A;  3E41 A;  1B96 A;  2GIE A;  3E43 A;  3E45 A;  1TW8 A;  1BSU A;  1AZ0 A;  1EOO A;  2GIJ A;  2AZO A;  2B0E A;  1RVB A;  1RV5 A;  3NDH A;  1SX5 A;  1IAW A;  2GII A;  1SUZ A;  2B0D A;  3E44 A;  1EOP A;  5HLK A;  1BSS A;  3EBC A;  2REU A;  1RVC A; 
#chains in the Genus database with same CATH homology
 1SX8 A;  1B97 A;  1EO4 A;  1B94 A;  5F8A A;  1KC6 A;  1AZ3 A;  1XHV A;  3E40 A;  1STX A;  2AOQ A;  1BUA A;  1TX3 A;  1AZO A;  4RVE A;  2AUD A;  1BGB A;  1EO3 A;  1RVE A;  3E42 A;  1AZ4 A;  2RVE A;  1EV7 A;  2GE5 A;  1XHU A;  1B95 A;  2GIH A;  1EON A;  2GIG A;  1RVA A;  2AOR A;  3E3Y A;  4PXG A;  3E41 A;  1B96 A;  2GIE A;  3E43 A;  3E45 A;  1TW8 A;  1BSU A;  1AZ0 A;  1EOO A;  2GIJ A;  2AZO A;  2B0E A;  1RVB A;  1RV5 A;  1SX5 A;  1IAW A;  2GII A;  1SUZ A;  2B0D A;  3E44 A;  1EOP A;  5HLK A;  1BSS A;  3EBC A;  2REU A;  1RVC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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