2ERHB

Crystal structure of the e7_g/im7_g complex; a designed interface between the colicin e7 dnase and the im7 immunity protein
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
127
structure length
127
Chain Sequence
RNKPGKATGKGKPVNNKWLNNAGKDLGSPVPDRIANKLRDKEFKSFDDFRKKFWEEVSKDPELSKQFSRTQNDRMKVGRAPQTRTQDVSGKRQSFELHHEKPISQNGGVYDMDNISVVTPKRHIDIH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Computational Design of a New Hydrogen Bond Network and at Least a 300-fold Specificity Switch at a Protein-Protein Interface.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Escherichia coli
molecule keywords Colicin E7 immunity protein
total genus 36
structure length 127
sequence length 127
ec nomenclature ec 3.1.-.-:
pdb deposition date 2005-10-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.540.10 Alpha Beta Alpha-Beta Complex Colicin E7 immunity protein; Chain B, fragment: Endonuclease domain Colicin/pyocin, DNase domain 2erhB00
2K5XB 4QKOB 2JAZB 1UJZB 2IVHA 2GZFB 3U43B 1ZNSA 4UHQA 3FBDA 2GZIB 1V14A 2GZGB 1BXIB 2VLOB 1MZ8B 3GJNB 1V13A 3GKLA 1FSJB 1EMVB 2GZEB 2VLPB 1ZNVB 2ERHB 1PT3A 2VLQB 2WPTB 3ZFKA 1V15A 2GYKB 2JBGB 2JB0B 2VLNB 7CEIB 1M08A 2GZJB 4UHPA 1FR2B
chains in the Genus database with same CATH superfamily
2K5XB 4QKOB 2JAZB 1UJZB 2IVHA 2GZFB 3U43B 1ZNSA 4UHQA 3FBDA 2GZIB 1V14A 2GZGB 1BXIB 2VLOB 1MZ8B 3GJNB 1V13A 3GKLA 1FSJB 1EMVB 2GZEB 2VLPB 1ZNVB 2ERHB 1PT3A 2VLQB 2WPTB 3ZFKA 1V15A 2GYKB 2JBGB 2JB0B 2VLNB 7CEIB 1M08A 2GZJB 4UHPA 1FR2B
chains in the Genus database with same CATH topology
2K5XB 4QKOB 2JAZB 1UJZB 2IVHA 2GZFB 3U43B 1ZNSA 4UHQA 3FBDA 2GZIB 1V14A 2GZGB 1BXIB 2VLOB 1MZ8B 3GJNB 1V13A 3GKLA 1FSJB 1EMVB 2GZEB 2VLPB 1ZNVB 2ERHB 1PT3A 2VLQB 2WPTB 3ZFKA 1V15A 2GYKB 2JBGB 2JB0B 2VLNB 7CEIB 1M08A 2GZJB 4UHPA 1FR2B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2K5X B;  4QKO B;  2JAZ B;  1UJZ B;  2IVH A;  2GZF B;  3U43 B;  1ZNS A;  4UHQ A;  3FBD A;  2GZI B;  1V14 A;  2GZG B;  1BXI B;  2VLO B;  1MZ8 B;  3GJN B;  1V13 A;  3GKL A;  1FSJ B;  1EMV B;  2GZE B;  2VLP B;  1ZNV B;  2ERH B;  1PT3 A;  2VLQ B;  2WPT B;  3ZFK A;  1V15 A;  2GYK B;  2JBG B;  2JB0 B;  2VLN B;  7CEI B;  1M08 A;  2GZJ B;  4UHP A;  1FR2 B; 
#chains in the Genus database with same CATH topology
 2K5X B;  4QKO B;  2JAZ B;  1UJZ B;  2IVH A;  2GZF B;  3U43 B;  1ZNS A;  4UHQ A;  3FBD A;  2GZI B;  1V14 A;  2GZG B;  1BXI B;  2VLO B;  1MZ8 B;  3GJN B;  1V13 A;  3GKL A;  1FSJ B;  1EMV B;  2GZE B;  2VLP B;  1ZNV B;  2ERH B;  1PT3 A;  2VLQ B;  2WPT B;  3ZFK A;  1V15 A;  2GYK B;  2JBG B;  2JB0 B;  2VLN B;  7CEI B;  1M08 A;  2GZJ B;  4UHP A;  1FR2 B; 
#chains in the Genus database with same CATH homology
 2K5X B;  4QKO B;  2JAZ B;  1UJZ B;  2IVH A;  2GZF B;  3U43 B;  1ZNS A;  4UHQ A;  3FBD A;  2GZI B;  1V14 A;  2GZG B;  1BXI B;  2VLO B;  1MZ8 B;  3GJN B;  1V13 A;  3GKL A;  1FSJ B;  1EMV B;  2GZE B;  2VLP B;  1ZNV B;  2ERH B;  1PT3 A;  2VLQ B;  2WPT B;  3ZFK A;  1V15 A;  2GYK B;  2JBG B;  2JB0 B;  2VLN B;  7CEI B;  1M08 A;  2GZJ B;  4UHP A;  1FR2 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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