2EW5A

Structure of helicobacter pylori peptide deformylase in complex with inhibitor
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
166
structure length
166
Chain Sequence
ALLEIIHYPSKILRTISKEVVSFDAKLHQQLDDMYETMIASEGIGLAAIQVGLPLRMLIINLPQEDGVQHKEDCLEIINPKFIETGGSMMYKEGCLSVPGFYEEVERFEKVKIEYQNRFAEVKVLEASELLAVAIQHEIDHLNGVLFVDKLSILKRKKFEKELKEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: reverse docking, enzymatic assay, and X-ray crystallography validation
pubmed doi rcsb
molecule tags Hydrolase
source organism Helicobacter pylori
molecule keywords peptide deformylase
total genus 50
structure length 166
sequence length 166
ec nomenclature ec 3.5.1.88: Peptide deformylase.
pdb deposition date 2005-11-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01327 Pep_deformylase Polypeptide deformylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.45.10 Alpha Beta Alpha-Beta Complex Peptide Deformylase Peptide deformylase 2ew5A00
5JEXA 3FWXA 5CY7A 1BSZA 2AIAA 1LRUA 3SW8P 4DR8A 4WXLA 1BS4A 2AIEP 2EW7A 1SV2A 3M6PA 3M6RA 1ICJA 5CXJA 1BSKA 5JF8A 3M6QA 1ZY0A 2OKLA 1V3YA 3U7MA 3PN5A 5CWXA 4EOXP 3U7KA 3STRP 1VEVA 3SVJP 1ZY1A 2AI8A 3G6NA 4AZ4A 3PN3A 5JF0A 2EW6A 5CVQA 1RQCA 4WXKA 1BS5A 5CWYA 4AL2A 1BSJA 3U04A 3QU1A 2W3UA 1WS0A 1SZZA 1XEMA 4JE6A 1BS8A 1JYMA 5CPDA 2DEFA 5JF3A 5JF4A 2OS3A 5JF7A 2AI9A 3E3UA 1LRYA 3CMDA 2AI7A 1LQWA 5JF6A 1G27A 3O3JA 4DR9A 1WS1A 1XENA 5J46A 5JF2A 3U7NA 1S17A 5T8ZA 5JEYA 1LM4A 2W3TA 5I2BA 3CPMA 3L87A 5CX0A 1DFFA 3PN4A 1IX1A 1Y6HA 1Q1YA 3UWBA 1LMEA 5CVPA 1BS6A 1XEOA 1ZXZA 4E9AA 5JF1A 3G5KA 1LM6A 4JE7A 5KOBA 1N5NA 1BS7A 5CY8A 4AL3A 1DEFA 2EW5A 5JF5A 4NT8A 5CVKA 2KMNA 1LQYA 1VEYA 1G2AA 2OS0A 5E5DA 4E9BA 1VEZA 3K6LA 3U7LA 5HGWA 3UWAA 5CP0A 3OCAA 3PN6A 1RL4A 1LMHA 5JEZA 3PN2A 3G5PA 2OS1A 3M6OA 4JE8A
chains in the Genus database with same CATH superfamily
5JEXA 3FWXA 5CY7A 1BSZA 2AIAA 1LRUA 3SW8P 4DR8A 4WXLA 1BS4A 2AIEP 2EW7A 1SV2A 3M6PA 3M6RA 1ICJA 5CXJA 1BSKA 5JF8A 3M6QA 1ZY0A 2OKLA 1V3YA 3U7MA 3PN5A 5CWXA 4EOXP 3U7KA 3STRP 1VEVA 3SVJP 1ZY1A 2AI8A 3G6NA 4AZ4A 3PN3A 5JF0A 2EW6A 5CVQA 1RQCA 4WXKA 1BS5A 5CWYA 4AL2A 1BSJA 3U04A 3QU1A 2W3UA 1WS0A 1SZZA 1XEMA 4JE6A 1BS8A 1JYMA 5CPDA 2DEFA 5JF3A 5JF4A 2OS3A 5JF7A 2AI9A 3E3UA 1LRYA 3CMDA 2AI7A 1LQWA 5JF6A 1G27A 3O3JA 4DR9A 1WS1A 1XENA 5J46A 5JF2A 3U7NA 1S17A 5T8ZA 5JEYA 1LM4A 2W3TA 5I2BA 3CPMA 3L87A 5CX0A 1DFFA 3PN4A 1IX1A 1Y6HA 1Q1YA 3UWBA 1LMEA 5CVPA 1BS6A 1XEOA 1ZXZA 4E9AA 5JF1A 3G5KA 1LM6A 4JE7A 5KOBA 1N5NA 1BS7A 5CY8A 4AL3A 1DEFA 2EW5A 5JF5A 4NT8A 5CVKA 2KMNA 1LQYA 1VEYA 1G2AA 2OS0A 5E5DA 4E9BA 1VEZA 3K6LA 3U7LA 5HGWA 3UWAA 5CP0A 3OCAA 3PN6A 1RL4A 1LMHA 5JEZA 3PN2A 3G5PA 2OS1A 3M6OA 4JE8A
chains in the Genus database with same CATH topology
5JEXA 3FWXA 5CY7A 1BSZA 2AIAA 1LRUA 3SW8P 4DR8A 4WXLA 1BS4A 2AIEP 2EW7A 1SV2A 3M6PA 3M6RA 1ICJA 5CXJA 1BSKA 5JF8A 3M6QA 1ZY0A 2OKLA 1V3YA 3U7MA 3PN5A 5CWXA 4EOXP 3U7KA 3STRP 1VEVA 3SVJP 1ZY1A 2AI8A 3G6NA 4AZ4A 3PN3A 5JF0A 2EW6A 5CVQA 1RQCA 4WXKA 1BS5A 5CWYA 4AL2A 1BSJA 3U04A 3QU1A 2W3UA 1WS0A 1SZZA 1XEMA 4JE6A 1BS8A 1JYMA 5CPDA 2DEFA 5JF3A 5JF4A 2OS3A 5JF7A 2AI9A 3E3UA 1LRYA 3CMDA 2AI7A 1LQWA 5JF6A 1G27A 3O3JA 4DR9A 1WS1A 1XENA 5J46A 5JF2A 3U7NA 1S17A 5T8ZA 5JEYA 1LM4A 2W3TA 5I2BA 3CPMA 3L87A 5CX0A 1DFFA 3PN4A 1IX1A 1Y6HA 1Q1YA 3UWBA 1LMEA 5CVPA 1BS6A 1XEOA 1ZXZA 4E9AA 5JF1A 3G5KA 1LM6A 4JE7A 5KOBA 1N5NA 1BS7A 5CY8A 4AL3A 1DEFA 2EW5A 5JF5A 4NT8A 5CVKA 2KMNA 1LQYA 1VEYA 1G2AA 2OS0A 5E5DA 4E9BA 1VEZA 3K6LA 3U7LA 5HGWA 3UWAA 5CP0A 3OCAA 3PN6A 1RL4A 1LMHA 5JEZA 3PN2A 3G5PA 2OS1A 3M6OA 4JE8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JEX A;  3FWX A;  5CY7 A;  1BSZ A;  2AIA A;  1LRU A;  3SW8 P;  4DR8 A;  4WXL A;  1BS4 A;  2AIE P;  2EW7 A;  1SV2 A;  3M6P A;  3M6R A;  1ICJ A;  5CXJ A;  1BSK A;  5JF8 A;  3M6Q A;  1ZY0 A;  2OKL A;  1V3Y A;  3U7M A;  3PN5 A;  5CWX A;  4EOX P;  3U7K A;  3STR P;  1VEV A;  3SVJ P;  1ZY1 A;  2AI8 A;  3G6N A;  4AZ4 A;  3PN3 A;  5JF0 A;  2EW6 A;  5CVQ A;  1RQC A;  4WXK A;  1BS5 A;  5CWY A;  4AL2 A;  1BSJ A;  3U04 A;  3QU1 A;  2W3U A;  1WS0 A;  1SZZ A;  1XEM A;  4JE6 A;  1BS8 A;  1JYM A;  5CPD A;  2DEF A;  5JF3 A;  5JF4 A;  2OS3 A;  5JF7 A;  2AI9 A;  3E3U A;  1LRY A;  3CMD A;  2AI7 A;  1LQW A;  5JF6 A;  1G27 A;  3O3J A;  4DR9 A;  1WS1 A;  1XEN A;  5J46 A;  5JF2 A;  3U7N A;  1S17 A;  5T8Z A;  5JEY A;  1LM4 A;  2W3T A;  5I2B A;  3CPM A;  3L87 A;  5CX0 A;  1DFF A;  3PN4 A;  1IX1 A;  1Y6H A;  1Q1Y A;  3UWB A;  1LME A;  5CVP A;  1BS6 A;  1XEO A;  1ZXZ A;  4E9A A;  5JF1 A;  3G5K A;  1LM6 A;  4JE7 A;  5KOB A;  1N5N A;  1BS7 A;  5CY8 A;  4AL3 A;  1DEF A;  2EW5 A;  5JF5 A;  4NT8 A;  5CVK A;  2KMN A;  1LQY A;  1VEY A;  1G2A A;  2OS0 A;  5E5D A;  4E9B A;  1VEZ A;  3K6L A;  3U7L A;  5HGW A;  3UWA A;  5CP0 A;  3OCA A;  3PN6 A;  1RL4 A;  1LMH A;  5JEZ A;  3PN2 A;  3G5P A;  2OS1 A;  3M6O A;  4JE8 A; 
#chains in the Genus database with same CATH topology
 5JEX A;  3FWX A;  5CY7 A;  1BSZ A;  2AIA A;  1LRU A;  3SW8 P;  4DR8 A;  4WXL A;  1BS4 A;  2AIE P;  2EW7 A;  1SV2 A;  3M6P A;  3M6R A;  1ICJ A;  5CXJ A;  1BSK A;  5JF8 A;  3M6Q A;  1ZY0 A;  2OKL A;  1V3Y A;  3U7M A;  3PN5 A;  5CWX A;  4EOX P;  3U7K A;  3STR P;  1VEV A;  3SVJ P;  1ZY1 A;  2AI8 A;  3G6N A;  4AZ4 A;  3PN3 A;  5JF0 A;  2EW6 A;  5CVQ A;  1RQC A;  4WXK A;  1BS5 A;  5CWY A;  4AL2 A;  1BSJ A;  3U04 A;  3QU1 A;  2W3U A;  1WS0 A;  1SZZ A;  1XEM A;  4JE6 A;  1BS8 A;  1JYM A;  5CPD A;  2DEF A;  5JF3 A;  5JF4 A;  2OS3 A;  5JF7 A;  2AI9 A;  3E3U A;  1LRY A;  3CMD A;  2AI7 A;  1LQW A;  5JF6 A;  1G27 A;  3O3J A;  4DR9 A;  1WS1 A;  1XEN A;  5J46 A;  5JF2 A;  3U7N A;  1S17 A;  5T8Z A;  5JEY A;  1LM4 A;  2W3T A;  5I2B A;  3CPM A;  3L87 A;  5CX0 A;  1DFF A;  3PN4 A;  1IX1 A;  1Y6H A;  1Q1Y A;  3UWB A;  1LME A;  5CVP A;  1BS6 A;  1XEO A;  1ZXZ A;  4E9A A;  5JF1 A;  3G5K A;  1LM6 A;  4JE7 A;  5KOB A;  1N5N A;  1BS7 A;  5CY8 A;  4AL3 A;  1DEF A;  2EW5 A;  5JF5 A;  4NT8 A;  5CVK A;  2KMN A;  1LQY A;  1VEY A;  1G2A A;  2OS0 A;  5E5D A;  4E9B A;  1VEZ A;  3K6L A;  3U7L A;  5HGW A;  3UWA A;  5CP0 A;  3OCA A;  3PN6 A;  1RL4 A;  1LMH A;  5JEZ A;  3PN2 A;  3G5P A;  2OS1 A;  3M6O A;  4JE8 A; 
#chains in the Genus database with same CATH homology
 5JEX A;  3FWX A;  5CY7 A;  1BSZ A;  2AIA A;  1LRU A;  3SW8 P;  4DR8 A;  4WXL A;  1BS4 A;  2AIE P;  2EW7 A;  1SV2 A;  3M6P A;  3M6R A;  1ICJ A;  5CXJ A;  1BSK A;  5JF8 A;  3M6Q A;  1ZY0 A;  2OKL A;  1V3Y A;  3U7M A;  3PN5 A;  5CWX A;  4EOX P;  3U7K A;  3STR P;  1VEV A;  3SVJ P;  1ZY1 A;  2AI8 A;  3G6N A;  4AZ4 A;  3PN3 A;  5JF0 A;  2EW6 A;  5CVQ A;  1RQC A;  4WXK A;  1BS5 A;  5CWY A;  4AL2 A;  1BSJ A;  3U04 A;  3QU1 A;  2W3U A;  1WS0 A;  1SZZ A;  1XEM A;  4JE6 A;  1BS8 A;  1JYM A;  5CPD A;  2DEF A;  5JF3 A;  5JF4 A;  2OS3 A;  5JF7 A;  2AI9 A;  3E3U A;  1LRY A;  3CMD A;  2AI7 A;  1LQW A;  5JF6 A;  1G27 A;  3O3J A;  4DR9 A;  1WS1 A;  1XEN A;  5J46 A;  5JF2 A;  3U7N A;  1S17 A;  5T8Z A;  5JEY A;  1LM4 A;  2W3T A;  5I2B A;  3CPM A;  3L87 A;  5CX0 A;  1DFF A;  3PN4 A;  1IX1 A;  1Y6H A;  1Q1Y A;  3UWB A;  1LME A;  5CVP A;  1BS6 A;  1XEO A;  1ZXZ A;  4E9A A;  5JF1 A;  3G5K A;  1LM6 A;  4JE7 A;  5KOB A;  1N5N A;  1BS7 A;  5CY8 A;  4AL3 A;  1DEF A;  2EW5 A;  5JF5 A;  4NT8 A;  5CVK A;  2KMN A;  1LQY A;  1VEY A;  1G2A A;  2OS0 A;  5E5D A;  4E9B A;  1VEZ A;  3K6L A;  3U7L A;  5HGW A;  3UWA A;  5CP0 A;  3OCA A;  3PN6 A;  1RL4 A;  1LMH A;  5JEZ A;  3PN2 A;  3G5P A;  2OS1 A;  3M6O A;  4JE8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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