2I60G

Crystal structure of [phe23]m47, a scorpion-toxin mimic of cd4, in complex with hiv-1 yu2 gp120 envelope glycoprotein and anti-hiv-1 antibody 17b
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
309
structure length
301
Chain Sequence
EVKLENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVGAGSCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNDKKFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEIVIRSENFTNNAKTIIVQLNESVVINCTGAGHCNLSKTQWENTLEQIAIKLKEQFGNNKTIIFNPSSGGDPEIVTHSFNCGGEFFYCNSTQLFTWNDRNITLPCRIKQIINMWQEVGKAMYAPPIRGQIRCSSNITGLLLTRDGGKDTNGTEIFRPGGGDMRDNWRSELYKYKVVKIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Combinatorial optimization of a CD4-mimetic miniprotein and cocrystal structures with HIV-1 gp120 envelope glycoprotein.
pubmed doi rcsb
molecule tags Viral protein/immune system
source organism Human immunodeficiency virus 1
molecule keywords EXTERIOR MEMBRANE GLYCOPROTEIN(GP120)
total genus 81
structure length 301
sequence length 309
chains with identical sequence P
ec nomenclature
pdb deposition date 2006-08-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.40.20 Mainly Beta Beta Complex HIV Envelope Protein Gp120; Chain G Human immunodeficiency virus 1, Gp160, envelope glycoprotein 2i60G00
4LSRG 4DKRA 4RFNA 3U7YG 4JB9G 2NY1A 5F4RA 3TGQA 4YDLA 4I54A 4DKOA 3NGBA 4OLWG 2NXYA 1G9MG 4DVVA 4JZWA 5F4PA 3RJQA 4S1QG 4LSPG 2NY0A 3LQAG 5TE7G 4LSUG 4XNYG 4RWYA 4DKQA 4YDKG 4XVTG 1RZJG 4LSVG 4DVTA 3IDYA 5FA2A 5T33G 2NY2A 4DKPA 5KJRG 2I60G 4OLYG 4XMPG 4LSSG 3JWDA 5CAYG 5F4LA 4JM2E 5F9OG 5F96G 3TGTA 5TE4G 4JDTG 4YE4G 4YFLE 2NY7G 4RX4E 3JWOA 3TGRA 2NY3A 4OM1G 5TE6G 4S1RG 4P9HG 4OLUG 4KA2A 1G9NG 4JPWG 4LSQG 4JKPG 1GC1G 3IDXG 4OM0G 2I5YG 4DVSA 4JPVG 4YDJG 4DKUA 4H8WG 4OLZG 1YYMG 3HI1G 4OLXG 2NY4A 5FECC 2QADA 5F4UA 1YYLG 3FUSA 4OLVG 4DVRG 4LAJA 3TGSA 4JZZA 4J6RG 3SE8G 4K0AA 2NXZA 4S1SG 4I53A 4LSTG 2NY5G 5I9QA 4RZ8A 4XVSG 5CD5A 2BF1A 3SE9G 5F9WA 4RFOG 4XNZA 5IGXG 4DVWA 3TIHA 4DKVA 4R4NA 2B4CG 4R4FA 4DVXA 4R2GA 2NY6A 4YDIG 1RZKG
chains in the Genus database with same CATH superfamily
4LSRG 4DKRA 4RFNA 3U7YG 4JB9G 2NY1A 5F4RA 3TGQA 4YDLA 4I54A 4DKOA 3NGBA 4OLWG 2NXYA 1G9MG 4DVVA 4JZWA 5F4PA 3RJQA 4S1QG 4LSPG 2NY0A 3LQAG 5TE7G 4LSUG 4XNYG 4RWYA 4DKQA 4YDKG 4XVTG 1RZJG 4LSVG 4DVTA 3IDYA 5FA2A 5T33G 2NY2A 4DKPA 5KJRG 2I60G 4OLYG 4XMPG 4LSSG 3JWDA 5CAYG 5F4LA 4JM2E 5F9OG 5F96G 3TGTA 5TE4G 4JDTG 4YE4G 4YFLE 2NY7G 4RX4E 3JWOA 3TGRA 2NY3A 4OM1G 5TE6G 4S1RG 4P9HG 4OLUG 4KA2A 1G9NG 4JPWG 4LSQG 4JKPG 1GC1G 3IDXG 4OM0G 2I5YG 4DVSA 4JPVG 4YDJG 4DKUA 4H8WG 4OLZG 1YYMG 3HI1G 4OLXG 2NY4A 5FECC 2QADA 5F4UA 1YYLG 3FUSA 4OLVG 4DVRG 4LAJA 3TGSA 4JZZA 4J6RG 3SE8G 4K0AA 2NXZA 4S1SG 4I53A 4LSTG 2NY5G 5I9QA 4RZ8A 4XVSG 5CD5A 2BF1A 3SE9G 5F9WA 4RFOG 4XNZA 5IGXG 4DVWA 3TIHA 4DKVA 4R4NA 2B4CG 4R4FA 4DVXA 4R2GA 2NY6A 4YDIG 1RZKG
chains in the Genus database with same CATH topology
4LSRG 4DKRA 4RFNA 3U7YG 4JB9G 2NY1A 5F4RA 3TGQA 4YDLA 4I54A 4DKOA 3NGBA 4OLWG 2NXYA 1G9MG 4DVVA 4JZWA 5F4PA 3RJQA 4S1QG 4LSPG 2NY0A 3LQAG 5TE7G 4LSUG 4XNYG 4RWYA 4DKQA 4YDKG 4XVTG 1RZJG 4LSVG 4DVTA 3IDYA 5FA2A 5T33G 2NY2A 4DKPA 5KJRG 2I60G 4OLYG 4XMPG 4LSSG 3JWDA 5CAYG 5F4LA 4JM2E 5F9OG 5F96G 3TGTA 5TE4G 4JDTG 4YE4G 4YFLE 2NY7G 4RX4E 3JWOA 3TGRA 2NY3A 4OM1G 5TE6G 4S1RG 4P9HG 4OLUG 4KA2A 1G9NG 4JPWG 4LSQG 4JKPG 1GC1G 3IDXG 4OM0G 2I5YG 4DVSA 4JPVG 4YDJG 4DKUA 4H8WG 4OLZG 1YYMG 3HI1G 4OLXG 2NY4A 5FECC 2QADA 5F4UA 1YYLG 3FUSA 4OLVG 4DVRG 4LAJA 3TGSA 4JZZA 4J6RG 3SE8G 4K0AA 2NXZA 4S1SG 4I53A 4LSTG 2NY5G 5I9QA 4RZ8A 4XVSG 5CD5A 2BF1A 3SE9G 5F9WA 4RFOG 4XNZA 5IGXG 4DVWA 3TIHA 4DKVA 4R4NA 2B4CG 4R4FA 4DVXA 4R2GA 2NY6A 4YDIG 1RZKG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LSR G;  4DKR A;  4RFN A;  3U7Y G;  4JB9 G;  2NY1 A;  5F4R A;  3TGQ A;  4YDL A;  4I54 A;  4DKO A;  3NGB A;  4OLW G;  2NXY A;  1G9M G;  4DVV A;  4JZW A;  5F4P A;  3RJQ A;  4S1Q G;  4LSP G;  2NY0 A;  3LQA G;  5TE7 G;  4LSU G;  4XNY G;  4RWY A;  4DKQ A;  4YDK G;  4XVT G;  1RZJ G;  4LSV G;  4DVT A;  3IDY A;  5FA2 A;  5T33 G;  2NY2 A;  4DKP A;  5KJR G;  2I60 G;  4OLY G;  4XMP G;  4LSS G;  3JWD A;  5CAY G;  5F4L A;  4JM2 E;  5F9O G;  5F96 G;  3TGT A;  5TE4 G;  4JDT G;  4YE4 G;  4YFL E;  2NY7 G;  4RX4 E;  3JWO A;  3TGR A;  2NY3 A;  4OM1 G;  5TE6 G;  4S1R G;  4P9H G;  4OLU G;  4KA2 A;  1G9N G;  4JPW G;  4LSQ G;  4JKP G;  1GC1 G;  3IDX G;  4OM0 G;  2I5Y G;  4DVS A;  4JPV G;  4YDJ G;  4DKU A;  4H8W G;  4OLZ G;  1YYM G;  3HI1 G;  4OLX G;  2NY4 A;  5FEC C;  2QAD A;  5F4U A;  1YYL G;  3FUS A;  4OLV G;  4DVR G;  4LAJ A;  3TGS A;  4JZZ A;  4J6R G;  3SE8 G;  4K0A A;  2NXZ A;  4S1S G;  4I53 A;  4LST G;  2NY5 G;  5I9Q A;  4RZ8 A;  4XVS G;  5CD5 A;  2BF1 A;  3SE9 G;  5F9W A;  4RFO G;  4XNZ A;  5IGX G;  4DVW A;  3TIH A;  4DKV A;  4R4N A;  2B4C G;  4R4F A;  4DVX A;  4R2G A;  2NY6 A;  4YDI G;  1RZK G; 
#chains in the Genus database with same CATH topology
 4LSR G;  4DKR A;  4RFN A;  3U7Y G;  4JB9 G;  2NY1 A;  5F4R A;  3TGQ A;  4YDL A;  4I54 A;  4DKO A;  3NGB A;  4OLW G;  2NXY A;  1G9M G;  4DVV A;  4JZW A;  5F4P A;  3RJQ A;  4S1Q G;  4LSP G;  2NY0 A;  3LQA G;  5TE7 G;  4LSU G;  4XNY G;  4RWY A;  4DKQ A;  4YDK G;  4XVT G;  1RZJ G;  4LSV G;  4DVT A;  3IDY A;  5FA2 A;  5T33 G;  2NY2 A;  4DKP A;  5KJR G;  2I60 G;  4OLY G;  4XMP G;  4LSS G;  3JWD A;  5CAY G;  5F4L A;  4JM2 E;  5F9O G;  5F96 G;  3TGT A;  5TE4 G;  4JDT G;  4YE4 G;  4YFL E;  2NY7 G;  4RX4 E;  3JWO A;  3TGR A;  2NY3 A;  4OM1 G;  5TE6 G;  4S1R G;  4P9H G;  4OLU G;  4KA2 A;  1G9N G;  4JPW G;  4LSQ G;  4JKP G;  1GC1 G;  3IDX G;  4OM0 G;  2I5Y G;  4DVS A;  4JPV G;  4YDJ G;  4DKU A;  4H8W G;  4OLZ G;  1YYM G;  3HI1 G;  4OLX G;  2NY4 A;  5FEC C;  2QAD A;  5F4U A;  1YYL G;  3FUS A;  4OLV G;  4DVR G;  4LAJ A;  3TGS A;  4JZZ A;  4J6R G;  3SE8 G;  4K0A A;  2NXZ A;  4S1S G;  4I53 A;  4LST G;  2NY5 G;  5I9Q A;  4RZ8 A;  4XVS G;  5CD5 A;  2BF1 A;  3SE9 G;  5F9W A;  4RFO G;  4XNZ A;  5IGX G;  4DVW A;  3TIH A;  4DKV A;  4R4N A;  2B4C G;  4R4F A;  4DVX A;  4R2G A;  2NY6 A;  4YDI G;  1RZK G; 
#chains in the Genus database with same CATH homology
 4LSR G;  4DKR A;  4RFN A;  3U7Y G;  4JB9 G;  2NY1 A;  5F4R A;  3TGQ A;  4YDL A;  4I54 A;  4DKO A;  3NGB A;  4OLW G;  2NXY A;  1G9M G;  4DVV A;  4JZW A;  5F4P A;  3RJQ A;  4S1Q G;  4LSP G;  2NY0 A;  3LQA G;  5TE7 G;  4LSU G;  4XNY G;  4RWY A;  4DKQ A;  4YDK G;  4XVT G;  1RZJ G;  4LSV G;  4DVT A;  3IDY A;  5FA2 A;  5T33 G;  2NY2 A;  4DKP A;  5KJR G;  2I60 G;  4OLY G;  4XMP G;  4LSS G;  3JWD A;  5CAY G;  5F4L A;  4JM2 E;  5F9O G;  5F96 G;  3TGT A;  5TE4 G;  4JDT G;  4YE4 G;  4YFL E;  2NY7 G;  4RX4 E;  3JWO A;  3TGR A;  2NY3 A;  4OM1 G;  5TE6 G;  4S1R G;  4P9H G;  4OLU G;  4KA2 A;  1G9N G;  4JPW G;  4LSQ G;  4JKP G;  1GC1 G;  3IDX G;  4OM0 G;  2I5Y G;  4DVS A;  4JPV G;  4YDJ G;  4DKU A;  4H8W G;  4OLZ G;  1YYM G;  3HI1 G;  4OLX G;  2NY4 A;  5FEC C;  2QAD A;  5F4U A;  1YYL G;  3FUS A;  4OLV G;  4DVR G;  4LAJ A;  3TGS A;  4JZZ A;  4J6R G;  3SE8 G;  4K0A A;  2NXZ A;  4S1S G;  4I53 A;  4LST G;  2NY5 G;  5I9Q A;  4RZ8 A;  4XVS G;  5CD5 A;  2BF1 A;  3SE9 G;  5F9W A;  4RFO G;  4XNZ A;  5IGX G;  4DVW A;  3TIH A;  4DKV A;  4R4N A;  2B4C G;  4R4F A;  4DVX A;  4R2G A;  2NY6 A;  4YDI G;  1RZK G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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