2IK6A

Yeast inorganic pyrophosphatase variant d120e with magnesium and phosphate
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
282
structure length
268
Chain Sequence
TYTTRQIGAKNTLEYKVYIEKDGKPVSAFHDIPLYADKENNIFNMVVEIPRWTNAKLEITKEETLNPIIQDTKKGKLRFVRNCFPHHGYIHNYGAFPQTWEDPGDNDPIEVLEIGETIAYTGQVKQVKALGIMALLDEGETDWKVIAIDINDPLAPKLNDIEDVEKYFPGLLRATNEWFRIYKIPDGKPENQFAFSGEAKNKKYALDIIKETHDSWKQLIAGSKGIDLTNVTLPDTPTYSKAASDAIPPASLKADAPIDKSIDKWFFI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Complete Structural Description of the Catalytic Cycle of Yeast Pyrophosphatase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Saccharomyces cerevisiae
molecule keywords Inorganic pyrophosphatase
total genus 78
structure length 268
sequence length 282
chains with identical sequence B
ec nomenclature ec 3.6.1.1: Inorganic diphosphatase.
pdb deposition date 2006-10-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00719 Pyrophosphatase Inorganic pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.80.10 Alpha Beta Alpha-Beta Complex Inorganic Pyrophosphatase Inorganic pyrophosphatase 2ik6A00
3EMJA 2IHPA 5KDEA 3EIZA 2IK1A 1QEZA 1E9GA 1MJXA 1SXVA 1PYPA 3I98A 1MJWA 2BQXA 3Q4WA 3R6EA 1INOA 1WGIA 1HUJA 1YGZA 3SW5A 4ECPA 4Z73A 2EIPA 4Z74A 2IK9A 3GVFA 4LUGA 1IPWA 3D63A 1WCFA 1WGJA 2IK7A 2AU8A 1IGPA 3Q5VA 3Q46A 3FQ3A 4QMBA 1YPPA 2BQYA 2PRDA 1M38A 4QLZA 1I6TA 3LD3A 1TWLA 1UDEA 1HUKA 5H4FA 3R5UA 2AU7A 3TR4A 3LO0A 4Z71A 1MJZA 2IK4A 4XELA 8PRKA 4UM4A 3EJ0A 1OBWA 2AU9A 1MJYA 2IK6A 3EIYA 5TEAA 3I4QA 3R5VA 1I40A 1JFDA 2UXSA 1FAJA 2IK2A 2AU6A 3D53A 4Z72A 2AUUA 117EA 4Z70A 3Q3LA 3EJ2A 1E6AA 5KDFA 2IK0A
chains in the Genus database with same CATH superfamily
3EMJA 2IHPA 5KDEA 3EIZA 2IK1A 1QEZA 1E9GA 1MJXA 1SXVA 1PYPA 3I98A 1MJWA 2BQXA 3Q4WA 3R6EA 1INOA 1WGIA 1HUJA 1YGZA 3SW5A 4ECPA 4Z73A 2EIPA 4Z74A 2IK9A 3GVFA 4LUGA 1IPWA 3D63A 1WCFA 1WGJA 2IK7A 2AU8A 1IGPA 3Q5VA 3Q46A 3FQ3A 4QMBA 1YPPA 2BQYA 2PRDA 1M38A 4QLZA 1I6TA 3LD3A 1TWLA 1UDEA 1HUKA 5H4FA 3R5UA 2AU7A 3TR4A 3LO0A 4Z71A 1MJZA 2IK4A 4XELA 8PRKA 4UM4A 3EJ0A 1OBWA 2AU9A 1MJYA 2IK6A 3EIYA 5TEAA 3I4QA 3R5VA 1I40A 1JFDA 2UXSA 1FAJA 2IK2A 2AU6A 3D53A 4Z72A 2AUUA 117EA 4Z70A 3Q3LA 3EJ2A 1E6AA 5KDFA 2IK0A
chains in the Genus database with same CATH topology
3EMJA 2IHPA 5KDEA 3EIZA 2IK1A 1QEZA 1E9GA 1MJXA 1SXVA 1PYPA 3I98A 1MJWA 2BQXA 3Q4WA 3R6EA 1INOA 1WGIA 1HUJA 1YGZA 3SW5A 4ECPA 4Z73A 2EIPA 4Z74A 2IK9A 3GVFA 4LUGA 1IPWA 3D63A 1WCFA 1WGJA 2IK7A 2AU8A 1IGPA 3Q5VA 3Q46A 3FQ3A 4QMBA 1YPPA 2BQYA 2PRDA 1M38A 4QLZA 1I6TA 3LD3A 1TWLA 1UDEA 1HUKA 5H4FA 3R5UA 2AU7A 3TR4A 3LO0A 4Z71A 1MJZA 2IK4A 4XELA 8PRKA 4UM4A 3EJ0A 1OBWA 2AU9A 1MJYA 2IK6A 3EIYA 5TEAA 3I4QA 3R5VA 1I40A 1JFDA 2UXSA 1FAJA 2IK2A 2AU6A 3D53A 4Z72A 2AUUA 117EA 4Z70A 3Q3LA 3EJ2A 1E6AA 5KDFA 2IK0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EMJ A;  2IHP A;  5KDE A;  3EIZ A;  2IK1 A;  1QEZ A;  1E9G A;  1MJX A;  1SXV A;  1PYP A;  3I98 A;  1MJW A;  2BQX A;  3Q4W A;  3R6E A;  1INO A;  1WGI A;  1HUJ A;  1YGZ A;  3SW5 A;  4ECP A;  4Z73 A;  2EIP A;  4Z74 A;  2IK9 A;  3GVF A;  4LUG A;  1IPW A;  3D63 A;  1WCF A;  1WGJ A;  2IK7 A;  2AU8 A;  1IGP A;  3Q5V A;  3Q46 A;  3FQ3 A;  4QMB A;  1YPP A;  2BQY A;  2PRD A;  1M38 A;  4QLZ A;  1I6T A;  3LD3 A;  1TWL A;  1UDE A;  1HUK A;  5H4F A;  3R5U A;  2AU7 A;  3TR4 A;  3LO0 A;  4Z71 A;  1MJZ A;  2IK4 A;  4XEL A;  8PRK A;  4UM4 A;  3EJ0 A;  1OBW A;  2AU9 A;  1MJY A;  2IK6 A;  3EIY A;  5TEA A;  3I4Q A;  3R5V A;  1I40 A;  1JFD A;  2UXS A;  1FAJ A;  2IK2 A;  2AU6 A;  3D53 A;  4Z72 A;  2AUU A;  117E A;  4Z70 A;  3Q3L A;  3EJ2 A;  1E6A A;  5KDF A;  2IK0 A; 
#chains in the Genus database with same CATH topology
 3EMJ A;  2IHP A;  5KDE A;  3EIZ A;  2IK1 A;  1QEZ A;  1E9G A;  1MJX A;  1SXV A;  1PYP A;  3I98 A;  1MJW A;  2BQX A;  3Q4W A;  3R6E A;  1INO A;  1WGI A;  1HUJ A;  1YGZ A;  3SW5 A;  4ECP A;  4Z73 A;  2EIP A;  4Z74 A;  2IK9 A;  3GVF A;  4LUG A;  1IPW A;  3D63 A;  1WCF A;  1WGJ A;  2IK7 A;  2AU8 A;  1IGP A;  3Q5V A;  3Q46 A;  3FQ3 A;  4QMB A;  1YPP A;  2BQY A;  2PRD A;  1M38 A;  4QLZ A;  1I6T A;  3LD3 A;  1TWL A;  1UDE A;  1HUK A;  5H4F A;  3R5U A;  2AU7 A;  3TR4 A;  3LO0 A;  4Z71 A;  1MJZ A;  2IK4 A;  4XEL A;  8PRK A;  4UM4 A;  3EJ0 A;  1OBW A;  2AU9 A;  1MJY A;  2IK6 A;  3EIY A;  5TEA A;  3I4Q A;  3R5V A;  1I40 A;  1JFD A;  2UXS A;  1FAJ A;  2IK2 A;  2AU6 A;  3D53 A;  4Z72 A;  2AUU A;  117E A;  4Z70 A;  3Q3L A;  3EJ2 A;  1E6A A;  5KDF A;  2IK0 A; 
#chains in the Genus database with same CATH homology
 3EMJ A;  2IHP A;  5KDE A;  3EIZ A;  2IK1 A;  1QEZ A;  1E9G A;  1MJX A;  1SXV A;  1PYP A;  3I98 A;  1MJW A;  2BQX A;  3Q4W A;  3R6E A;  1INO A;  1WGI A;  1HUJ A;  1YGZ A;  3SW5 A;  4ECP A;  4Z73 A;  2EIP A;  4Z74 A;  2IK9 A;  3GVF A;  4LUG A;  1IPW A;  3D63 A;  1WCF A;  1WGJ A;  2IK7 A;  2AU8 A;  1IGP A;  3Q5V A;  3Q46 A;  3FQ3 A;  4QMB A;  1YPP A;  2BQY A;  2PRD A;  1M38 A;  4QLZ A;  1I6T A;  3LD3 A;  1TWL A;  1UDE A;  1HUK A;  5H4F A;  3R5U A;  2AU7 A;  3TR4 A;  3LO0 A;  4Z71 A;  1MJZ A;  2IK4 A;  4XEL A;  8PRK A;  4UM4 A;  3EJ0 A;  1OBW A;  2AU9 A;  1MJY A;  2IK6 A;  3EIY A;  5TEA A;  3I4Q A;  3R5V A;  1I40 A;  1JFD A;  2UXS A;  1FAJ A;  2IK2 A;  2AU6 A;  3D53 A;  4Z72 A;  2AUU A;  117E A;  4Z70 A;  3Q3L A;  3EJ2 A;  1E6A A;  5KDF A;  2IK0 A; 
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